Latest & greatest articles for bronchiolitis

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This page lists the very latest high quality evidence on bronchiolitis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

181. Haemophilus influenzae oral vaccination against acute bronchitis. Full Text available with Trip Pro

Haemophilus influenzae oral vaccination against acute bronchitis. To assess the effects of an oral whole cell nontypeable Haemophilus influenzae (NTHi) vaccine in protecting against recurrent episodes of bronchitis.We searched the Cochrane trials register, MEDLINE, Extramed, ISI Current Contents, Carl Uncover and contacted investigators of the studies.Randomised trials comparing the effects of an oral monobacterial NTHi vaccine on patients with recurrent exacerbations of bronchitis were (...) included when there was overt matching of the vaccine and placebo groups on clinical grounds.Two reviewers extracted data and assessed trial quality independently from original records and publications for incidence and severity of bronchitis episodes and carriage rate of nontypeable Haemophilus influenzae in the upper respiratory tract every three months following vaccination.Six trials were included in the study with a total of 440 participants. Oral vaccination using a monobacterial whole cell

2000 Cochrane

182. Antibiotics for acute bronchitis. Full Text available with Trip Pro

Antibiotics for acute bronchitis. Antibiotic treatment of acute bronchitis, which is one of the most common illnesses seen in primary care, is controversial. Most clinicians prescribe antibiotics in spite of expert recommendations against this practice.People with acute bronchitis may show little evidence of bacterial infection. If effective, antibiotics could shorten the course of the disease. However if they are not effective, the risk of antibiotic resistance may be increased. The objective (...) to 0.79), or to have abnormal lung findings (odds ratio 0.33, 95% confidence interval 0.13 to 0.86), and had a more rapid return to work or usual activities (weighted mean difference 0.7 days earlier, 95% confidence interval 0.2 to 1. 3). Antibiotic-treated patients reported significantly more adverse effects (odds ratio 1.64; 1.05 to 2.57) such as nausea, vomiting, headache, skin rash or vaginitis.Antibiotics appear to have a modest beneficial effect in the treatment of acute bronchitis

2000 Cochrane

183. Economic evaluation of ciprofloxacin compared with usual antibacterial care for the treatment of acute exacerbations of chronic bronchitis in patients followed for 1 year

Economic evaluation of ciprofloxacin compared with usual antibacterial care for the treatment of acute exacerbations of chronic bronchitis in patients followed for 1 year Economic evaluation of ciprofloxacin compared with usual antibacterial care for the treatment of acute exacerbations of chronic bronchitis in patients followed for 1 year Economic evaluation of ciprofloxacin compared with usual antibacterial care for the treatment of acute exacerbations of chronic bronchitis in patients (...) followed for 1 year Torrance G, Walker V, Grossman R, Mukherjee J, Vaughan D, La Forge J, Lampron N Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Use of ciprofloxacin for the treatment of acute exacerbations of chronic bronchitis

1999 NHS Economic Evaluation Database.

184. Antibiotics in acute bronchitis: a meta-analysis

Antibiotics in acute bronchitis: a meta-analysis Antibiotics in acute bronchitis: a meta-analysis Antibiotics in acute bronchitis: a meta-analysis Bent S, Saint S, Vittinghoff E, Grady D Authors' objectives To assess the effectiveness of antibiotics in the treatment of acute bronchitis. Searching The authors searched the MEDLINE electronic database (January 1966 to April 1998) using the search terms: 'bronchitis, drug therapy' and 'xs acute disease'. The reference lists of retrieved articles (...) (erythromycin, doxycycline, trimethoprim/sulfamethoxazole) for the intervention group and placebo for the control group. Duration of therapy in included studies was at least 5 days. Participants included in the review Otherwise healthy patients with acute bronchitis, no previous history of chronic lung disease, and pneumonia excluded by chest radiograph or clinical exam. Outcomes assessed in the review The duration of cough and sputum production and days lost from work. How were decisions on the relevance

1999 DARE.

185. Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis

Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis Destache C J, Dewan N, O'Donohue W J, Campbell J C, Angelillo V A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Antibiotic therapy in the treatment of acute exacerbation of chronic bronchitis (AECB) in patients with a diagnosis of chronic obstructive pulmonary disease (COPD) and chronic bronchitis episodes. The empirical antibiotic treatments selected were classified as first-line agents including amoxycillin, co-trimoxazole

1999 NHS Economic Evaluation Database.

186. Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial.

Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1999 PedsCCM Evidence-Based Journal Club

187. A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group

A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute (...) exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group Grossman R, Mukherjee J, Vaughan D, Eastwood C, Cook R, LaForge J, Lampron N Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use

1998 NHS Economic Evaluation Database.

188. The Use of Albuterol in Hospitalized Infants With Bronchiolitis

The Use of Albuterol in Hospitalized Infants With Bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1998 PedsCCM Evidence-Based Journal Club

189. Helium-oxygen improves Clinical Asthma Scores in children with acute bronchiolitis

Helium-oxygen improves Clinical Asthma Scores in children with acute bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1998 PedsCCM Evidence-Based Journal Club

190. Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis

Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis Flores G, Horwitz R I Authors' objectives To evaluate the efficacy of beta2-agonists as bronchodilator therapy in bronchiolitis. Searching MEDLINE was searched up to January 1995 using 'bronchiolitis' and 'drug therapy' both as MeSH terms and as textwords. Additional (...) was not restricted by language. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) of inhaled beta2-agonists were included in the review. Studies which used outcomes evaluable only in a pulmonary laboratory were excluded. Specific interventions included in the review Bronchodilator therapy for bronchiolitis, specifically inhaled beta2-agonists (fenoterol and albuterol of varying dosages and number of doses). No specific comparator was required in the inclusion

1997 DARE.

191. Cost assessment of josamycin dispersible tablets used in short term treatment of acute bronchitis

Cost assessment of josamycin dispersible tablets used in short term treatment of acute bronchitis Cost assessment of josamycin dispersible tablets used in short term treatment of acute bronchitis Cost assessment of josamycin dispersible tablets used in short term treatment of acute bronchitis Allenet B, Lenne X, Lebrun T, Brambilla C, Raffi F, Scheimberg A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains (...) a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The short-term treatment of acute bronchitis. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised patients with acute bronchitis. Setting The setting was the community (general practitioners, GP). The economic study was carried out in France. Dates

1997 NHS Economic Evaluation Database.

192. Randomized double blind placebo controlled trial of prednisolone in children admitted to hospital with respiratory syncytial virus bronchiolitis

Randomized double blind placebo controlled trial of prednisolone in children admitted to hospital with respiratory syncytial virus bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1997 PedsCCM Evidence-Based Journal Club

193. Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: A randomized, controlled trial

Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: A randomized, controlled trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1997 PedsCCM Evidence-Based Journal Club

194. Effects of aerosolized surfactant in patients with stable chronic bronchitis: a prospective randomized controlled trial. (Abstract)

Effects of aerosolized surfactant in patients with stable chronic bronchitis: a prospective randomized controlled trial. Chronic bronchitis, estimated to affect more than 13 million adults in the United States, is characterized in part by retention of airway secretions, but no approved or effective therapy for airway mucus retention in patients with chronic bronchitis has been established. Surfactant reduces sputum adhesiveness, which contributes to difficulty in clearing secretions (...) -related improvement in sputum transport by cilia in patients with stable chronic bronchitis.

1997 JAMA Controlled trial quality: predicted high

195. Treatment of acute bronchitis in adults without underlying lung disease

Treatment of acute bronchitis in adults without underlying lung disease Treatment of acute bronchitis in adults without underlying lung disease Treatment of acute bronchitis in adults without underlying lung disease Mackay D N Authors' objectives To determine whether antibiotic and bronchodilator treatment of acute bronchitis in patients without underlying lung disease is efficacious. Searching MEDLINE was searched from 1966 to 1995 using 'Bronchitis' as the keyword. Additional material (...) was located by examining bibliographies of papers on bronchitis in adults, and by handsearching papers addressing the microorganisms causing acute bronchitis. Study selection Study designs of evaluations included in the review Nine double-blind, randomised controlled trials (RCTs) were included. Specific interventions included in the review Antibiotic treatments including doxycycline, trimethoprim, trimethoprim plus sulfamethoxazole, erythromycin, erythromycin ethylsuccinate. Treatments were given

1996 DARE.

196. Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis

Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Efficacy of bronchodilator therapy in bronchiolitis: a meta-analysis Kellner J D, Ohlsson A, Gadomski A M, Wang E E Authors' objectives To determine if bronchodilators are efficacious in treating bronchiolitis in infants. Searching MEDLINE was searched from January 1966 to September 1994, Excerpta Medica from January 1974 to November 1995), and Reference (...) Update on selected dates (November 8, 1993; June 29, 1994; and April 26, 1995), using the search terms (explode)'bronchiolitis' combined with 'albuterol', 'ipratropium', 'adrenergic agents' or 'bronchodilator agents'. Addition material was obtained by examining the authors' files and the bibliographies of all retrieved articles. Study selection Study designs of evaluations included in the review Randomised placebo-controlled trials were included. Specific interventions included in the review

1996 DARE.

197. Efficacy of Bronchodilator Therapy in Bronchiolitis: A Meta-analysis

Efficacy of Bronchodilator Therapy in Bronchiolitis: A Meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1996 PedsCCM Evidence-Based Journal Club

198. Dexamethasone in bronchiolitis: a randomised controlled trial.

Dexamethasone in bronchiolitis: a randomised controlled trial. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1996 PedsCCM Evidence-Based Journal Club

199. Dexamethasone in bronchiolitis: a randomised controlled trial. (Abstract)

Dexamethasone in bronchiolitis: a randomised controlled trial. Although corticosteroids are commonly prescribed in the treatment of bronchiolitis, there is no evidence on the efficacy of these drugs in this disorder. We designed a randomised, double-blind, prospective study to assess the efficacy of dexamethasone in infants with bronchiolitis who require hospital management.Infants younger than 12 months who had been admitted to hospital for an initial episode of wheezing, were randomly (...) was done. Our primary endpoints were the time to resolution of symptoms--defined as the number of assessments needed to reach oxygen saturation of more than 95% while receiving no supplemental oxygen, an accessory muscle score of 0, a wheeze score of 0 or 1, and resumption of normal feeding--and duration of oxygen therapy. Follow-up assessments were made 10-14 days after discharge by telephone. We used a proportional-hazards model for our survival analysis.197 infants presented with bronchiolitis

1996 Lancet Controlled trial quality: predicted high

200. Bronchodilator treatment in moderate asthma or chronic bronchitis: continuous or on demand? A randomised controlled study. Full Text available with Trip Pro

Bronchodilator treatment in moderate asthma or chronic bronchitis: continuous or on demand? A randomised controlled study. To examine the effect of bronchodilator treatment given continuously versus on demand on the progression of asthma and chronic bronchitis and to compare the long term effects of a beta 2 adrenergic drug (salbutamol) and an anticholinergic drug (ipratropium bromide).Two year randomised controlled prospective 'crossover' study in which patients were assigned to one of two (...) parallel treatment groups receiving continuous treatment or treatment on demand.29 general practices in the catchment area of the University of Nijmegen.223 patients aged greater than or equal to 30 with moderate airway obstruction due to asthma or chronic bronchitis, selected by their general practitioners.1600 micrograms salbutamol or 160 micrograms ipratropium bromide daily (113 patients) or salbutamol or ipratropium bromide only during exacerbations or periods of dyspnoea (110). No other pulmonary

1991 BMJ Controlled trial quality: uncertain