Latest & greatest articles for clonidine

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Top results for clonidine

21. The efficacy of intrathecal morphine with or without clonidine for postoperative analgesia after radical prostatectomy

The efficacy of intrathecal morphine with or without clonidine for postoperative analgesia after radical prostatectomy 19448230 2009 05 18 2009 06 05 2013 11 21 1526-7598 108 6 2009 Jun Anesthesia and analgesia Anesth. Analg. The efficacy of intrathecal morphine with or without clonidine for postoperative analgesia after radical prostatectomy. 1954-7 10.1213/ane.0b013e3181a30182 In this randomized study, we compared intrathecal (i.t.) morphine with or without clonidine and i.v. postoperative (...) patient-controlled analgesia (PCA) morphine for analgesia after radical retropubic prostatectomy. Fifty patients were randomly divided into three groups. They were allocated to receive i.t. morphine (4 microg/kg) (M group), i.t. morphine and clonidine (1 microg/kg) (MC group), or PCA (PCA group). Each patient was given morphine PCA for postoperative analgesia. The primary objective was the quantity of morphine required during the first 48 postoperative hours. The first request for morphine, numeric

EvidenceUpdates2009

22. Clonidine as an adjunct therapy to opioids for neonatal abstinence syndrome: a randomized, controlled trial.

Clonidine as an adjunct therapy to opioids for neonatal abstinence syndrome: a randomized, controlled trial. 19398463 2009 04 28 2009 05 26 2016 11 22 1098-4275 123 5 2009 May Pediatrics Pediatrics Clonidine as an adjunct therapy to opioids for neonatal abstinence syndrome: a randomized, controlled trial. e849-56 10.1542/peds.2008-0978 To determine if oral clonidine would reduce the duration of opioid detoxification for neonatal abstinence syndrome. Infants with intrauterine exposure (...) to methadone or heroin and neonatal abstinence syndrome (2 consecutive modified Finnegan scores of > or =9) were enrolled at 2 hospitals during 2002-2005 and followed until final hospital discharge. All enrolled infants (80) received oral diluted tincture of opium according to a standardized algorithm and were randomly assigned to receive oral clonidine (1 microg/kg every 4 hours) (40 infants) or placebo (40 infants). Primary outcome was duration of opioid therapy. Secondary outcomes included the amount

EvidenceUpdates2009 Full Text: Link to full Text with Trip Pro

23. The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial

The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial 19151300 2009 01 19 2009 02 09 2013 11 21 1526-7598 108 2 2009 Feb Anesthesia and analgesia Anesth. Analg. The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial. 631-4 10.1213/ane.0b013e31818e61b8 Clonidine is an alpha(2) adrenoreceptor and imidazoline receptor agonist, which has analgesic, sedative, and minimum alveolar anesthetic concentration (...) -sparing effects. It has been used orally, IV, and epidurally. In spinal surgery, there is a reluctance to use local anesthetic-based epidural analgesia postoperatively because of fears of masking important signs of nerve root or spinal cord injury. We randomized 66 patients undergoing uncomplicated decompressive spinal surgery to receive an epidural infusion of either clonidine (Group C) or saline placebo (Group P) postoperatively. Morphine consumption by patient-controlled analgesia device

EvidenceUpdates2009

24. Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials

Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials Popping DM, Elia N, Marret E, Wenk M, Tramer MR CRD summary The authors concluded that adding clonidine to intermediate or long (...) -acting local anaesthetics for single-shot peripheral nerve or plexus blocks prolonged duration of analgesia and motor block, but increased hypotension, fainting and sedation. There were some limitations in the review, but overall evidence appeared to support the authors’ conclusions. Authors' objectives To evaluate the effects of adding clonidine to local anaesthetics for peripheral single-injection nerve or plexus block in adults undergoing surgery without general anaesthetic. Searching MEDLINE

DARE.2009

25. Clonidine and analgesic duration after popliteal fossa nerve blockade: randomized, double-blind, placebo-controlled study

Clonidine and analgesic duration after popliteal fossa nerve blockade: randomized, double-blind, placebo-controlled study 18499632 2008 05 23 2008 06 05 2013 11 21 1526-7598 106 6 2008 Jun Anesthesia and analgesia Anesth. Analg. Clonidine and analgesic duration after popliteal fossa nerve blockade: randomized, double-blind, placebo-controlled study. 1916-20 10.1213/ane.0b013e318172fe44 We tested the hypothesis that 100 microg clonidine added to 0.375% bupivacaine would prolong the duration (...) of analgesia from popliteal fossa nerve blockade. Ninety-nine patients scheduled for hospital admission after foot or ankle surgery entered this randomized, double-blind, placebo-controlled trial. Patients received a popliteal fossa block (nerve stimulator technique, via the posterior approach) using 30 mL 0.375% bupivacaine, with epinephrine. Patients were randomized to receive no clonidine, 100 microg clonidine IM, or 100 microg clonidine with bupivacaine for the popliteal block. Patients also received

EvidenceUpdates2008

26. Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials

Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials Elia N, Culebras X, Mazza C, Schiffer E, Tramer M R CRD summary The authors concluded that adding clonidine to intrathecal local anaesthetic had beneficial effects (...) on some, but not all measures of motor and sensory block. Adding clonidine reduced intra-operative pain but increased the risk of arterial hypotension. Given the low quality of the included studies and the possibility of publication bias, the reliability of the results is questionable. Authors' objectives To assess the efficacy and harm associated with adding clonidine to intrathecal local anaesthetics for surgery. Searching MEDLINE, EMBASE, CINAHL, BIOSIS Previews, INDMED and Cochrane Central

DARE.2008

27. Should we add clonidine to local anesthetic for peripheral nerve blockade: a qualitative systematic review of the literature

Should we add clonidine to local anesthetic for peripheral nerve blockade: a qualitative systematic review of the literature Should we add clonidine to local anesthetic for peripheral nerve blockade: a qualitative systematic review of the literature Should we add clonidine to local anesthetic for peripheral nerve blockade: a qualitative systematic review of the literature McCartney C J, Duggan E, Apatu E CRD summary Clonidine improved the duration of analgesia and anaesthesia when used (...) as an adjunct to intermediate-acting local anaesthetics for some peripheral nerve blocks. The authors' conclusions reflected the evidence presented, but in light of both a lack of reporting, and the presence of several methodological concerns with the review, the authors' conclusions may not be reliable. Authors' objectives To determine the effectiveness of adding clonidine to local anaesthetics for peripheral nerve block. Searching PubMed and EMBASE were searched from July 1991 to October 2006 for English

DARE.2007

28. Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects

Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Article Text Therapeutics Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Free Charles J Bentz , MD Statistics from Altmetric.com No Altmetric

Evidence-Based Medicine (Requires free registration)2006

29. Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial.

Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial. 16118380 2005 08 24 2005 08 30 2016 10 17 1538-3598 294 8 2005 Aug 24 JAMA JAMA Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial. 903-13 Rapid opioid detoxification with opioid antagonist induction using general anesthesia has emerged as an expensive, potentially dangerous, unproven approach (...) opioid detoxification with naltrexone induction, and clonidine-assisted opioid detoxification with delayed naltrexone induction. Withdrawal severity scores on objective and subjective scales; proportions of patients receiving naltrexone, completing inpatient detoxification, and retained in treatment; proportion of opioid-positive urine specimens. Mean withdrawal severities were comparable across the 3 treatments. Compared with clonidine-assisted detoxification, the anesthesia- and buprenorphine

JAMA2005

30. Buprenorphine may be more effective than clonidine and other symptomatic medications for short term ambulatory heroin withdrawal

Buprenorphine may be more effective than clonidine and other symptomatic medications for short term ambulatory heroin withdrawal Buprenorphine may be more effective than clonidine and other symptomatic medications for short term ambulatory heroin withdrawal | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Buprenorphine may be more effective than clonidine and other symptomatic medications for short term ambulatory heroin withdrawal Article Text Therapeutics Buprenorphine may be more effective than clonidine and other symptomatic medications

Evidence-Based Mental Health2004

31. Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature

Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature Nishina K, Mikawa K, Uesugi T, Obara H, Maekawa M, Kamae I, Nishi N Authors' objectives To determine (...) whether clonidine premedication can reduce the occurrence of peri-operative myocardial ischaemia. Searching MEDLINE was searched from 1980 to 1999 using the following MeSH terms: 'myocardial ischaemia', 'coronary disease', 'myocardial infarction', 'coronary arteriosclerosis', 'coronary thrombosis', 'angina pectoris', 'prospective studies', 'clinical trials', 'randomized controlled trials', 'controlled clinical trials', 'intervention studies'. Only English language articles were considered. Personal

DARE.2002

32. Can clonidine be used in effectively in epidural and intrathecal catheters?

Can clonidine be used in effectively in epidural and intrathecal catheters? Can clonidine be used in effectively in epidural and intrathecal catheters? Can clonidine be used in effectively in epidural and intrathecal catheters? Wasiak J Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Wasiak J. Can clonidine be used in effectively in epidural and intrathecal (...) catheters? Clayton, Victoria: Centre for Clinical Effectiveness (CCE) 2000: 17 Authors' objectives This aim of this report was to assess whether clondine can be used in effectively in epidural and intrathecal catheters. Authors' conclusions - The largest reported experience with clonidine for regional anaesthesia is with epidural administration. - Published reports of epidural clonidine have been in the areas of chronic pain, intra- and post-operative pain, and in obstetric and paediatric populations

Health Technology Assessment (HTA) Database.2000

33. Clonidine for smoking cessation.

Clonidine for smoking cessation. BACKGROUND: Clonidine was originally used to lower blood pressure. It acts on the central nervous system and may reduce withdrawal symptoms in various addictive behaviours, including tobacco use. OBJECTIVES: The aim of this review is to determine clonidine's effectiveness in helping smokers to quit. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register. Date of the most recent search: October 1998. SELECTION CRITERIA: We considered (...) randomised trials of clonidine versus placebo with a smoking cessation endpoint assessed at least 12 weeks following the end of treatment. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of subjects, the dose and duration of clonidine therapy, the outcome measures, method of randomisation, and completeness of follow-up. The main outcome measure was abstinence from smoking after at least twelve weeks follow-up in patients smoking at baseline. We used the most rigorous definition

Cochrane2000

34. A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder

A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder Connor D F, Fletcher K E, Swanson J M Authors' objectives To review the literature on the clinical use of clonidine to treat symptoms of attention-deficit hyperactviity disorder (ADHD). Searching The following sources were searched: MEDLINE (...) from 1980 to 1999, PsycINFO from 1984 to 1999, Currents Contents (Social and Behavioural Sciences) from 1996 to 1999), and Currents Contents (Clinical Medicine) from 1996 to 1999. The keywords included the following terms: 'clonidine' alone or in combination with 'attention deficit', 'hyperactivity', 'conduct', 'disruptive behavioural', 'Tourettes's', 'tic', 'autism', 'developmental delay' or 'posttraumatic distress disorder'. Non-peer-reviewed research reports, book chapters, chapter

DARE.1999

35. Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task

Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task Armand S, Langlade A, Boutros A, Lobjoit K, Monrigal C, Ramboatiana R, Rauss A, Bonnet F Authors' objectives To assess the efficacy of extradural clonidine in the relief of post-operative (...) pain, to determine whether anti-nociceptive effects and side-effects were dose-related, and to what extent the latter were deleterious. Searching The databases of MEDLINE and Excerpta Medica were searched from 1985 to 1997 using the following headings: regional analgesia; extradural clonidine; postoperative analgesia; and postoperative pain. Citations from articles were cross-referenced with those in the assessor's bibliography and those of the articles under review. Study selection Study designs

DARE.1998

36. Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects

Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects Curatolo M, Petersen-Felix S, Scaramozzino P, Zbinden A M (...) Authors' objectives To assess the effectiveness of adding fentanyl, adrenaline and clonidine to local anaesthetics for intra-operative epidural analgesia not combined with general anaesthesia. Searching MEDLINE (from 1966), Excerpta Medica (from 1974), and the Science Citation Index (from 1980) were searched using the keywords 'anesthetic techniques', 'epidural', fentanyl', 'epinephrine' and 'clonidine'. In addition, the authors' databases, abstracts of anaesthesia meetings (details listed

DARE.1998

37. The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia

The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia Imai Y, Mammoto T, Murakami K, Kita T, Sakai T, Kagawa K, Kirita T, Sugimura M, Kishi Y Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion (...) on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of preanaesthetic oral clonidine or diazepam, administered to patients prior to propofol, to induce anaesthesia in minor breast conserving surgery. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised

NHS Economic Evaluation Database.1998

38. Pharmacy savings generated by preoperative administration of clonidine

Pharmacy savings generated by preoperative administration of clonidine Pharmacy savings generated by preoperative administration of clonidine Pharmacy savings generated by preoperative administration of clonidine Valles J, Samso E, Vilar X, Gallart L, Puig M M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical (...) assessment on the reliability of the study and the conclusions drawn. Health technology Preoperative administration of clonidine in patients undergoing total abdominal hysterectomy with inhalational anaesthesia. Type of intervention Anaesthesia; Treatment. Economic study type Cost-effectiveness analysis. Study population Women undergoing total abdominal hysterectomy (TAH) with inhalational anaesthesia. Setting Secondary care. The economic study was conducted in a university hospital in Barcelona, Spain

NHS Economic Evaluation Database.1998

39. Epidural bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: quality of postoperative analgesia and cost-identification analysis

Epidural bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: quality of postoperative analgesia and cost-identification analysis Epidural bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: quality of postoperative analgesia and cost-identification analysis Epidural bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: quality of postoperative analgesia and cost-identification analysis Rockemann M G (...) . Epidural bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: quality of postoperative analgesia and cost-identification analysis. Anesthesia and Analgesia 1997; 85(4): 864-869 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Adult; Aged; Analgesia, Epidural /economics; Analgesia, Patient-Controlled /economics; Analgesics /administration & Bupivacaine /administration & Clonidine /administration & Female; Health Care Costs; Humans; Male; Middle Aged; Morphine

NHS Economic Evaluation Database.1997

40. Clonidine for patients with rapid atrial fibrillation.

Clonidine for patients with rapid atrial fibrillation. Clonidine for patients with rapid... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 1992 ) Volume: 116 , Issue: 5 , Pages: 388-390 PubMed: Available from or Find this paper at: Abstract OBJECTIVE: To determine whether clonidine can slow ventricular rate in patients with rapid atrial fibrillation. DESIGN: Randomized, controlled trial (...) either "no treatment" (control group) or clonidine, 0.075 mg orally, at baseline and after 2 hours if heart rate did not decrease by at least 20%. MEASUREMENTS: Blood pressure was measured by the same nurse in the same arm for 4 consecutive hours, and a full 12-lead electrocardiographic evaluation was done. MAIN RESULTS: Heart rate decreased to below 100 beats/min in eight of nine patients receiving clonidine compared with two of nine patients in the control group. The difference in the mean

Annals of Internal Medicine1992