Latest & greatest articles for cardiovascular disease

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on cardiovascular disease or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on cardiovascular disease and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for cardiovascular disease

241. Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system.

Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system. China has an immediate need to address the rapidly growing population with cardiovascular disease events and the increasing number of people living with this illness. Despite progress in increasing access to services, China faces the dual challenge of addressing gaps in quality of care and producing more evidence to support clinical (...) practice. In this Review, we address opportunities to strengthen performance measurement, programmes to improve quality of care, and national capacity to produce high-impact knowledge for clinical practice. Moreover, we propose recommendations, with implications for other diseases, for how China can immediately make use of its Hospital Quality-Monitoring System and other existing national platforms to assess and improve performance of medical care, and to generate new knowledge to inform clinical

Lancet2015

242. Increased risk of cardiovascular disease in giant cell arteritis: a general population-based study

Increased risk of cardiovascular disease in giant cell arteritis: a general population-based study 26248811 2015 12 15 2016 04 07 2015 12 15 1462-0332 55 1 2016 Jan Rheumatology (Oxford, England) Rheumatology (Oxford) Increased risk of cardiovascular disease in giant cell arteritis: a general population-based study. 33-40 10.1093/rheumatology/kev262 To determine the risk of newly recorded myocardial infarction (MI) and stroke among incident GCA cases compared with controls from the general (...) provide general population-based evidence that GCA patients are at a substantially increased risk of cardiovascular disease. Increased monitoring for this potentially fatal outcome and its modifiable risk factors is warranted for GCA patients. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com. Amiri Neda N Division of Rheumatology, Department of Medicine, University

EvidenceUpdates2015

243. The relationship between psychosocial risk factors and health outcomes of chronic diseases: a review of the evidence for cancer and cardiovascular diseases

The relationship between psychosocial risk factors and health outcomes of chronic diseases: a review of the evidence for cancer and cardiovascular diseases

WHO Health Evidence Network2015

245. Vitamin K for the primary prevention of cardiovascular disease.

Vitamin K for the primary prevention of cardiovascular disease. BACKGROUND: A deficiency in vitamin K has been associated with increased calcium deposition and coronary artery calcification, which may lead to cardiovascular disease. OBJECTIVES: To determine the effectiveness of vitamin K supplementation as a single nutrient supplement for the primary prevention of cardiovascular disease. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled (...) and reference lists of reviews for further studies. We applied no language restrictions. SELECTION CRITERIA: We included randomised controlled trials of vitamin K supplementation as a single nutrient supplement, lasting at least three months, and involving healthy adults or adults at high risk of cardiovascular disease. The comparison group was no intervention or placebo. The outcomes of interest were cardiovascular disease clinical events and cardiovascular disease risk factors. DATA COLLECTION

Cochrane2015

246. Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.

Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study. BACKGROUND: Alcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort (...) of countries at different economic levels in five continents. METHODS: We included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovascular disease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786

Lancet2015

247. A prospective multicentre study on the treatment of cardiovascular risk factors and claudication symptoms in patients with peripheral artery disease (the IDOMENEO study).

A prospective multicentre study on the treatment of cardiovascular risk factors and claudication symptoms in patients with peripheral artery disease (the IDOMENEO study). 26317257 2015 08 31 2015 10 27 2015 08 31 0301-1526 44 5 2015 Sep VASA. Zeitschrift fur Gefasskrankheiten VASA A prospective multicentre study on the treatment of cardiovascular risk factors and claudication symptoms in patients with peripheral artery disease (the IDOMENEO study). 371-9 10.1024/0301-1526/a000456 The objective (...) of this prospective multicenter cohort study was to characterise the use of pharmacological and non-pharmacological treatment for cardiovascular disease (CVD) risk factors and intermittent claudication (IC) symptoms in clinical practice patients with peripheral artery disease (PAD), and to determine the care gap with international guidelines and evidence-based therapy. From 2011 through 2013, participating centres enrolled consecutive patients with PAD of atherosclerotic, origin demonstrated by ultrasound, ankle

VASA. Zeitschrift fur Gefasskrankheiten2015

248. Prognostic Value of Stress Echocardiography in Patients With Low-Intermediate or High Short-Term (10 Years) Versus Low (</=39%) or High (>/=39%) Lifetime Predicted Risk of Cardiovascular Disease According to the American College of Cardiology/American Hea

Prognostic Value of Stress Echocardiography in Patients With Low-Intermediate or High Short-Term (10 Years) Versus Low (/=39%) Lifetime Predicted Risk of Cardiovascular Disease According to the American College of Cardiology/American Hea 26138377 2015 08 15 2015 11 10 2016 11 25 1879-1913 116 5 2015 Sep 01 The American journal of cardiology Am. J. Cardiol. Prognostic Value of Stress Echocardiography in Patients With Low-Intermediate or High Short-Term (10 Years) Versus Low (...) (<39%) or High (≥39%) Lifetime Predicted Risk of Cardiovascular Disease According to the American College of Cardiology/American Heart Association 2013 Cardiovascular Risk Calculator. 725-9 10.1016/j.amjcard.2015.05.040 S0002-9149(15)01424-1 This study evaluates the prognostic value of stress echocardiography (Secho) in short-term (10 years) and lifetime atherosclerotic cardiovascular disease risk-defined groups according to the American College of Cardiology/American Heart Association 2013

EvidenceUpdates2015

249. Qigong for the primary prevention of cardiovascular disease.

Qigong for the primary prevention of cardiovascular disease. BACKGROUND: Two major determinants of cardiovascular disease (CVD) are a sedentary lifestyle and stress. Qigong involves physical exercise, mind regulation and breathing control to restore the flow of Qi (a pivotal life energy). As it is thought to help reduce stress and involves exercise, qigong may be an effective strategy for the primary prevention of CVD. OBJECTIVES: To determine the effectiveness of qigong for the primary

Cochrane2015

250. Cangrelor (Kengraxel) - for the reduction of thrombotic cardiovascular events in adult patients with coronary artery disease undergoing percutaneous coronary intervention

Cangrelor (Kengraxel) - for the reduction of thrombotic cardiovascular events in adult patients with coronary artery disease undergoing percutaneous coronary intervention Published 08 June 2015 Statement of Advice cangrelor (Kengrexal ® ) SMC No. (1070/15) The Medicines Company 08 May 2015 ADVICE: in the absence of a submission from the holder of the marketing authorisation cangrelor (Kengrexal ® ) is not recommended for use within NHS Scotland. Indication under review: Co-administered (...) with acetylsalicylic acid for the reduction of thrombotic cardiovascular events in adult patients with coronary artery disease undergoing percutaneous coronary intervention who have not received an oral P2Y12 inhibitor prior to the PCI procedure and in whom oral therapy with P2Y12 inhibitors is not feasible or desirable. The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland. Advice context

Scottish Medicines Consortium2015

251. The prognostic utility of tests of platelet function for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation

The prognostic utility of tests of platelet function for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation The prognostic and diagnostic utility of tests of platelet function for the detection of "aspirin resistance" in patients with established cardiovascular or cerebrovascular disease: A systematic review and economic evaluation Journals Library An error has occurred in processing the XML

NIHR HTA programme2015

252. The Dietary Approaches to Stop Hypertension (DASH) Diet Has Been Proven to Lower Blood Pressure and Is a Feasible Approach to Lessen Dental Complications in Patients With Hypertension and Cardiovascular Disease

The Dietary Approaches to Stop Hypertension (DASH) Diet Has Been Proven to Lower Blood Pressure and Is a Feasible Approach to Lessen Dental Complications in Patients With Hypertension and Cardiovascular Disease UTCAT2842, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Dietary Approaches to Stop Hypertension (DASH) Diet Has Been Proven to Lower Blood Pressure and Is a Feasible Approach to Lessen Dental (...) Complications in Patients With Hypertension and Cardiovascular Disease Clinical Question In dental patients with longstanding hypertension, how effective is the DASH diet at lowering blood pressure? Clinical Bottom Line The Dietary Approaches to Stop Hypertension (DASH) diet has been shown to reduce blood pressure. Reducing blood pressure may lessen the risk of complications for patients with hypertension and cardiovascular-associated diseases during dental treatment. Best Evidence (you may view more info

UTHSCSA Dental School CAT Library2015

253. Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes.

Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes. BACKGROUND: Enhanced complement C3 incorporation into the fibrin network in diabetes is one mechanism for impaired fibrinolysis and increased thrombosis risk in this condition. Our aim was to develop new strategies to modulate fibrinolysis in diabetes by interfering with fibrin-C3 interaction. METHODS: To modulate interaction between fibrinogen and C3 we

Lancet2015

254. Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people.

Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people. BACKGROUND: The contemporary associations of type 2 diabetes with a wide range of incident cardiovascular diseases have not been compared. Previous studies have focussed on myocardial infarction and stroke, and these conditions are the usual outcomes chosen in clinical trials in type 2 diabetes, but other diseases such as heart failure and angina are also major causes of morbidity (...) in diabetes. We aimed to study associations between type 2 diabetes and 12 initial manifestations of cardiovascular disease. METHODS: We used linked electronic health records from 1997 to 2010 in the CALIBER (cardiovascular research using linked bespoke studies and electronic health records) programme to investigate the absolute and relative risks associated with type 2 diabetes in a cohort of 1·92 million patients in England. We included patients aged 30 years and older who were free from cardiovascular

Lancet2015

255. Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease.

Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease. OBJECTIVE: To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. DESIGN: Cluster randomised controlled trial. SETTING: 36 general practices in the north west of England. PARTICIPANTS: 387 patients (...) with a record of diabetes or heart disease, or both, who had depressive symptoms (≥ 10 on patient health questionaire-9 (PHQ-9)) for at least two weeks. Mean age was 58.5 (SD 11.7). Participants reported a mean of 6.2 (SD 3.0) long term conditions other than diabetes or heart disease; 240 (62%) were men; 360 (90%) completed the trial. INTERVENTIONS: Collaborative care included patient preference for behavioural activation, cognitive restructuring, graded exposure, and/or lifestyle advice, management of drug

BMJ2015 Full Text: Link to full Text with Trip Pro

256. Risk factors for cardiovascular disease in people with idiopathic pulmonary fibrosis: a population-based study

Risk factors for cardiovascular disease in people with idiopathic pulmonary fibrosis: a population-based study 25121965 2015 01 06 2015 03 10 2016 11 25 1931-3543 147 1 2015 Jan Chest Chest Risk factors for cardiovascular disease in people with idiopathic pulmonary fibrosis: a population-based study. 150-6 10.1378/chest.14-0041 People with idiopathic pulmonary fibrosis (IPF) have been shown to be at an increased risk for cardiovascular (CV) disease, but reasons for this are unknown. The aim (...) Vidya V eng Department of Health United Kingdom Comparative Study Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States Chest 0231335 0012-3692 AIM IM Aged Cardiovascular Diseases epidemiology etiology Female Follow-Up Studies Humans Idiopathic Pulmonary Fibrosis complications epidemiology Incidence Male Population Surveillance Prevalence Retrospective Studies Risk Assessment methods Risk Factors United Kingdom epidemiology 2014 8 15 6 0 2014 8 15 6 0 2015 3 11 6 0

EvidenceUpdates2015

257. Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults

Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults 25251676 2014 11 18 2015 09 16 2014 11 18 1930-739X 22 12 2014 Dec Obesity (Silver Spring, Md.) Obesity (Silver Spring) Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults. 2524-31 10.1002/oby.20909 Alternate day fasting (ADF; 24-h feeding/24-h 25% energy intake at lunchtime), is effective for weight loss, but diet (...) ;23(4):914 Adult Body Weight Cardiovascular Diseases prevention & control Diet, Reducing methods Fasting physiology Female Humans Male Middle Aged Obesity diet therapy Risk Factors Weight Loss 2014 07 07 2014 08 30 2014 9 25 6 0 2014 9 25 6 0 2015 9 17 6 0 ppublish 25251676 10.1002/oby.20909

EvidenceUpdates2015

258. Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease.

Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease. IMPORTANCE: The risk of cardiovascular disease (CVD) after infection is poorly understood. OBJECTIVE: To determine whether hospitalization for pneumonia is associated with an increased short-term and long-term risk of CVD. DESIGN, SETTINGS, AND PARTICIPANTS: We examined 2 community-based cohorts: the Cardiovascular Health Study (CHS, n = 5888; enrollment age, ≥65 years; enrollment period, 1989-1994 (...) . EXPOSURES: Hospitalization for pneumonia. MAIN OUTCOMES AND MEASURES: Incident CVD (myocardial infarction, stroke, and fatal coronary heart disease). RESULTS: Of 591 pneumonia cases in CHS, 206 had CVD events over 10 years after pneumonia hospitalization. CVD risk after pneumonia was highest in the first year. CVD occurred in 54 cases and 6 controls in the first 30 days (HR, 4.07; 95% CI, 2.86-5.27); 11 cases and 9 controls between 31 and 90 days (HR, 2.94; 95% CI, 2.18-3.70); and 22 cases and 55

JAMA2015

259. Community-wide cardiovascular disease prevention programs and health outcomes in a rural county, 1970-2010.

Community-wide cardiovascular disease prevention programs and health outcomes in a rural county, 1970-2010. IMPORTANCE: Few comprehensive cardiovascular risk reduction programs, particularly those in rural, low-income communities, have sustained community-wide interventions for more than 10 years and demonstrated the effect of risk factor improvements on reductions in morbidity and mortality. OBJECTIVE: To document health outcomes associated with an integrated, comprehensive cardiovascular risk (...) community organizations, including the local hospital and clinicians. MAIN OUTCOMES AND MEASURES: Resident participation; hypertension and hyperlipidemia detection, treatment, and control; smoking quit rates; hospitalization rates from 1994 through 2006, adjusted for median household income; and mortality rates from 1970 through 2010, adjusted for household income and age. RESULTS: More than 150,000 individual county resident contacts occurred over 40 years. Over time, as cardiovascular risk factor

JAMA2015

260. A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovascular disease achieves significant but small improvements over usual care in depression and patient satisfaction

A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovascular disease achieves significant but small improvements over usual care in depression and patient satisfaction A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovascular disease achieves significant but small improvements over usual care in depression and patient satisfaction | Evidence-Based Mental Health This site uses (...) to patients with depression comorbid with diabetes or cardiovascular disease achieves significant but small improvements over usual care in depression and patient satisfaction Article Text Psychological interventions A collaborative care approach delivering treatment to patients with depression comorbid with diabetes or cardiovascular disease achieves significant but small improvements over usual care in depression and patient satisfaction Michael Sharpe Statistics from Altmetric.com No Altmetric data

Evidence-Based Mental Health2015