Latest & greatest articles for chlorhexidine

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Top results for chlorhexidine

81. Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness

Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness | CADTH.ca Find the information you need Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Chlorhexidine Gluconate Wipes (...) for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Published on: April 13, 2016 Project Number: RC0769-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of chlorhexidine gluconate wipes for infection prevention in adults patients in acute care? What is the clinical effectiveness of chlorhexidine gluconate wipes for infection prevention

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

82. A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation

A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation UTCAT3080, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation Clinical Question In patients undergoing implant placement (...) following ridge preservation, does the use of post operative antibiotics and chlorhexidine rinse increase the success rate of implant osseointegration compared to no antibiotic/chlorhexidine use? Clinical Bottom Line Both pre- and postoperative antibiotics and chlorhexidine use increase the success rate of implant osseointegration following bone graft placement. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence

2016 UTHSCSA Dental School CAT Library

83. Effect of digluconate chlorhexidine on bond strength between dental adhesive systems and dentin: A systematic review. (Full text)

Effect of digluconate chlorhexidine on bond strength between dental adhesive systems and dentin: A systematic review. This study aimed to systematically review the literature for the effect of digluconate chlorhexidine (CHX) on bond strength between dental adhesive systems and dentin of composite restorations.The electronic databases that were searched to identify manuscripts for inclusion were Medline via PubMed and Google search engine. The search strategies were computer search (...) of the database and review of reference lists of the related articles. Search words/terms were as follows: (digluconate chlorhexidine*) AND (dentin* OR adhesive system* OR bond strength*).Bond strength reduction after CHX treatments varied among the studies, ranging 0-84.9%. In most of the studies, pretreatment CHX exhibited lower bond strength reduction than the control experimental groups. Researchers who previously investigated the effect of CHX on the bond strength of dental adhesive systems on dentin

2016 Journal of conservative dentistry : JCD PubMed abstract

84. The Effect of Sodium Hypochlorite and Chlorhexidine as Irrigant Solutions for Root Canal Disinfection: A Systematic Review of Clinical Trials. (Full text)

The Effect of Sodium Hypochlorite and Chlorhexidine as Irrigant Solutions for Root Canal Disinfection: A Systematic Review of Clinical Trials. This systematic review aimed to compare the effectiveness of sodium hypochlorite and chlorhexidine for root canal disinfection during root canal therapy.A literature search for clinical trials was made on the PubMed (MEDLINE), Web of Knowledge, SCOPUS, and Science Direct databases and in the reference lists of the identified articles up to January 2015 (...) for both irrigants. Sodium hypochlorite was more effective than chlorhexidine in reducing microorganisms in 1 study, and another reported opposite findings. Both root irrigants were ineffective in eliminating endotoxins from necrotic pulp root canals in 1 study. Trial design and information regarding randomization procedures were not clearly described in the clinical trials. No study compared laboratory results with clinical outcomes.The available evidence on this topic is scarce, and the findings

2016 Journal of Endodontics PubMed abstract

85. Chlorhexidine Bathing and Health Care-Associated Infections: A Randomized Clinical Trial

Chlorhexidine Bathing and Health Care-Associated Infections: A Randomized Clinical Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2016 PedsCCM Evidence-Based Journal Club

86. Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper

Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper PS60 BP 2016 Page 1 PS60 BP 2016 Australian and New Zealand College of Anaesthetists (ANZCA) Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper 1. PURPOSE The purpose of PS60 Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine (...) is to prevent recurrent inadvertent exposure and subsequent hypersensitivity reaction in these patients. The ANZCA Anaesthetic Allergy Subcommittee was convened in 2012 and works closely with the Australian and New Zealand Anaesthetic Allergy Group (ANZAAG). The subcommittee identified that as chlorhexidine was a very common hidden agent in the theatre environment and it has an increasing frequency of induced anaphylaxis, it warranted a policy in its own right. PS60 has been developed as ‘Guidelines

2016 Australian and New Zealand College of Anaesthetists

87. Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine

Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine PS60 2016 Page 1 PS60 2016 Australian and New Zealand College of Anaesthetists (ANZCA) The following organisations have endorsed this document: Australian and New Zealand Anaesthetic Allergy Group (ANZAAG) Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Introduction 1.1 Chlorhexidine (1:6-Di-4 (...) and throat lozenges. 1.2 Recognition of the efficacy of chlorhexidine has seen its use dramatically increase within the hospital and community environments in recent years. Hypersensitivity to chlorhexidine has an unknown incidence, but is currently still rare. Concomitant with widespread use, however, there have been increasing reports of hypersensitivity to chlorhexidine, usually immediate type hypersensitivity (in its severe form, anaphylaxis). 1.3 Ready identification of all products containing

2016 Australian and New Zealand College of Anaesthetists

88. Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%)

Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Search Search Toggle navigation Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Back to guidelines homepage Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Published: 13/05/2016 Off-licence use of Hibitane (chlorhexidine 1%) has led to chemical burns when gauze swabs (...) soaked in the cream have been left in situ. The NHS England/ has been made aware of three separate incidents involving Hibitane (chlorhexidine 1%) cream which we are hereby drawing to your attention for local action. A few cases of chemical site burns with Hibitane (chlorhexidine 1%) occurring when Hibitane-soaked packs have been left in situ for several hours for gynaecological procedures have been reported to the MHRA and through the National Reporting and Learning System. Hibitane is licensed

2016 Royal College of Obstetricians and Gynaecologists

89. The effects of chlorhexidine gluconate bathing on health care-associated infection in intensive care units: A meta-analysis. (Abstract)

The effects of chlorhexidine gluconate bathing on health care-associated infection in intensive care units: A meta-analysis. The purpose was to assess the effects of chlorhexidine gluconate (CHG) bathing on health care-associated infections among critically ill patients.This meta-analysis evaluated English-language studies from the PubMed, Embase, and Cochrane databases. The Cochrane Collaboration methodology was used to evaluate all publications regarding daily CHG bathing and the risks

2015 Journal of critical care

90. Bathing With 2% Chlorhexidine Gluconate: Evidence and Costs Associated With Central Line-Associated Bloodstream Infections. (Abstract)

Bathing With 2% Chlorhexidine Gluconate: Evidence and Costs Associated With Central Line-Associated Bloodstream Infections. In a coordinated national effort reported by the Agency for Healthcare Research and Quality, the use of 2% chlorhexidine gluconate (CHG) has reduced the central line-associated bloodstream infection (CLABSI) rate by 40%. Conversely, a recent randomized clinical trial determined that chlorhexidine bathing did not reduce the CLABSI rate. The objectives of this study were

2015 Critical care nursing quarterly

91. Use of Chlorhexidine Prophylaxis in Preventing Oral Mucositis for Pediatric Cancer Patients

Use of Chlorhexidine Prophylaxis in Preventing Oral Mucositis for Pediatric Cancer Patients UTCAT2960, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Use of Chlorhexidine Prophylaxis in Preventing Oral Mucositis for Pediatric Cancer Patients Clinical Question Are pediatric cancer patients who received 0.12% chlorhexidine prophylaxis less likely to have oral mucositis? Clinical Bottom Line The effectiveness (...) of chlorhexidine prophylaxis in preventing oral mucositis for pediatric cancer patients has not been clearly supported by the literature. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Qutob/213 27 articles Systematic review of non-randomized studies Key results This paper systematically reviewed evidence on different agents used to prevent oral mucositis in children. Out of the 27 articles only seven reported

2015 UTHSCSA Dental School CAT Library

92. Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis. (Full text)

Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis. We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients.We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized controlled trials that compared daily bathing with chlorhexidine and a control in critically (...) ill patients.This meta-analysis included five RCTs. The overall incidence of measured hospital-acquired BSIs was significantly lower in the chlorhexidine group compared to the controls 0.69 (95 % CI 0.55-0.85; P < 0.001; I (2) = 57.7 %). Gram-positive-induced (RR = 0.49, 95 % CI 0.41-0.58; P = 0.000; I (2) = 0.0 %) bacteremias were significantly less common in the chlorhexidine group. The incidence of MRSA bacteremias (RR 0.63; 95 % CI 0.44-0.91; P = 0.006; I (2) = 30.3 %) was significantly lower

2015 Annals of intensive care PubMed abstract

93. The antimicrobial effect of chlorhexidine varnish on mutans streptococci in patients with fixed orthodontic appliances: a systematic review of clinical efficacy. (Abstract)

The antimicrobial effect of chlorhexidine varnish on mutans streptococci in patients with fixed orthodontic appliances: a systematic review of clinical efficacy. To conduct a systematic review aimed to determine the antimicrobial efficacy of chlorhexidine varnishes (CHX-V) on mutans streptococci (MS) in patients during orthodontic treatment with fixed appliances.A systematic computerized database search was conducted using Ovid MEDLINE, Scopus and EMBASE up to September 2014. A Google search

2015 International journal of dental hygiene

94. The Interaction of Sodium Hypochlorite and Chlorhexidine Gluconate, Two Commonly Used Endodontic Irrigants, Forms a Potentially Harmful Precipitate That Causes Obliteration of the Dentinal Tubules and Discoloration of the Root Canal System

The Interaction of Sodium Hypochlorite and Chlorhexidine Gluconate, Two Commonly Used Endodontic Irrigants, Forms a Potentially Harmful Precipitate That Causes Obliteration of the Dentinal Tubules and Discoloration of the Root Canal System UTCAT2907, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Interaction of Sodium Hypochlorite and Chlorhexidine Gluconate, Two Commonly Used Endodontic Irrigants, Forms (...) a Potentially Harmful Precipitate That Causes Obliteration of the Dentinal Tubules and Discoloration of the Root Canal System Clinical Question Does the interaction of sodium hypochlorite (NaOCl) and chlorhexidine gluconate (CHX) form a harmful precipitate in large enough amounts to cause patient concern? Clinical Bottom Line Sodium hypochlorite and chlorhexidine gluconate combine to form a dark brown precipitate containing small amounts of para-chloroanaline (PCA). PCA has been shown to be carcinogenic

2015 UTHSCSA Dental School CAT Library

95. Impact of daily bathing with chlorhexidine gluconate on ventilator associated pneumonia in intensive care units: a meta-analysis. (Full text)

Impact of daily bathing with chlorhexidine gluconate on ventilator associated pneumonia in intensive care units: a meta-analysis. Ventilator associated pneumonia (VAP) is the most important nosocomial infection in intensive care units (ICUs). Our objective was to assess whether daily bathing with chlorhexidine gluconate (CHG) would significantly result in the reduction of VAP.Meta-analysis of randomized controlled trials (RCTs) and quasi-experimental studies were conducted. The setting

2015 Journal of thoracic disease PubMed abstract

96. Chlorhexidine treatment for the prevention of dental caries in children and adolescents. (Abstract)

Chlorhexidine treatment for the prevention of dental caries in children and adolescents. Dental caries (tooth decay) is a common disease that is preventable by reducing the dietary intake of free sugars and using topical sodium fluoride products. An antibacterial agent known as chlorhexidine may also help prevent caries. A number of over-the-counter and professionally administered chlorhexidine-based preparations are available in a variety of formulations and in a range of strengths. Although (...) previous reviews have concluded that some formulations of chlorhexidine may be effective in inhibiting the progression of established caries in children, there is currently a lack of evidence to either claim or refute a benefit for its use in preventing dental caries.To assess the effects of chlorhexidine-containing oral products (toothpastes, mouthrinses, varnishes, gels, gums and sprays) on the prevention of dental caries in children and adolescents.We searched the Cochrane Oral Health Group Trials

2015 Cochrane

97. Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene

Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene UTCAT2890, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene Clinical Question In adults at high caries risk, is application of Chlorhexidine (...) varnish better than Fluoride varnish in reducing root caries incidence? Clinical Bottom Line Chlorhexidine-Thymol Varnish (CHX-V), when applied to high risk patients with poor oral hygiene, limits the incidence of root carries as well as reduces the rate of growth of existing lesions. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Slot/2011 574 adult patients in 6 included studies Meta-Analysis Key

2015 UTHSCSA Dental School CAT Library

98. No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries

No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries UTCAT2885, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries Clinical Question Is chlorhexidine mouthwash more effective in preventing caries development than chlorhexidine varnish? Clinical Bottom Line The available (...) clinical evidence supporting the efficacy of chlorhexidine varnish on preventing dental caries is weak. There is also no evidence to support the efficacy of chlorhexidine mouthwash in preventing dental caries. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Autio-Gold/2008 All age groups Literature review Key results A review of the current literature on chlorhexidine mouthwashes did not reveal

2015 UTHSCSA Dental School CAT Library

99. Chlorhexidine bathing and health care-associated infections: a randomized clinical trial. (Full text)

Chlorhexidine bathing and health care-associated infections: a randomized clinical trial. Daily bathing of critically ill patients with the broad-spectrum, topical antimicrobial agent chlorhexidine is widely performed and may reduce health care-associated infections.To determine if daily bathing of critically ill patients with chlorhexidine decreases the incidence of health care-associated infections.A pragmatic cluster randomized, crossover study of 9340 patients admitted to 5 adult intensive (...) care units of a tertiary medical center in Nashville, Tennessee, from July 2012 through July 2013.Units performed once-daily bathing of all patients with disposable cloths impregnated with 2% chlorhexidine or nonantimicrobial cloths as a control. Bathing treatments were performed for a 10-week period followed by a 2-week washout period during which patients were bathed with nonantimicrobial disposable cloths, before crossover to the alternate bathing treatment for 10 weeks. Each unit crossed over

2015 JAMA Controlled trial quality: predicted high PubMed abstract

100. Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection. (Full text)

Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection. Although early-onset group B β-hemolytic streptococcus (GBS) infection is rare, it accounts for approximately 30% of neonatal infections, has a high mortality rate, and is acquired through vertical transmission from colonized mothers. Several trials have demonstrated the efficacy of intrapartum antibiotic prophylaxis (IAP) for preventing early-onset disease (EOD). Vaginal disinfection (...) with chlorhexidine during labour has been proposed as another strategy for preventing GBS EOD in the preterm and term neonate. Chlorhexidine has been found to have no impact on antibiotic resistance, is inexpensive, and applicable to poorly equipped delivery sites.To determine the effectiveness of vaginal disinfection with chlorhexidine during labour in women who are colonized with GBS for preventing early-onset GBS infection in preterm and term neonates.We searched the Cochrane Pregnancy and Childbirth Group's

2015 Cochrane database of systematic reviews (Online) PubMed abstract