Latest & greatest articles for calcium

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Top results for calcium

181. Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance

Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance Fenton TR, Lyon AW, Eliasziw M, Tough SC, Hanley DA CRD summary This review evaluated the effects of diet manipulation on urine calcium, calcium balance and bone health in healthy adults. The authors concluded that increasing (...) diet acid load did not promote skeletal bone mineral loss or osteoporosis. The review had several potential methodological limitations, including unclear quality of included studies, and so the reliability of the authors' conclusion is uncertain. Authors' objectives To evaluate the effects of diet manipulation on urine calcium, calcium balance and bone health in healthy adults. Searching MEDLINE, EMBASE, CINAHL, Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled

DARE.2009

182. Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers

Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers Makarounas-Kirchmann K, Glover-Koudounas S, Ferrari P CRD summary This review concluded that lercanidipine was associated (...) with a lower risk of peripheral oedema and treatment withdrawal due to peripheral edema when compared with first-generation dihydropyridine calcium channel blockers, but not when compared with second-generation drugs. A degree of caution might be required in interpreting the authors' conclusions given the limited quality of included studies. Authors' objectives To compare the efficacy and safety of lercanidipine with other dihydropyridine calcium channel blockers in the treatment of hypertension. Searching

DARE.2009

183. Racial differences in blood pressure response to calcium channel blocker monotherapy: a meta-analysis

Racial differences in blood pressure response to calcium channel blocker monotherapy: a meta-analysis Racial differences in blood pressure response to calcium channel blocker monotherapy: a meta-analysis Racial differences in blood pressure response to calcium channel blocker monotherapy: a meta-analysis Nguyen TT, Kaufman JS, Whitsel EA, Cooper RS CRD summary The review concluded that blood pressure response to calcium channel blocker monotherapy was qualitatively similar in blacks and whites (...) in USA. The authors' conclusions appeared to broadly reflect the evidence presented, but the restriction of using only trial data and limitations in the review processes made their reliability uncertain. Authors' objectives To determine whether United States blacks and whites have differential blood pressure response to calcium channel blocker monotherapy. Searching PubMed, EMBASE and Cochrane Central Register of Clinical Trials (CENTRAL) were searched for published studies between 1990 and October

DARE.2009

185. Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance?

Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance? Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance? Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance? Shaukat A, Parekh M, Lipscomb J, Ladabaum U Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion (...) on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of calcium instead of or in addition to surveillance, in 50-year-old patients immediately after polypectomy, for the prevention of adenoma recurrence and colorectal cancer. The authors concluded that calcium after polypectomy was unlikely

NHS Economic Evaluation Database.2009

186. Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175,634 patients

Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175,634 patients Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175,634 patients Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175,634 patients Costanzo P, Perrone-Filardi P, Petretta M, Marciano C, Vassallo E, Gargiulo P, Paolillo S, Petretta A, Chiariello M CRD summary This review concluded that calcium channel blockers (CCBs) reduced risk of stroke and heart (...) failure (compared to placebo) and dihydropyridine CCBs reduced risk of all-cause mortality (compared with active therapy) in high-risk cardiac patients. The reliability of these findings is unclear due to potential limitations in the data and methodology and the author's own reservations. Authors' objectives To evaluate the safety and effectiveness of calcium channel blockers compared to other drugs or placebo in reducing cardiovascular outcomes. Searching MEDLINE, The Cochrane Library and DARE, were searched

DARE.2009

187. Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis

Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis Bangalore S, Parkar S, Messerli FH CRD summary The authors found that long-acting calcium channel blockers were associated with a reduced risk of stroke, angina pectoris and heart failure, and with a similar risk of other (...) cardiovascular events, when compared to other antihypertensives or placebo. The review was generally well conducted, but a degree of caution may be advisable in interpreting the findings, due to some unexplained heterogeneity. Authors' objectives To evaluate the use of long-acting calcium channel blockers (CCBs) in patients with known coronary artery disease. Searching MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL) and EMBASE were searched from 1966 to August 2008. Search terms were

DARE.2009

188. The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis

The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis Jamal SA, Fitchett D, Lok CE, Mendelssohn DC, Tsuyuki RT CRD (...) summary The review assessed the effects of calcium-based versus non-calcium-based phosphate binders on mortality, cardiovascular events and vascular calcification in patients with chronic kidney disease. Although no significant differences were found, the results did not exclude an important beneficial effect of non-calcium-based phosphate binders. The authors' conclusions are appropriately conservative given the quality of the included studies. Authors' objectives To assess the effects of calcium

DARE.2009

189. Calcium and bone health: position statement for the Australian and New Zealand Bone and Mineral Society, Osteoporosis Australia and the Endocrine Society of Australia

Calcium and bone health: position statement for the Australian and New Zealand Bone and Mineral Society, Osteoporosis Australia and the Endocrine Society of Australia Calcium and bone health: position statement for the Australian and New Zealand Bone and Mineral Society, Osteoporosis Australia and the Endocrine Society of Australia | Medical Journal of Australia Search form Search Articles Topics MJA team Author centre Multimedia Centenary Place an ad secondlevel Position statement Calcium (...) of Australia. Currently, the balance of evidence remains in favour of fracture prevention from combined calcium and vitamin D supplementation in elderly men and women. Adequate vitamin D status is essential for active calcium absorption in the gut and for bone development and remodelling. In adults with a baseline calcium intake of 500–900 mg/day, increasing or supplementing this intake by a further 500–1000 mg/day has a beneficial effect on bone mineral density. Calcium intake significantly above

MJA Clinical Guidelines2009

190. Class Act: Cardiac CT to Assess Coronary Artery Calcium

Class Act: Cardiac CT to Assess Coronary Artery Calcium Class Act: Cardiac CT to Assess Coronary Artery Calcium | Clinical Correlations Class Act: Cardiac CT to Assess Coronary Artery Calcium May 17, 2009 Matthew Nayor Faculty Peer Reviewed The patient: a 55 year old male nonsmoker with an HDL of 46, LDL of 120, triglycerides of 70, BP of 135/80 (on meds) and total cholesterol of 180. (Framingham 10-year risk of MI = 12%) Coronary artery disease is the leading cause of death worldwide. Despite (...) -risk patients are at greater risk and might benefit from more aggressive preventive measures. One such possibility is the use of cardiac CT to assess coronary artery calcium (CAC). Coronary artery calcifications are absent in normal vessels, but are highly correlated with coronary artery disease (CAD). They are therefore pathognomonic for atherosclerosis and can now be reliably detected by CT scanning. When these scans are evaluated, the patient is assigned a score that represents the coronary

Clinical Correlations2009

191. Effect of calcium dobesilate on occurrence of diabetic macular oedema (CALDIRET study): randomised, double-blind, placebo-controlled, multicentre trial.

Effect of calcium dobesilate on occurrence of diabetic macular oedema (CALDIRET study): randomised, double-blind, placebo-controlled, multicentre trial. 19376452 2009 04 20 2009 05 01 2015 06 16 1474-547X 373 9672 2009 Apr 18 Lancet (London, England) Lancet Effect of calcium dobesilate on occurrence of diabetic macular oedema (CALDIRET study): randomised, double-blind, placebo-controlled, multicentre trial. 1364-71 10.1016/S0140-6736(09)60218-X Medical treatment for diabetic retinopathy could (...) have an important role in prevention of complications such as visual loss. We aimed to assess the effect of calcium dobesilate on occurrence of diabetic macular oedema. We undertook a randomised, double-blind, placebo-controlled, multicentre study in 40 centres in 11 countries. We enrolled outpatients with adult-onset type 2 diabetes and mild-to-moderate non-proliferative diabetic retinopathy, and randomly allocated them via sealed envelopes either calcium dobesilate (1500 mg per day) or placebo

Lancet2009

192. Randomized controlled trial of calcium supplementation in healthy, nonosteoporotic, older men

Randomized controlled trial of calcium supplementation in healthy, nonosteoporotic, older men 19001206 2008 11 12 2008 12 01 2013 11 21 1538-3679 168 20 2008 Nov 10 Archives of internal medicine Arch. Intern. Med. Randomized controlled trial of calcium supplementation in healthy, nonosteoporotic, older men. 2276-82 10.1001/archinte.168.20.2276 There is no consistent evidence, to our knowledge, that calcium supplementation affects bone mineral density (BMD) in men, despite male osteoporosis (...) being a common clinical problem. To determine the effects of calcium supplementation (600 mg/d, 1200 mg/d, or placebo) on BMD in men, we conducted a double-blind, randomized controlled trial for a 2-year period at an academic clinical research center. A total of 323 healthy men at least 40 years old (mean age, 57 years) were recruited by newspaper advertisement. Complete follow-up was achieved in 96% of subjects. The BMD increased at all sites in the group receiving calcium, 1200 mg/d, by 1% to 1.5

EvidenceUpdates2008

193. Calcium antagonists for Duchenne muscular dystrophy.

Calcium antagonists for Duchenne muscular dystrophy. BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive muscle condition starting in childhood, leading to severe disability and a shortened life span. It is due to severe deficiency of the protein dystrophin which performs both structural and signalling roles within skeletal and cardiac myocytes. Calcium accumulates in dystrophic muscle cells and plays a role in cell damage. It has been hypothesised that use of calcium (...) antagonists might reduce this calcium load and its toxic effect on muscle cells. OBJECTIVES: To evaluate the effects of calcium antagonists on muscle function and muscle strength in people with DMD. SEARCH STRATEGY: The Cochrane Neuromuscular Disease Group Trials Register (February 2008), MEDLINE (from January 1950 to March 2008) and EMBASE (from January 1947 to March 2008) were searched. Search terms were 'calcium antagonists' or 'calcium channel blocker' or 'dantrolene' or 'verapamil' or 'nifedipine

Cochrane2008

194. Parenteral calcium for intensive care unit patients.

Parenteral calcium for intensive care unit patients. BACKGROUND: Hypocalcemia is prevalent among critically ill patients requiring intensive care. Several epidemiological studies highlight a direct association between hypocalcemia and mortality. These data provide the impetus for current guidelines recommending parenteral calcium administration to normalize serum calcium. However, in light of the considerable variation in the threshold for calcium replacement, the lack of evidence to support (...) a causal role of hypocalcemia in mortality, and animal studies illustrating that calcium supplementation may worsen outcomes, a systematic review is essential to evaluate whether or not the practice of calcium supplementation for intensive care unit (ICU) patients provides any benefit. OBJECTIVES: To assess the effects of parenteral calcium administration in ICU patients on the following outcomes: mortality, multiple organ dysfunction, ICU and hospital length of stay, costs, serum ionized calcium

Cochrane2008

195. Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study

Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study 18573867 2008 09 15 2008 11 13 2016 12 03 1522-9645 29 18 2008 Sep European heart journal Eur. Heart J. Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study. 2244-51 10.1093/eurheartj/ehn279 The PREDICT Study is a prospective cohort study designed to evaluate coronary

EvidenceUpdates2008

196. Combining dual-source computed tomography coronary angiography and calcium scoring: added value for the assessment of coronary artery disease

Combining dual-source computed tomography coronary angiography and calcium scoring: added value for the assessment of coronary artery disease 18032458 2008 08 15 2008 09 05 2009 04 16 1468-201X 94 9 2008 Sep Heart (British Cardiac Society) Heart Combining dual-source computed tomography coronary angiography and calcium scoring: added value for the assessment of coronary artery disease. 1154-61 To prospectively investigate the diagnostic accuracy of dual-source 64-slice computed tomography (...) coronary angiography (CTCA), calcium scoring (CS) and both methods combined for assessing significant coronary artery stenoses relative to conventional coronary angiography (CCA). Prospective, single-centre study conducted in a referral centre enrolling 74 consecutive patients (24 women; mean age 62 (SD 12) years) from August-October 2006. All study participants underwent CS, CTCA and CCA. Diagnostic accuracy was calculated for CS, CTCA and both methods combined relative to CCA. Not-evaluative segments

EvidenceUpdates2008

197. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient

Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2008

198. Prehypertension during young adulthood and coronary calcium later in life.

Prehypertension during young adulthood and coronary calcium later in life. BACKGROUND: High blood pressure in middle age is a well-established risk factor for cardiovascular disease, but the consequences of low-level elevations during young adulthood are unknown. OBJECTIVE: To measure the association between prehypertension exposure before age 35 years and coronary calcium later in life. DESIGN: Prospective cohort study. SETTING: Four communities in the United States. PARTICIPANTS: Black (...) ) from age 20 to 35 years was calculated in units of mm Hg-years (similar to pack-years of tobacco exposure) and related to the presence of coronary calcium measured at each participant's last examination (mean age, 44 years [SD, 4]). RESULTS: Among 3560 participants, the 635 (18%) who developed prehypertension before age 35 years were more often black, male, overweight, and of lower socioeconomic status. Exposure to prehypertension before age 35 years, especially systolic prehypertension, showed

Annals of Internal Medicine2008 Full Text: Link to full Text with Trip Pro

199. Coronary artery calcium to predict all-cause mortality in elderly men and women

Coronary artery calcium to predict all-cause mortality in elderly men and women 18582630 2008 06 27 2008 07 22 2008 06 27 1558-3597 52 1 2008 Jul 01 Journal of the American College of Cardiology J. Am. Coll. Cardiol. Coronary artery calcium to predict all-cause mortality in elderly men and women. 17-23 10.1016/j.jacc.2008.04.004 We sought to study the prognostic utility of coronary artery calcium (CAC) in the elderly. The prognostic significance of CAC in the elderly is not well known. All

EvidenceUpdates2008

200. Calcium use during in-hospital pediatric cardiopulmonary resuscitation: a report from the National Registry of Cardiopulmonary Resuscitation

Calcium use during in-hospital pediatric cardiopulmonary resuscitation: a report from the National Registry of Cardiopulmonary Resuscitation 18450859 2008 05 02 2008 06 04 2013 11 21 1098-4275 121 5 2008 May Pediatrics Pediatrics Calcium use during in-hospital pediatric cardiopulmonary resuscitation: a report from the National Registry of Cardiopulmonary Resuscitation. e1144-51 10.1542/peds.2007-1555 Specific patterns of calcium use during in-hospital pediatric cardiopulmonary resuscitation (...) have not been reported since publication of pediatric advanced life support guidelines by the American Heart Association in 2000 recommended that calcium use during cardiopulmonary resuscitation be limited to select circumstances. We hypothesized that calcium is used frequently during in-hospital pediatric cardiopulmonary resuscitation and that its use is associated with worse survival to hospital discharge. We reviewed 1477 consecutive pediatric cardiopulmonary resuscitation index events

EvidenceUpdates2008