Latest & greatest articles for cancer

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Top results for cancer

8621. Preoperative radiotherapy for resectable rectal cancer: a meta-analysis

Preoperative radiotherapy for resectable rectal cancer: a meta-analysis Preoperative radiotherapy for resectable rectal cancer: a meta-analysis Preoperative radiotherapy for resectable rectal cancer: a meta-analysis Camma C, Giunta M, Fiorica F, Pagliaro L, Craxi A, Cottone M Authors' objectives To assess the effectiveness of preoperative radiotherapy followed by surgery in the reduction of overall and cancer-related mortality and the prevention of local recurrences and distant metastases (...) in patients with resectable rectal cancer. Searching Peer-reviewed reports were sought in MEDLINE and Cancerlit (from inception through December 1999) using the following medical subject headings: 'rectal cancer'; 'radiotherapy'; 'surgery'; 'RCT'; 'randomized'; and 'clinical trial'. Handsearches were conducted of reference lists for all available review articles, primary studies, abstracts from meetings, and bibliographies of books. Non-English publications were eligible. Study selection Study designs

DARE.2000

8622. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials.

Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Prostate Cancer Trialists' Collaborative Group Authors' objectives To determine the effect on survival of maximum androgen blockade (MAB) compared with androgen suppression (AS) alone. Searching Electronic databases (...) , trial registers, meeting abstracts and reference lists were searched. Investigators, trial groups and pharmaceutical companies were contacted (see Other Publications of Related Interest no.1). A secretariat and collaborative group (The Prostate Cancer Trialists' Collaborative Group) was established to identify trials and undertake the meta-analysis. Study selection Study designs of evaluations included in the review The review included individual patient data (IPD) from randomised controlled trials

DARE.2000

8623. Effectiveness of interventions to improve follow-up after abnormal cervical cancer screening

Effectiveness of interventions to improve follow-up after abnormal cervical cancer screening Effectiveness of interventions to improve follow-up after abnormal cervical cancer screening Effectiveness of interventions to improve follow-up after abnormal cervical cancer screening Yabroff K R, Kerner J F, Mandelblatt J S Authors' objectives To determine the effectiveness of interventions designed to improve follow-up after an abnormal Pap smear. Searching MEDLINE was searched from 1980 to 1999 (...) using the terms 'colposcopy', 'vaginal smears', 'cervix neoplasms', 'cervix dysplasia' combined with 'patient education', 'patient acceptance of healthcare' and 'patient compliance'. Inclusion was restricted to publications in the English language; published abstracts, review articles and letters were excluded. The reference lists of studies that met the inclusion criteria were examined, and issues of Medical Care, Preventive Medicine, American Journal of Preventive Medicine, Obstetrics

DARE.2000

8624. A rapid and systematic review of the effectiveness and cost-effectiveness of the taxanes used in the treatment of advanced breast and ovarian cancer

A rapid and systematic review of the effectiveness and cost-effectiveness of the taxanes used in the treatment of advanced breast and ovarian cancer A rapid and systematic review of the effectiveness and cost-effectiveness of the taxanes used in the treatment of advanced breast and ovarian cancer A rapid and systematic review of the effectiveness and cost-effectiveness of the taxanes used in the treatment of advanced breast and ovarian cancer Lister-Sharp D, McDonagh M S, Khan K S, Kleijnen J (...) Authors' objectives To evaluate the effectiveness and cost-effectiveness of: 1. Paclitaxel (taxol) and docetaxel (taxotere) as first- and second-line treatment of advanced breast cancer. 2. Paclitaxel as first-line treatment of ovarian cancer. Searching MEDLINE, EMBASE, Cancerlit, the Cochrane Controlled Trials Register and the National Research Register (NRR) were searched. The search terms used were presented in the appendix but no dates were given. The review was conducted on behalf of the UK

DARE.2000

8625. Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels

Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels Hoffman R M, Clanon D L, Littenberg B (...) , Frank J J, Peirce J C Authors' objectives To determine whether the free-to-total prostate-specific antigen (PSA) ratio improved the diagnostic accuracy of non-specific PSA results. Searching MEDLINE was searched from January 1986 to July 1997 for publications in the English language. The search used a combination of the MeSH terms 'prostate-specific antigen' and 'prostatic neoplasm' and then linked them with 'alpha-1-antichymotrypsin' or with 'free' or 'gamma-semiprotein'. The bibliographies

DARE.2000

8626. Physical activity in the primary prevention of estrogen-related cancers: is it effective?

Physical activity in the primary prevention of estrogen-related cancers: is it effective? Physical activity in the primary prevention of estrogen-related cancers: is it effective? Physical activity in the primary prevention of estrogen-related cancers: is it effective? Campbell K L, Harris S R Authors' objectives To examine the influence of exercise, or physical activity in general, on the risk for oestrogen-related cancers. Searching MEDLINE and CINAHL were searched from 1985 to August 1998 (...) using the following terms: 'breast cancer', 'physical activity', 'exercise', 'estrogen-related cancers'. The search was restricted to publications in the English language. The reference lists from previously identified research articles were also used to locate additional references. Study selection Study designs of evaluations included in the review Prospective cohort, retrospective cohort, case-control, and 'record-linkage' studies were included. Specific interventions included in the review

DARE.2000

8627. Pilocarpine for radiation-induced xerostomia in head and neck cancer

Pilocarpine for radiation-induced xerostomia in head and neck cancer Pilocarpine for radiation-induced xerostomia in head and neck cancer Pilocarpine for radiation-induced xerostomia in head and neck cancer Hawthorne M, Sullivan K Authors' objectives To examine the use of pilocarpine hydrochloride for radiation-induced xerostomia in patients with head and neck cancer. Searching The following databases were searched for studies published in the English language: MEDLINE from 1966 to 1999; CINAHL (...) pilocarpine. Topical pilocarpine was used as a mouthwash. Systemic pilocarpine was used in doses ranging from 2.5 to 10 mg, three times a day. Participants included in the review Head and neck cancer patients with post-radiation xerostomia of at least 2 months' duration. Studies using pilocarpine for xerostomia in patients with advanced cancer and other medical conditions, not necessarily radiation-induced xerostomia, were excluded. Where given, the participants' ages ranged from 16 to 82 years. Outcomes

DARE.2000

8628. Cost-effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus-negative homosexual and bisexual men

Cost-effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus-negative homosexual and bisexual men Cost-effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus-negative homosexual and bisexual men Cost-effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus-negative homosexual and bisexual men Goldie S J, Kuntz K M (...) , Weinstein M C, Freedberg K A, Palefsky J M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Screening, diagnosis and treatment of anal squamous intraepithelial lesions (ASIL) and anal cancer in HIV-negative homosexual and bisexual men

NHS Economic Evaluation Database.2000

8629. Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate

Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate Dranitsaris G, Leung P, Mather J, Oza A Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of two aromatase inhibitors, letrozole (LET, 2.5 mg/day) and anastrozole (ANA, 1 mg/day), as second-line therapy for women with breast cancer who did not respond to tamoxifen. Type of intervention

NHS Economic Evaluation Database.2000

8630. Hysterectomy for obese women with endometrial cancer: laparoscopy or laparotomy?

Hysterectomy for obese women with endometrial cancer: laparoscopy or laparotomy? Hysterectomy for obese women with endometrial cancer: laparoscopy or laparotomy? Hysterectomy for obese women with endometrial cancer: laparoscopy or laparotomy? Eltabbakh G H, Shamonki M I, Moody J M, Garafano L L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of laparoscopy versus laparotomy for vaginal hysterectomy. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised obese women with clinical stage I endometrial cancer or uterine sarcoma, and body mass indices (BMIs) between 28.0 and 60.0. Setting The setting was secondary care (gynaecologic oncology unit

NHS Economic Evaluation Database.2000

8631. A cost-outcome analysis of adjuvant postmastectomy locoregional radiotherapy in premenopausal node-positive breast cancer patients

A cost-outcome analysis of adjuvant postmastectomy locoregional radiotherapy in premenopausal node-positive breast cancer patients A cost-outcome analysis of adjuvant postmastectomy locoregional radiotherapy in premenopausal node-positive breast cancer patients A cost-outcome analysis of adjuvant postmastectomy locoregional radiotherapy in premenopausal node-positive breast cancer patients Dunscombe P, Samant R, Roberts G Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of adjuvant, postmastectomy, locoregional radiotherapy for lymph-node-positive breast cancer. The intervention delivered radiotherapy to the chest wall and adjacent lymph-node regions with a 4-field technique. Type of intervention Treatment

NHS Economic Evaluation Database.2000

8632. The cost-effectiveness and cost-utility of high-dose palliative radiotherapy for advanced non-small-cell lung cancer

The cost-effectiveness and cost-utility of high-dose palliative radiotherapy for advanced non-small-cell lung cancer The cost-effectiveness and cost-utility of high-dose palliative radiotherapy for advanced non-small-cell lung cancer The cost-effectiveness and cost-utility of high-dose palliative radiotherapy for advanced non-small-cell lung cancer Coy P, Schaafsma J, Schofield J A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS (...) EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of high-dose palliative radiotherapy (RT) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC). Type of intervention Palliative care. Economic study type Cost-effectiveness and cost-utility analyses. Study population The study population comprised patients

NHS Economic Evaluation Database.2000

8633. Cost-effectiveness of androgen suppression therapies in advanced prostate cancer

Cost-effectiveness of androgen suppression therapies in advanced prostate cancer Cost-effectiveness of androgen suppression therapies in advanced prostate cancer Cost-effectiveness of androgen suppression therapies in advanced prostate cancer Bayoumi A M, Brown A D, Garber A M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Six androgen suppression therapies for advanced prostate cancer were examined. These were diethylstilbestrol (DES), bilateral orchiectomy, a nonsteroidal antiandrogen (NSAA; nilutamide), a luteinising hormone-releasing hormone (LHRH) agonist (goserelin), and two combined androgen blockade strategies (NSAA with a LHRH agonist, and NSAA with orchiectomy). Type of intervention Palliative care

NHS Economic Evaluation Database.2000

8634. Randomized trial of a specialist genetic assessment service for familial breast cancer

Randomized trial of a specialist genetic assessment service for familial breast cancer Randomized trial of a specialist genetic assessment service for familial breast cancer Randomized trial of a specialist genetic assessment service for familial breast cancer Brain K, Gray J, Norman P, France E, Anglim C, Barton G, Parsons E, Clarke A, Sweetland H, Tischkowitz M, Myring J, Stansfield K, Webster D, Gower-Thomas K, Daoud R, Gateley C, Monypenny I, Singhal H, Branston L, Sampson J, Roberts E (...) , Newcombe R, Cohen D, Rogers C, Mansel R, Harper P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of a new multidisciplinary genetic and surgical assessment service for screening for breast cancer, in women with a family

NHS Economic Evaluation Database.2000

8635. Could chest X-ray screening for lung cancer be cost-effective?

Could chest X-ray screening for lung cancer be cost-effective? Could chest X-ray screening for lung cancer be cost-effective? Could chest X-ray screening for lung cancer be cost-effective? Caro J J, Klittich W S, Strauss G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study (...) and the conclusions drawn. Health technology A programme of annual chest X-ray screening for lung cancer was examined in male smokers. Type of intervention Screening. Economic study type Cost-effectiveness analysis. Study population The study population comprised male smokers aged 45 to 80 years. Setting The setting of the clinical study was unclear (chest X-ray screening could be performed in primary or secondary care). The economic study was performed in Massachusetts, USA. Dates to which data relate

NHS Economic Evaluation Database.2000

8636. Decision framework for chemotherapeutic interventions for metastatic non-small-cell lung cancer

Decision framework for chemotherapeutic interventions for metastatic non-small-cell lung cancer Decision framework for chemotherapeutic interventions for metastatic non-small-cell lung cancer Decision framework for chemotherapeutic interventions for metastatic non-small-cell lung cancer Berthelot J M, Will B P, Evans W K, Coyle D, Earle C C, Bordeleau L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains (...) a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Nine chemotherapy regimens to palliate cancer-related symptoms and modestly improve survival were considered: vindesine plus cisplatin (VDS+P), etoposide plus cisplatin (VP-16+P), vinblastine plus cisplatin (VLB+P), vinorelbine plus cisplatin (NVB+P), paclitaxel 135 mg/m2 plus cisplatin (T+P 135 mg/m2), paclitaxel 200 mg/m2

NHS Economic Evaluation Database.2000

8637. Cost-effectiveness analysis of immunochemical occult blood screening for colorectal cancer among three fecal sampling methods

Cost-effectiveness analysis of immunochemical occult blood screening for colorectal cancer among three fecal sampling methods Cost-effectiveness analysis of immunochemical occult blood screening for colorectal cancer among three fecal sampling methods Cost-effectiveness analysis of immunochemical occult blood screening for colorectal cancer among three fecal sampling methods Yamamoto M, Nakama H Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Immunochemical occult blood screening for colorectal cancer using three different fecal sampling methods followed by a diagnostic examination (colonoscopy) for positive test results. Each participant provided fecal samples on three consecutive days. The first screening method

NHS Economic Evaluation Database.2000

8638. Cost-effectiveness of second-line treatment with irinotecan or infusional 5-fluorouracil in metastatic colorectal cancer

Cost-effectiveness of second-line treatment with irinotecan or infusional 5-fluorouracil in metastatic colorectal cancer Cost-effectiveness of second-line treatment with irinotecan or infusional 5-fluorouracil in metastatic colorectal cancer Cost-effectiveness of second-line treatment with irinotecan or infusional 5-fluorouracil in metastatic colorectal cancer Levy-Piedbois C, Durand-Zaleski I, Juhel H, Schmitt C, Bellanger A, Piedbois P Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Irinotecan was compared to infusional 5-fluorouracil (5-FU) as second-line treatment for patients with metastatic colorectal cancer. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study

NHS Economic Evaluation Database.2000

8639. Pamidronate in prevention of bone complications in metastatic breast cancer: a cost-effectiveness analysis

Pamidronate in prevention of bone complications in metastatic breast cancer: a cost-effectiveness analysis Pamidronate in prevention of bone complications in metastatic breast cancer: a cost-effectiveness analysis Pamidronate in prevention of bone complications in metastatic breast cancer: a cost-effectiveness analysis Hillner B E, Weeks J C, Desch C E, Smith T J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The technology studied was pamidronate (a bisphosphonate or anti-bone dissolution agent) provided monthly at a dose of 90 mg to women with metastatic breast cancer for the prevention of bone complications. Type of intervention Secondary prevention. Economic study type Cost-utility analysis. Study population The study

NHS Economic Evaluation Database.2000

8640. [Cost effectiveness of cervical cancer screening strategies in Tunisia]

[Cost effectiveness of cervical cancer screening strategies in Tunisia] Cout efficacite des strategies de depistage du cancer du col uterin en Tunisie [Cost effectiveness of cervical cancer screening strategies in Tunisia] Cout efficacite des strategies de depistage du cancer du col uterin en Tunisie [Cost effectiveness of cervical cancer screening strategies in Tunisia] Hsairi M, Fakhfakh R, Ghyoula M, Ben Abdallah M, Achour N Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Cervical cancer screening strategies using the Pap test were compared according to age group and test frequency. Type of intervention Secondary prevention; Screening. Economic study type Cost-effectiveness analysis. Study population The study population

NHS Economic Evaluation Database.2000