Latest & greatest articles for children

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Top results for children

161. Specialist-led improvised music therapy did not improve children’s symptoms of autism

Specialist-led improvised music therapy did not improve children’s symptoms of autism Signal - Specialist-led improvised music therapy did not improve children’s symptoms of autism Dissemination Centre Discover Portal NIHR DC Discover Specialist-led improvised music therapy did not improve children’s symptoms of autism Published on 28 November 2017 After five months, improvised music therapy added to enhanced usual care was no better than enhanced usual care alone for young children (...) with an autism spectrum disorder (ASD). Clinically meaningful improvements in social and communication skills were not achieved in either group over this time. This result from a large well designed NIHR-funded international trial contrasts with an earlier systematic review of small trials that suggested beneficial effects for this specialised therapy. Qualified music therapists provided social interactions with the children through music and singing once to three times per week. Centres in nine countries

NIHR Dissemination Centre2018

162. Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study

Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study 30116548 2018 11 14 2055-0936 4 2018 Tropical diseases, travel medicine and vaccines Trop Dis Travel Med Vaccines Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study. 8 10.1186/s40794-018-0069-1 According to the Ethiopian national malaria indicator survey of 2015 (...) , the highest burden of Plasmodia infection resided among the school-age children. Even though several studies revealed various determinant factors of childhood malaria, consistent findings are not reported across the nation and elsewhere. This in turn creates obstacles in implementing exactprevention and control measures in the study area in particular and the country at large. The aim of this study is to determine the incidence of Plasmodium and determinant factors among febrile children in Northwest

Tropical diseases, travel medicine and vaccines2018 Full Text: Link to full Text with Trip Pro

163. Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial)

Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial) 30097463 2018 11 14 2473-9537 2 15 2018 Aug 14 Blood advances Blood Adv Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial). 1969-1979 10.1182/bloodadvances.2018021444 Blood cell membranes in sickle cell disease (SCD) have low docosahexaenoic acid (DHA). DHA treatment reduces sickle cell crisis (SCC) rate and ameliorates (...) the inflammation, oxidative stress, and hypercoagulable state of SCD. SC411 is a novel DHA ethyl ester formulation with a proprietary delivery platform (Advanced Lipid Technology) that enhances DHA bioavailability. The SCOT trial investigated the effect of 3 different doses of SC411 on clinical and biochemical endpoints in 67 children with SCD (5-17 years old). Seventy-six percent of subjects were also receiving hydroxyurea. After 4 weeks of treatment with SC411 at 20, 36, and 60 mg DHA/kg per day or placebo

Blood advances2018 Full Text: Link to full Text with Trip Pro

164. Needle size for vaccination procedures in children and adolescents.

Needle size for vaccination procedures in children and adolescents. BACKGROUND: This is an update of a Cochrane Review first published in 2015. The conclusions have not changed.Hypodermic needles of different sizes (gauges and lengths) can be used for vaccination procedures. The gauge (G) refers to the outside diameter of the needle tubing. The higher the gauge number, the smaller the diameter of the needle (e.g. a 23 G needle is 0.6 mm in diameter, whereas a 25 G needle is 0.5 mm in diameter (...) ). Many vaccines are recommended for injection into muscle (intramuscularly), although some are delivered subcutaneously (under the skin) and intradermally (into skin). Choosing an appropriate length and gauge of a needle may be important to ensure that a vaccine is delivered to the appropriate site and produces the maximum immune response while causing the least possible harm. Guidelines conflict regarding the sizes of needles that should be used for vaccinating children and adolescents. OBJECTIVES

Cochrane2018

165. Schools can provide valuable help for children with attention deficit hyperactivity disorder

Schools can provide valuable help for children with attention deficit hyperactivity disorder Signal - Schools can provide valuable help for children with attention deficit hyperactivity disorder Dissemination Centre Discover Portal NIHR DC Discover Schools can provide valuable help for children with attention deficit hyperactivity disorder Published on 14 September 2015 This series of NIHR-funded systematic reviews found that some things schools do (interventions) can help children (...) with attention deficit hyperactivity disorder. These were grouped into 15 main approaches including reward and punishment, skills training and self-management, creative-based therapies, such as music therapy, and structured physical activity. These reviews covered different strategies to change behaviour other than giving children medication. Most showed positive effects. Due to substantial variation in the effect on symptoms, behaviour or educational achievement across the included studies, the reviews were not able to specify the best

NIHR Dissemination Centre2018

166. Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in Body Mass Index: A Randomized Clinical Trial.

Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in Body Mass Index: A Randomized Clinical Trial. Importance: Prevention of obesity during childhood is critical for children in underserved populations, for whom obesity prevalence and risk of chronic disease are highest. Objective: To test the effect of a multicomponent behavioral intervention on child body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) growth (...) trajectories over 36 months among preschool-age children at risk for obesity. Design, Setting, and Participants: A randomized clinical trial assigned 610 parent-child pairs from underserved communities in Nashville, Tennessee, to a 36-month intervention targeting health behaviors or a school-readiness control. Eligible children were between ages 3 and 5 years and at risk for obesity but not yet obese. Enrollment occurred from August 2012 to May 2014; 36-month follow-up occurred from October 2015 to June

JAMA2018

167. Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study

Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study 30450464 2018 12 07 2468-0249 3 6 2018 Nov Kidney international reports Kidney Int Rep Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study. 1373-1384 10.1016/j.ekir.2018.07.021 The Cure Glomerulonephropathy Network (CureGN) is a 66-center longitudinal observational (...) study of patients with biopsy-confirmed minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, or IgA nephropathy (IgAN), including IgA vasculitis (IgAV). This study describes the clinical characteristics and treatment patterns in the IgA cohort, including comparisons between IgAN versus IgAV and adult versus pediatric patients. Patients with a diagnostic kidney biopsy within 5 years of screening were eligible to join CureGN. This is a descriptive analysis of clinical

Kidney international reports2018 Full Text: Link to full Text with Trip Pro

168. Safety and Side Effects of Rifampin versus Isoniazid in Children.

Safety and Side Effects of Rifampin versus Isoniazid in Children. BACKGROUND: The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life-threatening forms of tuberculosis disease. The current standard treatment - 9 months of isoniazid - has been associated with poor adherence and toxic effects, which have hampered the effectiveness of the drug. In adults, treatment with 4 months of rifampin has been shown to be safer (...) and to have higher completion rates than 9 months of isoniazid. METHODS: In this multicenter, open-label trial, we randomly assigned 844 children (<18 years of age) with latent M. tuberculosis infection to receive either 4 months of rifampin or 9 months of isoniazid. The primary outcome was adverse events of grade 1 to 5 that resulted in the permanent discontinuation of a trial drug. Secondary outcomes were treatment adherence, side-effect profile, and efficacy. Independent review panels whose members

NEJM2018

169. Chronic Cough Related to Acute Viral Bronchiolitis in Children

Chronic Cough Related to Acute Viral Bronchiolitis in Children Chronic Cough Related to Acute Viral Bronchiolitis in Children CHEST Expert Panel Report Anne B. Chang, MBBS, PhD, MPH; John J. Oppenheimer, MD; Bruce K. Rubin, MD; Miles Weinberger, MD, FCCP; and Richard S. Irwin, MD, Master FCCP; on behalf of the CHEST Expert Cough Panel BACKGROUND: Acute bronchiolitis is common in young children, and some children develop chronic cough after their bronchiolitis. We thus undertook systematic (...) reviews based on key questions (KQs) using the PICO (Population, Intervention, Comparison, Outcome) format. The KQs were: Among children with chronic cough (> 4 weeks) after acute viral bron- chiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta 2 agonist, montelukast); and (3) Inhaled osmotic agents like hypertonic saline? METHODS: We used the CHEST expert cough

American College of Chest Physicians2018

170. Molecular Karyotyping in Children and Adolescents with Gender Dysphoria

Molecular Karyotyping in Children and Adolescents with Gender Dysphoria 30094339 2018 11 14 2380-193X 3 1 2018 Transgender health Transgend Health Molecular Karyotyping in Children and Adolescents with Gender Dysphoria. 147-153 10.1089/trgh.2017.0051 Purpose: The presence of a disorder of sexual development (DSD) acts as a diagnostic specifier for gender dysphoria (GD) under DSM-5, while the International Classification of Diseases (ICD)-10 specifically states that its equivalent diagnosis (...) , gender identity disorder (GID), must not be the result of a chromosomal abnormality. For these reasons, routine karyotyping has been previously advocated in the clinical work-up of children and adolescents with suspected GD or GID. However, the utility of such testing remains unclear. Methods: The results of routine molecular karyotyping were analyzed in 128 patients attending our Australian statewide pediatric gender service from 2013 to 2016. Karyotyping was performed using an Illumina BeadChip

Transgender health2018 Full Text: Link to full Text with Trip Pro

171. Temporal and regional trends of choking injuries in children in Italy, 2001–2013

Temporal and regional trends of choking injuries in children in Italy, 2001–2013 30066094 2018 11 14 2197-1714 5 1 2018 Aug 01 Injury epidemiology Inj Epidemiol Temporal and regional trends of choking injuries in children in Italy, 2001-2013. 30 10.1186/s40621-018-0160-0 Choking injuries in children are a significant public health problem. The present study was aimed at examining the epidemiologic patterns of choking injuries in children using Italian official data from hospital discharge (...) records. Hospital discharge records (from 2001 to 2013) reporting cases of choking injuries corresponding to the ICD-9 CM codes 933 ("Foreign body in pharynx and larynx"), 934 ("Foreign body in trachea, bronchus, and lung"), and fourth digit specifications (933.0 "pharynx", 933.1 "larynx", 934.0 "trachea", 934.1 "main bronchus", 934.8 "other specified parts", 934.9 "respiratory tree, unspecified") occurred in children aged 0-14 years were analyzed to assess the temporal and regional trends. Annual

Injury epidemiology2018 Full Text: Link to full Text with Trip Pro

172. A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes

A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes 29873107 2018 06 19 1464-5491 2018 Jun 05 Diabetic medicine : a journal of the British Diabetic Association Diabet. Med. A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes. 10.1111/dme.13703 To compare systematically the impact of two novel insulin-dosing algorithms (the Pankowska Equation and the Food Insulin (...) Index) with carbohydrate counting on postprandial glucose excursions following a high fat and a high protein meal. A randomized, crossover trial at two Paediatric Diabetes centres was conducted. On each day, participants consumed a high protein or high fat meal with similar carbohydrate amounts. Insulin was delivered according to carbohydrate counting, the Pankowska Equation or the Food Insulin Index. Subjects fasted for 5 h following the test meal and physical activity was standardized

EvidenceUpdates2018

173. Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department

Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department 29986857 2018 07 17 1488-2329 190 27 2018 Jul 09 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department. E816-E822 10.1503/cmaj.170406 (...) There is uncertainty about which children with minor head injury need to undergo computed tomography (CT). We sought to prospectively validate the accuracy and potential for refinement of a previously derived decision rule, Canadian Assessment of Tomography for Childhood Head injury (CATCH), to guide CT use in children with minor head injury. This multicentre cohort study in 9 Canadian pediatric emergency departments prospectively enrolled children with blunt head trauma presenting with a Glasgow Coma Scale score

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

174. Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study

Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study 29998359 2018 07 12 1496-8975 2018 Jul 11 Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study. 10.1007/s12630-018-1183-2 Gastric (...) insufflation is common during face mask ventilation and results in unfavourable respiratory events in children. The purpose of this study was to evaluate the effect of a muscle relaxant on gastric insufflation and determine the optimal inspiratory pressure during face mask ventilation in children. Children aged one month to five years were randomly assigned to neuromuscular blocker (NM) or non-neuromuscular blocker (non-NM) groups. After administering intravenous anesthetics, face mask ventilation

EvidenceUpdates2018

175. Children

Children Top results for children - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for children The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

Trip Latest and Greatest2018

176. Gynecologic Issues in Children and Adolescent Cancer Patients and Survivors

Gynecologic Issues in Children and Adolescent Cancer Patients and Survivors ACOGCOMMITTEEOPINION Number 747 (Replaces Committee Opinion Number 607, August 2014) Committee on Adolescent Health Care This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Adolescent Health Care in collaboration with committee members Erin A. Keyser, MD, and Sloane W. Berger-Chen, MD. Gynecologic Issues in Children and Adolescent Cancer Patients and Survivors (...) ABSTRACT:The diagnosisofcancer infemalesyoungerthan 20yearsisrare, withthe incidenceof17cases per 100,000 individuals per year in the United States. Although advancements in cancer therapy have dramatically improved childhood cancer survival, gynecologists should be aware of the increased risk of adverse reproductive healtheffectsfromeachtypeoftherapy.Canceranditstreatmentmayhaveimmediateordelayedadverseeffects on reproductive health. Gynecologists may be consulted for the following issues: pubertal

American College of Obstetricians and Gynecologists2018

177. Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children

Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2018

178. Use of plasma exchange in pediatric severe sepsis in children's hospitals

Use of plasma exchange in pediatric severe sepsis in children's hospitals PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2018

179. Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose (...) a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} Treating children and young people with a new diagnosis of type 1 diabetes with continuous subcutaneous insulin, compared with multiple daily injections, had no impact on HbA1c 12 months later. {{author}} {{($index , , , , , , , , , & . Joanne Blair 1, * , Andrew McKay 2 , Colin Ridyard 3 , Keith Thornborough 4

NIHR HTA programme2018

180. Staircase model to support children who have witnessed or been exposed to direct violence

Staircase model to support children who have witnessed or been exposed to direct violence Staircase model to support children who have witnessed or been exposed to direct violence We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Staircase model to support children who have witnessed or been exposed to direct violence Share: Reading time approx. 2 (...) minutes Introduction Children who have witnessed violence towards a parent may develop physical or psychological problems and have the same need for supporting interventions as children who have experienced direct violence. The Social care service centres in Sweden have the responsibility to administer interventions based on the needs of the individual child. The Staircase model is an individual counselling intervention that has been developed for children who have experienced violence within

Swedish Council on Technology Assessement2018