Latest & greatest articles for copd

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on copd or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on copd and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for copd

181. The population attributable fraction of occupational COPD among Danish women Full Text available with Trip Pro

The population attributable fraction of occupational COPD among Danish women The PAF of occupational COPD among Danish women http://ow.ly/CEmy308XEgl.

2017 ERJ open research

182. A qualitative study of women's experiences of living with COPD Full Text available with Trip Pro

A qualitative study of women's experiences of living with COPD To explore women's experiences of living with chronic obstructive pulmonary disease (COPD) at home.An explorative and descriptive qualitative design.A consecutive sample of nine women with COPD living at home. Data were collected in 2014 using semi-structured interviews and analysed using a qualitative content analysis.Three main themes were identified: having a good life with COPD despite limitations; predictability and confidence (...) in getting help; and the struggle to achieve a balance between insight and compliance with management of COPD. These women experienced limitations related to the traditional female role and felt unable to fulfil their own expectations. They experienced a good life despite limitations arising from adaptation and coping strategies. To feel safe, they needed to feel confident that they would receive the necessary help in case of exacerbation of their disease. To enhance compliance with COPD management

2017 Nursing open

183. Chronic obstructive pulmonary disease. (Abstract)

Chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease (COPD) kills more than 3 million people worldwide every year. Despite progress in the treatment of symptoms and prevention of acute exacerbations, few advances have been made to ameliorate disease progression or affect mortality. A better understanding of the complex disease mechanisms resulting in COPD is needed. Smoking cessation programmes, increasing physical activity, and early detection and treatment (...) of comorbidities are further key components to reduce the burden of the disease. However, without a global political and economic effort to reduce tobacco use, to regulate environmental exposure, and to find alternatives to the massive use of biomass fuel, COPD will remain a major health-care problem for decades to come.Copyright © 2017 Elsevier Ltd. All rights reserved.

2017 Lancet

184. CRACKCast E074 – COPD

to Global Initiative for Chronic Obstructive Lung Disease (GOLD), COPD is: “a preventable and treatable disease with some significant extra-pulmonary effects that may contribute to the severity in individual patients. Its pulmonary component is characterized by airflow limitation that is not fully reversible… the airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases.” This used to include elements of reversible airflow (...) limitation (i.e. asthma) and chronic bronchitis (increased sputum for x 3 months for last 2 consecutive years, +/- airflow limitation) Don’t make the rookie mistake of mixing up COPD and emphysema: The latter is a destructive process. Classically centrilobular emphysema is a component of COPD. Alternatively, severe panacinar emphysema is associated with α1- antitrypsin deficiency, an enzyme that inhibits neutrophil elastase (ie stops your neutrophils from melting your lung parenchyma) (Big shout out

2017 CandiEM

185. Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk Full Text available with Trip Pro

Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk Cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) often coexist. We assessed the effect of inhaled COPD treatments on CVD outcomes and safety in patients with COPD and at heightened CVD risk.The SUMMIT (Study to Understand Mortality and MorbidITy) was a multicentre, randomised, double-blind, placebo-controlled, event-driven trial in 16 485 patients (...) , including palpitations and arrhythmias, did not differ by treatment.In patients with COPD with moderate airflow limitation and heightened CVD risk, treatment with inhaled VI, FF or their combination has an excellent safety profile and does not impact CVD outcomes.NCT01313676.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2017 EvidenceUpdates

186. Intermittent cortisone injection for treatment of osteoarthritis and chronic obstructive lung disease

Intermittent cortisone injection for treatment of osteoarthritis and chronic obstructive lung disease Upprepad intramuskulär injektion med kortison för att behandla artros och kroniskt obstruktiv lungsjukdom Vi använder cookies för att optimera webbplatsen på bästa sätt. Om du fortsätter innebär det att du accepterar att cookies används. Statens beredning för medicinsk och social utvärdering Upprepad intramuskulär injektion med kortison för att behandla artros och kroniskt obstruktiv (...) glucocorticoid injections in patients with very early inflammatory polyarthritis: results of the STIVEA trial. In: Annals of the rheumatic diseases; 2010. p 503-9. Dorleijn DM, Luijsterburg PA, Reijman M, Kloppenburg M, Verhaar JA, Bindels PJ, et al. Intramuscular corticosteroid injection versus placebo effective in pain reduction in patients with hip osteoarthritis. Osteoarthritis and Cartilage 2016;24 SUPPL. 1:183-5. Eiser N, Phillips C, Wooler P, Partridge M. Comparison of oral and depot intra-muscular

2017 Swedish Council on Technology Assessement

187. Targeted lung denervation by catheter ablation in chronic obstructive lung disease: Assessments according to õ137h SGB V

Lungendenervierung durch Katheterablation bei chronisch obstruktiver Lungenerkrankung: Bewertungen gemäß § 137h SGB V; Auftrag H16-01. [Targeted lung denervation by catheter ablation in chronic obstructive lung disease: Assessments according to §137h SGB V] Cologne: Institut fuer Qualitaet und Wirtschaftlichkeit im Gesundheitswesen (IQWiG). IQWiG-Berichte 479. 2017 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Catheter Ablation; Denervation; Humans; Lung; Pulmonary Disease, Chronic (...) Targeted lung denervation by catheter ablation in chronic obstructive lung disease: Assessments according to õ137h SGB V Gezielte Lungendenervierung durch Katheterablation bei chronisch obstruktiver Lungenerkrankung: Bewertungen gemäß § 137h SGB V; Auftrag H16-01 [Targeted lung denervation by catheter ablation in chronic obstructive lung disease: Assessments according to §137h SGB V] Gezielte Lungendenervierung durch Katheterablation bei chronisch obstruktiver Lungenerkrankung: Bewertungen

2017 Health Technology Assessment (HTA) Database.

188. Palliative and end-of-life care conversations in COPD: a systematic literature review Full Text available with Trip Pro

Palliative and end-of-life care conversations in COPD: a systematic literature review Chronic obstructive pulmonary disease (COPD) is a chronic life-limiting disorder characterised by persistent airflow obstruction and progressive breathlessness. Discussions/conversations between patients and clinicians ensure palliative care plans are grounded in patients' preferences. This systematic review aimed to explore what is known about palliative care conversations between clinicians and COPD patients (...) conversations is generally poor. Patients and physicians identified many barriers and important topics were not discussed. Patients and clinicians reported tension between remaining hopeful and the reality of the patients' condition. When discussions did happen, they often occurred at an advanced stage of illness and in respiratory wards and intensive care units. In conclusion, current care practices do not facilitate satisfactory conversations about palliative care between COPD patients and clinicians

2017 ERJ open research

189. Procalcitonin and CRP as Biomarkers in Discrimination of Community-acquired Pneumonia and Exacerbation of COPD Full Text available with Trip Pro

Procalcitonin and CRP as Biomarkers in Discrimination of Community-acquired Pneumonia and Exacerbation of COPD Serum procalcitonin (PCT) and C-reactive protein (CRP) are markers of systemic inflammation and bacterial infection. We aimed to compare the usefulness of procalcitonin and CRP in patients with community-acquired pneumonia and exacerbations of chronic obstructive pulmonary disease (COPD).A total of 116 consecutive patients were included in the study: 76 with chronic obstructive (...) pneumonia.Procalcitonin and CRP levels were significantly higher in patients with community-acquired pneumonia presenting to the emergency department with indications for hospitalization than in patients with exacerbations of chronic obstructive pulmonary disease. Serum CRP and procalcitonin concentrations were strongly correlated. CRP might be a more valuable marker in these patients with lower respiratory tract infections.

2017 Journal of medical biochemistry

190. Evaluation of symptoms and risks in stable chronic obstructive pulmonary disease patients with radiographic bronchiectasis Full Text available with Trip Pro

Evaluation of symptoms and risks in stable chronic obstructive pulmonary disease patients with radiographic bronchiectasis To investigate the presence of previously undiagnosed radiographic bronchiectasis in stable chronic obstructive pulmonary disease (COPD) patients using high resolution computed tomography (HRCT) and to evaluate the effect of radiographic bronchiectasis on the symptoms and risks in stable COPD patients.From May 2012 to April 2014, there were 347 patients enrolled in COPD (...) database. Data describing the general conditions, the frequency of acute exacerbations the year before, COPD assessment test, modified medical research council (mMRC) score, spirometric classification, and HRCT were collected. COPD patients were classified into two groups: COPD with bronchiectasis and COPD without bronchiectasis. The clinical characteristics of both groups were compared.Bronchiectasis was presented in 18.4% (n = 64). The proportion of smokers, smoking index, and forced expiratory

2017 Chronic diseases and translational medicine

191. Small airway imaging phenotypes in biomass- and tobacco smoke-exposed patients with COPD Full Text available with Trip Pro

Small airway imaging phenotypes in biomass- and tobacco smoke-exposed patients with COPD Biomass and functional small airway disease http://ow.ly/gXu730abpKu.

2017 ERJ open research

192. Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial. Full Text available with Trip Pro

Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial. Limited data are available for the efficacy of triple therapy with two long-acting bronchodilators and an inhaled corticosteroid in chronic obstructive pulmonary disease (COPD). We compared treatment with extrafine beclometasone dipropionate, formoterol fumarate, and glycopyrronium bromide (BDP (...) tiotropium, patients were randomised (2:2:1) using a interactive response technology system to 52 weeks treatment with tiotropium, fixed triple, or open triple. Randomisation was stratified by country and severity of airflow limitation. The primary endpoint was moderate-to-severe COPD exacerbation rate. The key secondary endpoint was change from baseline in pre-dose FEV1 at week 52. The trial is registered with ClinicalTrials.gov, number NCT01911364.Between Jan 21, 2014, and March 18, 2016, 2691 patients

2017 Lancet Controlled trial quality: predicted high

193. Umeclidinium (Rolufta) - COPD

with chronic obstructive pulmonary disease (COPD). The legal basis for this application refers to: Article 10(c) of Directive 2001/83/EC – relating to informed consent from a marketing authorisation holder for an authorised medicinal product. The application submitted is composed of administrative information, quality, non-clinical and clinical data with a letter from GlaxoSmithKline Trading Services Limited allowing the cross reference to relevant quality, non-clinical and/or clinical data. Information (...) inhalers containing 30 doses each. The benefit-risk of Rolufta is considered to be positive, as it is a duplicate of Incruse, in the following indication: • Rolufta is indicated as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD). Umeclidinium bromide is a long acting muscarinic receptor antagonist administrated by inhalation. It is competitively inhibiting the binding of acetylcholine with muscarinic cholinergic receptors

2017 European Medicines Agency - EPARs

194. Chronic Obstructive Pulmonary Disease (COPD): Diagnosis and Management

failure and pneumonia are the leading causes of morbidity and mortality. However, even in these patients, cardiovascular diseases remain a major concern. 52 BCGuidelines.ca: Chronic Obstructive Pulmonary Disease (COPD): Diagnosis and Management (2017) Diagnosis While a diagnosis is based on a combination of medical history and physical examination, it is the documentation of air#ow limitation using spirometry that con"rms the diagnosis. Consider a COPD diagnosis for a patient = 40 years of age who has (...) Chronic Obstructive Pulmonary Disease (COPD): Diagnosis and Management ' ? s E G u s Y G ? T W ? Ž l Ž Ð Ž u ? E | s ? Ž ? ? Ž w w s ? G G Chronic Obstructive Pulmonary Disease (COPD): Diagnosis and Management E ective Date: February 22, 2017 Scope This guideline provides recommendations for the diagnosis and management of adults aged = 19 years with chronic obstructive pulmonary disease (COPD). Key Recommendations • Use spirometry to con$rm air%ow obstruction in all patients suspected

2017 Clinical Practice Guidelines and Protocols in British Columbia

195. Oxygen Saturation Target of 88-92% in COPD: Evidence-based Medicine?

chronic obstructive lung disease: a clinical trial. Nocturnal Oxygen Therapy Trial Group. Ann Intern Med. 1980;93(3):391-398. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working Party. Lancet. 1981;1(8222):681-686. Górecka D, Gorzelak K, Sliwiński P, Tobiasz M, Zieliński J. Effect of long-term oxygen therapy on survival in patients with chronic obstructive pulmonary disease with moderate (...) by Harald Sauthoff, MD, Pulmonary Medicine, NYU Langone Medical Center Image courtesy of Wikimedia Commons References Qaseem A, Wilt TJ, Weinberger SE, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med. 2011;155(3):179-191. National Institute for Health and Care Excellence (NICE

2017 Clinical Correlations

196. Use Of Diode Lasers in Addition to Conventional Non-Surgical Periodontal Therapy Does Not Produce a Decrease in Probing Depths or Clinical Attachment Loss (CAL)

in the initial phase of chronic periodontal therapy, does adjunctive treatment with diode lasers result in decreased probing depth and clinical attachment loss (CAL) as compared to those treated with conventional non-surgical periodontal therapy? Clinical Bottom Line The use of diode lasers in addition to scaling and root planing does not produce a decrease in probing depths or CAL for those undergoing the initial phase of chronic periodontal treatment. A review of 9 studies including a large number (...) ]. CAL DiffM = 0.04, p = 0.80, 95% CI [-0.26, 0.34]. Evidence Search ("chronic periodontitis"[MeSH Terms] OR ("chronic"[All Fields] AND "periodontitis"[All Fields]) OR "chronic periodontitis"[All Fields]) AND ("lasers"[MeSH Terms] OR "lasers"[All Fields] OR "laser"[All Fields]) AND Review[ptyp] Comments on The Evidence Validity: The review included a detailed search for relevant trials with strict selection parameters. Two independent reviewers assessed all studies for methodological quality. Meta

2017 UTHSCSA Dental School CAT Library

197. Does Telehealth Monitoring Identify Exacerbations of Chronic Obstructive Pulmonary Disease and Reduce Hospitalisations? An Analysis of System Data Full Text available with Trip Pro

Does Telehealth Monitoring Identify Exacerbations of Chronic Obstructive Pulmonary Disease and Reduce Hospitalisations? An Analysis of System Data The increasing prevalence and associated cost of treating chronic obstructive pulmonary disease (COPD) is unsustainable. Health care organizations are focusing on ways to support self-management and prevent hospital admissions, including telehealth-monitoring services capturing physiological and health status data. This paper reports on data captured (...) during a pilot randomized controlled trial of telehealth-supported care within a community-based service for patients discharged from hospital following an exacerbation of their COPD.The aim was to undertake the first analysis of system data to determine whether telehealth monitoring can identify an exacerbation of COPD, providing clinicians with an opportunity to intervene with timely treatment and prevent hospital readmission.A total of 23 participants received a telehealth-supported intervention

2017 JMIR medical informatics Controlled trial quality: uncertain

198. Cardiopulmonary response during whole-body vibration training in patients with severe COPD Full Text available with Trip Pro

Cardiopulmonary response during whole-body vibration training in patients with severe COPD Several studies in patients with chronic obstructive pulmonary disease (COPD) have shown that whole-body vibration training (WBVT) has beneficial effects on exercise capacity. However, the acute cardiopulmonary demand during WBVT remains unknown and was therefore investigated in this study. Ten patients with severe COPD (forced expiratory volume in 1 s: 38±8% predicted) were examined on two consecutive (...) days. On day one, symptom-limited cardiopulmonary exercise testing was performed on a cycle ergometer. The next day, six bouts of repeated squat exercises were performed in random order for one, two or three minutes either with or without WBVT while metabolic demands were simultaneously measured. Squat exercises with or without WBVT induced comparable ventilatory efficiency (minute ventilation (VE)/carbon dioxide production (V'CO2 ): 38.0±4.4 with WBVT versus 37.4±4.1 without, p=0.236). Oxygen

2017 ERJ open research

199. Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease. Full Text available with Trip Pro

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease. In the recent years, a variety of bronchoscopic lung volume reduction (BLVR) procedures have emerged that may provide a treatment option to participants suffering from moderate to severe chronic obstructive pulmonary disease (COPD).To assess the effects of BLVR on the short- and long-term health outcomes in participants with moderate to severe COPD and determine the effectiveness and cost-effectiveness (...) of each individual technique.Studies were identified from the Cochrane Airways Group Specialised Register (CAGR) and by handsearching of respiratory journals and meeting abstracts. All searches are current until 07 December 2016.We included randomized controlled trials (RCTs). We included studies reported as full text, those published as abstract only and unpublished data, if available.Two independent review authors assessed studies for inclusion and extracted data. Where possible, data from more than

2017 Cochrane

200. Community pharmacy COPD services: what do researchers and policy makers need to know? Full Text available with Trip Pro

an opportunity to assist the patient in managing their condition and working more closely with the rest of the primary care team. While there are a number of robust studies which have demonstrated the role which pharmacists could undertake to identify and prevent disease progression, adoption of such services is currently limited. As a service that would seem to be appropriate for adoption in all societies where smoking is prevalent, we have performed a review of reported approaches that have been used when (...) Community pharmacy COPD services: what do researchers and policy makers need to know? COPD is a leading cause of morbidity and mortality across the world and is responsible for a disproportionate use of health care resources. It is a progressive condition that is largely caused by smoking. Identification of early stage COPD provides an opportunity for interventions, such as smoking cessation, which prevent its progression. Once diagnosed, ongoing support services potentially provide

2017 Integrated pharmacy research & practice