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Latest & greatest articles for children
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on children or other clinical topics then use Trip today.
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Dance Intervention for Mexican Family Caregivers of Children With Developmental Disability: A Pilot Study. Introduction: There are 7.1 million people living with a disability in Mexico. Of these individuals, 7% are children and adolescents with developmental disabilities. Mexican women caring for children with a developmental disability are at risk of psychological stress, which may be prevented with physical activity such as dance. Therefore, the purpose of this pilot study was to examine (...) (a) the feasibility of implementing the dance intervention, (b) the mothers' satisfaction with the intervention, and (c) the changes in stress level experienced by the mothers on completion of the intervention. Method: A one-group pretest-posttest design was used. The Salsa dance intervention was given in nine 60-minute sessions, twice a week in Veracruz, Mexico. The sample included 14 mothers of children with disabilities. The outcome, stress level, was measured with the validated Questionnaire of Perceived
[Effect of an intervention based on child-care centers to reduce risk behaviors for obesity in preschool children]. Preschool age is a critical stage for health promotion and prevention of obesity, which is an emerging public health problem in children. The aim of this study was to design and evaluate the effect of a multifaceted intervention based on child-care centers to reduce risk behaviors for obesity among preschool children.A 12-month cluster-randomized community trial was conducted (...) in 16 Mexican Institute of Social Security child-care centers in Mexico City. Children between 2 and 4 years of age enrolled in the selected child-care centers participated in the study. Intervention comprised 12 weekly curriculum sessions for the children, and six family workshops. Changes in children's dietary and physical activity, food availability at home, and maternal feeding styles were determined after 6 and 12 months. Changes within groups among stages, and between groups by stage were
[Comparative study of the conventional scheme and prolonged treatment with steroids on primary steroid-sensitive nephrotic syndrome in children]. In the steroid-sensitive nephrotic syndrome (SSNS) the prolonged treatment with steroids could decrease the frequency of relapses. We conducted a comparative study of prolonged steroid scheme and the usual treatment of primary SSNS to assess: the number of patients with relapses, mean time to treatment initiation, to remission and to first relapse
Evaluation of Long-term Risk of Epilepsy, Psychiatric Disorders, and Mortality Among Children With Recurrent Febrile Seizures: A National Cohort Study in Denmark Febrile seizures occur in 2% to 5% of children between the ages of 3 months and 5 years. Many affected children experience recurrent febrile seizures. However, little is known about the association between recurrent febrile seizures and subsequent prognosis.To estimate the risk of recurrent febrile seizures and whether (...) there is an association over long-term follow-up between recurrent febrile seizures and epilepsy, psychiatric disorders, and death in a large, nationwide, population-based cohort in Denmark.This population-based cohort study evaluated data from all singleton children born in Denmark between January 1, 1977, and December 31, 2011, who were identified through the Danish Civil Registration System. Children born in Denmark who were alive and residing in Denmark at age 3 months were included (N = 2 103 232). The study
Efficacy of High-Flow Nasal Cannula vs Standard Oxygen Therapy or Nasal Continuous Positive Airway Pressure in Children with Respiratory Distress: A Meta-Analysis To evaluate the efficacy of high-flow nasal cannula (HFNC) oxygen therapy in providing respiratory support of children with acute lower respiratory infection (ALRI), hypoxemia, and respiratory distress.We performed a meta-analysis of randomized controlled trials that compared HFNC and standard flow oxygen therapy or nasal continuous (...) positive airway pressure (nCPAP) and reported treatment failure as an outcome. Data were synthesized using Mann-Whitney U test.Compared with standard oxygen therapy, HFNC significantly reduced treatment failure (risk ratio [RR] 0.49, 95% CI 0.40-0.60, P < .001) in children with mild hypoxemia (arterial pulse oximetry [SpO2] >90% on room air). HFNC had an increased risk of treatment failure compared with nCPAP in infants age 1-6 months with severe hypoxemia (SpO2 <90% on room air or SpO2 >90
Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents Attention-deficit/hyperactivity disorder (ADHD) is 1 of the most common neurobehavioral disorders of childhood and can profoundly affect children's academic achievement, well-being, and social interactions. The American Academy of Pediatrics first published clinical recommendations for evaluation and diagnosis of pediatric ADHD in 2000; recommendations (...) recommendations. Therefore, only incremental updates have been made in this guideline revision, including the addition of a key action statement related to diagnosis and treatment of comorbid conditions in children and adolescents with ADHD. The accompanying process of care algorithm has also been updated to assist in implementing the guideline recommendations. Throughout the process of revising the guideline and algorithm, numerous systemic barriers were identified that restrict and/or hamper pediatric
Effectiveness and Safety of Primary Thromboprophylaxis in Children with Cancer: A Systematic Review of the Literature and Network Meta-Analysis Thromboembolism (TE) is a well-recognized complication of pediatric cancer and can lead to mortality and excess morbidity. There is conflicting evidence about the effectiveness and safety of thromboprophylaxis in children. We conducted a systematic literature review and network meta-analysis of primary pharmacological thromboprophylaxis in children (...) AT replacement, LMWH, VKA, and SOC. Current evidence suggests that low-dose LMWH is effective and safe to prevent TE in children with cancer but is insufficient to conclude if AT replacement or VKA are effective thromboprophylaxis options. Further research, notably randomized controlled trials enrolling children with diverse types of cancer, is crucially needed.Georg Thieme Verlag KG Stuttgart · New York.
Mass deworming for improving health and cognition of children in endemic helminth areas: A systematic review and individual participant data network meta-analysis Mass deworming programs have little effect on nutritional status and cognitive development on a population level What is the aim of this review? This Campbell systematic review evaluates what factors modify the effects of mass deworming for soil-transmitted helminths on nutritional status and cognition in children in endemic helminth (...) areas using individual participant data. The effectiveness and cost-effectiveness of mass deworming of children to improve child health and other outcomes is debated. This independent analysis reinforces the case against mass deworming at a population- level, finding little effect on nutritional status or cognition. However, children with heavier intensity infections may benefit more. What is this review about? Soil-transmitted helminthiasis (STH) and schistosomiasis affects over 800 million people
Effectiveness of continuing professional development training of welfare professionals on outcomes for children and young people Little evidence of the effectiveness of continuing professional development (CPD) What is the aim of this review? This Campbell systematic review examines the effects of continuing professional development (CPD) approaches for education and welfare practitioners on: educational and social outcomes for children and young people; and outcomes for practitioners (...) . The review summarizes evidence from 51 moderate- quality studies, including 48 randomized controlled trials and three quasi-experiments. Continuing professional development (CPD) aims to improve outcomes for the children and young people with whom educational and welfare professionals work. There is no clear evidence that CPD in education improves student academic outcomes. What is this review about? CPD is delivered in a variety of settings by different kinds of ‘trainers’ or educators for differing
Diamorphine hydrochloride (Ayendi) - acute severe nociceptive pain in children and adolescents Final Appraisal Recommendation Advice No: 1719 – November 2019 Diamorphine hydrochloride (Ayendi ® ) 720 microgram/actuation and 1600 microgram/actuation Nasal Spray Limited submission by Wockhardt UK Ltd In reaching the above recommendation AWMSG has taken account of the appraisal documentation prepared by the AWMSG Secretariat (reference number 2406), which includes the AWMSG Secretariat Assessment (...) nociceptive pain in children and adolescents 2 to 15 years of age in a hospital setting. Ayendi ® nasal spray should be administered in the emergency setting by practitioners experienced in the administration of opioids in children and with the appropriate monitoring. Statement of use: No part of this recommendation may be reproduced without the whole recommendation being quoted in full and cited as: All Wales Medicines Strategy Group Final Appraisal Recommendation – 1719: Diamorphine hydrochloride
Dental Lasers for Caries Removal in Children Is a Good Alternative to Conventional Mechanical Methods UTCAT3398, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Dental Lasers for Caries Removal in Children Is a Good Alternative to Conventional Mechanical Methods Clinical Question For children with caries, is Er:YAG laser application an effective treatment for caries removal and cavity preparation compared (...) lasers for caries removal when comparing restoration retention, marginal discoloration and marginal adaptation. #2) Montedori/2016 662 participants in 9 trials (age range 3.5 to 84 years old) Systematic review of randomized trials Key results Four trials included children/adolescents; four trials included adults only; and one trial included children/adolescents and adults. Due to the available studies having small sample sizes and high risk of bias, “evidence was insufficient to support the use
Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and meta-analysis Nutritional supplements may improve development of infants born small (preterm or small for gestational age [SGA]) but may increase the risk of later metabolic disease. We conducted a systematic review and meta-analysis to assess the effects of macronutrient supplements for infants born small on later development (...) no differences in cognitive scores (mean difference [MD] 0.57; 95% CI -0.71 to 1.84; P = 0.38) or motor scores (MD 1.16; 95% CI -0.32 to 2.65; P = 0.12) between supplemented and unsupplemented groups. However, fewer supplemented children had motor impairment (RR 0.76; 95% CI 0.62 to 0.94; P = 0.01). In subgroup analyses, supplementation improved cognitive scores in boys (MD 5.60; 95% CI 1.07 to 10.14; P = 0.02), but not girls born small (MD -2.04; 95% CI -7.04 to 2.95; P = 0.42), and did not alter cognitive
Allogenic Mesenchymal Stromal Cell Infusion Therapy for Children with Severe Generalised Recessive Dystrophic Epidermolysis Bullosa NHS England » Allogenic Mesenchymal Stromal Cell Infusion Therapy for Children with Severe Generalised Recessive Dystrophic Epidermolysis Bullosa Search Search Menu Allogenic Mesenchymal Stromal Cell Infusion Therapy for Children with Severe Generalised Recessive Dystrophic Epidermolysis Bullosa Document first published: 24 July 2019 Page updated: 24 July 2019 (...) Topic: Publication type: , This clinical commissioning policy statement relates to the commissioning arrangements for allogenic mesenchymal stromal cell infusion therapy for children with severe generalised recessive dystrophic epidermolysis bullosa. Document PDF 32 KB 3 pages Document PDF 28 KB 2 pages Document PDF 82 KB 5 pages Document PDF 121 KB 2 pages