Latest & greatest articles for cardiovascular disease

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Top results for cardiovascular disease

641. Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men

Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men 18469240 2008 05 12 2008 06 11 2015 11 19 1938-3207 87 5 2008 May The American journal of clinical nutrition Am. J. Clin. Nutr. Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men. 1204-11 Betel nut chewing is related to several kinds of cancer, metabolic syndrome, and type 2 diabetes. Whether it is associated (...) with a greater risk of cardiovascular disease (CVD) and all-cause mortality, however, remains unclear. We aimed to investigate the association between betel nut chewing and CVD and all-cause mortality. A baseline cohort of 56,116 male participants > or = 20 y old were recruited from 4 nationwide health screening centers in Taiwan in 1998 and 1999. Cox proportional hazards regression analyses were used to estimate the relative risks (RRs) of CVD and all-cause mortality for betel nut chewers during an 8-y

EvidenceUpdates2008

642. Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies.

Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies. Individuals with type 2 diabetes mellitus have increased cardiovascular disease risk compared with those without diabetes. Treatment of the residual risk, other than blood pressure and LDL-cholesterol control, remains important as the rate of diabetes increases worldwide. The accelerated atherosclerosis and cardiovascular disease in diabetes is likely to be multifactorial and therefore several

Lancet2008 Full Text: Link to full Text with Trip Pro

643. Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies.

Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. BACKGROUND: Clinical use of criteria for metabolic syndrome to simultaneously predict risk of cardiovascular disease and diabetes remains uncertain. We investigated to what extent metabolic syndrome and its individual components were related to risk for these two diseases in elderly populations. METHODS: We related metabolic syndrome (defined on the basis of criteria from (...) the Third Report of the National Cholesterol Education Program) and its five individual components to the risk of events of incident cardiovascular disease and type 2 diabetes in 4812 non-diabetic individuals aged 70-82 years from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). We corroborated these data in a second prospective study (the British Regional Heart Study [BRHS]) of 2737 non-diabetic men aged 60-79 years. FINDINGS: In PROSPER, 772 cases of incident cardiovascular

Lancet2008

644. Coarse particulate matter air pollution and hospital admissions for cardiovascular and respiratory diseases among Medicare patients.

Coarse particulate matter air pollution and hospital admissions for cardiovascular and respiratory diseases among Medicare patients. CONTEXT: Health risks of fine particulate matter of 2.5 microm or less in aerodynamic diameter (PM2.5) have been studied extensively over the last decade. Evidence concerning the health risks of the coarse fraction of greater than 2.5 microm and 10 microm or less in aerodynamic diameter (PM10-2.5) is limited. OBJECTIVE: To estimate risk of hospital admissions (...) for cardiovascular and respiratory diseases associated with PM10-2.5 exposure, controlling for PM2.5. DESIGN, SETTING, AND PARTICIPANTS: Using a database assembled for 108 US counties with daily cardiovascular and respiratory disease admission rates, temperature and dew-point temperature, and PM10-2.5 and PM2.5 concentrations were calculated with monitoring data as an exposure surrogate from January 1, 1999, through December 31, 2005. Admission rates were constructed from the Medicare National Claims History

JAMA2008 Full Text: Link to full Text with Trip Pro

645. Egg consumption in relation to cardiovascular disease and mortality: the Physicians` Health Study

Egg consumption in relation to cardiovascular disease and mortality: the Physicians` Health Study 18400720 2008 04 10 2008 04 28 2016 12 03 1938-3207 87 4 2008 Apr The American journal of clinical nutrition Am. J. Clin. Nutr. Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study. 964-9 A reduction in dietary cholesterol is recommended to prevent cardiovascular disease (CVD). Although eggs are important sources of cholesterol and other nutrients (...) 17092383 Med Sci Monit. 2007 Jan;13(1):CR1-8 17179903 Prev Med. 2007 Feb;44(2):135-42 17069878 BMJ. 1990 Mar 24;300(6727):771-3 2322737 Am J Clin Nutr. 1992 Jun;55(6):1060-70 1534437 Circulation. 1996 Oct 1;94(7):1795-800 8840887 BMJ. 1997 Jan 11;314(7074):112-7 9006469 Am J Clin Nutr. 2008 Nov;88(5):1448-9; author reply 1449-50 18996883 Am J Clin Nutr. 2008 Apr;87(4):799-800 18400699 Adult Aged Aged, 80 and over Cardiovascular Diseases epidemiology mortality Cholesterol, Dietary administration

EvidenceUpdates2008 Full Text: Link to full Text with Trip Pro

646. All-cause and Cardiovascular Disease Mortality Increased With Metabolic Syndrome in Taiwanese

All-cause and Cardiovascular Disease Mortality Increased With Metabolic Syndrome in Taiwanese 18239592 2008 03 03 2008 05 22 2008 03 03 1930-7381 16 3 2008 Mar Obesity (Silver Spring, Md.) Obesity (Silver Spring) All-cause and cardiovascular disease mortality increased with metabolic syndrome in Taiwanese. 684-9 10.1038/oby.2007.112 This study aimed to investigate the relationship between mortality and metabolic syndrome using the America Heart Association/National Heart Lung Blood Institute (...) (AHA/NHLBI) and International Diabetes Federation (IDF) definitions in a Taiwanese cohort. A total of 124,513 participants, aged 20-94 years, from four nationwide health centers in Taiwan were recruited from 1998 to 1999. Cox proportional hazard regression analyses were used to estimate the relative risks (RRs) for all-cause and cardiovascular disease (CVD) mortality for those with metabolic syndrome compared to those without metabolic syndrome over 8 years of follow-up. The baseline prevalence

EvidenceUpdates2008

647. The association of smoking and cardiovascular disease in a population with low cholesterol levels: a study of 648,346 men from the Korean national health system prospective cohort study

The association of smoking and cardiovascular disease in a population with low cholesterol levels: a study of 648,346 men from the Korean national health system prospective cohort study 18239177 2008 02 26 2008 03 31 2016 11 22 1524-4628 39 3 2008 Mar Stroke Stroke The association of smoking and cardiovascular disease in a population with low cholesterol levels: a study of 648,346 men from the Korean national health system prospective cohort study. 760-7 10.1161/STROKEAHA.107.494823 (...) The association of smoking with cardiovascular diseases in populations with low cholesterol levels is unclear and this lack of clarity may have contributed to the very high prevalence of smoking in East Asian men. The effect of smoking on stroke subtypes is particularly unclear. We used data from a prospective cohort study of 648,346 Korean men aged 30 to 64 years at their baseline assessment in 1992. Mean (SD) total cholesterol at baseline was 4.9 (1.0) mmol/L and 59% of the men were current smokers. Over

EvidenceUpdates2008

648. Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease

Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease 18359320 2008 03 24 2008 05 15 2008 03 24 0002-9149 101 7 2008 Apr 01 The American journal of cardiology Am. J. Cardiol. Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease. 992-8 10.1016/j.amjcard.2007.11.045 An attenuated heart rate (HR (...) ) response to exercise, or chronotropic incompetence, has been shown to predict adverse cardiac events in subjects without known cardiovascular disease (CVD). The aim of the present study was to investigate whether chronotropic incompetence independently predicts acute myocardial infarction (AMI) in middle-aged men. In addition to previously established chronotropic incompetence variables, we focused on a new chronotropic incompetence variable, the HR increase from 40% to 100% of maximal work capacity

EvidenceUpdates2008

649. Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort.

Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort. BACKGROUND: Around 80% of all cardiovascular deaths occur in developing countries. Assessment of those patients at high risk is an important strategy for prevention. Since developing countries have limited resources for prevention strategies that require laboratory testing, we assessed if a risk prediction method that did not require any laboratory tests could (...) be as accurate as one requiring laboratory information. METHODS: The National Health and Nutrition Examination Survey (NHANES) was a prospective cohort study of 14 407 US participants aged between 25-74 years at the time they were first examined (between 1971 and 1975). Our follow-up study population included participants with complete information on these surveys who did not report a history of cardiovascular disease (myocardial infarction, heart failure, stroke, angina) or cancer, yielding an analysis

Lancet2008 Full Text: Link to full Text with Trip Pro

650. Lipoprotein(a) and Cardiovascular Disease in Ethnic Chinese: The Chin-Shan Community Cardiovascular Cohort Study

Lipoprotein(a) and Cardiovascular Disease in Ethnic Chinese: The Chin-Shan Community Cardiovascular Cohort Study 18089660 2008 01 28 2008 04 03 2008 01 28 0009-9147 54 2 2008 Feb Clinical chemistry Clin. Chem. Lipoprotein(a) and cardiovascular disease in ethnic Chinese: the Chin-Shan Community Cardiovascular Cohort Study. 285-91 Little is known about lipoprotein(a) [Lp(a)] as a predictor of vascular events among ethnic Chinese. We prospectively investigated the association of Lp (...) (a) with cardiovascular disease and all-cause death in a community-based cohort. We conducted a community-based prospective cohort study of 3484 participants (53% women; age range, 35-97 years) who had complete lipid measurements and were free of a cardiovascular disease history at the time of recruitment. Over a median follow-up of 13.8-years, we documented 210 cases of stroke, 122 cases of coronary heart disease (CHD), and 781 deaths. The incidences for each event increased appreciably with Lp(a) quartile

EvidenceUpdates2008

651. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: A preventive cardiology information system (PreCIS) database cohort study

Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: A preventive cardiology information system (PreCIS) database cohort study 18240236 2008 02 25 2008 04 07 2015 11 19 0004-3591 58 2 2008 Feb Arthritis and rheumatism Arthritis Rheum. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study. 623 (...) -30 10.1002/art.23121 Uric acid is a product of the activity of xanthine oxidase, an enzyme linked to oxidative stress, endothelial dysfunction, and heart failure. It is unclear whether adding uric acid levels to the assessment of cardiovascular risk might contribute to the improved ability to stratify cardiovascular risk. The purpose of this study was to evaluate the prognostic value of serum uric acid levels in a large cohort of men and women at high risk of cardiovascular disease. Serum uric

EvidenceUpdates2008

652. Tissue angiotensin-converting enzyme inhibitors for the prevention of cardiovascular disease in patients with diabetes mellitus without left ventricular systolic dysfunction or clinical evidence of heart failure

Tissue angiotensin-converting enzyme inhibitors for the prevention of cardiovascular disease in patients with diabetes mellitus without left ventricular systolic dysfunction or clinical evidence of heart failure 18095949 2007 12 21 2008 04 11 2009 11 03 1463-1326 10 1 2008 Jan Diabetes, obesity & metabolism Diabetes Obes Metab Tissue angiotensin-converting enzyme inhibitors for the prevention of cardiovascular disease in patients with diabetes mellitus without left ventricular systolic (...) dysfunction or clinical evidence of heart failure: a pooled meta-analysis of randomized placebo-controlled clinical trials. 41-52 The aim of this study was to determine the role of tissue angiotensin-converting enzyme (ACE) inhibitors in the prevention of cardiovascular disease in patients with diabetes mellitus without left ventricular systolic dysfunction or clinical evidence of heart failure in randomized placebo-controlled clinical trials using pooled meta-analysis techniques. Randomized placebo

EvidenceUpdates2008

653. Relation Between Red Blood Cell Distribution Width and Cardiovascular Event Rate in People With Coronary Disease

Relation Between Red Blood Cell Distribution Width and Cardiovascular Event Rate in People With Coronary Disease 18172029 2008 01 16 2008 01 16 1524-4539 117 2 2008 Jan 15 Circulation Circulation Relation Between Red Blood Cell Distribution Width and Cardiovascular Event Rate in People With Coronary Disease. 163-168 BACKGROUND: Higher levels of red blood cell distribution width (RDW) may be associated with adverse outcomes in patients with heart failure. We examined the association between RDW (...) and the risk of all-cause mortality and adverse cardiovascular outcomes in a population of people with coronary disease who were free of heart failure at baseline. METHODS AND RESULTS: We performed a post hoc analysis of data from the Cholesterol and Recurrent Events study. Baseline RDW was measured in 4111 participants who were randomized to receive pravastatin 40 mg daily or placebo and followed for a median of 59.7 months. We used Cox proportional hazards models to examine the association between RDW

EvidenceUpdates2008

654. A prospective community-population-registry based cohort study of the association between betel-quid chewing and cardiovascular disease in men in Taiwan (KCIS no. 19)

A prospective community-population-registry based cohort study of the association between betel-quid chewing and cardiovascular disease in men in Taiwan (KCIS no. 19) 18175739 2008 01 07 2008 02 28 2015 11 19 0002-9165 87 1 2008 Jan The American journal of clinical nutrition Am. J. Clin. Nutr. A prospective community-population-registry based cohort study of the association between betel-quid chewing and cardiovascular disease in men in Taiwan (KCIS no. 19). 70-8 Betel-quid chewing (...) , a recognized risk factor for oral cancer, was shown to be a contributory cause of metabolic syndrome in humans, which implies a greater likelihood of developing cardiovascular disease (CVD) among those with the betel habit. This study investigated the effect of betel chewing on the risk of developing overt CVD. We used the prospective cohort data derived from a community-population-registry-based integrated screening program to quantify the effect of betel-quid chewing on the incidence of newly diagnosed

EvidenceUpdates2008

655. Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.

Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension. CONTEXT: The NPPA gene codes for the precursor of atrial natriuretic polypeptide, suggesting that NPPA may modulate the efficacy of some antihypertensive drugs. OBJECTIVE: To test whether participants with minor NPPA alleles in the T2238C or G664A variants had different rates of cardiovascular disease or blood pressure (BP) changes than common allele homozygotes (...) -converting enzyme inhibitor (lisinopril; n = 8233), or an alpha-blocker (doxazosin; n = 8195). MAIN OUTCOME MEASURE: The primary outcome measure was coronary heart disease (CHD), defined as fatal CHD or nonfatal myocardial infarction (mean follow-up, 4.9 years). Secondary outcomes were stroke, all-cause mortality, combined cardiovascular disease outcomes, and 6-month systolic and diastolic BP changes. Genotype x treatment interactions were tested where genotypes were modeled additively and dominantly. RESULTS: Depending on genotype

JAMA2008

656. Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis

Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis Berger JS, Brown DL, Becker RC CRD summary The authors concluded that low-dose aspirin therapy reduced the incidence of adverse cardiovascular events and all-cause mortality in patients with stable cardiovascular disease, but increased the risk of severe (...) bleeding. The authors' conclusion reflected the evidence presented, but poor reporting of the review methods and potential for language bias made the reliability of the authors' conclusion unclear. Authors' objectives To evaluate the benefit and risk of low-dose aspirin in patients with stable cardiovascular disease. Searching MEDLINE was searched from 1966 to March 2006. Search terms were reported. Reference lists of review articles were searched and major scientific meetings were monitored

DARE.2008

657. Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data regis

Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data regis Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs (...) using data registries Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data registries Ara R, Pandor A, Tumur I, Paisley S, Duenas A, Williams R, Wilkinson A, Durrington P, Chilcott J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each

NHS Economic Evaluation Database.2008

658. Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model

Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model Ara R, Pandor A, Tumur I, Paisley S, Duenas A, Williams R, Rees A, Wilkinson A, Durrington P, Chilcott (...) J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to examine the cost-effectiveness of long-term ezetimibe (EZE) monotherapy in comparison with no treatment in patients with established cardiovascular disease

NHS Economic Evaluation Database.2008

659. Combination polypharmacy for cardiovascular disease prevention in men: a decision analysis and cost-effectiveness model

Combination polypharmacy for cardiovascular disease prevention in men: a decision analysis and cost-effectiveness model Combination polypharmacy for cardiovascular disease prevention in men: a decision analysis and cost-effectiveness model Combination polypharmacy for cardiovascular disease prevention in men: a decision analysis and cost-effectiveness model Newman J, Grobman W A, Greenland P Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of a combination of four fixed-dose medications (simvastatin, captopril, hydrochlorothiazide, and atenolol) for the prevention of primary cardiovascular disease (CVD) in men aged over 55 years without CVD, hypertension, or dyslipidaemia

NHS Economic Evaluation Database.2008

660. The impact of prevention on reducing the burden of cardiovascular disease

The impact of prevention on reducing the burden of cardiovascular disease The impact of prevention on reducing the burden of cardiovascular disease The impact of prevention on reducing the burden of cardiovascular disease Kahn R, Robertson R M, Smith R, Eddy D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical (...) assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the potential cost-effectiveness of 11 interventions recommended to prevent cardiovascular disease (CVD) in the US population of eligible individuals aged 20 to 80 years. The authors concluded that these nationally recommended interventions prevented a high proportion of CVD, but most of them substantially increased the health care costs. The methodology was appropriate and the results were described

NHS Economic Evaluation Database.2008