Latest & greatest articles for chlorhexidine

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on chlorhexidine or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on chlorhexidine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for chlorhexidine

41. Application of Chlorhexidine Varnish Decreases Incidence of Caries During Orthodontic Treatment

Application of Chlorhexidine Varnish Decreases Incidence of Caries During Orthodontic Treatment UTCAT3172, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Application of Chlorhexidine Varnish Decreases Incidence of Caries During Orthodontic Treatment Clinical Question In patients with fixed orthodontic appliances, does the professional application of chlorhexidine varnish decrease the incidence of caries during (...) orthodontic treatment? Clinical Bottom Line In patients with fixed orthodontic appliances, the professional application of chlorhexidine (CHX) varnish decreases the incidence of caries during orthodontic treatment. This is supported by a systematic review and meta-analysis of six studies, three split-mouth studies and three case control studies, which determined that caries was significantly lower with chlorhexidine application every 6-13 weeks during orthodontic treatment. Application of chlorhexidine

2017 UTHSCSA Dental School CAT Library

42. Strategies Utilizing Oil Pulling Are as Effective as Chlorhexidine Therapies for Maintaining Oral Hygiene

Strategies Utilizing Oil Pulling Are as Effective as Chlorhexidine Therapies for Maintaining Oral Hygiene UTCAT3226, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Strategies Utilizing Oil Pulling Are as Effective as Chlorhexidine Therapies for Maintaining Oral Hygiene Clinical Question For maintaining oral hygiene, are strategies utilizing oil pulling more effective than therapies utilizing chlorhexidine mouthrinse (...) ? Clinical Bottom Line Oil pulling and chlorhexidine (mouthwash or gel) therapies are equally effective in maintaining oral hygiene as demonstrated by their equal efficacy in reducing the bacteria counts, plaque and gingival indices scores. Thus oil pulling has the potential as a reliable method for routine oral hygiene measures. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Asokan/2009 20 age-matched

2017 UTHSCSA Dental School CAT Library

43. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Full Text available with Trip Pro

Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the gingivae to bleed easily. In susceptible individuals, gingivitis may lead to periodontitis and loss of the soft tissue and bony support for the tooth. It is thought (...) that chlorhexidine mouthrinse may reduce the build-up of plaque thereby reducing gingivitis.To assess the effectiveness of chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for the control of gingivitis and plaque compared to mechanical oral hygiene procedures alone or mechanical oral hygiene procedures plus placebo/control mouthrinse. Mechanical oral hygiene procedures were toothbrushing with/without the use of dental floss or interdental cleaning aids and could include

2017 Cochrane

44. Comparison of antimicrobial effects of titanium tetrafluoride, chlorhexidine, xylitol and sodium fluoride on streptococcus mutans: An in-vitro study Full Text available with Trip Pro

Comparison of antimicrobial effects of titanium tetrafluoride, chlorhexidine, xylitol and sodium fluoride on streptococcus mutans: An in-vitro study No studies have yet documented the bactericidal effects of TiF4, and its role in the treatment of dental caries, and no definite protocol has been introduced to regulate its use. The aim of this study was to determine the antimicrobial/bactericidal effects of TiF4 on Streptococcus Mutans (S. Mutans) and to compare it with chlorhexidine (Chx (...) , respectively. Xylitol failed to show any bactericidal or growth inhibitory effect in all of its concentrations. When we repeated the tests with an adjusted pH, identical results were obtained.TiF4 solutions have anti-growth and bactericidal effects on S. Mutans at a concentration of 12.5% which is comparable with chlorhexidine and NaF, indicating the possible use of this solution in dental practice as an anti-cariogenic agent, furthermore the antimicrobial activity is unaffected by pH of the environment.

2017 Electronic physician

45. Chlorhexidine Mouth Rinse Twice a Day Is at Least as Effective as Dental Floss in Reducing Plaque Buildup

Chlorhexidine Mouth Rinse Twice a Day Is at Least as Effective as Dental Floss in Reducing Plaque Buildup UTCAT3138, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine Mouth Rinse Twice a Day Is at Least as Effective as Dental Floss in Reducing Plaque Buildup Clinical Question In adult patients, does regular tooth brushing with adjunctive dental floss more effectively reduce plaque index as compared (...) to regular tooth brushing with adjunctive chlorhexidine mouth rinse? Clinical Bottom Line In adult patients, chlorhexidine mouth rinse is at least as effective as dental floss as an adjunct to regular tooth brushing in reducing plaque index. This is supported by two randomized control trials conducted in India, which showed that use of chlorhexidine mouth rinse resulted in clinically significant reductions in plaque indices as compared to dental floss. Prescription of chlorhexidine mouth rinse is within

2017 UTHSCSA Dental School CAT Library

46. Hydrogen Peroxide or Chlorhexidine Mouth Rinse After Scaling and Root Planing Are Equally Effective in Improving Clinical Attachment and Gingival Inflammation Levels in Adult Patients with Chronic Periodontitis

Hydrogen Peroxide or Chlorhexidine Mouth Rinse After Scaling and Root Planing Are Equally Effective in Improving Clinical Attachment and Gingival Inflammation Levels in Adult Patients with Chronic Periodontitis UTCAT3147, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Hydrogen Peroxide or Chlorhexidine Mouth Rinse After Scaling and Root Planing Are Equally Effective in Improving Clinical Attachment and Gingival (...) Inflammation Levels in Adult Patients with Chronic Periodontitis Clinical Question In an adult patient with chronic periodontitis, is home use of hydrogen peroxide rinse as an adjunct to scaling and root planing more effective in improving clinical attachment level than chlorhexidine home rinse after scaling and root planing? Clinical Bottom Line Neither a 10-day course of hydrogen peroxide mouth rinse or chlorhexidine mouth rinse after scaling and root planing yielded significant improvements in clinical

2017 UTHSCSA Dental School CAT Library

47. Evaluation of the anticariogenic activity of Cervitec® (1% chlorhexidine and 1% thymol) varnish versus fluoride-containing products: a systematic review and meta-analysis

Evaluation of the anticariogenic activity of Cervitec® (1% chlorhexidine and 1% thymol) varnish versus fluoride-containing products: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2017 PROSPERO

48. Comparative effectiveness of Chlorhexidine Gluconate as an antiseptic skin solution for reducing central venous or arterial catheter-related infections: a systematic review and network meta-analysis

Comparative effectiveness of Chlorhexidine Gluconate as an antiseptic skin solution for reducing central venous or arterial catheter-related infections: a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external

2017 PROSPERO

49. Chlorhexidine (CHX) May Improve Bond Longevity and Reduce Failure of Resin Composites

Chlorhexidine (CHX) May Improve Bond Longevity and Reduce Failure of Resin Composites UTCAT3128, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine (CHX) May Improve Bond Longevity and Reduce Failure of Resin Composites Clinical Question Does pretreatment with chlorhexidine (CHX) improve bond longevity in patients with composite restorations? Clinical Bottom Line Pretreatment with chlorhexidine does improve (...) the microtensile strength of the bond in resin composites, but more studies are needed to determine if the results are clinically significant and if CHX extends the life of the restoration. Pretreatment with chlorhexidine has been found to be potentially deleterious only in self-etching adhesive systems. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Dionysopoulos/2016 14 studies that used CHX as pre-treatment

2017 UTHSCSA Dental School CAT Library

50. Can chlorhexidine as a cavity cleaning agent influence the adhesion of restorative materials? A systematic review and meta-analysis

Can chlorhexidine as a cavity cleaning agent influence the adhesion of restorative materials? A systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2017 PROSPERO

51. The comparative efficacy of chlorhexidine in reducing bloodstream infections when accessing peripheral intravenous ports

The comparative efficacy of chlorhexidine in reducing bloodstream infections when accessing peripheral intravenous ports Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence

2017 PROSPERO

52. Effect of Chlorhexidine Bathing Every Other Day on Prevention of Hospital-Acquired Infections in the Surgical ICU: A Single-Center, Randomized Controlled Trial (Abstract)

Effect of Chlorhexidine Bathing Every Other Day on Prevention of Hospital-Acquired Infections in the Surgical ICU: A Single-Center, Randomized Controlled Trial To test the hypothesis that compared with daily soap and water bathing, 2% chlorhexidine gluconate bathing every other day for up to 28 days decreases the risk of hospital-acquired catheter-associated urinary tract infection, ventilator-associated pneumonia, incisional surgical site infection, and primary bloodstream infection (...) in surgical ICU patients.This was a single-center, pragmatic, randomized trial. Patients and clinicians were aware of treatment-group assignment; investigators who determined outcomes were blinded.Twenty-four-bed surgical ICU at a quaternary academic medical center.Adults admitted to the surgical ICU from July 2012 to May 2013 with an anticipated surgical ICU stay for 48 hours or more were included.Patients were randomized to bathing with 2% chlorhexidine every other day alternating with soap and water

2016 EvidenceUpdates Controlled trial quality: predicted high

53. A Randomized, Clinical Trial of Preadmission Chlorhexidine Skin Preparation Following Lower Extremity Total Joint Arthroplasty (Abstract)

A Randomized, Clinical Trial of Preadmission Chlorhexidine Skin Preparation Following Lower Extremity Total Joint Arthroplasty Periprosthetic infections are devastating postoperative complications of total joint arthroplasty (TJA), with native skin flora commonly identified as causative organisms. We compared 2% chlorhexidine gluconate-impregnated cloths to standard-of-care antiseptic bathing in patients before TJA, to evaluate periprosthetic infection risk at 1-year follow-up.This (...) was a prospective, randomized, controlled trial at a single institution of patients undergoing hip or knee arthroplasty. Chlorhexidine-treated patients (275 arthroplasties) applied 2% chlorhexidine gluconate-impregnated cloths the night before and morning of admission. The standard-of-care cohort (279 arthroplasties) bathed with soap and water preadmission. Patients were excluded according to the following: (1) unable to comply with study requirements, (2) pregnant, (3) <18 years, (4) medical history

2016 EvidenceUpdates Controlled trial quality: uncertain

54. In-hospital patient bathing with 2% chlorhexidine gluconate cloths (Sage Products Inc.) for prevention of hospital-acquired infections

In-hospital patient bathing with 2% chlorhexidine gluconate cloths (Sage Products Inc.) for prevention of hospital-acquired infections In-hospital patient bathing with 2% chlorhexidine gluconate cloths (Sage Products Inc.) for prevention of hospital-acquired infections In-hospital patient bathing with 2% chlorhexidine gluconate cloths (Sage Products Inc.) for prevention of hospital-acquired infections HAYES, Inc. Record Status This is a bibliographic record of a published health technology (...) assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. In-hospital patient bathing with 2% chlorhexidine gluconate cloths (Sage Products Inc.) for prevention of hospital-acquired infections. Lansdale: HAYES, Inc.. Directory Publication. 2016 Authors' conclusions Purpose of Technology: The purpose of bathing hospitalized patients with cloths impregnated with the antiseptic 2% chlorhexidine gluconate (CHG) is, as part of a comprehensive

2016 Health Technology Assessment (HTA) Database.

55. Effectiveness of Decolonization With Chlorhexidine and Mupirocin in Reducing Surgical Site Infections: A Systematic Review. (Abstract)

Effectiveness of Decolonization With Chlorhexidine and Mupirocin in Reducing Surgical Site Infections: A Systematic Review. Surgical site infections (SSI) are a serious complication of surgery. Staphylococcus aureus (S aureus) is 1 of the most common causative organisms responsible for SSI. Patients who are carriers of methicillin-resistant S aureus and methicillin-sensitive S aureus are at increased risk of developing S aureus-associated SSIs. Decolonization of skin with chlorhexidine (...) and nares with mupirocin may reduce the risk of SSI.The primary object of this systematic review is to examine the effectiveness of preoperative universal decolonization of skin with chlorhexidine and nares with intranasal mupirocin in preventing SSIs.The following databases were searched: Ovid Medline (from 1946 to September week 3, 2015), Embase (1947 to 2015, week 38), EBSCO CINHAL (1980-2015), Cochrane Collaboration for Systematic Reviews, EBM Reviews, and Google Scholar.All experimental

2016 Dimensions of critical care nursing : DCCN

56. Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness

Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness | CADTH.ca Find the information you need Chlorhexidine Gluconate Wipes for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Chlorhexidine Gluconate Wipes (...) for Infection Prevention in Acute and Critical Care: A Review of Clinical Effectiveness and Cost-Effectiveness Published on: April 13, 2016 Project Number: RC0769-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of chlorhexidine gluconate wipes for infection prevention in adults patients in acute care? What is the clinical effectiveness of chlorhexidine gluconate wipes for infection prevention

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

57. A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation

A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation UTCAT3080, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title A Regimen of Postoperative Antibiotics and Chlorhexidine Rinses Can Increase The Success Rate of Implant Osseointegration Following Ridge Preservation Clinical Question In patients undergoing implant placement (...) following ridge preservation, does the use of post operative antibiotics and chlorhexidine rinse increase the success rate of implant osseointegration compared to no antibiotic/chlorhexidine use? Clinical Bottom Line Both pre- and postoperative antibiotics and chlorhexidine use increase the success rate of implant osseointegration following bone graft placement. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence

2016 UTHSCSA Dental School CAT Library

58. Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine

Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine PS60 2016 Page 1 PS60 2016 Australian and New Zealand College of Anaesthetists (ANZCA) The following organisations have endorsed this document: Australian and New Zealand Anaesthetic Allergy Group (ANZAAG) Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Introduction 1.1 Chlorhexidine (1:6-Di-4 (...) and throat lozenges. 1.2 Recognition of the efficacy of chlorhexidine has seen its use dramatically increase within the hospital and community environments in recent years. Hypersensitivity to chlorhexidine has an unknown incidence, but is currently still rare. Concomitant with widespread use, however, there have been increasing reports of hypersensitivity to chlorhexidine, usually immediate type hypersensitivity (in its severe form, anaphylaxis). 1.3 Ready identification of all products containing

2016 Australian and New Zealand College of Anaesthetists

59. Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper

Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper PS60 BP 2016 Page 1 PS60 BP 2016 Australian and New Zealand College of Anaesthetists (ANZCA) Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine Background Paper 1. PURPOSE The purpose of PS60 Guidelines on the Perioperative Management of Patients with Suspected or Proven Hypersensitivity to Chlorhexidine (...) is to prevent recurrent inadvertent exposure and subsequent hypersensitivity reaction in these patients. The ANZCA Anaesthetic Allergy Subcommittee was convened in 2012 and works closely with the Australian and New Zealand Anaesthetic Allergy Group (ANZAAG). The subcommittee identified that as chlorhexidine was a very common hidden agent in the theatre environment and it has an increasing frequency of induced anaphylaxis, it warranted a policy in its own right. PS60 has been developed as ‘Guidelines

2016 Australian and New Zealand College of Anaesthetists

60. Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%)

Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Search Search Toggle navigation Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Back to guidelines homepage Potential for harm as a result of off-licence use of Hibitane (chlorhexidine 1%) Published: 13/05/2016 Off-licence use of Hibitane (chlorhexidine 1%) has led to chemical burns when gauze swabs (...) soaked in the cream have been left in situ. The NHS England/ has been made aware of three separate incidents involving Hibitane (chlorhexidine 1%) cream which we are hereby drawing to your attention for local action. A few cases of chemical site burns with Hibitane (chlorhexidine 1%) occurring when Hibitane-soaked packs have been left in situ for several hours for gynaecological procedures have been reported to the MHRA and through the National Reporting and Learning System. Hibitane is licensed

2016 Royal College of Obstetricians and Gynaecologists