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Calcium pyrophosphate deposition Calcium pyrophosphate deposition - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Calcium pyrophosphate deposition Last reviewed: August 2018 Last updated: March 2018 Summary Calcium pyrophosphate arthritis is caused by deposition of calcium pyrophosphate (CPP) crystals. It can be difficult to diagnose as CPP crystals in synovial fluids can be small, sparse, and difficult to find (...) . In patients <60 years of age, underlying metabolic conditions associated with calcium pyrophosphate deposition (CPPD), such as hyperparathyroidism or haemochromatosis, should be investigated. There is no definitive treatment for CPP arthritis but intra-articular corticosteroids can be effective for both acute and chronic forms. Definition Calcium pyrophosphate deposition (CPPD) is associated with both acute and chronic arthritis. Acute CPP crystal arthritis is an acute inflammatory arthritis of one
Early marginal bone stability of dental implants placed in a transalveolarly augmented maxillary sinus: a controlled retrospective study of surface modification with calcium ions RESEARCH Open Access Early marginal bone stability of dental implants placed in a transalveolarly augmented maxillary sinus: a controlled retrospective study of surface modification with calcium ions Eduardo Anitua 1,2,3,5* , Laura Piñas 4 and Mohammad Hamdan Alkhraisat 2,3 Abstract Background: Recently, components (...) of the extracellular cellular matrix have been assessed to enhance the biological response to dental implants. This study aims to assess the effect of surface modification with calcium ions on the early marginal bone loss of dental implants placed in a transalveolarly augmented maxillary sinus. Methods: A retrospective study of transalveolar sinus floor augmentation was conducted in a single private dental clinic. The predictor variable was the surface of the dental implant. The primary outcome was the marginal
Calcium Tartrate Tetrahydrate, Case Report of a Novel Human Kidney Stone Login to your account Username Password Keep me logged in Change Password Old Password New Password Too Short Weak Medium Strong Very Strong Too Long Congrats! Your password has been
Tobacco plants expressing the maize nitrate transporter ZmNrt2.1 exhibit altered responses of growth and gene expression to nitrate and calcium Ibrahim et al. Bot Stud (2017) 58:51 DOI 10.1186/s40529-017-0203-9 ORIGINAL ARTICLE Tobacco plants expressing the maize nitrate transporter ZmNrt2.1 exhibit altered responses of growth and gene expression to nitrate and calcium Abubakar Ibrahim 1,2 , Xiao-Lu Jin 1 , Yu-Bin Zhang 1,3 , Jessica Cruz 1 , Paveena Vichyavichien 1 , Nwadiuto Esiobu 1 and Xing (...) transporter ZmNrt2.1 gene that would bypass the tight control for the endogenous nitrate- responsive genes. By using calcium inhibitors and varying levels of NO 3 - , Ca 2+ and K + , we probed how the host plants were affected in their nitrate response. Results: We found that the ZmNrt2.1- expressing plants had better root growth than the wild type plants when Ca 2+ was deficient regardless of the nitrate levels. The growth restriction associated with Ca 2+ - deficiency can be alleviated with a high level
Collagen and Calcium Binding EGF Domains 1 (CCBE1) in cancer â€“ a new role past lymphatics? 168 www.impactjournals.com/oncoscience Oncoscience www.impactjournals.com/oncoscience/ Oncoscience, Vol. 4(11-12), November 2017 Collagen and Calcium Binding EGF Domains 1 (CCBE1) in cancer – a new role past lymphatics? Aruz Mesci and Stanley K. Liu Genes that influence cancer behavior continue to be the focus of a plethora of research studies, with the hopes of either identifying biomarkers that help (...) predict/ prognosticate disease course, or discovering druggable targets for future therapies. Many of the gene products implicated in cancer also regulate normal developmental processes, hinting at the intimacy of the two processes. Collagen and Calcium Binding EGF Domains 1 (CCBE1) encodes a soluble protein with EGF-like domain and is located in human chromosomal region 18q21.32. Despite its original description as a gene frequently lost in breast cancer specimens , the earliest studies
Comparison of the Coronary Artery Calcium Score and Number of Calcified Coronary Plaques for Predicting Patient Mortality Risk 29096884 2017 11 03 2017 11 03 1879-1913 2017 Sep 18 The American journal of cardiology Am. J. Cardiol. Comparison of the Coronary Artery Calcium Score and Number of Calcified Coronary Plaques for Predicting Patient Mortality Risk. S0002-9149(17)31452-2 10.1016/j.amjcard.2017.09.001 Multiple coronary artery calcium (CAC) parameters have recently been proposed to improve
Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13 29296853 2018 11 13 2473-9529 1 23 2017 Oct 24 Blood advances Blood Adv Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13. 2063-2074 10.1182/bloodadvances.2017009027 von Willebrand factor (VWF) and the metalloprotease a disintegrin and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13) are present (...) both within endothelial cells (ECs) and in peripheral blood. Calcium concentrations are lower in intracellular compartments (80-400 μM) compared with the extracellular milieu (∼1.25 mM). Because low calcium favors VWF A2-domain proteolysis by ADAMTS13, the dependence of proteolysis rates on calcium was assayed both within ECs and in blood. Confocal microscopy studies demonstrate partial perinuclear colocalization of VWF with ADAMTS13 in human umbilical vein ECs (HUVECs). Consequently, low levels (5
Prophylactic intravenous calcium therapy for exchange blood transfusion in the newborn. BACKGROUND: Exchange blood transfusion (EBT) is a form of whole blood transfusion in which the total blood volume is replaced within a few hours. In perinatal and neonatal medicine, EBT is most often used in the management of severe anaemia or severe hyperbilirubinaemia in the first week of life. Hypocalcaemia, one of the common morbidities associated with EBT, is thought to arise from the chelating effects (...) of the citrate commonly used as an anticoagulant in the donor's blood. This disorder manifests with muscular and nervous irritability and cardiac arrhythmias. OBJECTIVES: To determine whether the use of prophylactic calcium reduces the risk of hypocalcaemia-related morbidities and death among newborn infants receiving EBT. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review group to search the Cochrane Central Register of Controlled Trials (CENTRAL 2016, Issue 5), MEDLINE via
Adenosine versus intravenous calcium channel antagonists for supraventricular tachycardia. BACKGROUND: People with supraventricular tachycardia (SVT) frequently are symptomatic and present to the emergency department for treatment. Although vagal manoeuvres may terminate SVT, they often fail, and subsequently adenosine or calcium channel antagonists (CCAs) are administered. Both are known to be effective, but both have a significant side effect profile. This is an update of a Cochrane review (...) in the CCA group and none in the adenosine group (0.66% vs 0%; OR 3.09, 95% CI 0.12 to 76.71; participants = 306; studies = 3; I 2 = 0%). Included trials did not report length of stay in hospital nor patient satisfaction. AUTHORS' CONCLUSIONS: Moderate-quality evidence shows no differences in effects of adenosine and calcium channel antagonists for treatment of SVT on reverting to sinus rhythm, and low-quality evidence suggests no appreciable differences in the incidence of hypotension. A study
Efficacy and Safety of Sucroferric Oxyhydroxide and Calcium Carbonate in Hemodialysis Patients 29340330 2018 11 13 2468-0249 3 1 2018 Jan Kidney international reports Kidney Int Rep Efficacy and Safety of Sucroferric Oxyhydroxide and Calcium Carbonate in Hemodialysis Patients. 185-192 10.1016/j.ekir.2017.10.003 In this phase III, open-label, single-arm, multi-center 12-week study, we evaluated the efficacy and safety of combination therapy with sucroferric oxyhydroxide (PA21) and calcium (...) carbonate for hemodialysis patients with hyperphosphatemia. We enrolled 35 subjects aged ≥ 20 years with end-stage kidney disease and serum phosphorus 3.5-6.0 mg/dl who were undergoing hemodialysis 3 times weekly and taking calcium carbonate and sevelamer hydrochloride. Patients switched from sevelamer hydrochloride and calcium carbonate to sucroferric oxyhydroxide and calcium carbonate. Sucroferric oxyhydroxide was orally administered 3 times daily within 750 mg/d (250 mg per dose) to 3000 mg/d (1000
Calcium supplementation commencing before or early in pregnancy, or food fortification with calcium, for preventing hypertensive disorders of pregnancy. BACKGROUND: Pre-eclampsia is considerably more prevalent in low- than high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half of pregnancy reduces the serious consequences of pre-eclampsia and is recommended by the World Health (...) Organization (WHO) for women with low dietary calcium intake, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before and in early pregnancy has added benefit. Such evidence would be justification for population-level fortification of staple foods with calcium. OBJECTIVES: To determine the effect of calcium supplementation or food fortification with calcium, commenced before or early in pregnancy and continued at least until mid
Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies 28746709 2018 11 13 2380-6591 2 9 2017 Sep 01 JAMA cardiology JAMA Cardiol Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies. 986-994 10.1001/jamacardio.2017.2498 Besides age, other discriminators of atherosclerotic cardiovascular disease (ASCVD) risk are needed (...) in older adults. To examine the predictive ability of coronary artery calcium (CAC) score vs age for incident ASCVD and how risk prediction changes by adding CAC score and removing only age from prediction models. We conducted an analysis of pooled US population-based studies, including the Framingham Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study. Results were compared with 2 European cohorts, the Rotterdam Study and the Heinz Nixdorf Recall Study
Magnesium disorders can cause calcium pyrophosphate deposition disease: A case report and literature review 29657876 2018 11 30 2147-9720 5 1 2018 Mar European journal of rheumatology Eur J Rheumatol Magnesium disorders can cause calcium pyrophosphate deposition disease: A case report and literature review. 53-57 10.5152/eurjrheum.2017.16116 Calcium pyrophosphate deposition (CPPD) disease, also known as pseudogout, is one of the most common forms of inflammatory arthritis. A variety (...) are summarized in this paper. Joshi Akanksha A http://orcid.org/0000-0002-2230-3761 Division of Rheumatology, Department of Internal Medicine, University of Missouri, Columbia, MO, USA. Siva Chokkalingam C http://orcid.org/0000-0002-4546-762X Division of Rheumatology, Department of Internal Medicine, University of Missouri, Columbia, MO, USA. eng Journal Article Review 2017 08 29 Turkey Eur J Rheumatol 101656068 2147-9720 CPPD Magnesium calcium pyrophosphate deposition disease chondrocalcinosis
Hypocalciuria as a Predictor of Reduced Intestinal Calcium Absorption 29264573 2018 11 13 2472-1972 1 9 2017 Sep 01 Journal of the Endocrine Society J Endocr Soc Hypocalciuria as a Predictor of Reduced Intestinal Calcium Absorption. 1179-1187 10.1210/js.2017-00234 Impaired intestinal calcium absorption contributes to osteoporosis, but its measurement is limited to research settings. We hypothesized that 24-hour urine calcium (24HUC) values could diagnose low fractional calcium absorption (FCA (...) ). We performed a post hoc analysis of clinical trial data to determine whether 24HUC predicted low FCA compared with the gold standard dual calcium isotope method. Two hundred thirty postmenopausal women <75 years old without osteoporosis underwent 445 FCA measurements using calcium isotopes (8 mg of oral 44 Ca, 3 mg of intravenous 42 Ca) and a 24-hour inpatient urine collection at 0 and 12 months. We determined subjects' total calcium intake via review of food diaries and supplements. Net calcium
The use of a biphasic calcium phosphate in a maxillary sinus floor elevation procedure: a clinical, radiological, histological, and histomorphometric evaluation with 9- and 12-month healing times 28741276 2018 11 13 2198-4034 3 1 2017 Dec International journal of implant dentistry Int J Implant Dent The use of a biphasic calcium phosphate in a maxillary sinus floor elevation procedure: a clinical, radiological, histological, and histomorphometric evaluation with 9- and 12-month healing times (...) . 34 10.1186/s40729-017-0099-x This study evaluates the clinical, radiological, histological, and histomorphometric aspects of a fully synthetic biphasic calcium phosphate (BCP) (60% hydroxyapatite and 40% ß-tricalcium phosphate), used in a human maxillary sinus floor elevation (MSFE) procedure with 9- and 12-month healing time. A unilateral MSFE procedure, using 100% BCP, was performed in two series of five patients with healing times of 9 and 12 months respectively. Clinical and radiological
Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction. Importance: Serum calcium has been associated with cardiovascular disease in observational studies and evidence from randomized clinical trials indicates that calcium supplementation, which raises serum calcium levels, may increase the risk of cardiovascular events, particularly myocardial infarction. Objective: To evaluate the potential causal association between genetic (...) variants related to elevated serum calcium levels and risk of coronary artery disease (CAD) and myocardial infarction using mendelian randomization. Design, Setting, and Participants: The analyses were performed using summary statistics obtained for single-nucleotide polymorphisms (SNPs) identified from a genome-wide association meta-analysis of serum calcium levels (N = up to 61 079 individuals) and from the Coronary Artery Disease Genome-wide Replication and Meta-analysis Plus the Coronary