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Latest & greatest articles for bronchiolitis
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Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.
Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.
In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.
Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.
Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.
Read more on medications used to treat bronchiolitis and the causes of the virus.
Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Garrison M M, Christakis D A, Harvey E, Cummings P, Davis R L Authors' objectives To determine whether corticosteroids are efficacious in treating bronchiolitis in hospitalised infants. Searching The following sources were searched: MEDLINE from 1966 to January 1999, the Cochrane Controlled Trials (...) Register (as of January 1999), and EMBASE from January 1990 to January 1999. The search terms included 'bronchiolitis', 'respiratory syncytial viruses', 'adrenal cortex hormones', 'corticosteroid', 'glucocorticoid', 'antiinflammatory agents' and 'steroidal'. The bibliographies of review articles and all selected articles were examined. No language restrictions were reported. Study selection Study designs of evaluations included in the review Randomised placebo-controlled studies. The studies had
Sustaining the implementation of an evidence-based guideline for bronchiolitis Sustaining the implementation of an evidence-based guideline for bronchiolitis Sustaining the implementation of an evidence-based guideline for bronchiolitis Perlstein P H, Kotagal U R, Schoettker P J, Atherton H D, Farrell M K, Gerhardt W E, Alfaro M P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of evidence-based guidelines in the treatment of children with bronchiolitis for a period of more than one year. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study considered infants 1 year old or younger, who were admitted to the hospital with a first-time episode of typical
Bronchodilators for bronchiolitis. OBJECTIVES: Bronchiolitis is an acute, highly communicable lower respiratory tract infection. Bronchodilators are commonly used in the management of bronchiolitis in North America, but not in the United Kingdom. The objective of this review was to assess the effects of bronchodilators for bronchiolitis. SEARCH STRATEGY: We searched MEDLINE, EMBASE, Reference Update, reference lists of articles, and the files of two of the authors up to June 1998. SELECTION (...) CRITERIA: Randomised trials comparing bronchodilators with placebo in the treatment of bronchiolitis. DATA COLLECTION AND ANALYSIS: Two reviewers independently assessed trial quality and extracted data. Unpublished data were requested from authors when necessary. MAIN RESULTS: In eight trials with 394 children, 46% demonstrated an improved clinical score with bronchodilators compared to 75% with placebo (odds ratio for no improvement 0.29, 95% confidence interval 0.19 to 0.45). However, the inclusion
Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Flores G, Horwitz R I Authors' objectives To evaluate the efficacy of beta2-agonists as bronchodilator therapy in bronchiolitis. Searching MEDLINE was searched up to January 1995 using 'bronchiolitis' and 'drug therapy' both as MeSH terms and as textwords. Additional (...) was not restricted by language. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) of inhaled beta2-agonists were included in the review. Studies which used outcomes evaluable only in a pulmonary laboratory were excluded. Specific interventions included in the review Bronchodilator therapy for bronchiolitis, specifically inhaled beta2-agonists (fenoterol and albuterol of varying dosages and number of doses). No specific comparator was required in the inclusion
Randomized double blind placebo controlled trial of prednisolone in children admitted to hospital with respiratory syncytial virus bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: A randomized, controlled trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Kellner J D, Ohlsson A, Gadomski A M, Wang E E Authors' objectives To determine if bronchodilators are efficacious in treating bronchiolitis in infants. Searching MEDLINE was searched from January 1966 to September 1994, Excerpta Medica from January 1974 to November 1995), and Reference (...) Update on selected dates (November 8, 1993; June 29, 1994; and April 26, 1995), using the search terms (explode)'bronchiolitis' combined with 'albuterol', 'ipratropium', 'adrenergic agents' or 'bronchodilator agents'. Addition material was obtained by examining the authors' files and the bibliographies of all retrieved articles. Study selection Study designs of evaluations included in the review Randomised placebo-controlled trials were included. Specific interventions included in the review
Dexamethasone in bronchiolitis: a randomised controlled trial. 8709687 1996 09 06 1996 09 06 2015 06 16 0140-6736 348 9023 1996 Aug 03 Lancet (London, England) Lancet Dexamethasone in bronchiolitis: a randomised controlled trial. 292-5 Although corticosteroids are commonly prescribed in the treatment of bronchiolitis, there is no evidence on the efficacy of these drugs in this disorder. We designed a randomised, double-blind, prospective study to assess the efficacy of dexamethasone in infants (...) with bronchiolitis who require hospital management. Infants younger than 12 months who had been admitted to hospital for an initial episode of wheezing, were randomly allocated intramuscular dexamethasone (1 mg/kg daily) or placebo, every 24 h for three doses. We excluded infants who were younger than 4 weeks, who required admission to the intensive care unit, or who had a history of congenital heart disease, mechanical ventilation, or supplemental oxygen use. We assessed infants on admission and every 12 h