Latest & greatest articles for clonidine

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on clonidine or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on clonidine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for clonidine

41. Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial.

Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial. 3367452 1988 06 10 1988 06 10 2016 10 17 0098-7484 259 19 1988 May 20 JAMA JAMA Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial. 2863-6 Seventy-one heavy smokers who had failed in previous attempts to stop smoking participated in a randomized clinical trial to test the efficacy of clonidine as an aid in smoking cessation. The success rate in clonidine (...) -treated subjects (verified by serum cotinine concentration) was more than twice that in the placebo-treated subjects. When the data were stratified by gender, a strong effect present in women was not apparent in men. After six months, cessation rates remained significantly higher among smokers treated with clonidine than those receiving placebo. The data also revealed an unexpectedly high prevalence (61%) of a history of major depression in this sample and a significant negative effect

JAMA1988

42. Lack of benefit of clonidine treatment for short stature in a double-blind, placebo-controlled trial.

Lack of benefit of clonidine treatment for short stature in a double-blind, placebo-controlled trial. 2902319 1988 11 10 1988 11 10 2015 06 16 0140-6736 2 8616 1988 Oct 15 Lancet (London, England) Lancet Lack of benefit of clonidine treatment for short stature in a double-blind, placebo-controlled trial. 874-7 Twelve short (more than two standard deviations below the mean height for age), prepubertal children (ten boys, two girls) who had a normal peak growth hormone (GH) response (...) to provocative stimulation with clonidine (more than 10 ng/ml) were enrolled in a double-blind, placebo-controlled, crossover study of the effects of a single, nightly dose of clonidine (0.1 mg/m2 by mouth). The children's mean age was 7.2 years (range 3.6-10.5 years). The results of 6 months of clonidine therapy were compared with those of 6 months of placebo. Clonidine therapy resulted in no significant difference in height standard deviation score, growth velocity, bone age, 24 h integrated GH

Lancet1988

43. Clonidine blocks acute opiate-withdrawal symptoms.

Clonidine blocks acute opiate-withdrawal symptoms. 80526 1978 11 18 1978 11 18 2015 06 16 0140-6736 2 8090 1978 Sep 16 Lancet (London, England) Lancet Clonidine blocks acute opiate-withdrawal symptoms. 599-602 In a double-blind, placebo-controlled, cross-over trial, clonidine eliminated objective signs and subjective symptoms of opiate withdrawal for 240--360 min in eleven addicts in a hospital setting. In an open pilot study of the effects of clonidine on longer-term opiate abstinence (...) and symptoms, the same patients did well while taking clonidine for one week. There was only one documented instance of heroin use, in a patient who did not take clonidine after hospital discharge. 6 weeks or more after the study, four patients were back on reduced doses of methadone, one was on tricyclic antidepressants, and seven were off of all opiates. All eleven patients were doing well. These data suggest that opiate withdrawal is due to increased neuronal activity in areas such as the locus

Lancet1978