Latest & greatest articles for chlorhexidine

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on chlorhexidine or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on chlorhexidine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for chlorhexidine

121. Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection.

Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health (...) Education * Associated Topics Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. Stacy Geisler DDS, PhD; Alexandra Jones BA, BCMB . Overview Systematic Review Conclusion Preoperative skin cleansing with chlorhexdine reduces surgical site infection by 32 percent as compared to povidone-iodine solution in clean-contaminated surgery. Critical Summary Assessment Strong evidence suggests that the use of topical chlorhexidine applied

2012 ADA Center for Evidence-Based Dentistry

122. Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection.

Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health (...) Education * Associated Topics Preoperative antisepsis with topical chlorhexidine in clean-contaminated surgery may reduce postoperative wound infection. Stacy Geisler DDS, PhD; Alexandra Jones BA, BCMB . Overview Systematic Review Conclusion Preoperative skin cleansing with chlorhexdine reduces surgical site infection by 32 percent as compared to povidone-iodine solution in clean-contaminated surgery. Critical Summary Assessment Strong evidence suggests that the use of topical chlorhexidine applied

2012 ADA Center for Evidence-Based Dentistry

123. The efficacy of daily bathing with chlorhexidine for reducing healthcare-associated bloodstream infections: a meta-analysis

The efficacy of daily bathing with chlorhexidine for reducing healthcare-associated bloodstream infections: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

124. Chlorhexidine gluconate (CHG) for suturing in the emergency room and perineal washing during vaginal deliveries: a review of safety, evidence-based guidelines and recommendations

Chlorhexidine gluconate (CHG) for suturing in the emergency room and perineal washing during vaginal deliveries: a review of safety, evidence-based guidelines and recommendations Chlorhexidine gluconate (CHG) for suturing in the emergency room and perineal washing during vaginal deliveries: a review of safety, evidence-based guidelines and recommendations Chlorhexidine gluconate (CHG) for suturing in the emergency room and perineal washing during vaginal deliveries: a review of safety, evidence (...) -based guidelines and recommendations CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Chlorhexidine gluconate (CHG) for suturing in the emergency room and perineal washing during vaginal deliveries: a review of safety, evidence-based guidelines and recommendations. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH

2012 Health Technology Assessment (HTA) Database.

125. 10% chlorhexidine varnish did not reduce caries in an adult population. (Abstract)

10% chlorhexidine varnish did not reduce caries in an adult population. A multi-centre, placebo-controlled, double-blind, randomised clinical trial involving 983 adults (aged 18-80 years old).The test group received chlorhexidine diacetate 10% weight per volume (w/v) dental coating and the control group received a placebo coating. Coatings were applied weekly for four weeks and a fifth time six months later.The Pitts and Fyffe taxonomy was used to measure caries progression or reversal, which (...) identifies three stages of lesion on coronal surfaces. The primary outcome was the total net increment in D(1-2)FS; secondary outcomes included the cumulative net D(1-2)FS increment and the total crude D(1-2)FS increment and the cumulative crude D(1-2)FS increment.No significant difference was seen between the treatment and placebo groups over a 13 month study period.Ten percent chlorhexidine diacetate coating did not show a reduction in caries in an adult population.

2012 Evidence-based dentistry Controlled trial quality: predicted high

126. Lower concentration of chlorhexidine and cetyl-pyridinium chloride mouthwash demonstrates some efficacy. Full Text available with Trip Pro

Lower concentration of chlorhexidine and cetyl-pyridinium chloride mouthwash demonstrates some efficacy. Randomised, parallel arm, double blind, placebo controlled trial.Forty-seven non-compliant patients with inadequate oral hygiene procedures were randomly allocated into test (22 patients) and placebo (25 patients) groups. The test group received a mouthrinse containing 0.05% CHX and 0.05% CPC as active ingredients. The placebo rinse was identical, except that it lacked the active

2012 Evidence-based dentistry Controlled trial quality: predicted high

127. Oral care with 0.12% chlorhexidine for the prevention of ventilator-associated pneumonia in critically ill children: Randomised, controlled and double blind trial (Abstract)

Oral care with 0.12% chlorhexidine for the prevention of ventilator-associated pneumonia in critically ill children: Randomised, controlled and double blind trial To test the effectiveness of oral care with 0.12% chlorhexidine in decreasing ventilator-associated pneumonia in critically ill children.Prospective, randomised, controlled, double-blind clinical trial performed in a paediatric critical care unit at a university hospital. The sample was composed of 96 mechanically ventilated children (...) randomly allocated to the chlorhexidine group (oral care with a toothbrush and an antiseptic gel twice a day) and the placebo group (oral care with a toothbrush and a non-antiseptic gel twice a day). Microbiological analyses of oropharyngeal and tracheal secretions were performed 24, 48 and 96h after intubation. Chi-square, Fischer's exact and Mann-Whitney tests were applied (p≤0.05).The chlorhexidine group was composed of 46 children, and the placebo group consisted of 50 children. Within

2012 EvidenceUpdates Controlled trial quality: predicted high

128. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis.

Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health (...) Education * Associated Topics Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Susan Parker RDH, B.S., MEd, MBA . Overview Systematic Review Conclusion For long-term use, essential oil mouthwash (EO-MW) appears to be a reliable alternative for chlorhexidine mouthwash (CHX-MW) with respect to parameters of gingival inflammation. Critical Summary Assessment In this relatively well-conducted systematic review, the authors were

2012 ADA Center for Evidence-Based Dentistry

129. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis.

Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health (...) Education * Associated Topics Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Susan Parker RDH, B.S., MEd, MBA . Overview Systematic Review Conclusion For long-term use, essential oil mouthwash (EO-MW) appears to be a reliable alternative for chlorhexidine mouthwash (CHX-MW) with respect to parameters of gingival inflammation. Critical Summary Assessment In this relatively well-conducted systematic review, the authors were

2012 ADA Center for Evidence-Based Dentistry

130. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis.

Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health (...) Education * Associated Topics Essential oil mouthwash, such as Listerine, may be reliable alternatives to chlorhexidine mouthwash in managing gingivitis. Susan Parker RDH, B.S., MEd, MBA . Overview Systematic Review Conclusion For long-term use, essential oil mouthwash (EO-MW) appears to be a reliable alternative for chlorhexidine mouthwash (CHX-MW) with respect to parameters of gingival inflammation. Critical Summary Assessment In this relatively well-conducted systematic review, the authors were

2012 ADA Center for Evidence-Based Dentistry

131. Chlorhexidine Gluconate (CHG) for Suturing in the Emergency Room and Perineal Washing During Vaginal Deliveries: A Review of Safety, Evidence-Based Guidelines and Recommendations

Chlorhexidine Gluconate (CHG) for Suturing in the Emergency Room and Perineal Washing During Vaginal Deliveries: A Review of Safety, Evidence-Based Guidelines and Recommendations Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources and a summary of the best evidence (...) be copied and used for non-commercial purposes, provided that attribution is given to CADTH. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Chlorhexidine Gluconate (CHG) for Suturing in the Emergency Room and Perineal Washing During Vaginal Deliveries: A Review of Safety, Evidence- Based

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

132. Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation

Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content (...) and certifying boards Evidence Education * Associated Topics Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Paul Hunter DMD, MLIS . Overview Systematic Review Conclusion A comparison of 0.12 percent to 0.2 percent chlorhexidine indicates that there is a small difference on plaque accumulation, no effect on gingivitis, and a lack of research for periodontal pocketing or attachment levels. Critical Summary Assessment

2012 ADA Center for Evidence-Based Dentistry

133. Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation

Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content (...) and certifying boards Evidence Education * Associated Topics Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Paul Hunter DMD, MLIS . Overview Systematic Review Conclusion A comparison of 0.12 percent to 0.2 percent chlorhexidine indicates that there is a small difference on plaque accumulation, no effect on gingivitis, and a lack of research for periodontal pocketing or attachment levels. Critical Summary Assessment

2012 ADA Center for Evidence-Based Dentistry

134. Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation

Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content (...) and certifying boards Evidence Education * Associated Topics Comparison of 0.12 percent to 0.2 percent chlorhexidine on periodontal health: limited clinical difference in effect on plaque accumulation Paul Hunter DMD, MLIS . Overview Systematic Review Conclusion A comparison of 0.12 percent to 0.2 percent chlorhexidine indicates that there is a small difference on plaque accumulation, no effect on gingivitis, and a lack of research for periodontal pocketing or attachment levels. Critical Summary Assessment

2012 ADA Center for Evidence-Based Dentistry

135. Clinically Significant Data to Prove Chlorhexidine Ineffective in Caries Prevention

Clinically Significant Data to Prove Chlorhexidine Ineffective in Caries Prevention UTCAT2236, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Clinically Significant Data to Prove Chlorhexidine Ineffective in Caries Prevention Clinical Question In an adult patient presenting with high caries risk, does chlorhexidine varnish or chlorhexidine rinse prevent new caries development when compared to placebo? Clinical Bottom (...) Line Chlorhexidine varnish and chlorhexidine rinse do not prevent the development of coronal caries in adults compared to placebo. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Papas/2012 983 adults, 20 intact teeth, 2 or more lesions at screening, mean age: 42, age range: 18-80 Randomized Controlled Trial Key results This clinical trial found no significant difference in new caries development

2012 UTHSCSA Dental School CAT Library

136. Chlorhexidine Gluconate versus Hydrogen Peroxide Oral Hygiene Rinse Preparations for the Prevention of Ventilator-Associated Pneumonia: Comparative Clinical Effectiveness and Safety

Chlorhexidine Gluconate versus Hydrogen Peroxide Oral Hygiene Rinse Preparations for the Prevention of Ventilator-Associated Pneumonia: Comparative Clinical Effectiveness and Safety Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic (...) by the owners’ own terms and conditions. TITLE: Chlorhexidine Gluconate versus Hydrogen Peroxide Oral Hygiene Rinse Preparations for the Prevention of Ventilator-Associated Pneumonia: Comparative Clinical Effectiveness and Safety DATE: 25 April 2012 RESEARCH QUESTIONS 1. What is the comparative clinical effectiveness of 0.12% chlorhexidine gluconate oral rinse solutions versus hydrogen peroxide oral rinse solutions for the prevention of ventilator-associated pneumonia? 2. What is the clinical evidence

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

137. Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing Study Full Text available with Trip Pro

Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing Study The randomized two-way factorial Dressing Study (1,636 patients, 28,931 catheter days) showed that a chlorhexidine-impregnated sponge decreased the incidence of major catheter-related infections from 1.4‰ to 0.6‰ catheter days, and that scheduled dressing changes every 7 days was not inferior to scheduled changes every 3 days. Here, we assessed (...) the cost benefits of chlorhexidine-impregnated sponge use.Costs directly related to major catheter-related infections and the costs of chlorhexidine-impregnated sponge and contact dermatitis were calculated prospectively using microcosting methods during the original study. The added length of stay in the intensive care unit due to major catheter-related infection was estimated using the disability model and assuming a cost of $2,118/intensive care unit day. The cost of each strategy was estimated

2012 EvidenceUpdates Controlled trial quality: uncertain

138. Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States

Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States Ye X, Rupnow M, Bastide P, Lafuma A, Ovington L, Jarvis WR Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to examine the clinical and economic impact, from a hospital perspective, of adding a chlorhexidine gluconate-impregnated sponge dressing to the standard care for the prevention of central-line

2012 NHS Economic Evaluation Database.

139. Chlorhexidine Rinse Treatment Improved Patients? Outcome When Combined With Scaling And Root Planning

Chlorhexidine Rinse Treatment Improved Patients? Outcome When Combined With Scaling And Root Planning UTCAT2266, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine Rinse Treatment Improved Patients’ Outcome When Combined With Scaling And Root Planning Clinical Question In adult periodontitis patients, will the use of Chlorhexidine rinse in conjunction with scaling and root planning be more effective than (...) scaling and root planning alone in reducing the pocket depths? Clinical Bottom Line Combining chlorhexidine rinse with scaling and root planning improves pocket depth more effectively than scaling and root planning alone. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Feres/2009 Sixty subjects from 30 to 55 years of age have untreated periodontal disease selected from clinical referral Randomized

2012 UTHSCSA Dental School CAT Library

140. Chlorhexidine cord cleansing to reduce neonatal mortality Full Text available with Trip Pro

Chlorhexidine cord cleansing to reduce neonatal mortality 22322125 2012 03 27 2018 12 01 1474-547X 379 9820 2012 Mar 17 Lancet (London, England) Lancet Chlorhexidine cord cleansing to reduce neonatal mortality. 984-6 10.1016/S0140-6736(12)60114-7 Osrin David D UCL Institute for Global Health, London, UK. d.osrin@ucl.ac.uk Hill Zelee Elizabeth ZE eng 091561 Wellcome Trust United Kingdom Journal Article Comment 2012 02 08 England Lancet 2985213R 0140-6736 0 Anti-Infective Agents, Local R4KO0DY52L (...) Chlorhexidine AIM IM Lancet. 2012 Mar 17;379(9820):1022-8 22322124 Lancet. 2012 Mar 17;379(9820):1029-36 22322126 Anti-Infective Agents, Local administration & dosage Bacterial Infections prevention & control Chlorhexidine administration & dosage Community Health Workers Female Humans Pregnancy Sepsis prevention & control Umbilical Cord microbiology UKMS47773 2012 2 11 6 0 2012 2 11 6 0 2012 3 28 6 0 ppublish 22322125 S0140-6736(12)60114-7 10.1016/S0140-6736(12)60114-7 PMC3428896 UKMS47773 J Health Popul

2012 Lancet