Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for clonidine
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on clonidine or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on clonidine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via firstname.lastname@example.org
Can clonidine be used in effectively in epidural and intrathecal catheters? Can clonidine be used in effectively in epidural and intrathecal catheters? Can clonidine be used in effectively in epidural and intrathecal catheters? Wasiak J Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Wasiak J. Can clonidine be used in effectively in epidural and intrathecal (...) catheters? Clayton, Victoria: Centre for Clinical Effectiveness (CCE) 2000: 17 Authors' objectives This aim of this report was to assess whether clondine can be used in effectively in epidural and intrathecal catheters. Authors' conclusions - The largest reported experience with clonidine for regional anaesthesia is with epidural administration. - Published reports of epidural clonidine have been in the areas of chronic pain, intra- and post-operative pain, and in obstetric and paediatric populations
Clonidine for smoking cessation. Clonidine was originally used to lower blood pressure. It acts on the central nervous system and may reduce withdrawal symptoms in various addictive behaviours, including tobacco use.The aim of this review is to determine clonidine's effectiveness in helping smokers to quit.We searched the Cochrane Tobacco Addiction Group trials register. Date of the most recent search: October 1998.We considered randomised trials of clonidine versus placebo with a smoking (...) cessation endpoint assessed at least 12 weeks following the end of treatment.We extracted data in duplicate on the type of subjects, the dose and duration of clonidine therapy, the outcome measures, method of randomisation, and completeness of follow-up. The main outcome measure was abstinence from smoking after at least twelve weeks follow-up in patients smoking at baseline. We used the most rigorous definition of abstinence for each trial, and biochemically validated rates if available. Where
A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Pharmacy savings generated by preoperative administration of clonidine Pharmacy savings generated by preoperative administration of clonidine Pharmacy savings generated by preoperative administration of clonidine Valles J, Samso E, Vilar X, Gallart L, Puig M M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical (...) assessment on the reliability of the study and the conclusions drawn. Health technology Preoperative administration of clonidine in patients undergoing total abdominal hysterectomy with inhalational anaesthesia. Type of intervention Anaesthesia; Treatment. Economic study type Cost-effectiveness analysis. Study population Women undergoing total abdominal hysterectomy (TAH) with inhalational anaesthesia. Setting Secondary care. The economic study was conducted in a university hospital in Barcelona, Spain
The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia Imai Y, Mammoto T, Murakami K, Kita T, Sakai T, Kagawa K, Kirita T, Sugimura M, Kishi Y Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion (...) on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of preanaesthetic oral clonidine or diazepam, administered to patients prior to propofol, to induce anaesthesia in minor breast conserving surgery. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised
Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Curatolo M, Petersen-Felix S, Scaramozzino P, Zbinden A M (...) Authors' objectives To assess the effectiveness of adding fentanyl, adrenaline and clonidine to local anaesthetics for intra-operative epidural analgesia not combined with general anaesthesia. Searching MEDLINE (from 1966), Excerpta Medica (from 1974), and the Science Citation Index (from 1980) were searched using the keywords 'anesthetic techniques', 'epidural', fentanyl', 'epinephrine' and 'clonidine'. In addition, the authors' databases, abstracts of anaesthesia meetings (details listed
Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Armand S, Langlade A, Boutros A, Lobjoit K, Monrigal C, Ramboatiana R, Rauss A, Bonnet F Authors' objectives To assess the efficacy of extradural clonidine in the relief of post-operative (...) pain, to determine whether anti-nociceptive effects and side-effects were dose-related, and to what extent the latter were deleterious. Searching The databases of MEDLINE and Excerpta Medica were searched from 1985 to 1997 using the following headings: regional analgesia; extradural clonidine; postoperative analgesia; and postoperative pain. Citations from articles were cross-referenced with those in the assessor's bibliography and those of the articles under review. Study selection Study designs
A trial of clonidine to stop smoking. 2185371 1990 06 07 2016 10 17 0098-7484 263 20 1990 May 23-30 JAMA JAMA A trial of clonidine to stop smoking. 2746-7 eng Clinical Trial Comment Letter Randomized Controlled Trial United States JAMA 7501160 0098-7484 MN3L5RMN02 Clonidine AIM IM JAMA. 1989 Dec 1;262(21):3011-3 2681856 Behavior Therapy Clonidine administration & dosage therapeutic use Double-Blind Method Humans Randomized Controlled Trials as Topic Smoking drug therapy 1990 5 23 1990 5 23 0 1
Randomized, controlled trial of clonidine for smoking cessation in a primary care setting. Clonidine hydrochloride has been reported to reduce tobacco withdrawal symptoms and facilitate smoking cessation. We enrolled 185 subjects, 92 receiving clonidine and 93 receiving placebo, in a randomized, double-blind study of clonidine for smoking cessation in a primary care setting. Clonidine had no demonstrable effect on withdrawal (8 of 11 measures favoring placebo). At 4 weeks, 17 (18%) subjects (...) receiving clonidine had quit compared with 13 (14%) receiving placebo (chi 2 = 0.7; 90% confidence interval of benefit from clonidine, -4% to 13%). At 4 weeks, the mean number of cigarettes smoked was 17.7 for those receiving clonidine and 17.5 for those receiving placebo (t = 0.1; 90% confidence interval of benefit from clonidine, -4.1 to 3.7 cigarettes per day). These results provide little support for a beneficial effect of clonidine on tobacco withdrawal symptoms, quitting, or smoking reduction
Lack of benefit of clonidine treatment for short stature in a double-blind, placebo-controlled trial. Twelve short (more than two standard deviations below the mean height for age), prepubertal children (ten boys, two girls) who had a normal peak growth hormone (GH) response to provocative stimulation with clonidine (more than 10 ng/ml) were enrolled in a double-blind, placebo-controlled, crossover study of the effects of a single, nightly dose of clonidine (0.1 mg/m2 by mouth). The children's (...) mean age was 7.2 years (range 3.6-10.5 years). The results of 6 months of clonidine therapy were compared with those of 6 months of placebo. Clonidine therapy resulted in no significant difference in height standard deviation score, growth velocity, bone age, 24 h integrated GH concentration, peak GH response to clonidine stimulation, levels of insulin-like growth factor 1, or predicted height by the RWT method. In contrast to other studies, this study shows no sustained increases in GH production
Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial. Seventy-one heavy smokers who had failed in previous attempts to stop smoking participated in a randomized clinical trial to test the efficacy of clonidine as an aid in smoking cessation. The success rate in clonidine-treated subjects (verified by serum cotinine concentration) was more than twice that in the placebo-treated subjects. When the data were stratified by gender, a strong effect present (...) in women was not apparent in men. After six months, cessation rates remained significantly higher among smokers treated with clonidine than those receiving placebo. The data also revealed an unexpectedly high prevalence (61%) of a history of major depression in this sample and a significant negative effect of such a history on cessation regardless of treatment. These findings, highly suggestive of an important role of clonidine in smoking cessation, warrant further studies to establish the long-term
Clonidine blocks acute opiate-withdrawal symptoms. In a double-blind, placebo-controlled, cross-over trial, clonidine eliminated objective signs and subjective symptoms of opiate withdrawal for 240--360 min in eleven addicts in a hospital setting. In an open pilot study of the effects of clonidine on longer-term opiate abstinence and symptoms, the same patients did well while taking clonidine for one week. There was only one documented instance of heroin use, in a patient who did not take (...) clonidine after hospital discharge. 6 weeks or more after the study, four patients were back on reduced doses of methadone, one was on tricyclic antidepressants, and seven were off of all opiates. All eleven patients were doing well. These data suggest that opiate withdrawal is due to increased neuronal activity in areas such as the locus coeruleus which are regulated by both alpha-2 adrenergic and opiate receptors.