Latest & greatest articles for children

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This page lists the very latest high quality evidence on children and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for children

141. Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in Body Mass Index: A Randomized Clinical Trial.

Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in Body Mass Index: A Randomized Clinical Trial. Importance: Prevention of obesity during childhood is critical for children in underserved populations, for whom obesity prevalence and risk of chronic disease are highest. Objective: To test the effect of a multicomponent behavioral intervention on child body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) growth (...) trajectories over 36 months among preschool-age children at risk for obesity. Design, Setting, and Participants: A randomized clinical trial assigned 610 parent-child pairs from underserved communities in Nashville, Tennessee, to a 36-month intervention targeting health behaviors or a school-readiness control. Eligible children were between ages 3 and 5 years and at risk for obesity but not yet obese. Enrollment occurred from August 2012 to May 2014; 36-month follow-up occurred from October 2015 to June

JAMA2018

142. Safety and Side Effects of Rifampin versus Isoniazid in Children.

Safety and Side Effects of Rifampin versus Isoniazid in Children. BACKGROUND: The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life-threatening forms of tuberculosis disease. The current standard treatment - 9 months of isoniazid - has been associated with poor adherence and toxic effects, which have hampered the effectiveness of the drug. In adults, treatment with 4 months of rifampin has been shown to be safer (...) and to have higher completion rates than 9 months of isoniazid. METHODS: In this multicenter, open-label trial, we randomly assigned 844 children (<18 years of age) with latent M. tuberculosis infection to receive either 4 months of rifampin or 9 months of isoniazid. The primary outcome was adverse events of grade 1 to 5 that resulted in the permanent discontinuation of a trial drug. Secondary outcomes were treatment adherence, side-effect profile, and efficacy. Independent review panels whose members

NEJM2018

145. A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes

A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes 29873107 2018 06 19 1464-5491 2018 Jun 05 Diabetic medicine : a journal of the British Diabetic Association Diabet. Med. A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes. 10.1111/dme.13703 To compare systematically the impact of two novel insulin-dosing algorithms (the Pankowska Equation and the Food Insulin (...) Index) with carbohydrate counting on postprandial glucose excursions following a high fat and a high protein meal. A randomized, crossover trial at two Paediatric Diabetes centres was conducted. On each day, participants consumed a high protein or high fat meal with similar carbohydrate amounts. Insulin was delivered according to carbohydrate counting, the Pankowska Equation or the Food Insulin Index. Subjects fasted for 5 h following the test meal and physical activity was standardized

EvidenceUpdates2018

146. Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism

Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism 29864629 2018 07 31 1879-2472 168 2018 Aug Thrombosis research Thromb. Res. Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism. 1-4 S0049-3848(18)30367-0 10.1016/j.thromres.2018.05.026 The pulmonary embolism rule out criteria (PERC) reliably predicts a low probability of PE in adults. We examine (...) the diagnostic accuracy of the objective components of the PERC rule in children previously tested for PE. Children aged 5-17 who had a D-dimer or pulmonary vascular imaging ordered from 2004 to 2014 in a large multicenter hospital network were identified by query of administrative databases. Using explicit, predefined methods, trained abstracters selected charts of children clearly tested for PE, collected the 8 objective variables for PERC, and determined PE criterion standard status (image or autopsy

EvidenceUpdates2018

147. Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department

Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department 29986857 2018 07 17 1488-2329 190 27 2018 Jul 09 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department. E816-E822 10.1503/cmaj.170406 (...) There is uncertainty about which children with minor head injury need to undergo computed tomography (CT). We sought to prospectively validate the accuracy and potential for refinement of a previously derived decision rule, Canadian Assessment of Tomography for Childhood Head injury (CATCH), to guide CT use in children with minor head injury. This multicentre cohort study in 9 Canadian pediatric emergency departments prospectively enrolled children with blunt head trauma presenting with a Glasgow Coma Scale score

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

148. Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study

Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study 29998359 2018 07 12 1496-8975 2018 Jul 11 Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Optimal inspiratory pressure for face mask ventilation in paralyzed and unparalyzed children to prevent gastric insufflation: a prospective, randomized, non-blinded study. 10.1007/s12630-018-1183-2 Gastric (...) insufflation is common during face mask ventilation and results in unfavourable respiratory events in children. The purpose of this study was to evaluate the effect of a muscle relaxant on gastric insufflation and determine the optimal inspiratory pressure during face mask ventilation in children. Children aged one month to five years were randomly assigned to neuromuscular blocker (NM) or non-neuromuscular blocker (non-NM) groups. After administering intravenous anesthetics, face mask ventilation

EvidenceUpdates2018

150. Best Practices on Periodicity of Examination, Preventive Dental Services, Anticipatory Guidance/Counseling, and Oral Treatment for Infants, Children, and Adolescents

Best Practices on Periodicity of Examination, Preventive Dental Services, Anticipatory Guidance/Counseling, and Oral Treatment for Infants, Children, and Adolescents

American Academy of Pediatric Dentistry2018

152. Staircase model to support children who have witnessed or been exposed to direct violence

Staircase model to support children who have witnessed or been exposed to direct violence Staircase model to support children who have witnessed or been exposed to direct violence We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Staircase model to support children who have witnessed or been exposed to direct violence Share: Reading time approx. 2 (...) minutes Introduction Children who have witnessed violence towards a parent may develop physical or psychological problems and have the same need for supporting interventions as children who have experienced direct violence. The Social care service centres in Sweden have the responsibility to administer interventions based on the needs of the individual child. The Staircase model is an individual counselling intervention that has been developed for children who have experienced violence within

Swedish Council on Technology Assessement2018

153. Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children

Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2018

154. Use of plasma exchange in pediatric severe sepsis in children's hospitals

Use of plasma exchange in pediatric severe sepsis in children's hospitals PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2018

155. Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose (...) a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} Treating children and young people with a new diagnosis of type 1 diabetes with continuous subcutaneous insulin, compared with multiple daily injections, had no impact on HbA1c 12 months later. {{author}} {{($index , , , , , , , , , & . Joanne Blair 1, * , Andrew McKay 2 , Colin Ridyard 3 , Keith Thornborough 4

NIHR HTA programme2018

156. Children

Children Top results for children - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for children The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

Trip Latest and Greatest2018

157. Chronic Cough Related to Acute Viral Bronchiolitis in Children

Chronic Cough Related to Acute Viral Bronchiolitis in Children Chronic Cough Related to Acute Viral Bronchiolitis in Children CHEST Expert Panel Report Anne B. Chang, MBBS, PhD, MPH; John J. Oppenheimer, MD; Bruce K. Rubin, MD; Miles Weinberger, MD, FCCP; and Richard S. Irwin, MD, Master FCCP; on behalf of the CHEST Expert Cough Panel BACKGROUND: Acute bronchiolitis is common in young children, and some children develop chronic cough after their bronchiolitis. We thus undertook systematic (...) reviews based on key questions (KQs) using the PICO (Population, Intervention, Comparison, Outcome) format. The KQs were: Among children with chronic cough (> 4 weeks) after acute viral bron- chiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta 2 agonist, montelukast); and (3) Inhaled osmotic agents like hypertonic saline? METHODS: We used the CHEST expert cough

American College of Chest Physicians2018

158. Antibiotics for prolonged wet cough in children.

Antibiotics for prolonged wet cough in children. BACKGROUND: Cough is a frequent symptom presenting to doctors. The most common cause of childhood chronic (greater than fours weeks' duration) wet cough is protracted bacterial bronchitis (PBB) in some settings, although other more serious causes can also present this way. Timely and effective management of chronic wet or productive cough improves quality of life and clinical outcomes. Current international guidelines suggest a course (...) of antibiotics is the first treatment of choice in the absence of signs or symptoms specific to an alternative diagnosis. This review sought to clarify the current evidence to support this recommendation. OBJECTIVES: To determine the efficacy of antibiotics in treating children with prolonged wet cough (excluding children with bronchiectasis or other known underlying respiratory illness) and to assess risk of harm due to adverse events. SEARCH METHODS: We undertook an updated search (from 2008 onwards) using

Cochrane2018

159. Blowing up a balloon with the nose helps restore hearing in children with glue ear

Blowing up a balloon with the nose helps restore hearing in children with glue ear Signal - Blowing up a balloon with the nose helps restore hearing in children with glue ear Dissemination Centre Discover Portal NIHR DC Discover Blowing up a balloon with the nose helps restore hearing in children with glue ear Published on 7 September 2015 The use of a simple nasal balloon can help restore hearing in children aged 4 to 11 with glue ear. After 3 months, this non-surgical treatment restored (...) normal hearing to 49.6% of children with glue ear compared with 38.3% receiving usual care. Children inflate the balloon by blowing it up with their noses rather than their mouths. The activity which is done three times a day can be taught by nurses in a GP surgery. Few non-surgical treatments exist for children with glue ear. Some, such as antibiotics, are used despite evidence they don’t work. It is hoped using the nasal balloon may help reduce this unnecessary use of antibiotics and reduce

NIHR Dissemination Centre2018

160. Diagnostic tests for autism spectrum disorder (ASD) in preschool children.

Diagnostic tests for autism spectrum disorder (ASD) in preschool children. BACKGROUND: Autism spectrum disorder (ASD) is a behaviourally diagnosed condition. It is defined by impairments in social communication or the presence of restricted or repetitive behaviours, or both. Diagnosis is made according to existing classification systems. In recent years, especially following publication of the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5; APA 2013), children (...) are given the diagnosis of ASD, rather than subclassifications of the spectrum such as autistic disorder, Asperger syndrome, or pervasive developmental disorder - not otherwise specified. Tests to diagnose ASD have been developed using parent or carer interview, child observation, or a combination of both. OBJECTIVES: Primary objectives1. To identify which diagnostic tools, including updated versions, most accurately diagnose ASD in preschool children when compared with multi-disciplinary team clinical

Cochrane2018