Latest & greatest articles for chronic pain

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on chronic pain or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on chronic pain and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for chronic pain

601. Antiepileptic drugs guideline for chronic pain

Antiepileptic drugs guideline for chronic pain Medical Treatment Guidelines Washington State Department of Labor and Industries Antiepileptic drugs guideline for chronic pain Purpose and development of the guideline The purpose of this guideline is to provide guidance to treating physicians in the use of Anti-Epileptic Drugs (AEDs) in the management of neuropathic pain. This guideline was developed by the Department of Labor and Industries and the Department of Social and Health Services Health (...) and Recovery Services in collaboration with expert opinion from actively practicing physicians who regularly treat chronic pain. The guideline is based on a systematic review of the current scientific literature regarding antiepileptic drugs in the treatment of chronic pain (neuropathic and somatic, musculoskeletal pain) and is limited to the following newer AEDs: gabapentin, lamotrigine (Lamictal), levetiracetam (Keppra), oxcarbazepine (Trileptal), tiagabine (Gabitril), topiramine (Topamax

Washington State Department of Labor and Industries2005

602. Both endurance training and strength training reduced disability and pain in chronic non-specific neck pain in women

Both endurance training and strength training reduced disability and pain in chronic non-specific neck pain in women Both endurance training and strength training reduced disability and pain in chronic non-specific neck pain in women | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Both endurance training and strength training reduced disability and pain in chronic non-specific neck pain in women Article Text Therapeutics Both endurance training and strength training reduced disability and pain in chronic non-specific neck pain in women Free Michael

Evidence-Based Medicine (Requires free registration)2004

603. Systematic review of topical capsaicin for the treatment of chronic pain

Systematic review of topical capsaicin for the treatment of chronic pain Systematic review of topical capsaicin for the treatment of chronic pain Systematic review of topical capsaicin for the treatment of chronic pain Mason L, Moore R A, Derry S, Edwards J E, McQuay H J CRD summary This review evaluated topically applied capsaicin for the treatment of chronic neuropathic and musculoskeletal pain. The authors concluded that capsaicin had a poor to moderate efficacy, but may be useful in people (...) unresponsive to, or intolerant of other treatments. Apparent differences across the included studies and the lack of an analysis of data for this subgroup suggest that the conclusions may not be reliable. Authors' objectives To determine the efficacy and safety of topically applied capsaicin for chronic pain from neuropathic or musculoskeletal disorders. Searching MEDLINE, PREMEDLINE, EMBASE, PubMed and the Cochrane Library were searched up to April 2003; the search strategy was provided. No language

DARE.2004

604. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain Mason L, Moore R A, Edwards J E, McQuay H J, Derry S, Wiffen P J CRD summary This review evaluated the efficacy and safety of topical (...) rubefacients in the treatment of acute and chronic pain. The authors concluded that topically applied rubefacient may be efficacious in the treatment of acute pain. However, they acknowledge that estimates for the efficacy of rubefacients are unreliable, owing to the lack of good clinical trials. Authors' objectives To determine the efficacy and safety of topical rubefacients containing salicylates in the treatment of acute and chronic pain. Searching MEDLINE, PREMEDLINE, EMBASE, PubMed and the Cochrane

DARE.2004

605. Gabapentin for non-malignant chronic pain

Gabapentin for non-malignant chronic pain Gabapentin for non-malignant chronic pain Gabapentin for non-malignant chronic pain Alberta Heritage Foundation for Medical Research Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Alberta Heritage Foundation for Medical Research. Gabapentin for non-malignant chronic pain. Edmonton: Alberta (...) Heritage Foundation for Medical Research (AHFMR). Technote TN 47. 2004 Authors' objectives

The aim of this report is to describe the background and the current evidence on the safety and efficacy/effectiveness of gabapentin when used in the management of non-malignant chronic pain.

Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Acetic Acids /therapeutic use; Analgesics /therapeutic use; Chronic Disease; Pain Language Published English Country of organisation Canada

Health Technology Assessment (HTA) Database.2004

606. Exercise and chronic low back pain: what works?

Exercise and chronic low back pain: what works? Exercise and chronic low back pain: what works? Exercise and chronic low back pain: what works? Liddle S D, Baxter G D, Gracey J H CRD summary This review investigated the type and quality of exercise interventions offered to patients with chronic low-back pain (CLBP). The authors concluded that exercise had a positive effect on CLBP patients, and these positive effects were generally well maintained at follow-up. The conclusions seem to follow (...) logically from the well-reported evidence; however, unpublished studies might have been missed. Authors' objectives To investigate the type and quality of exercise interventions offered to patients with chronic low-back pain (CLBP), and to identify characteristics essential to achieve and maintain successful results. Searching MEDLINE, CINAHL, ProQuest, PEDro, ISI Web of Science, the Cochrane CENTRAL Register and PubMed were searched from 1990 to 2002 for studies in English and other languages

DARE.2004

607. Opioids in chronic non-cancer pain: systematic review of efficacy and safety

Opioids in chronic non-cancer pain: systematic review of efficacy and safety Opioids in chronic non-cancer pain: systematic review of efficacy and safety Opioids in chronic non-cancer pain: systematic review of efficacy and safety Kalso E, Edwards J E, Moore R A, McQuay H J CRD summary This review assessed the efficacy and safety of opioids for chronic non-cancer pain. The authors concluded that opioids were effective for neuropathic and musculoskeletal pain in the short term (...) , but no conclusions could be drawn for tolerance or addiction. Although only high-quality randomised controlled trials were included, the review methods were not described in full and this weakens the strength of the evidence. Authors' objectives To assess the efficacy and safety of opioids in patients with chronic non-cancer pain. Searching The Oxford Pain Relief Database (1950 to 1994), MEDLINE (1966 to September 2003), EMBASE (1980 to September 2003) and the Cochrane Library (online, September 2003) were

DARE.2004

608. Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care

Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Mant J, McManus RJ, Oakes RA, Delaney BC, Barton PM, Deeks JJ, Hammersley L, Davies RC, Davies MK, Hobbs FD CRD summary This well-conducted review concluded (...) studies and relevant reviews were checked. Study selection Studies of patients with chest pain thought to be cardiac in origin who underwent a diagnostic test were eligible for inclusion. For patients with acute chest pain the following tests were eligible: history/clinical features as a test, resting electrocardiogram (ECG), or combinations of these. For patients with chronic chest pain studies, resting ECG and exercise ECG were eligible tests. Definitions of acute and chronic chest pain

DARE.2004

609. Biofeedback for headache and chronic musculoskeletal pain

Biofeedback for headache and chronic musculoskeletal pain Biofeedback for headache and chronic musculoskeletal pain Biofeedback for headache and chronic musculoskeletal pain Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Biofeedback for headache and chronic musculoskeletal pain. Lansdale: HAYES, Inc.. Directory Publication. 2004 Authors' objectives Biofeedback (...) is a behavioral training program that teaches a person how to control certain autonomic reactions such as heart rate, blood pressure, skin temperature, and muscular tension. The goal of biofeedback training for patients with chronic pain is to reduce or eliminate pain through learned control of physiological responses of the body. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Biofeedback (Psychology); Headache; Musculoskeletal Diseases; Pain

Health Technology Assessment (HTA) Database.2004

610. Spinal manipulation for chronic neck pain

Spinal manipulation for chronic neck pain Spinal manipulation for chronic neck pain Spinal manipulation for chronic neck pain Oduneye F Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Oduneye F. Spinal manipulation for chronic neck pain. London: Bazian Ltd (Editors), Wessex Institute for Health Research and Development, University of Southampton 2004: 10 Authors (...) ' objectives This study aims to assess the effectiveness of spinal manipulation on chronic neck pain. Authors' conclusions We found no randomised controlled trials comparing spinal manipulation with placebo or no treatment for chronic neck pain. We were, therefore, unable to draw conclusions about the effects of spinal manipulation relative to the natural progression of this condition. We found some evidence that spinal manipulation is equivalent to physiotherapy, intensive neck and shoulder training

Health Technology Assessment (HTA) Database.2004

611. Percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic low back pain

Percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic low back pain Percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic low back pain Percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic low back pain BlueCross BlueShield Association Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database (...) . The BlueCross BlueShield Association Technology Evaluation Center website ( ) includes the most recent 3 years of TEC Assessments. To request older reports, please use the “contact us” feature on the website. Citation BlueCross BlueShield Association. Percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic low back pain. Chicago: BlueCross BlueShield Association (BCBS). TEC Assessment 18(19). 2004 Authors' objectives This Assessment will review the available evidence to determine

Health Technology Assessment (HTA) Database.2004

612. Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care

Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Mant J, McManus R J, Oakes R A L, Delaney B C, Barton P M, Deeks J J, Hammersley L, Davies R C, Davies M K, Hobbs F D R Record Status This is a bibliographic (...) record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mant J, McManus R J, Oakes R A L, Delaney B C, Barton P M, Deeks J J, Hammersley L, Davies R C, Davies M K, Hobbs F D R. Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care. Health Technology Assessment 2004; 8(2): 1-170 Authors' objectives This review sought to answer

Health Technology Assessment (HTA) Database.2004

613. Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care

Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation

NIHR HTA programme2004

614. A practical guide to the provision of chronic pain services for adults in primary care

A practical guide to the provision of chronic pain services for adults in primary care A practical guide to the provision of Chronic Pain Services for adults in Primary Care This document has been produced by The British Pain Society and the Royal College of General Practitioners, supported by an educational grant from Napp Pharmaceuticals Limited. A practical guide to the provision of Chronic Pain Services for adults in Primary Care Date of production: October 2004 This document is supported (...) to the provision of Chronic Pain Services for adults in Primary Care A practical guide to the provision of Chronic Pain Services for adults in Primary Care Section 1 Introduction, foreword, acknowledgements and background information Section 2 Assessing the current status of pain management in your practice Section 3 Patient assessment Section 4 Aims and liaison in primary care Section 5 When to refer Appendix 1 Important documents Appendix 2 Courses in pain management Appendix 3 Useful definitions

Publication 10832004

615. Spinal cord stimulation for chronic pain.

Spinal cord stimulation for chronic pain. BACKGROUND: Spinal cord stimulation (SCS) is a form of therapy used to treat certain types of chronic pain. It involves an electrical generator that delivers pulses to a targeted spinal cord area. The leads can be implanted by laminectomy or percutaneously and the source of power is supplied by an implanted battery or by an external radio-frequency transmitter. The exact mechanism of action of SCS is poorly understood. OBJECTIVES: To assess the efficacy (...) randomized controlled trials (RCTs) or non-randomized controlled clinical trials (CCTs), that assessed spinal cord stimulation for chronic pain. DATA COLLECTION AND ANALYSIS: Two independent reviewers selected the studies, assessed study quality and extracted the data. One of the assessors of methodological quality was blinded to authors, dates and journals. The data were analysed using qualitative methods (best evidence synthesis). MAIN RESULTS: Two RCTs (81 patients in total) met our inclusion criteria

Cochrane2004

616. Prolotherapy injections for chronic low-back pain.

Prolotherapy injections for chronic low-back pain. BACKGROUND: Prolotherapy is an injection-based treatment for chronic low-back pain. Proponents of prolotherapy suggest that some back pain stems from weakened or damaged ligaments. Repeatedly injecting them with irritant solutions is believed to strengthen the ligaments and reduce pain and disability. Prolotherapy protocols usually include co-interventions to enhance the effectiveness of the injections. OBJECTIVES: To determine the efficacy (...) of prolotherapy injections in adults with chronic low-back pain. SEARCH STRATEGY: We searched CENTRAL (2004, issue 1), MEDLINE, EMBASE, CINAHL and Science Citation Index from their respective beginnings to January 2004, with no restrictions on language. We consulted content experts to ensure we had not missed any references. SELECTION CRITERIA: Randomised and quasi-randomised controlled trials comparing prolotherapy injections to control injections, either alone or in combination with other treatments, were

Cochrane2004

617. Chronic pain and poor self-rated health.

Chronic pain and poor self-rated health. CONTEXT: Chronic pain is common in Western societies. Self-rated health is an important indicator of morbidity and mortality, but little is known about the relation between chronic pain and self-rated health in the general population. OBJECTIVE: To analyze the association between chronic pain and self-rated health. DESIGN, SETTING, AND POPULATION: A questionnaire survey carried out during the spring of 2002 of an age- and sex-stratified population sample (...) of 6500 individuals in Finland aged 15 to 74 years, with a response rate of 71% (N = 4542) after exclusion of those with unobtainable data (n = 38). Chronic pain was defined as pain with a duration of at least 3 months and was graded by frequency: (1) at most once a week; (2) several times a week; and (3) daily or continuously. On the basis of a 5-item questionnaire on self-rated health, individuals were classified as having good, moderate, or poor health. Multinominal logistic regression analysis

JAMA2003

618. Patients with chronic pain and abnormal pituitary function require investigation.

Patients with chronic pain and abnormal pituitary function require investigation. Misuse of opioids is associated with abnormalities of pituitary function. Patients with chronic pain frequently complain of fatigue and undergo endocrine testing. To test whether oral opioid treatment causes abnormal pituitary function we prospectively assessed pituitary function in 37 patients with chronic pain who were receiving either oral opioid analgesia or non-opioid analgesia. Oral opioid treatment (...) was not associated with abnormal pituitary function although a few patients had abnormal results mainly related to obesity. Our results suggest that patients with chronic pain who have abnormal endocrine results should have a complete assessment, since abnormal test results cannot be attributed to their analgesia.

Lancet2003

619. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities.

Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. CONTEXT: Little is known about the prevalence and characteristics of chronic pain among patients with different types of chemical dependency. OBJECTIVES: To estimate the prevalence and to examine the characteristics of chronic severe pain in chemically dependent populations receiving methadone maintenance or inpatient residential treatment. DESIGN (...) , SETTING, AND PARTICIPANTS: Representative samples of 390 patients from 2 methadone maintenance treatment programs (MMTPs) and 531 patients from 13 short-term residential substance abuse treatment (inpatient) programs, all in New York State, were surveyed in late 2000 and early 2001. MAIN OUTCOME MEASURE: Prevalence of chronic severe pain, defined as pain that persisted for more than 6 months and was of moderate to severe intensity or that significantly interfered with daily activities. RESULTS

JAMA2003

620. Implantable spinal infusion devices for chronic pain and spasticity: an accelerated systematic review

Implantable spinal infusion devices for chronic pain and spasticity: an accelerated systematic review Implantable spinal infusion devices for chronic pain and spasticity: an accelerated systematic review Implantable spinal infusion devices for chronic pain and spasticity: an accelerated systematic review Simpson B, Middleton P, Maddern G CRD summary This review assessed the safety and efficacy of implantable spinal infusion devices to deliver opioids for the treatment of chronic pain (...) and baclofen for the treatment of spasticity. The authors concluded that spinal infusion devices appear safe and effective, though this was based on limited evidence. Given the weak evidence and methodological weaknesses in the review, the findings should be interpreted with caution. Authors' objectives To assess the safety and efficacy of implantable spinal infusion devices for treating chronic pain and spasticity. Searching MEDLINE, PREMEDLINE, EMBASE, Current Contents and PubMed were searched from

DARE.2003