Latest & greatest articles for bronchiolitis

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on bronchiolitis or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on bronchiolitis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

21. Effect of Nebulized Hypertonic Saline Treatment in Emergency Departments on the Hospitalization Rate for Acute Bronchiolitis: A Randomized Clinical Trial

Effect of Nebulized Hypertonic Saline Treatment in Emergency Departments on the Hospitalization Rate for Acute Bronchiolitis: A Randomized Clinical Trial 28586918 2017 06 06 2017 06 06 2168-6211 2017 Jun 05 JAMA pediatrics JAMA Pediatr Effect of Nebulized Hypertonic Saline Treatment in Emergency Departments on the Hospitalization Rate for Acute Bronchiolitis: A Randomized Clinical Trial. e171333 10.1001/jamapediatrics.2017.1333 Acute bronchiolitis is the leading cause of hospitalization among (...) infants. Previous studies, underpowered to examine hospital admission, have found a limited benefit of nebulized hypertonic saline (HS) treatment in the pediatric emergency department (ED). To examine whether HS nebulization treatment would decrease the hospital admission rate among infants with a first episode of acute bronchiolitis. The Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis (GUERANDE) study was a multicenter, double-blind randomized clinical trial on 2 parallel groups

EvidenceUpdates2017

22. Is Nebulized Hypertonic Saline Solution Effective for Acute Bronchiolitis?

Is Nebulized Hypertonic Saline Solution Effective for Acute Bronchiolitis? DEFINE_ME_WA This site requires Cookies to be enabled to function. Please ensure Cookies are turned on and then re-visit the desired page.

Annals of Emergency Medicine Systematic Review Snapshots2017

23. High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial.

High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial. BACKGROUND: Bronchiolitis is the most common lung infection in infants and treatment focuses on management of respiratory distress and hypoxia. High-flow warm humidified oxygen (HFWHO) is increasingly used, but has not been rigorously studied in randomised trials. We aimed to examine whether HFWHO provided enhanced respiratory (...) support, thereby shortening time to weaning off oxygen. METHODS: In this open, phase 4, randomised controlled trial, we recruited children aged less than 24 months with moderate bronchiolitis attending the emergency department of the John Hunter Hospital or the medical unit of the John Hunter Children's Hospital in New South Wales, Australia. Patients were randomly allocated (1:1) via opaque sealed envelopes to HFWHO (maximum flow of 1 L/kg per min to a limit of 20 L/min using 1:1 air-oxygen ratio

Lancet2017

25. Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD)

Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD)

DynaMed Plus2017

26. Viral bronchiolitis.

Viral bronchiolitis. Viral bronchiolitis is a common clinical syndrome affecting infants and young children. Concern about its associated morbidity and cost has led to a large body of research that has been summarised in systematic reviews and integrated into clinical practice guidelines in several countries. The evidence and guideline recommendations consistently support a clinical diagnosis with the limited role for diagnostic testing for children presenting with the typical clinical syndrome (...) of viral upper respiratory infection progressing to the lower respiratory tract. Management is largely supportive, focusing on maintaining oxygenation and hydration of the patient. Evidence suggests no benefit from bronchodilator or corticosteroid use in infants with a first episode of bronchiolitis. Evidence for other treatments such as hypertonic saline is evolving but not clearly defined yet. For infants with severe disease, the insufficient available data suggest a role for high-flow nasal cannula

Lancet2016

27. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27144864 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 May 5;374(18):1793-4. doi: 10.1056/NEJMc1601509. Viral Bronchiolitis in Children. . Comment in [N Engl J Med. 2016] [N Engl J Med. 2016] Comment on [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] PMID: 27144864 DOI: [Indexed for MEDLINE] Free full text Publication types MeSH terms Full Text Sources Medical PubMed

NEJM2016

28. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27144865 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 May 5;374(18):1791. doi: 10.1056/NEJMc1601509#SA1. Viral Bronchiolitis in Children. 1 , 2 , 3 . 1 University of Tennessee College of Medicine, Memphis, TN jdevincenzo@uthsc.edu. 2 State University of New York at Stony Brook School of Medicine, Stony Brook, NY. 3 Northwestern University Feinberg School of Medicine, Chicago, IL. Comment in [N Engl J Med. 2016] Comment on [N

NEJM2016 Full Text: Link to full Text with Trip Pro

29. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27144866 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 May 5;374(18):1791-2. doi: 10.1056/NEJMc1601509#SA2. Viral Bronchiolitis in Children. 1 , 1 , 1 . 1 Columbia University Medical Center, New York, NY tc2625@cumc.columbia.edu. Comment in [N Engl J Med. 2016] Comment on [N Engl J Med. 2016] PMID: 27144866 DOI: [Indexed for MEDLINE] Publication types MeSH terms Full Text Sources Medical PubMed Commons 0 comments How to cite

NEJM2016 Full Text: Link to full Text with Trip Pro

30. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27144867 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 May 5;374(18):1792. doi: 10.1056/NEJMc1601509#SA3. Viral Bronchiolitis in Children. 1 . 1 Oregon Health and Science University, Portland, OR wallm@ohsu.edu. Comment in [N Engl J Med. 2016] Comment on [N Engl J Med. 2016] PMID: 27144867 DOI: [Indexed for MEDLINE] Publication types MeSH terms Full Text Sources Medical PubMed Commons 0 comments How to cite this comment

NEJM2016 Full Text: Link to full Text with Trip Pro

31. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27144868 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 May 5;374(18):1792-3. doi: 10.1056/NEJMc1601509#SA4. Viral Bronchiolitis in Children. 1 , 1 , 2 . 1 Istituto Giannina Gaslini, Genoa, Italy giovannirossi@gaslini.org. 2 University of Miami, Miami, FL. Erratum in [N Engl J Med. 2016] Comment in [N Engl J Med. 2016] Comment on [N Engl J Med. 2016] PMID: 27144868 DOI: [Indexed for MEDLINE] Publication types MeSH terms Full

NEJM2016 Full Text: Link to full Text with Trip Pro

32. Viral Bronchiolitis in Children.

Viral Bronchiolitis in Children. Viral Bronchiolitis in Children. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26735994 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add (...) to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 Jan 7;374(1):62-72. doi: 10.1056/NEJMra1413456. Viral Bronchiolitis in Children. . Comment in [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] [N Engl J Med. 2016] PMID: 26735994 DOI: [Indexed for MEDLINE] Publication type MeSH terms Substance Full Text Sources Medical PubMed Commons 0 comments How to cite this comment: Supplemental

NEJM2016

33. Systematic review with meta analysis: Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis

Systematic review with meta analysis: Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis Article Text

Evidence-Based Medicine (Requires free registration)2016

34. Bronchiolitis of Infancy Discharge Study (BIDS): a multicentre, parallel-group, double-blind, randomised controlled, equivalence trial with economic evaluation

Bronchiolitis of Infancy Discharge Study (BIDS): a multicentre, parallel-group, double-blind, randomised controlled, equivalence trial with economic evaluation Bronchiolitis of Infancy Discharge Study (BIDS): a multicentre, parallel group, double-blind, randomised controlled, equivalence trial with economic evaluation Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found (...) . Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} This study found that a permissive hypoxaemic oxygen saturation target of ≥ 90% for infants with acute viral bronchiolitis was as safe and clinically effective as a standard normoxic oxygen saturation target of ≥ 94%, with the lower oxygen saturation target dominating the economic analysis. {{author

NIHR HTA programme2015

35. Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review

Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose (...) a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} The study found that the use of hypertonic saline in infants with acute bronchiolitis had no clinical benefit on the length of hospital stay or readiness for discharge and was not found to be a cost-effective treatment. {{author}} {{($index , , , , , , , , , , , , , , , , , , , , & . Mark L Everard, 1 Daniel Hind

NIHR HTA programme2015

36. Budesonide/Formoterol for bronchiolitis obliterans after hematopoietic stem cell transplantation

Budesonide/Formoterol for bronchiolitis obliterans after hematopoietic stem cell transplantation 25835160 2015 06 02 2015 08 17 2015 11 19 1535-4970 191 11 2015 Jun 01 American journal of respiratory and critical care medicine Am. J. Respir. Crit. Care Med. Budesonide/Formoterol for bronchiolitis obliterans after hematopoietic stem cell transplantation. 1242-9 10.1164/rccm.201410-1818OC Systemic steroids are the standard treatment for bronchiolitis obliterans syndrome (BOS) after allogeneic (...) Research Support, Non-U.S. Gov't United States Am J Respir Crit Care Med 9421642 1073-449X 0 Bronchodilator Agents 0 Ethanolamines 51333-22-3 Budesonide W34SHF8J2K Formoterol Fumarate AIM IM Am J Respir Crit Care Med. 2015 Jun 1;191(11):1214-6 26029830 Adult Bronchiolitis Obliterans therapy Bronchodilator Agents therapeutic use Budesonide therapeutic use Double-Blind Method Ethanolamines therapeutic use Female Forced Expiratory Volume drug effects Formoterol Fumarate Hematopoietic Stem Cell

EvidenceUpdates2015

37. Randomised controlled trial: The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear

Randomised controlled trial: The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear Article Text Therapeutics/Prevention Randomised controlled trial The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear Free Jay Pershad Statistics from Altmetric.com No Altmetric data available for this article

Evidence-Based Medicine (Requires free registration)2015

38. Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia

Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your (...) user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Article Text Therapeutics/Prevention Randomised controlled trial Pulse oximetry may lead to unnecessary hospital admissions for infants

Evidence-Based Medicine (Requires free registration)2015

39. Bronchiolitis in children: diagnosis and management

Bronchiolitis in children: diagnosis and management Bronchiolitis in children: diagnosis and Bronchiolitis in children: diagnosis and management management NICE guideline Published: 1 June 2015 nice.org.uk/guidance/ng9 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration (...) be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Bronchiolitis in children: diagnosis and management (NG9) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 32Contents Contents Overview 5 Who

National Institute for Health and Clinical Excellence - Clinical Guidelines2015

40. Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis

Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Article Text Therapeutics/Prevention Randomised controlled trial Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Todd A Florin Statistics from Altmetric.com

Evidence-Based Medicine (Requires free registration)2015