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Latest & greatest articles for cardiovascular disease
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on cardiovascular disease or other clinical topics then use Trip today.
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Achieving best outcomes for patients with cardiovasculardisease in China by enhancing the quality of medical care and establishing a learning health-care system. China has an immediate need to address the rapidly growing population with cardiovasculardisease events and the increasing number of people living with this illness. Despite progress in increasing access to services, China faces the dual challenge of addressing gaps in quality of care and producing more evidence to support clinical (...) practice. In this Review, we address opportunities to strengthen performance measurement, programmes to improve quality of care, and national capacity to produce high-impact knowledge for clinical practice. Moreover, we propose recommendations, with implications for other diseases, for how China can immediately make use of its Hospital Quality-Monitoring System and other existing national platforms to assess and improve performance of medical care, and to generate new knowledge to inform clinical
Vitamin K for the primary prevention of cardiovasculardisease. BACKGROUND: A deficiency in vitamin K has been associated with increased calcium deposition and coronary artery calcification, which may lead to cardiovasculardisease. OBJECTIVES: To determine the effectiveness of vitamin K supplementation as a single nutrient supplement for the primary prevention of cardiovasculardisease. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled (...) and reference lists of reviews for further studies. We applied no language restrictions. SELECTION CRITERIA: We included randomised controlled trials of vitamin K supplementation as a single nutrient supplement, lasting at least three months, and involving healthy adults or adults at high risk of cardiovasculardisease. The comparison group was no intervention or placebo. The outcomes of interest were cardiovasculardisease clinical events and cardiovasculardisease risk factors. DATA COLLECTION
Alcohol consumption and cardiovasculardisease, cancer, injury, admission to hospital, and mortality: a prospective cohort study. BACKGROUND: Alcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort (...) of countries at different economic levels in five continents. METHODS: We included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovasculardisease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786
A prospective multicentre study on the treatment of cardiovascular risk factors and claudication symptoms in patients with peripheral artery disease (the IDOMENEO study). 26317257 2015 08 31 2015 10 27 2015 08 31 0301-1526 44 5 2015 Sep VASA. Zeitschrift fur Gefasskrankheiten VASA A prospective multicentre study on the treatment of cardiovascular risk factors and claudication symptoms in patients with peripheral artery disease (the IDOMENEO study). 371-9 10.1024/0301-1526/a000456 The objective (...) of this prospective multicenter cohort study was to characterise the use of pharmacological and non-pharmacological treatment for cardiovasculardisease (CVD) risk factors and intermittent claudication (IC) symptoms in clinical practice patients with peripheral artery disease (PAD), and to determine the care gap with international guidelines and evidence-based therapy. From 2011 through 2013, participating centres enrolled consecutive patients with PAD of atherosclerotic, origin demonstrated by ultrasound, ankle
Prognostic Value of Stress Echocardiography in Patients With Low-Intermediate or High Short-Term (10 Years) Versus Low (=39%) or High (>/=39%) Lifetime Predicted Risk of CardiovascularDisease According to the American College of Cardiology/American Hea 26138377 2015 08 15 2015 11 10 2016 11 25 1879-1913 116 5 2015 Sep 01 The American journal of cardiology Am. J. Cardiol. Prognostic Value of Stress Echocardiography in Patients With Low-Intermediate or High Short-Term (10 Years) Versus Low (...) (<39%) or High (≥39%) Lifetime Predicted Risk of CardiovascularDisease According to the American College of Cardiology/American Heart Association 2013 Cardiovascular Risk Calculator. 725-9 10.1016/j.amjcard.2015.05.040 S0002-9149(15)01424-1 This study evaluates the prognostic value of stress echocardiography (Secho) in short-term (10 years) and lifetime atherosclerotic cardiovasculardisease risk-defined groups according to the American College of Cardiology/American Heart Association 2013
Qigong for the primary prevention of cardiovasculardisease. BACKGROUND: Two major determinants of cardiovasculardisease (CVD) are a sedentary lifestyle and stress. Qigong involves physical exercise, mind regulation and breathing control to restore the flow of Qi (a pivotal life energy). As it is thought to help reduce stress and involves exercise, qigong may be an effective strategy for the primary prevention of CVD. OBJECTIVES: To determine the effectiveness of qigong for the primary
Cangrelor (Kengraxel) - for the reduction of thrombotic cardiovascular events in adult patients with coronary artery disease undergoing percutaneous coronary intervention Published 08 June 2015 Statement of Advice cangrelor (Kengrexal ® ) SMC No. (1070/15) The Medicines Company 08 May 2015 ADVICE: in the absence of a submission from the holder of the marketing authorisation cangrelor (Kengrexal ® ) is not recommended for use within NHS Scotland. Indication under review: Co-administered (...) with acetylsalicylic acid for the reduction of thrombotic cardiovascular events in adult patients with coronary artery disease undergoing percutaneous coronary intervention who have not received an oral P2Y12 inhibitor prior to the PCI procedure and in whom oral therapy with P2Y12 inhibitors is not feasible or desirable. The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland. Advice context
The prognostic utility of tests of platelet function for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation The prognostic and diagnostic utility of tests of platelet function for the detection of "aspirin resistance" in patients with established cardiovascular or cerebrovascular disease: A systematic review and economic evaluation Journals Library An error has occurred in processing the XML
The Dietary Approaches to Stop Hypertension (DASH) Diet Has Been Proven to Lower Blood Pressure and Is a Feasible Approach to Lessen Dental Complications in Patients With Hypertension and CardiovascularDisease UTCAT2842, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Dietary Approaches to Stop Hypertension (DASH) Diet Has Been Proven to Lower Blood Pressure and Is a Feasible Approach to Lessen Dental (...) Complications in Patients With Hypertension and CardiovascularDisease Clinical Question In dental patients with longstanding hypertension, how effective is the DASH diet at lowering blood pressure? Clinical Bottom Line The Dietary Approaches to Stop Hypertension (DASH) diet has been shown to reduce blood pressure. Reducing blood pressure may lessen the risk of complications for patients with hypertension and cardiovascular-associated diseases during dental treatment. Best Evidence (you may view more info
Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovasculardisease in diabetes. BACKGROUND: Enhanced complement C3 incorporation into the fibrin network in diabetes is one mechanism for impaired fibrinolysis and increased thrombosis risk in this condition. Our aim was to develop new strategies to modulate fibrinolysis in diabetes by interfering with fibrin-C3 interaction. METHODS: To modulate interaction between fibrinogen and C3 we
Type 2 diabetes and incidence of a wide range of cardiovasculardiseases: a cohort study in 1·9 million people. BACKGROUND: The contemporary associations of type 2 diabetes with a wide range of incident cardiovasculardiseases have not been compared. Previous studies have focussed on myocardial infarction and stroke, and these conditions are the usual outcomes chosen in clinical trials in type 2 diabetes, but other diseases such as heart failure and angina are also major causes of morbidity (...) in diabetes. We aimed to study associations between type 2 diabetes and 12 initial manifestations of cardiovasculardisease. METHODS: We used linked electronic health records from 1997 to 2010 in the CALIBER (cardiovascular research using linked bespoke studies and electronic health records) programme to investigate the absolute and relative risks associated with type 2 diabetes in a cohort of 1·92 million patients in England. We included patients aged 30 years and older who were free from cardiovascular
Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovasculardisease. OBJECTIVE: To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. DESIGN: Cluster randomised controlled trial. SETTING: 36 general practices in the north west of England. PARTICIPANTS: 387 patients (...) with a record of diabetes or heart disease, or both, who had depressive symptoms (≥ 10 on patient health questionaire-9 (PHQ-9)) for at least two weeks. Mean age was 58.5 (SD 11.7). Participants reported a mean of 6.2 (SD 3.0) long term conditions other than diabetes or heart disease; 240 (62%) were men; 360 (90%) completed the trial. INTERVENTIONS: Collaborative care included patient preference for behavioural activation, cognitive restructuring, graded exposure, and/or lifestyle advice, management of drug
Risk factors for cardiovasculardisease in people with idiopathic pulmonary fibrosis: a population-based study 25121965 2015 01 06 2015 03 10 2016 11 25 1931-3543 147 1 2015 Jan Chest Chest Risk factors for cardiovasculardisease in people with idiopathic pulmonary fibrosis: a population-based study. 150-6 10.1378/chest.14-0041 People with idiopathic pulmonary fibrosis (IPF) have been shown to be at an increased risk for cardiovascular (CV) disease, but reasons for this are unknown. The aim (...) Vidya V eng Department of Health United Kingdom Comparative Study Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States Chest 0231335 0012-3692 AIM IM Aged CardiovascularDiseases epidemiology etiology Female Follow-Up Studies Humans Idiopathic Pulmonary Fibrosis complications epidemiology Incidence Male Population Surveillance Prevalence Retrospective Studies Risk Assessment methods Risk Factors United Kingdom epidemiology 2014 8 15 6 0 2014 8 15 6 0 2015 3 11 6 0
Association between hospitalization for pneumonia and subsequent risk of cardiovasculardisease. IMPORTANCE: The risk of cardiovasculardisease (CVD) after infection is poorly understood. OBJECTIVE: To determine whether hospitalization for pneumonia is associated with an increased short-term and long-term risk of CVD. DESIGN, SETTINGS, AND PARTICIPANTS: We examined 2 community-based cohorts: the Cardiovascular Health Study (CHS, n = 5888; enrollment age, ≥65 years; enrollment period, 1989-1994 (...) . EXPOSURES: Hospitalization for pneumonia. MAIN OUTCOMES AND MEASURES: Incident CVD (myocardial infarction, stroke, and fatal coronary heart disease). RESULTS: Of 591 pneumonia cases in CHS, 206 had CVD events over 10 years after pneumonia hospitalization. CVD risk after pneumonia was highest in the first year. CVD occurred in 54 cases and 6 controls in the first 30 days (HR, 4.07; 95% CI, 2.86-5.27); 11 cases and 9 controls between 31 and 90 days (HR, 2.94; 95% CI, 2.18-3.70); and 22 cases and 55
Community-wide cardiovasculardisease prevention programs and health outcomes in a rural county, 1970-2010. IMPORTANCE: Few comprehensive cardiovascular risk reduction programs, particularly those in rural, low-income communities, have sustained community-wide interventions for more than 10 years and demonstrated the effect of risk factor improvements on reductions in morbidity and mortality. OBJECTIVE: To document health outcomes associated with an integrated, comprehensive cardiovascular risk (...) community organizations, including the local hospital and clinicians. MAIN OUTCOMES AND MEASURES: Resident participation; hypertension and hyperlipidemia detection, treatment, and control; smoking quit rates; hospitalization rates from 1994 through 2006, adjusted for median household income; and mortality rates from 1970 through 2010, adjusted for household income and age. RESULTS: More than 150,000 individual county resident contacts occurred over 40 years. Over time, as cardiovascular risk factor
A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovasculardisease achieves significant but small improvements over usual care in depression and patient satisfaction A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovasculardisease achieves significant but small improvements over usual care in depression and patient satisfaction | Evidence-Based Mental Health This site uses (...) to patients with depression comorbid with diabetes or cardiovasculardisease achieves significant but small improvements over usual care in depression and patient satisfaction Article Text Psychological interventions A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovasculardisease achieves significant but small improvements over usual care in depression and patient satisfaction Michael Sharpe Statistics from Altmetric.com No Altmetric data