Latest & greatest articles for chlorhexidine

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Top results for chlorhexidine

1. Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis. (Full text)

Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis. Background and Objectives: The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times. Materials and Methods: A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up (...) to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups. Results: Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI

2020 Medicina (Kaunas, Lithuania) PubMed abstract

2. Does chlorhexidine mouthwash, with an anti-discoloration system, reduce tooth surface discoloration without losing its efficacy? A systematic review and meta-analysis. (Full text)

Does chlorhexidine mouthwash, with an anti-discoloration system, reduce tooth surface discoloration without losing its efficacy? A systematic review and meta-analysis. To investigate whether chlorhexidine mouthwash (CHX-MW), with an anti-discoloration system(ADS), is effective in preventing extrinsic tooth surface discoloration. Additionally, this paper seeks to evaluate whether CHX combined with an ADS maintains its efficacy with respect to reducing plaque and gingivitis scores.MEDLINE-PubMed

2020 International journal of dental hygiene PubMed abstract

3. Chlorhexidine-Alcohol Compared with Povidone-Iodine Preoperative Skin Antisepsis for Cesarean Delivery: A Systematic Review and Meta-Analysis. (Abstract)

Chlorhexidine-Alcohol Compared with Povidone-Iodine Preoperative Skin Antisepsis for Cesarean Delivery: A Systematic Review and Meta-Analysis. To compare chlorhexidine-alcohol with povidone-iodine solutions for skin antisepsis prior to cesarean delivery for the prevention of surgical site infection.Electronic databases MEDLINE, Embase, Scopus, and Clinicaltrials.gov were searched from inception to August 2017. Eligible studies included randomized controlled trials comparing chlorhexidine (...) . The risk of surgical site infection was significantly reduced with chlorhexidine-alcohol (RR: 0.72; 95% CI: 0.52-0.98). No heterogeneity across studies was observed with I2 = 0%. Subgroup analysis of superficial infection only or deep infection only showed no statistically significant difference (RR: 0.76, 95% CI: 0.54-1.08; and RR: 0.50, 95% CI: 0.23-1.10, respectively).Preoperative skin cleansing prior to cesarean delivery with chlorhexidine-alcohol reduces surgical site infection as compared

2020 American journal of perinatology

4. Preoperative Antisepsis with Chlorhexidine Versus Povidone-Iodine for the Prevention of Surgical Site Infection: a Systematic Review and Meta-analysis. (Full text)

Preoperative Antisepsis with Chlorhexidine Versus Povidone-Iodine for the Prevention of Surgical Site Infection: a Systematic Review and Meta-analysis. Chlorhexidine (CH) and povidone-iodine (PI) are the most commonly used preoperative skin antiseptics at present. However, the prevention of the surgical site infection (SSI) and the incidence of skin adverse events do not reach a consistent statement and conclusion. This meta-analysis aimed to evaluate the efficacy of chlorhexidine and povidone (...) . This study revealed that chlorhexidine was superior to povidone-iodine in the prevention of postoperative SSI (risk ratio [RR], 0.65; 95% confidence interval [CI], 0.55-0.77; p < 0.00001, I2 = 57%). Further subgroup analysis showed that chlorhexidine was superior to povidone-iodine in the prevention of postoperative SSI in clean surgery (risk ratio [RR], 0.81; 95% confidence interval [CI], 0.67-0.98; p = 0.03), I2 = 28%) and clean-contaminated surgery (risk ratio [RR], 0.58; 95% confidence interval [CI

2020 World Journal of Surgery PubMed abstract

5. Chlorhexidine disinfectant can reduce the risk of central venous catheter infection compared with povidone: a meta-analysis. (Abstract)

Chlorhexidine disinfectant can reduce the risk of central venous catheter infection compared with povidone: a meta-analysis. Assess the efficacy of chlorhexidine with povidone solutions as a skin disinfectant for central venous catheter (CVC) care.Central venous catheters are widely used for critically ill patients. Catheter maintenance can easily lead to a catheter-related bloodstream infection (CRBSI), which is the manifestation of a bloodstream infection (BSI) in a patient who carries (...) a catheter or removes the catheter within 48 hours. There is no clear source of BSIs except for indwelling catheters in the blood vessels, and BSIs significantly increase the morbidity and mortality of patients. We assess the efficacy of chlorhexidine with povidone as a skin disinfectant for CVC care.In July 2018, we searched the Cochrane Library, PubMed, EMBASE, Web of Science, OVID, CNKI, SinoMed, WanFangData, CqVip, and DuXiu for publications in English and Chinese. By searching articles published

2020 American journal of infection control

6. Chlorhexidine-Related Mortality Rate in Critically Ill Subjects in Intensive Care Units: A Systematic Review and Meta-Analysis. (Full text)

Chlorhexidine-Related Mortality Rate in Critically Ill Subjects in Intensive Care Units: A Systematic Review and Meta-Analysis. This meta-analysis aimed to explore the chlorhexidine-related mortality rate for subjects on mechanical ventilation and in an ICU when compared with subjects who received standard ICU care.We searched a number of medical literature databases and the first 100 results in an internet search. Two of us independently reviewed the titles and abstracts of the identified (...) participants were critically ill adults in ICU settings of high-income countries (n = 1157) and low/ middle-income countries (n = 612). They were assigned to either the chlorhexidine or control groups. Overall, moderate-quality evidence indicated reduced ventilator-associated pneumonia incidence (for high-income countries: RR 0.60, 95% CI 0.41-0.87; P = .008; I2 = 39%; and for low- and middle-income countries: RR 0.71, 95% CI 0.51-0.99; P = .05; I2 = 10%), without a substantial effect on mortality rate

2020 Respiratory care PubMed abstract

7. Sequential use of povidone-iodine and chlorhexidine for cutaneous antisepsis: A systematic review. (Abstract)

Sequential use of povidone-iodine and chlorhexidine for cutaneous antisepsis: A systematic review. Cutaneous antisepsis with chlorhexidine or povidone-iodine, usually with alcohol, has been extensively studied. This review of published studies reveals that sequential use of povidone-iodine and chlorhexidine leads to a greater reduction in the bioburden of aerobic and anaerobic bacteria on the skin, lower risk of intravascular catheter colonization, and lower risk of surgical site infection

2020 Infection control and hospital epidemiology

8. Effect of chlorhexidine cord application on prevention of neonatal sepsis in developing countries: Systematic review and meta-analysis. (Abstract)

Effect of chlorhexidine cord application on prevention of neonatal sepsis in developing countries: Systematic review and meta-analysis. The aim of this review was to identify the pooled effect of chlorhexidine cord application on prevention of neonatal sepsis in developing countries.We have conducted systemic review and meta-analysis. Articles were searched from electronic databases such as PubMed, EMBASE, CINHAL, Cochrane central register of controlled trials (CENTRAL), and other sources (...) such as direct Google search, Google Scholar, and POPline. Only randomized controlled trial studies were considered for this review. The effect of chlorhexidine cord application on prevention of neonatal sepsis and mortality was assessed as compared to dry cord care.Five studies from developing countries were included in the review with a total of 129,293 participants. Pooled result of meta-analysis showed that chlorhexidine cord application reduces neonatal sepsis by 32% as compared to dry cord care

2020 International journal of health sciences

9. Chlorhexidine Gel Use in the Oral District: A Systematic Review. (Full text)

Chlorhexidine Gel Use in the Oral District: A Systematic Review. Chlorhexidine compounds and their different formulations have been investigated several times, especially in the dentistry field. Chlorhexidine application for mouth rinsing immediately underwent oral contraindications, linked to the possibility of causing pigmentation to the teeth or relating to possible cytotoxic events after oral surgery. The positive effects, however, are considerable and its topical antiseptic action has been (...) widely demonstrated by in vitro and clinical research. That's the reason for its large application in different fields of dentistry. The aim of this study is to collect all the literature regarding the use of chlorhexidine gel in dentistry and all the numerous applications. The initial search on search engines obtained 232 results; then, following the application of the inclusion criteria there were 24 selected articles. The chlorhexidine gel appliance in the dental daily practice is direct to oral

2020 Gels (Basel, Switzerland) PubMed abstract

10. The Effects of Chlorhexidine Dressing on Health Care-Associated Infection in Hospitalized Patients: A Meta-Analysis. (Abstract)

The Effects of Chlorhexidine Dressing on Health Care-Associated Infection in Hospitalized Patients: A Meta-Analysis. To assess the effects of chlorhexidine dressing on health care-associated infection in hospitalized patients.We searched for English-language published randomized controlled trials (RCTs) in Cochrane Library, EMBASE and PubMed between January 1998 and January 2018. We used meta-analysis to calculate the risk ratios (RRs) and 95% confidence intervals (CIs) of the data, and using (...) the I2 assessment to summarize the heterogeneity of RCTs and the funnel plot and Egger regression test to evaluate publication bias.A total of 13 RCTs were included in our meta-analysis, including 7555 patients and 11,931 catheters. The effects of chlorhexidine dressing on the incidence of catheter-related bloodstream infections (CRBSIs) were reported in 13 RCTs, and the incidence of CRBSIs were 1.3% (80/6160) in the chlorhexidine group and 2.5% (145/5771) in the control group. We used a forest plot

2020 Iranian journal of public health

11. Efficacy of chlorhexidine rinses after periodontal or implant surgery: a systematic review. (Full text)

Efficacy of chlorhexidine rinses after periodontal or implant surgery: a systematic review. Biofilm management and infection control are essential after periodontal and implant surgery. In this context, chlorhexidine (CHX) mouth-rinses are frequently recommended post-surgically. Despite its common use and many studies in this field, a systematic evaluation of the benefits after periodontal or implant surgery is-surprisingly-still missing.To evaluate the benefits of chlorhexidine rinsing after

2020 Clinical oral investigations PubMed abstract

12. Adjunctive subgingival application of Chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis: a systematic review and meta-analysis. (Full text)

Adjunctive subgingival application of Chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis: a systematic review and meta-analysis. Subgingival applications of chlorhexidine (CHX) gel are commonly used as an adjunct in nonsurgical periodontal treatment (NSPT) for chronic periodontitis (CP). However, there is lack of systematic review and meta-analysis justifying the effects of adjunctive CHX gel on clinical outcomes. The objective of this meta-analysis was to evaluate

2020 BMC oral health PubMed abstract

13. Efficacy of aloe vera mouthwash versus chlorhexidine on plaque and gingivitis: A systematic review. (Abstract)

Efficacy of aloe vera mouthwash versus chlorhexidine on plaque and gingivitis: A systematic review. The present systematic review assessed the efficacy of aloe vera mouthrinse on plaque and gingival inflammation.A comprehensive search of PubMed, EMBASE, Scopus and Web of Science was conducted in February 2018 to identify all relevant studies using the following keywords: aloe vera, gingivitis, gingival inflammation, plaque-induced gingivitis, periodontal health and plaque control (...) . The eligibility criteria were all randomized clinical trials that assessed the efficacy of aloe vera mouthrinse in comparison to chlorhexidine on plaque and gingivitis. The risk of bias of the included studies was assessed using the Cochrane risk of bias assessment tool.Six randomized clinical trials comprising 1358 subjects were included in this systematic review. All included studies showed that aloe vera was effective in reducing plaque and gingival inflammation. Four studies found aloe vera as effective

2020 International journal of dental hygiene

14. Application of 4% chlorhexidine to the umbilical cord stump of newborn infants in lower income countries: a systematic review and meta-analysis. (Full text)

Application of 4% chlorhexidine to the umbilical cord stump of newborn infants in lower income countries: a systematic review and meta-analysis. There are conflicting results from large randomized controlled trials in different populations regarding the effectiveness of topical application of 4% chlorhexidine to the umbilical stump of newborn infants at reducing neonatal mortality. Meta-analysis and systematic review of trials performed in South Asia and Europe support 4% chlorhexidine (...) application to reduce neonatal mortality, whereas trials performed in Sub-Saharan Africa do not. The aim of this review is to determine the effectiveness of 4% chlorhexidine application to the umbilical stump of newborn infants born in lower income countries in order to reduce neonatal mortality when compared with usual cord care.Our search strategy included randomized trials published between January1st 2000 and September 4th, 2018, that compared 4% chlorhexidine with usual cord care ("dry cord care

2019 Maternal health, neonatology and perinatology PubMed abstract

15. Chlorhexidine for Oral Care: A Review of Clinical Effectiveness and Guidelines

Chlorhexidine for Oral Care: A Review of Clinical Effectiveness and Guidelines Chlorhexidine for Oral Care: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Chlorhexidine for Oral Care: A Review of Clinical Effectiveness and Guidelines Chlorhexidine for Oral Care: A Review of Clinical Effectiveness and Guidelines Last updated: January 25, 2019 Project Number: RC1064-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical (...) Appraisal Result type: Report Question What is the clinical effectiveness of Chlorhexidine for oral care in hospitalized adults? What are the evidence-based guidelines regarding the use of Chlorhexidine for oral care in hospitalized adults? Key Message Chlorhexidine oral care was effective for the prevention of nosocomial pneumonia (NP), ventilator-associated pneumonia (VAP) and bloodstream infection among adult populations in cardiothoracic intensive care units (ICUs), but evidence is unclear

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

16. Chlorhexidine Gluconate for Skin Preparation During Stereotactic Core Biopsy of the Breast: Clinical Effectiveness and Guidelines

Chlorhexidine Gluconate for Skin Preparation During Stereotactic Core Biopsy of the Breast: Clinical Effectiveness and Guidelines Chlorhexidine Gluconate for Skin Preparation During Stereotactic Core Biopsy of the Breast: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Chlorhexidine Gluconate for Skin Preparation During Stereotactic Core Biopsy of the Breast: Clinical Effectiveness and Guidelines Chlorhexidine Gluconate for Skin Preparation During Stereotactic (...) Core Biopsy of the Breast: Clinical Effectiveness and Guidelines Last updated: February 8, 2019 Project Number: RB1309-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of chlorhexidine gluconate wipes for female adults undergoing skin preparation during stereotactic core biopsy of the breast? What are the evidence-based guidelines associated with skin preparation during stereotactic core biopsy

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

17. Chlorhexidine Gluconate for Skin Preparation during Minor Procedures: Clinical Effectiveness and Guidelines

Chlorhexidine Gluconate for Skin Preparation during Minor Procedures: Clinical Effectiveness and Guidelines Chlorhexidine Gluconate for Skin Preparation during Minor Procedures: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Chlorhexidine Gluconate for Skin Preparation during Minor Procedures: Clinical Effectiveness and Guidelines Chlorhexidine Gluconate for Skin Preparation during Minor Procedures: Clinical Effectiveness and Guidelines Last updated: June 3, 2019 (...) Project Number: RB1346-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of chlorhexidine gluconate wipes for adults undergoing skin preparation for minor procedures? What are the evidence-based guidelines associated with skin preparation during minor procedures? Key Message Two systematic reviews with meta-analyses, one systematic review, one non-randomized trial, and three evidence-based guidelines

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

18. Chlorhexidine bathing of the critically ill for the prevention of hospital-acquired infection. (Abstract)

Chlorhexidine bathing of the critically ill for the prevention of hospital-acquired infection. Hospital-acquired infection is a frequent adverse event in patient care; it can lead to longer stays in the intensive care unit (ICU), additional medical complications, permanent disability or death. Whilst all hospital-based patients are susceptible to infections, prevalence is particularly high in the ICU, where people who are critically ill have suppressed immunity and are subject to increased (...) invasive monitoring. People who are mechanically-ventilated are at infection risk due to tracheostomy and reintubation and use of multiple central venous catheters, where lines and tubes may act as vectors for the transmission of bacteria and may increase bloodstream infections and ventilator-associated pneumonia (VAP). Chlorhexidine is a low-cost product, widely used as a disinfectant and antiseptic, which may be used to bathe people who are critically ill with the aim of killing bacteria and reducing

2019 Cochrane

19. Effect of chlorhexidine bathing on colonization or infection with Acinetobacter baumannii: a systematic review and meta-analysis. (Abstract)

Effect of chlorhexidine bathing on colonization or infection with Acinetobacter baumannii: a systematic review and meta-analysis. Healthcare-associated infections (HAIs) caused by multi-drug-resistant Gram-negative bacteria (MDRGNB) have increased prevalence in intensive care units (ICUs). A common strategy to prevent HAIs is bathing patients with chlorhexidine gluconate (CHG). However, the effectiveness of CHG bathing against multidrug-resistant Acinetobacter baumannii (MDRAB) is still (...) : 0.57-0.77; P<0.001). Chlorhexidine at 4% showed a better effect than 2% chlorhexidine (meta-regression P=0.044). CHG bathing was associated with a non-significant reduction of infection (pooled RR 0.41, 95% CI: 0.13-1.25). This study suggests that CHG bathing significantly reduces colonization of A. baumannii in the ICU setting. However, more trials are needed to confirm whether CHG bathing can reduce infections with A. baumannii.Copyright © 2019 The Healthcare Infection Society. Published

2019 Journal of Hospital Infection

20. Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery: A Systematic Review. (Abstract)

Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery: A Systematic Review. The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery.The PRISMA guideline was adopted in the search strategy using electronic databases PubMed and MEDLINE to identify randomized and case-control (...) prospective studies on humans written in English language and published up to September 2017.A total of 10 articles were selected for a total of 344 patients. Because of the significant heterogeneity of the outcome measures, meta-analysis was not performed, and the data were summarized in a table. A positive relationship between the use of chlorhexidine and reduction of plaque was found, demonstrating the effectiveness of the substance in terms of antisepsis and decrease of inflammation after periodontal

2019 Implant dentistry