Latest & greatest articles for bronchiolitis

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Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

121. Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia (Full text)

Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Article Text Therapeutics

2015 Evidence-Based Medicine PubMed abstract

122. Are Antibiotics Effective in the Treatment of Acute Bronchitis?

Are Antibiotics Effective in the Treatment of Acute Bronchitis? Systematic Review Snapshot TAKE-HOME MESSAGE In patients without underlying lung disease, antibiotics in acute bronchitis appear to decrease cough, but the clinical signi?cance of this decrease is uncertain. Their use should be weighed against the cost and potential adverse effects for treatment of a self-limiting disease. Are Antibiotics Effective in the Treatment of Acute Bronchitis? EBEM Commentators Manpreet Singh, MD (...) versus control (placebo/no treatment) in acute bronchitis. Clinically Improved Cough Night Cough Shorter Mean Cough Duration Reduction in Ill Feeling Days Reduction in Limited Activity Days Adverse Side Effects RR 1.07 RR 0.64 RR 0.67 MD -0.46 days MD -0.64 days MD -0.49 days RR 1.20 0.99 to 1.15* 0.49 to 0.85* 0.54 to 0.83* -0.87 to -0.04* -0.94 to -0.04* -0.94 to -0.04 CI 1.05 to 1.36* NNT 22 NNT 6 NNT 7 NNH 5 NNT, Number needed to treat; MD, mean difference; NNH, number needed to harm. *95% CI

2015 Annals of Emergency Medicine Systematic Review Snapshots

123. Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis

Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Article Text Therapeutics/Prevention Randomised controlled trial Nebulised hypertonic

2015 Evidence-Based Medicine

124. Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer. (Full text)

Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer. Radiation therapy for breast cancer has been implicated in the development of bronchiolitis obliterans organizing pneumonia (BOOP). This inflammatory lung disorder was first noted in 1983, and there have been numerous reports of BOOP occurring in women who have had radiation therapy for breast cancer since 1995. This study was undertaken to perform a systematic review

2014 The oncologist PubMed abstract

125. Effects of prednisone on eosinophilic bronchitis in asthma: a systematic review and meta-analysis. (Full text)

Effects of prednisone on eosinophilic bronchitis in asthma: a systematic review and meta-analysis. To evaluate the effect size of oral corticosteroid treatment on eosinophilic bronchitis in asthma, through systematic review and meta-analysis.We systematically reviewed articles in the Medline, Cochrane Controlled Trials Register, EMBASE, and LILACS databases. We selected studies meeting the following criteria: comparing at least two groups or time points (prednisone vs. control, prednisone vs (...) -bronchodilator FEV1.The pooled analysis of the pre- vs. post-treatment data revealed a significant mean reduction in sputum eosinophils (↓8.18%; 95% CI: 7.69-8.67; p < 0.001), sputum IL-5 (↓83.64 pg/mL; 95% CI: 52.45-114.83; p < 0.001), and sputum ECP (↓267.60 µg/L; 95% CI: 244.57-290.63; p < 0.0001), as well as a significant mean increase in post-bronchodilator FEV1 (↑8.09%; 95% CI: 5.35-10.83; p < 0.001).In patients with moderate-to-severe eosinophilic bronchitis, treatment with prednisone caused

2014 Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia PubMed abstract

126. Hyponatremia in Children with Bronchiolitis Admitted to the Pediatric Intensive Care Unit Is Associated with Worse Outcomes

Hyponatremia in Children with Bronchiolitis Admitted to the Pediatric Intensive Care Unit Is Associated with Worse Outcomes PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

127. Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age

Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age Bronchiolitis is the most common reason for admission to hospital in the first year of life. There is tremendous variation in the clinical management of this condition across Canada and around the world, including significant use of unnecessary tests and ineffective therapies. This statement pertains to generally healthy children ≤24 months of age with bronchiolitis. The diagnosis (...) of bronchiolitis is based primarily on the history of illness and physical examination findings. Laboratory investigations are generally unhelpful. Bronchiolitis is a self-limiting disease, usually managed with supportive care at home. Groups at high risk for severe disease are described and guidelines for admission to hospital are presented. Evidence for the efficacy of various therapies is discussed and recommendations are made for management. Monitoring requirements and discharge readiness from hospital

2014 Canadian Paediatric Society

128. Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts. (Full text)

Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts. This study aimed to assess associations of outdoor air pollution on prevalence of chronic bronchitis symptoms in adults in five cohort studies (Asthma-E3N, ECRHS, NSHD, SALIA, SAPALDIA) participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE) project.Annual average particulate matter (PM(10), PM(2.5), PM(absorbance), PM(coarse)), NO(2), nitrogen oxides (...) (NO(x)) and road traffic measures modelled from ESCAPE measurement campaigns 2008-2011 were assigned to home address at most recent assessments (1998-2011). Symptoms examined were chronic bronchitis (cough and phlegm for ≥3 months of the year for ≥2 years), chronic cough (with/without phlegm) and chronic phlegm (with/without cough). Cohort-specific cross-sectional multivariable logistic regression analyses were conducted using common confounder sets (age, sex, smoking, interview season, education

2014 Thorax PubMed abstract

129. Do glucocorticoids provide benefit to children with bronchiolitis? (Abstract)

Do glucocorticoids provide benefit to children with bronchiolitis? 24582604 2015 01 29 2014 09 27 1097-6760 64 4 2014 Oct Annals of emergency medicine Ann Emerg Med Do glucocorticoids provide benefit to children with bronchiolitis? 389-91 10.1016/j.annemergmed.2014.01.026 S0196-0644(14)00088-2 Ng Carrie C Department of Emergency Medicine, New York University School of Medicine, Bellevue Hospital Center, New York, NY. Foran Mark M Department of Emergency Medicine, New York University School (...) of Medicine, Bellevue Hospital Center, New York, NY. Koyfman Alex A Department of Emergency Medicine, UT Southwestern Medical School, Parkland Memorial Hospital, Dallas, TX. eng Journal Article Meta-Analysis Review 2014 02 28 United States Ann Emerg Med 8002646 0196-0644 0 Glucocorticoids AIM IM Acute Disease Administration, Inhalation Bronchiolitis drug therapy Child, Preschool Glucocorticoids therapeutic use Hospitalization Humans Infant Length of Stay Treatment Outcome 2014 01 18 2014 01 27 2014 01 27

2014 Annals of Emergency Medicine

130. Effectiveness of quality improvement in hospitalization for bronchiolitis: a systematic review. (Full text)

Effectiveness of quality improvement in hospitalization for bronchiolitis: a systematic review. Bronchiolitis causes nearly 20% of all acute care hospitalizations for young children in the United States. Unnecessary testing and medication for infants with bronchiolitis contribute to cost without improving outcomes.The goal of this study was to systematically review the quality improvement (QI) literature on inpatient bronchiolitis and to propose benchmarks for reducing unnecessary care.Assisted (...) bronchodilator use, 16%; steroid use, 1%; chest radiography use, 42%; and antibiotic use, 17%. The study's heterogeneity limited the ability to classify specific characteristics of effective QI interventions.QI strategies have been demonstrated to achieve lower rates of unnecessary care in children hospitalized with viral bronchiolitis than are the norm.Copyright © 2014 by the American Academy of Pediatrics.

2014 Pediatrics PubMed abstract

131. A systematic review of predictive modeling for bronchiolitis. (Full text)

A systematic review of predictive modeling for bronchiolitis. Bronchiolitis is the most common cause of illness leading to hospitalization in young children. At present, many bronchiolitis management decisions are made subjectively, leading to significant practice variation among hospitals and physicians caring for children with bronchiolitis. To standardize care for bronchiolitis, researchers have proposed various models to predict the disease course to help determine a proper management plan (...) . This paper reviews the existing state of the art of predictive modeling for bronchiolitis. Predictive modeling for respiratory syncytial virus (RSV) infection is covered whenever appropriate, as RSV accounts for about 70% of bronchiolitis cases.A systematic review was conducted through a PubMed search up to April 25, 2014. The literature on predictive modeling for bronchiolitis was retrieved using a comprehensive search query, which was developed through an iterative process. Search results were limited

2014 International journal of medical informatics PubMed abstract

132. Azithromycin improves lung function in patients with post-lung transplant bronchiolitis obliterans syndrome: a meta-analysis. (Abstract)

Azithromycin improves lung function in patients with post-lung transplant bronchiolitis obliterans syndrome: a meta-analysis. Azithromycin has been shown to reverse or halt the decline of forced expiratory volume in one s (FEV1) in patients with bronchiolitis obliterans (BOS) syndrome following lung transplant. The overall effect of azithromycin on the absolute values of FEV1 has not been compared between reported studies. We studied the effects of azithromycin on lung function in patients

2014 Clinical transplantation

133. Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: a systematic review and meta-analysis. (Full text)

Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: a systematic review and meta-analysis. A number of small studies have suggested a relationship between vitamin D status and severe acute lower respiratory tract infection (ALRI), including RSV-bronchiolitis. The objective of this study was to evaluate the relationship between vitamin D receptor (VDR) polymorphism and severe RSV-bronchiolitis through a systemic literature review and meta-analysis.A comprehensive electronic (...) and severe RSV-bronchiolitis was evident at the allele or genotype level.Available literature supports an association between the FokI polymorphism and severe RSV disease. Determination of VDR receptor polymorphism status could help predict high-risk infants who might benefit from preventive measures.© 2013 Wiley Periodicals, Inc.

2014 Pediatric pulmonology PubMed abstract

134. High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial (Full text)

High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis. In addition, it could improve comfort and reduce length of hospital stay (LOS) and admission to Paediatric Intensive Care Unit (PICU).Randomised Clinical Trial from 1 October 2010 to 31 December 2012.Two urban secondary (...) (no PICU available) paediatric hospitalisation units.Hospitalised children aged up to 6 months with moderate acute bronchiolitis (Respiratory Distress Assessment Instrument, RDAI ≥4).Patients were randomised to HHHFNC or HSS. All of them received epinephrine as bronchodilator.Primary outcome was difference in mean Respiratory Assessment Change Score (RACS) between both groups measured in six previously defined consecutive moments. Secondary outcomes were difference in mean comfort scores in this period

2014 EvidenceUpdates Controlled trial quality: predicted high PubMed abstract

135. High-flow nasal cannula therapy for infants with bronchiolitis. (Full text)

High-flow nasal cannula therapy for infants with bronchiolitis. Bronchiolitis is a common lower respiratory tract illness, usually of viral aetiology, affecting infants younger than 24 months of age and is a frequent cause of hospitalisation. It causes airway inflammation, mucus production and mucous plugging, resulting in airway obstruction. Effective pharmacotherapy is lacking and bronchiolitis is a major cause of morbidity and mortality.Conventional treatment consists of supportive therapy (...) in either group required further respiratory support. Five ongoing trials were identified but no data were available in May 2013. We were not able to perform a meta-analysis.There is insufficient evidence to determine the effectiveness of HFNC therapy for treating infants with bronchiolitis. The current evidence in this review is of low quality, from one small study with uncertainty about the estimates of effect and an unclear risk of performance and detection bias. The included study provides some

2014 Cochrane PubMed abstract

136. Bronchiolitis

Bronchiolitis Bronchiolitis - Clinical Practice Guideline -- Clinical Recommendation Welcome Search Search Specify your search AAFP.org Patient Care Clinical Practice Guideline Bronchiolitis Diagnosis and Management of Bronchiolitis (Endorsed, December 2014) The guideline, Diagnosis and Management of Bronchiolitis , was developed by the American Academy of Pediatrics and endorsed by the American Academy of Family Physicians. Key Recommendations The diagnosis of bronchiolitis and assessment (...) of disease severity should be based on history and physical examination. Laboratory and radiologic studies should not be routinely ordered for diagnosis. Risk factors for severe disease such as age < 12 weeks, premature birth, underlying cardiopulmonary disease, or immunodeficiency should be assessed when making decisions about evaluation and management of children with bronchiolitis. Bronchodilators (albuterol, salbutamol), epinephrine, and corticosteroids should not be administered to infants

2014 American Academy of Family Physicians

137. Diagnosis and Management of Bronchiolitis Obliterans Syndrome: An Official ATS/ERS/ISHLT Clinical Practice Guideline

Diagnosis and Management of Bronchiolitis Obliterans Syndrome: An Official ATS/ERS/ISHLT Clinical Practice Guideline An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome Keith C. Meyer 1 , Ganesh Raghu 2 , Geert M. Verleden 3 , Paul A. Corris 4 , Paul Aurora 5 , Kevin C. Wilson 6 , Jan Brozek 7 , Allan R. Glanville 8 and the ISHLT/ATS/ERS BOS Task Force Committee 9 Affiliations: 1 School of Medicine and Public Health (...) and their affiliations can be found in the Acknowledgements section. Correspondence: Keith C. Meyer, University of Wisconsin Lung Transplant and Advanced Pulmonary Disease Program, Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin, Madison, WI, USA. E-mail: kcm@medicine.wisc.edu ABSTRACT Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that is associated with poor survival. The International Society for Heart and Lung

2014 American Thoracic Society

138. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis

Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies (...) with the greatest impact on clinical care. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis Shawn L. Ralston , Allan S. Lieberthal , H. Cody Meissner , Brian K. Alverson , Jill E. Baley , Anne M. Gadomski , David W. Johnson , Michael J. Light , Nizar F. Maraqa , Eneida A. Mendonca , Kieran J. Phelan , Joseph J. Zorc , Danette Stanko-Lopp , Mark A. Brown , Ian Nathanson , Elizabeth Rosenblum , Stephen Sayles III , Sinsi Hernandez-Cancio This article has a correction. Please

2014 American Academy of Pediatrics

139. An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome

An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome | European Respiratory Society Main menu User menu Search Search for this keyword Search for this keyword An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome Keith C. Meyer , Ganesh (...) Great Ormond Street Hospital for Children , London , UK Kevin C. Wilson Boston University Medical Center , Boston, MA , USA Jan Brozek McMaster University , Hamilton, ON , Canada Allan R. Glanville The Lung Transplant Unit, St Vincents Hospital , Sydney , Australia A full list of the ISHLT/ATS/ERS BOS Task Force Committee members and their affiliations can be found in the Acknowledgements section Abstract Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation

2014 International Society for Heart and Lung Transplantation

140. Effect of oximetry on hospitalization in bronchiolitis: a randomized clinical trial. (Full text)

Effect of oximetry on hospitalization in bronchiolitis: a randomized clinical trial. Routine use of pulse oximetry has been associated with changes in bronchiolitis management and may have lowered the hospitalization threshold for patients with bronchiolitis.To examine if infants with bronchiolitis whose displayed oximetry measurements have been artificially elevated 3 percentage points above true values experience hospitalization rates at least 15% lower compared with infants with true values (...) displayed.Randomized, double-blind, parallel-group trial conducted from 2008 to 2013 in a tertiary-care pediatric emergency department in Toronto, Ontario, Canada. Participants were 213 otherwise healthy infants aged 4 weeks to 12 months with mild to moderate bronchiolitis and true oxygen saturations of 88% or higher.Pulse oximetry measurements with true saturation values displayed or with altered saturation values displayed that have been increased 3 percentage points above true values.The primary outcome

2014 JAMA Controlled trial quality: predicted high PubMed abstract