Latest & greatest articles for children

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Top results for children

23. Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT

Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need (...) . >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} This trial found no evidence of clinical benefit of including emollient bath additives in the standard management of childhood eczema. {{author}} {{($index , , , , , , , , , , , , , , , & . Miriam Santer 1, * , Kate Rumsby 1 , Matthew J Ridd 2 , Nick A Francis 3 , Beth Stuart 1 , Maria Chorozoglou 4 , Amanda Roberts 5 , Lyn Liddiard 2 , Claire Nollett 6 , Julie Hooper 1 , Martina Prude 1 , Wendy Wood 7 , Emma

NIHR HTA programme2018

24. Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbance in children with neurodisabilities: a systematic review

Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbance in children with neurodisabilities: a systematic review Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbance in children with neurodisabilities: a systematic review Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page (...) , † , Adwoa Parker 2 , Arabella Scantlebury 2 , Gemma Spiers 3 , Caroline Fairhurst 2 , Catherine Hewitt 2 , Kath Wright 4 , Vicki Dawson 5 , Heather Elphick 6 , Megan Thomas 7 1 Social Policy Research Unit, University of York, York, UK 2 York Trials Unit, Department of Health Sciences, University of York, York, UK 3 Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK 4 Centre for Reviews and Dissemination, University of York, York, UK 5 The Children’s Sleep Charity, Doncaster

NIHR HTA programme2018

25. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT

Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find (...) the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Any benefit from a short course of steroids for hearing loss in 2- to 8-year-old children with otitis media with effusion is likely to be small and of questionable clinical significance. {{author}} {{($index , , , , , , , , , , , , & . Nick A Francis 1, * , Cherry-Ann Waldron 2 , Rebecca Cannings-John 2 , Emma Thomas-Jones 2 , Thomas Winfield 3 , Victoria Shepherd 2 , Debbie Harris

NIHR HTA programme2018

27. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children 30267029 2018 10 25 1572-0241 113 10 2018 Oct The American journal of gastroenterology Am. J. Gastroenterol. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. 1524-1529 10.1038/s41395-018-0239-9 Environmental factors play an important role in the pathogenesis of Crohn's Disease (CD). In particular (...) exposed to maternal smoke. On multivariable analysis, a history of breastfeeding was inversely associated with complicated (B2/B3 disease) 0.65, CI 95% 0.44-96; P = 0.03) in pediatric CD. Maternal smoking during pregnancy was associated with increased risk of hospitalization during the 3-year follow-up period (OR 1.75, CI 95% 1.05-2.89; P = 0.03). Early life environmental factors influence the eventual phenotypes and disease course in CD. Lindoso Livia L Division of Pediatric Gastroenterology, Emory

EvidenceUpdates2018

28. Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients

Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients 30216124 2018 11 14 1527-7755 2018 Sep 14 Journal of clinical oncology : official journal of the American Society of Clinical Oncology J. Clin. Oncol. Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients (...) . JCO1800407 10.1200/JCO.18.00407 Purpose The aim of this work was to develop a clinical practice guideline for the prevention and treatment of Clostridium difficile infection (CDI) in children and adolescents with cancer and pediatric hematopoietic stem-cell transplantation (HSCT) patients. Methods An international multidisciplinary panel of experts in pediatric oncology and infectious diseases with patient advocate representation was convened. We performed systematic reviews of randomized controlled

EvidenceUpdates2018

29. Ambu(R) Aura Gain versus Ambu(R) Aura Once in children: a randomized, crossover study assessing oropharyngeal leak pressure and fibreoptic position

Ambu(R) Aura Gain versus Ambu(R) Aura Once in children: a randomized, crossover study assessing oropharyngeal leak pressure and fibreoptic position 30315506 2018 10 13 1496-8975 2018 Oct 12 Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Ambu® Aura Gain™ versus Ambu® Aura Once™ in children: a randomized, crossover study assessing oropharyngeal leak pressure and fibreoptic position. 10.1007/s12630-018-1235-7 The Ambu® Aura Gain™ is a new second-generation (...) ) vs 19 (6) cmH 2 O, respectively; mean difference [MD] - 2 cmH 2 O; 95% confidence interval [CI], - 3.8 to - 1.0; P = 0.001]. Mean (SD) insertion time was faster for Ambu® Aura Once™ than for Ambu® Aura Gain™ [8 (3) vs 10 (4) seconds, respectively; MD, - 2 sec; 95% CI, - 2.9 to - 1.2; P < 0.001]. There were no differences in ventilation quality, fibreoptic view, or blood staining. We conclude that Ambu® Aura Gain™ is a good alternative to the Ambu® Aura Once™ and an efficient device for children

EvidenceUpdates2018

30. Effect of Foster Care Intervention on Trajectories of General and Specific Psychopathology Among Children With Histories of Institutional Rearing: A Randomized Clinical Trial

Effect of Foster Care Intervention on Trajectories of General and Specific Psychopathology Among Children With Histories of Institutional Rearing: A Randomized Clinical Trial 30267045 2018 11 07 2168-6238 75 11 2018 Nov 01 JAMA psychiatry JAMA Psychiatry Effect of Foster Care Intervention on Trajectories of General and Specific Psychopathology Among Children With Histories of Institutional Rearing: A Randomized Clinical Trial. 1137-1145 10.1001/jamapsychiatry.2018.2556 It is unclear whether (...) early institutional rearing is associated with more problematic trajectories of psychopathology from childhood to adolescence and whether assignment to foster care mitigates this risk. To examine trajectories of latent psychopathology factors-general (P), internalizing (INT), and externalizing (EXT)-among children reared in institutions and to evaluate whether randomization to foster care is associated with reductions in psychopathology from middle childhood through adolescence. This longitudinal

EvidenceUpdates2018

31. Efficacy of preemptive analgesia on acute postoperative pain in children undergoing major orthopedic surgery of the lower extremities

Efficacy of preemptive analgesia on acute postoperative pain in children undergoing major orthopedic surgery of the lower extremities 30288096 2018 11 14 1178-7090 11 2018 Journal of pain research J Pain Res Efficacy of preemptive analgesia on acute postoperative pain in children undergoing major orthopedic surgery of the lower extremities. 2061-2070 10.2147/JPR.S175169 Children undergoing major orthopedic surgery of the lower extremities can experience severe postoperative pain; yet, the ideal (...) not demonstrate preemptive analgesic efficacy within 48 hours postoperatively in children undergoing extensive lower limb orthopedic surgery. Kim Do-Hyeong DH Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea, yschoi@yuhs.ac. Kim Namo N Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea, yschoi@yuhs.ac. Lee

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

32. Early Mobilization in Critically Ill Children: A Systematic Review

Early Mobilization in Critically Ill Children: A Systematic Review 30172429 2018 09 02 1097-6833 2018 Aug 29 The Journal of pediatrics J. Pediatr. Early Mobilization in Critically Ill Children: A Systematic Review. S0022-3476(18)30942-9 10.1016/j.jpeds.2018.07.037 To characterize how early mobilization is defined in the published literature and describe the evidence on safety and efficacy on early mobilization in critically ill children. Systematic search of randomized and nonrandomized studies (...) assessing early mobilization-based physical therapy in critically ill children under 18 years of age in MEDLINE, Embase, CINAHL, CENTRAL, the National Institutes of Health, Evidence in Pediatric Intensive Care Collaborative, Physiotherapy Evidence Database, and the Mobilization-Network. We extracted data to identify the types of mobility-based interventions and definitions for early, as well as barriers, feasibility, adverse events, and efficacy outcomes (mortality, morbidities, and length of stay

EvidenceUpdates2018

33. Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression

Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression 30287331 2018 11 16 1096-0260 118 2018 Oct 02 Preventive medicine Prev Med Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression. 7-15 S0091-7435(18)30299-8 10.1016/j.ypmed.2018.09.021 Depression contributes about 2% to the global burden of disease. A first onset of depressive disorder or subsyndromal depressive symptoms (...) is common in adolescence, indicating that early prevention is a priority. However, trials of preventive interventions for depression in youths show conflicting results. This systematic review and meta-analysis investigated the effectiveness of group-based cognitive behavioral therapy (GB-CBT) as a preventive intervention targeting subsyndromal depression in children and adolescents. In addition, the impact of different covariates (type of comparator and use of booster sessions) was assessed. Relevant

EvidenceUpdates2018

34. Transversus Abdominal Plane Block in Children: Efficacy and Safety: A Randomized Clinical Study and Pharmacokinetic Profile

Transversus Abdominal Plane Block in Children: Efficacy and Safety: A Randomized Clinical Study and Pharmacokinetic Profile 30198931 2018 09 10 1526-7598 2018 Sep 05 Anesthesia and analgesia Anesth. Analg. Transversus Abdominal Plane Block in Children: Efficacy and Safety: A Randomized Clinical Study and Pharmacokinetic Profile. 10.1213/ANE.0000000000003736 The transversus abdominis plane (TAP) block has become a common regional anesthesia technique for pain management in a wide variety (...) of abdominal procedures. Evidence to support any particular local anesthetic regimen as well as pharmacokinetic and systemic toxicity risks of TAP block remain insufficiently studied in children. The aim of this study was to compare the analgesic effects and investigate pharmacokinetic profile of levobupivacaine after ultrasound-guided TAP block using a low volume/high concentration (LVHC) or a high volume/low concentration (HVLC) solution in children. This prospective randomized study included children

EvidenceUpdates2018

35. Diagnosis, Evaluation, and Management of High Blood Pressure in Children and Adolescents

Diagnosis, Evaluation, and Management of High Blood Pressure in Children and Adolescents 30126937 2018 09 04 1098-4275 142 3 2018 Sep Pediatrics Pediatrics Diagnosis, Evaluation, and Management of High Blood Pressure in Children and Adolescents. e20182096 10.1542/peds.2018-2096 Systemic hypertension is a major cause of morbidity and mortality in adulthood. High blood pressure (HBP) and repeated measures of HBP, hypertension (HTN), begin in youth. Knowledge of how best to diagnose, manage (...) , and treat systemic HTN in children and adolescents is important for primary and subspecialty care providers. To provide a technical summary of the methodology used to generate the 2017 "Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents," an update to the 2004 "Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents." Medline, Cochrane Central Register of Controlled Trials, and Excerpta Medica

EvidenceUpdates2018

36. Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis

Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis 30383099 2018 11 01 2168-6238 2018 Oct 31 JAMA psychiatry JAMA Psychiatry Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis. 10.1001/jamapsychiatry.2018.3070 Anxiety disorders are common in children and adolescents, and uncertainty remains regarding the optimal strategy (...) of psychotherapies in this population. To compare and rank the different types of psychotherapies and the different ways of delivering psychological treatments for anxiety disorders in children and adolescents. PubMed, Cochrane Central Register of Controlled Trials, EMBASE, PsycINFO, Web of Science, CINAHL (Cumulative Index to Nursing and Allied Health Literature), ProQuest Dissertations, LILACS (Literatura Latino Americana em Ciências da Saúde), international trial registers, and US Food and Drug Administration

EvidenceUpdates2018

37. Treatment of Varicocele in Children and Adolescents: A Systematic Review and Meta-analysis from the European Association of Urology/European Society for Paediatric Urology Guidelines Panel

Treatment of Varicocele in Children and Adolescents: A Systematic Review and Meta-analysis from the European Association of Urology/European Society for Paediatric Urology Guidelines Panel 30316583 2018 10 14 1873-7560 2018 Oct 10 European urology Eur. Urol. Treatment of Varicocele in Children and Adolescents: A Systematic Review and Meta-analysis from the European Association of Urology/European Society for Paediatric Urology Guidelines Panel. S0302-2838(18)30731-0 10.1016/j.eururo.2018.09.042 (...) The benefits and harms of intervention (surgical or radiological) versus observation in children and adolescents with varicocele are controversial. To systematically evaluate the evidence regarding the short- and long-term outcomes of varicocele treatment in children and adolescents. A systematic review and meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement. A priori protocol was registered to PROSPERO (CRD42018084871

EvidenceUpdates2018

38. Hospitalization for Respiratory Syncytial Virus in Children with Down Syndrome Less than 2 Years of Age: A Systematic Review and Meta-Analysis

Hospitalization for Respiratory Syncytial Virus in Children with Down Syndrome Less than 2 Years of Age: A Systematic Review and Meta-Analysis 30266507 2018 09 29 1097-6833 2018 Sep 25 The Journal of pediatrics J. Pediatr. Hospitalization for Respiratory Syncytial Virus in Children with Down Syndrome Less than 2 Years of Age: A Systematic Review and Meta-Analysis. S0022-3476(18)31116-8 10.1016/j.jpeds.2018.08.006 To compare the respiratory syncytial virus (RSV)-related hospitalization rate (...) , hospital length of stay (LOS), and need for assisted ventilation in children aged <2 years with Down syndrome and those without Down syndrome. MEDLINE, Embase, and CINAHL databases were searched from inception up to December 2017. Studies that provided data on RSV-related hospitalization in children aged <2 years with Down syndrome and those without Down syndrome were included. Data were independently extracted in pairs by 2 reviewers and synthesized with random-effects meta-analysis. In 10 studies

EvidenceUpdates2018