Latest & greatest articles for chlorhexidine

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Top results for chlorhexidine

21. Chlorhexidine-impregnated dressing for the prophylaxis of central venous catheter-related complications: a systematic review and meta-analysis. (Full text)

Chlorhexidine-impregnated dressing for the prophylaxis of central venous catheter-related complications: a systematic review and meta-analysis. Several randomized controlled trials (RCTs) evaluated the role of Chlorhexidine-impregnated dressing for prophylaxis of central venous catheter (CVC) related complications, but the results remained inconsistent, updated meta-analyses on this issue are warranted.A meta-analysis on the RCTs comparing Chlorhexidine-impregnated dressing versus other (...) bias.A total of 12 RCTs with 6028 patients were included. The Chlorhexidine-impregnated dressings provided significant benefits in reducing the risk of catheter colonization (OR = 0.46, 95% CI: 0.36 to 0.58), decreasing the incidence of catheter-related bloodstream infection (CRBSI) (OR = 0.60, 95% CI: 0.42 to 0.85). Subgroup analysis indicated that the Chlorhexidine-impregnated dressings were conducive to reduce the risk of catheter colonization and CRBSI within the included RCTs with sample size

2019 BMC Infectious Diseases PubMed abstract

22. The impact of chlorhexidine bathing on hospital-acquired bloodstream infections: a systematic review and meta-analysis. (Full text)

The impact of chlorhexidine bathing on hospital-acquired bloodstream infections: a systematic review and meta-analysis. Chlorhexidine gluconate (CHG) bathing of hospitalized patients may have benefit in reducing hospital-acquired bloodstream infections (HABSIs). However, the magnitude of effect, implementation fidelity, and patient-centered outcomes are unclear. In this meta-analysis, we examined the effect of CHG bathing on prevention of HABSIs and assessed fidelity to implementation

2019 BMC Infectious Diseases PubMed abstract

23. Endotoxin levels after chemomechanical preparation of root canals with sodium hypochlorite or chlorhexidine: a systematic review of clinical trials and meta-analysis. (Full text)

Endotoxin levels after chemomechanical preparation of root canals with sodium hypochlorite or chlorhexidine: a systematic review of clinical trials and meta-analysis. The aim of this systematic review was to answer the following question: in patients with primary endodontic infection, is there a statistically significant difference in the endotoxin levels after chemomechanical preparation with sodium hypochlorite (NaOCl) or chlorhexidine (CHX)?A protocol was prepared and registered on PROSPERO

2019 International endodontic journal PubMed abstract

24. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic review and meta-analysis. (Full text)

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic review and meta-analysis. The plant Salvadora persica (miswak) has a long history of use in oral hygiene. Associations between the use of Salvadora persica and decreased oral bacteria numbers and plaque scores have been reported. This systematic review and meta-analysis assessed the ability of Salvadora persica mouthrinses to reduce plaque/cariogenic bacteria (...) , in comparison to that of chlorhexidine and/or placebo rinses.A comprehensive literature search for clinical trials reporting the use of Salvadora persica rinses as an antibacterial and/or antiplaque agent in comparison with chlorhexidine and/or placebo rinses was conducted, with no restriction to language. MEDLINE-PubMed, Cochrane Central Register of Controlled Trials, Wiley Online Library, ScienceDirect, and Google Scholar databases were searched to include all articles published up to December 2018. Based

2019 BMC Oral Health PubMed abstract

25. Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial. (Abstract)

Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial. Universal skin and nasal decolonisation reduces multidrug-resistant pathogens and bloodstream infections in intensive care units. The effect of universal decolonisation on pathogens and infections in non-critical-care units is unknown. The aim of the ABATE Infection trial was to evaluate (...) the use of chlorhexidine bathing in non-critical-care units, with an intervention similar to one that was found to reduce multidrug-resistant organisms and bacteraemia in intensive care units.The ABATE Infection (active bathing to eliminate infection) trial was a cluster-randomised trial of 53 hospitals comparing routine bathing to decolonisation with universal chlorhexidine and targeted nasal mupirocin in non-critical-care units. The trial was done in hospitals affiliated with HCA Healthcare

2019 Lancet Controlled trial quality: predicted high

26. Effectiveness of daily chlorhexidine bathing for reducing gram-negative infections: A meta-analysis. (Abstract)

Effectiveness of daily chlorhexidine bathing for reducing gram-negative infections: A meta-analysis. Multiple studies have demonstrated that daily chlorhexidine gluconate (CHG) bathing is associated with a significant reduction in infections caused by gram-positive pathogens. However, there are limited data on the effectiveness of daily CHG bathing on gram-negative infections. The aim of this study was to determine whether daily CHG bathing is effective in reducing the rate of gram-negative

2019 Infection control and hospital epidemiology

27. Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysis. (Abstract)

Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysis. Postoperative pneumonia is one of the most common complications after cardiac surgery, entailing increased patient morbidity, mortality, and health care burden. The primary aim of this study was to assess whether preoperative chlorhexidine mouthwash is associated with reduced postoperative pneumonia after cardiac surgery.A comprehensive systematic search of NLM Pubmed, Embase (...) , Scopus, and Cumulative Index of Nursing and Allied Health was executed to include the studies since inception to June 27, 2017, which assessed the effects of preoperative chlorhexidine gluconate mouthwash on postoperative pneumonia. Studies were identified by 2 independent reviewers, and data were extracted using a predefined protocol. Random effects models were run to obtain risk ratios with 95% confidence intervals. Quality of evidence was evaluated using Grading of Recommendations Assessment

2019 Journal of Thoracic and Cardiovascular Surgery

28. Evidence for the effectiveness of chlorhexidine bathing and health care-associated infections among adult intensive care patients: a trial sequential meta-analysis. (Full text)

Evidence for the effectiveness of chlorhexidine bathing and health care-associated infections among adult intensive care patients: a trial sequential meta-analysis. Health care associated infections (HAI) among adults admitted to the intensive care unit (ICU) have been shown to increase length of stay, the cost of care, and in some cases increased the risk of hospital death (Kaye et al., J Am Geriatr Soc 62:306-11, 2014; Roberts et al., Med Care 48:1026-35, 2010; Warren et al., Crit Care Med 34 (...) :2084-9, 2006; Zimlichman et al., JAMA Intern Med 173:2039-46, 2013). Daily bathing with chlorhexidine gluconate (CHG) has been shown to decrease the risk of infection in the ICU (Loveday et al., J Hosp Infect 86:S1-S70, 2014). However, due to varying quality of published studies, and varying estimates of effectiveness, CHG bathing is not universally practiced. As a result, current opinion of the merit of CHG bathing to reduce hospital acquired infections in the ICU, is divergent, suggesting a state

2018 BMC Infectious Diseases PubMed abstract

29. Triple Antibiotic Solution Promotes Similar Antibacterial Effects as Calcium Hydroxide/2% Chlorhexidine When Used as an Intracanal Medicament

Triple Antibiotic Solution Promotes Similar Antibacterial Effects as Calcium Hydroxide/2% Chlorhexidine When Used as an Intracanal Medicament UTCAT3361, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Triple Antibiotic Solution Promotes Similar Antibacterial Effects as Calcium Hydroxide/2% Chlorhexidine When Used as an Intracanal Medicament Clinical Question In patients undergoing non-surgical therapy in a tooth (...) diagnosed with pulpal necrosis, does the use of triple antibiotic paste as an intracanal medicament have better antibacterial efficacy than a calcium hydroxide/chlorhexidine formulation? Clinical Bottom Line Triple antibiotic solution (1 mg/mL) promoted similar antibacterial effects as calcium hydroxide/2% chlorhexidine when used as an intracanal medicament. This is based on several randomized clinical trials in which intracanal medicaments were placed for 7 to 21 days in primary and immature/mature

2018 UTHSCSA Dental School CAT Library

30. Adjunctive Use of Chlorhexidine Mouthwash to Nonsurgical Periodontal Therapy May Enhance Periodontal Pocket Depth Reduction. (Abstract)

Adjunctive Use of Chlorhexidine Mouthwash to Nonsurgical Periodontal Therapy May Enhance Periodontal Pocket Depth Reduction. Chlorhexidine mouthwash as an adjunct to mechanical therapy in chronic periodontitis: a meta-analysis. da Costa L, Amaral C, Barbirato D, Leao A, Fogacci M.JADA 2017;148(5):308-18.The authors' own institutions.A meta-analysis.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 Journal of Evidence Based Dental Practice

31. [ANZEN]Revisions of PRECAUTIONS: Medical Devices Containing Chlorhexidine Gluconate or Chlorhexidine Hydrochloride posted

[ANZEN]Revisions of PRECAUTIONS: Medical Devices Containing Chlorhexidine Gluconate or Chlorhexidine Hydrochloride posted Revisions of PRECAUTIONS | Pharmaceuticals and Medical Devices Agency Please make JavaScript on and see this site. Navigation of each product type Our recommended contents Navigation of each product type Our recommended contents Revisions of PRECAUTIONS Here begins the text. Revisions of PRECAUTIONS PRECAUTIONS in package inserts include information such as Warning (...) holders consequently revise PRECAUTIONS according to the notice. Posted date Device name Detailed information on revisions of PRECAUTIONS (from MHLW) Summary of investigation results (from PMDA) November 13, 2018 August 8, 2018 (Originally Posted in Japanese) Ultrasonic Surgical Aspirator Devices November 30, 2017 November 2, 2017 (Originally Posted in Japanese) Medical Devices Containing Chlorhexidine Gluconate or Chlorhexidine Hydrochloride not applicable July 26, 2016 July 25, 2016 (Originally

2018 Pharmaceuticals and Medical Devices Agency, Japan

32. Antiseptic efficacies of waterless hand rub, chlorhexidine scrub, and povidone-iodine scrub in surgical settings: a meta-analysis of randomized controlled trials. (Abstract)

Antiseptic efficacies of waterless hand rub, chlorhexidine scrub, and povidone-iodine scrub in surgical settings: a meta-analysis of randomized controlled trials. Presurgical hand washing is crucial for preventing surgical site infections (SSIs). Chlorhexidine gluconate (CHG) and povidone-iodine (PI) products have been conventionally used as hand scrubs for presurgical hand preparation. However, waterless hand rub (WHR) products have been developed for operating room staff.The aim of this study

2018 Journal of Hospital Infection

33. Chlorhexidine-based body washing for colonization and infection of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus: an updated meta-analysis (Full text)

Chlorhexidine-based body washing for colonization and infection of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus: an updated meta-analysis The effects of chlorhexidine-based body washing (CHW) on health care-associated infections have been reported in numerous studies, while their findings remain conflicting. This study aims to update the evidence for the effects of CHW on the risk of colonization or infection with hospital-acquired methicillin-resistant

2018 Infection and drug resistance PubMed abstract

34. Chlorhexidine

Chlorhexidine Top results for chlorhexidine - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for chlorhexidine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

35. What is the result of vaginal cleansing with chlorhexidine during labour on maternal and neonatal infections? A systematic review of randomised trials with meta-analysis. (Full text)

What is the result of vaginal cleansing with chlorhexidine during labour on maternal and neonatal infections? A systematic review of randomised trials with meta-analysis. Infection with vaginal microorganisms during labour can lead to maternal and neonatal mortality and morbidity. The objective of this systematic review is to review the effectiveness of intrapartum vaginal chlorhexidine in the reduction of maternal and neonatal colonisation and infectious morbidity.Search strategy - Eight (...) vaginal chlorhexidine interventions. Meta-analysis found no significant differences between the intervention and control groups for any of the four outcomes: maternal or neonatal colonization or infection. The preferred method for chlorhexidine administration was vaginal irrigation.Meta-analysis did not demonstrate improved maternal or neonatal outcomes with intrapartum vaginal chlorhexidine cleansing, however this may be due to the limitations of the available studies. A larger, multicentre

2018 BMC Pregnancy and Childbirth PubMed abstract

36. Chlorhexidine gel to prevent alveolar osteitis following mandibular third molar extractions. (Full text)

Chlorhexidine gel to prevent alveolar osteitis following mandibular third molar extractions. Data sourcesMedline/PubMed, Cochrane central, Scopus and Google scholar.Study selectionRandomised controlled trials (RCTs) published in English between January 2010 and December 2015 were identified by two reviewers. Unpublished studies were not considered.Data extraction and synthesisStandard Cochrane Collaboration assessment tools were used to carry out a risk of bias assessment. The following data (...) were collected from the articles; sample size, country, mean age of participants, diagnosis of alveolar osteitis (AO), type of intervention and outcomes. Heterogeneity (I2) was calculated to determine the statistical model to be used for meta-analysis.ResultsTen randomised control trials (RCTs) were included, with 862 participants. Eight studies used 0.2% chlorhexidine (CHX) gel in the experimental group, 1% CHX gel in one study, and in one study the concentration was not specified. Two studies

2018 Evidence Based Dentistry PubMed abstract

37. Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis

Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made (...) for the HTA database. Citation HAYES, Inc. Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Rationale: Skin preparation products are used prior to surgery to quickly eliminate a wide range of microbes and provide a continuously high level of antimicrobial action for an extended duration of time. Technology Description: Skin preparation products are used prior to surgery to quickly

2018 Health Technology Assessment (HTA) Database.

38. Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics?

Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics? 1 Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics? Technical Report Prepared for National Health and Medical Research Council (NHMRC) Submitted by University of South Australia Division of Health Sciences Submission date 24th April 2017 2 Contents Page 1. Review Team and Background…………………………..…………………………….….3 2. Methods (...) The National Health and Medical Research Council (NHMRC) commissioned this independent literature review to provide assurance that the revision of the Australian Guidelines for the Prevention and Control of Infection in Healthcare (2010 Guidelines) is grounded in the most up-to-date and relevant scientific evidence. 4 Methods Literature review The clinical questions were: 1. Does exposure (different dosages, duration of use, and stratification of exposure) to any form of chlorhexidine result

2018 National Health and Medical Research Council

39. Does chlorhexidine reduce bacteremia following tooth extraction? A systematic review and meta-analysis. (Full text)

Does chlorhexidine reduce bacteremia following tooth extraction? A systematic review and meta-analysis. Scientific evidence is not clear regarding the use of antimicrobial mouth rinse before dental extraction to reduce bacteremia. We tested the null hypothesis that there would be no difference in the incidence of bacteremia following dental extractions in patients treated with or without chlorhexidine.We conducted a meta-analysis following the recommendations proposed by PRISMA Preferred (...) Reporting Items for Systematic Reviews and Meta-Analyses. The data sources Pubmed, Cochrane, Web of Science, Science Direct, Scopus, and Ovid MD were searched until April 30, 2017. (chlorhexidine) AND (bacteremia OR bacteraemia) AND (extraction OR removal) were used as key words in a free-text search. Published meeting abstracts were searched. The references of each article were reviewed. We only included randomized controlled clinical trials. There were no restrictions regarding language or date

2018 PLoS ONE PubMed abstract

40. A randomized open-label controlled trial of chlorhexidine-alcohol vs povidone-iodine for cesarean antisepsis: the CAPICA trial (Abstract)

A randomized open-label controlled trial of chlorhexidine-alcohol vs povidone-iodine for cesarean antisepsis: the CAPICA trial Identification of optimal surgical site antisepsis preparations may reduce cesarean-related surgical site infections. Two recently published investigations examined efficacy of chlorhexidine-alcohol and iodine-alcohol preparations. No previous randomized controlled trial has compared chlorhexidine-alcohol to povidone-iodine aqueous scrub and paint in reduction (...) of cesarean-related surgical site infection.The purpose of the study was to determine if chlorhexidine-alcohol would result in fewer surgical site infections than povidone-iodine when used as skin antisepsis preparation prior to cesarean delivery.This study was a single-center pragmatic randomized controlled trial at an urban tertiary care institution to compare chlorhexidine-alcohol 26-mL single-step applicator to povidone-iodine aqueous scrub and paint 236-mL wet skin tray as preoperative skin

2017 EvidenceUpdates