Latest & greatest articles for bronchiolitis

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Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

101. Antibiotics for bronchiolitis in children.

Antibiotics for bronchiolitis in children. BACKGROUND: Bronchiolitis is a serious, potentially life-threatening respiratory illness commonly affecting young babies. It is most often caused by Respiratory Syncytial Virus (RSV). The diagnosis is usually made on clinical grounds (especially tachypnoea and wheezing in a child less than two years of age). Antibiotics are not recommended for bronchiolitis unless there is concern about complications such as secondary bacterial pneumonia. Despite (...) this, they are used at rates of 34 to 99% in uncomplicated cases. OBJECTIVES: To evaluate the use of antibiotics for bronchiolitis. SEARCH STRATEGY: We searched the following electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL) which includes the Acute Respiratory Infection Groups' specialised register, the Database of Abstracts of Reviews of Effects (DARE) (The Cochrane Library Issue 3, 2006); MEDLINE (January 1966 to August Week 2, 2006); EMBASE (1990 to March 2006); and Current

Cochrane2007

102. Efficacy of interventions for bronchiolitis in critically ill infants: A systematic review and meta-analysis

Efficacy of interventions for bronchiolitis in critically ill infants: A systematic review and meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2007

103. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis.

A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. 17652648 2007 07 26 2007 07 31 2013 11 21 1533-4406 357 4 2007 Jul 26 The New England journal of medicine N. Engl. J. Med. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. 331-9 Bronchiolitis, the most common infection of the lower respiratory tract in infants, is a leading cause of hospitalization in childhood. Corticosteroids are commonly used to treat bronchiolitis, but evidence (...) of their effectiveness is limited. We conducted a double-blind, randomized trial comparing a single dose of oral dexamethasone (1 mg per kilogram of body weight) with placebo in 600 children (age range, 2 to 12 months) with a first episode of wheezing diagnosed in the emergency department as moderate-to-severe bronchiolitis (defined by a Respiratory Distress Assessment Instrument score > or =6). We enrolled patients at 20 emergency departments during the months of November through April over a 3-year period

NEJM2007

104. Bronchiolitis.

Bronchiolitis. Bronchiolitis is a distressing, potentially life-threatening respiratory condition that affects young babies. Around 2-3% of all infants younger than 1 year are admitted to hospital with bronchiolitis, usually during the seasonal epidemic. The majority of these infants are infected with respiratory syncytial virus and all have an intense inflammatory response in their airways. Although most infants recover, they have an increased risk of recurrent wheezing. Although bronchiolitis (...) is common, little is known about what causes infants to be susceptible. Diagnostic interventions have little effect on clinical outcome, and apart from supportive measures, there is no specific treatment. Bronchiolitis therefore presents an intriguing clinical conundrum and a major challenge to researchers. High quality clinical studies are needed to clarify assessment of disease severity and criteria for hospital admission, particularly the use of pulse oximetry and chest radiography. Careful mapping

Lancet2006

105. Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis

Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your (...) user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis Article Text Therapeutics Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute

Evidence-Based Medicine (Requires free registration)2006

106. Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants

Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2006

107. Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective

Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective Article Text Therapeutics Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective Free James D Kellner , MD Statistics from Altmetric.com

Evidence-Based Medicine (Requires free registration)2005

108. Is nasogastric fluid therapy a safe alternative to the i.v. route in infants with bronchiolitis?

Is nasogastric fluid therapy a safe alternative to the i.v. route in infants with bronchiolitis? BestBets: Is nasogastric fluid therapy a safe alternative to the i.v. route in infants with bronchiolitis? Is nasogastric fluid therapy a safe alternative to the i.v. route in infants with bronchiolitis? Report By: Neil Kennedy - SpR Paediatrics Search checked by Nuala Flanagan - SpR Paediatrics Institution: Royal Belfast Hospital for Sick Children Date Submitted: 7th September 2004 Date Completed (...) : 10th March 2005 Last Modified: 10th March 2005 Status: Green (complete) Three Part Question In [infants with bronchiolitis who need maintenance or replacement fluid therapy] is [administration of fluid by NG tube compared to IV infusion] [cause more respiratory difficulty or electrolyte disturbance] Clinical Scenario It is mid-December. As a paediatric SHO working a busy evening shift in a district general hospital, you are called to re-site the iv cannula of an infant with bronchiolitis

BestBETS2005

109. Are methylxanthines effective in preventing or reducing apnoeic spells in infants with bronchiolitis?

Are methylxanthines effective in preventing or reducing apnoeic spells in infants with bronchiolitis? BestBets: Are methylxanthines effective in preventing or reducing apnoeic spells in infants with bronchiolitis? Are methylxanthines effective in preventing or reducing apnoeic spells in infants with bronchiolitis? Report By: Pavanasam Ramesh, Martin Samuels - Staff Grade and Consultant Paediatrician respectively Search checked by Bob Phillips - Section Editor Archimedes, Archives of Disease (...) in Childhood Institution: University Hospital of North Staffordshire Date Submitted: 10th March 2005 Date Completed: 10th March 2005 Last Modified: 10th March 2005 Status: Green (complete) Three Part Question In [infants with bronchiolitis] does [caffeine] [reduce or prevent apnoeas]? Clinical Scenario A 2-week-old infant, born at 36 weeks gestation was admitted to the paediatric ward in November with a 24h history of runny nose, cough and episodes of shallow breathing and apnoeas. This was thought

BestBETS2005

110. Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchiolitis.

Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchiolitis. BACKGROUND: Respiratory syncytial virus (RSV) bronchiolitis is the most prevalent acute wheezing disorder in infants and is associated with recurrent wheeze and asthma in childhood. Interleukin 9, a type 2 cytokine has been proposed as a key cytokine in susceptibility to asthma. We aimed to investigate whether interleukin 9 was produced in the lungs of infants with severe RSV disease and (...) if found, from which cells it originated. METHODS: We did 150 non-bronchoscopic bronchoalveolar lavages during the course of ventilation in 24 term infants and 21 preterm infants ventilated for RSV bronchiolitis. We also did 10 bronchoalveolar lavages on the day of intubation in 10 control infants ventilated for non-respiratory causes. We measured pulmonary interleukin 9 mRNA and protein in samples from all groups. We used immunostaining to identify the cells that produce interleukin 9. FINDINGS

Lancet2004

111. Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis

Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis Davison C, Ventre K M, Luchetti M, Randolph A G CRD summary This review assessed treatments for critically ill infants with bronchiolitis. The authors concluded (...) that, currently, no treatment has been shown to be clearly effective, although surfactant appears promising and corticosteroids or ribavarin may be of benefit. There were some limitations to the review but, overall, the authors' cautious conclusions reflect the evidence. Authors' objectives To assess the efficacy of medical treatments for critically ill infants with bronchiolitis. Searching PubMed was searched from inception to October 2003 for studies reported in any language; the search terms were reported

DARE.2004

112. Glucocorticoids for acute viral bronchiolitis in infants and young children.

Glucocorticoids for acute viral bronchiolitis in infants and young children. BACKGROUND: Systemic glucocorticoids have been widely prescribed for use in infants and young children with acute viral bronchiolitis but the actual benefit of this intervention requires clarification. OBJECTIVES: To systematically review the evidence on the effectiveness of systemic glucocorticoids for the treatment of infants and young children with acute viral bronchiolitis. SEARCH STRATEGY: Multiple strategies were (...) were included if participants were diagnosed with acute viral bronchiolitis and treated with systemic (oral, intramuscular or intravenous) corticosteroids. Three reviewers independently selected potentially relevant articles. Four reviewers evaluated these studies, determined eligibility and assessed the methodological quality of each RCT. DATA COLLECTION AND ANALYSIS: The primary outcome of interest was length of hospital stay (LOS). Secondary outcomes were: respiratory rate, haemoglobin oxygen

Cochrane2004

113. Management of bronchiolitis in infants and children

Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Vishwanathan M, King V J, Bordley C, Honeycutt A A, Wittenborn J, Jackman A M, Sutton S F, Lohr K N CRD summary This review assessed the management (diagnosis, treatment, prophylaxis) of bronchiolitis in infants and children. The authors concluded that there is insufficient evidence to recommend any of the treatment assessed over good (...) supportive care. The authors' conclusions are consistent with the evidence reviewed, and are likely to be robust. Authors' objectives To assess the effectiveness of diagnostic tools, pharmaceutical therapies and prophylactic therapies, and the cost-effectiveness of prophylactic treatment, in the management of bronchiolitis in infants and children. This abstract focused upon the diagnosis and treatment of existing bronchiolitis in infants and children. Searching MEDLINE, the Cochrane Library and HEED were

DARE.2003

114. Management of bronchiolitis in infants and children

Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Viswanathan M, King V, Bordley C Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Viswanathan M, King V, Bordley C. Management of bronchiolitis in infants and children. Rockville (...) : Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 69. 2003 Authors' objectives This systematic review seeks to clarify the existing knowledge base for the management of bronchiolitis and offers directions for future research. Specifically, the review addresses the effectiveness of appropriate diagnostic tools, the effectiveness of pharmaceutical therapies for treating bronchiolitis, the role of prophylactic therapy for prevention of bronchiolitis

Health Technology Assessment (HTA) Database.2003

115. A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis.

A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2003

116. A multicenter, randomized, double-blind, controlled trial of nebulized epinephrine in infants with acute bronchiolitis.

A multicenter, randomized, double-blind, controlled trial of nebulized epinephrine in infants with acute bronchiolitis. 12840089 2003 07 03 2003 07 08 2013 11 21 1533-4406 349 1 2003 Jul 03 The New England journal of medicine N. Engl. J. Med. A multicenter, randomized, double-blind, controlled trial of nebulized epinephrine in infants with acute bronchiolitis. 27-35 The treatment of infants with bronchiolitis is largely supportive. The role of bronchodilators is controversial. Most studies (...) of the use of bronchodilators have enrolled small numbers of subjects and have examined only short-term outcomes, such as clinical scores. We conducted a randomized, double-blind, controlled trial comparing nebulized single-isomer epinephrine with placebo in 194 infants admitted to four hospitals in Queens-land, Australia, with a clinical diagnosis of bronchiolitis. Three 4-ml doses of 1 percent nebulized epinephrine or three 4-ml doses of normal saline were administered at four-hour intervals after

NEJM2003

117. Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant.

Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. BACKGROUND: In May 2000, eight persons who had formerly worked at a microwave-popcorn production plant were reported to have severe bronchiolitis obliterans. No recognized cause was identified in the plant. Therefore, we medically evaluated current employees and assessed their occupational exposures. METHODS: Questionnaire responses and spirometric findings in participating workers were compared with data from the third (...) of chronic cough and shortness of breath, according to comparisons with the national data, and twice the expected rates of physician-diagnosed asthma and chronic bronchitis. Overall, the workers had 3.3 times the expected rate of airway obstruction; those who had never smoked had 10.8 times the expected rate. Workers directly involved in the production of microwave popcorn had higher rates of shortness of breath on exertion and skin problems that had developed since they started work than workers

NEJM2002

118. Heliox Therapy in Infants With Acute Bronchiolitis

Heliox Therapy in Infants With Acute Bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2002

119. A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis

A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2002

120. Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis]

Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Fily A Authors (...) ' objectives To synthesise the evidence on the efficacy of various types of bronchodilators for the treatment of acute bronchiolitis in infants. Searching MEDLINE, HealthSTAR, EMBASE, Pascal and the Cochrane Library were all searched using the keywords 'bronchodilators', 'bronchiolitis' and 'childhood'. Only articles published between 1975 and 2000 in English or French were retained. Study selection Study designs of evaluations included in the review The studies needed to be comparative, prospective

DARE.2001