Latest & greatest articles for breast cancer

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Top results for breast cancer

121. Contemporary Hormonal Contraception and the Risk of Breast Cancer.

Contemporary Hormonal Contraception and the Risk of Breast Cancer. BACKGROUND: Little is known about whether contemporary hormonal contraception is associated with an increased risk of breast cancer. METHODS: We assessed associations between the use of hormonal contraception and the risk of invasive breast cancer in a nationwide prospective cohort study involving all women in Denmark between 15 and 49 years of age who had not had cancer or venous thromboembolism and who had not received (...) treatment for infertility. Nationwide registries provided individually updated information about the use of hormonal contraception, breast-cancer diagnoses, and potential confounders. RESULTS: Among 1.8 million women who were followed on average for 10.9 years (a total of 19.6 million person-years), 11,517 cases of breast cancer occurred. As compared with women who had never used hormonal contraception, the relative risk of breast cancer among all current and recent users of hormonal contraception was

NEJM2017

122. Sentinel Lymph Node Biopsy Pathology and 2-Year Postsurgical Recurrence of Breast Cancer in Kenyan Women

Sentinel Lymph Node Biopsy Pathology and 2-Year Postsurgical Recurrence of Breast Cancer in Kenyan Women ');//--> ');//--> Search in: Menu Captcha ASCO Family of Sites Journals Publications Education Other Sites 2318 Mill Road, Suite 800, Alexandria, VA 22314 © 2018 American Society of Clinical Oncology |

Journal of global oncology2017 Full Text: Link to full Text with Trip Pro

123. A feasibility study of neoadjuvant talazoparib for operable breast cancer patients with a germline BRCA mutation demonstrates marked activity

A feasibility study of neoadjuvant talazoparib for operable breast cancer patients with a germline BRCA mutation demonstrates marked activity ARTICLE OPEN A feasibility study of neoadjuvant talazoparib for operable breast cancer patients with a germlineBRCA mutation demonstrates marked activity J. K. Litton 1 , M. Scoggins 2 , D. L. Ramirez 1 , R. K. Murthy 1 , G. J. Whitman 2 , K. R. Hess 3 , B. E. Adrada 2 , S. L. Moulder 1 , C. H. Barcenas 1 , V. Valero 1 , J. Schwartz Gomez 1 , E (...) . A. Mittendorf 4 , A. Thompson 4 , T. Helgason 1 , G. B. Mills 5 , H. Piwnica-Worms 6 and B. K. Arun 1 This study was undertaken to determine the feasibility of enrolling breast cancer patients on a single-agent-targeted therapy trial before neoadjuvant chemotherapy. Speci?cally, we evaluated talazoparib in patients harboring a deleterious BRCA mutation (BRCA +). Patients with a germline BRCA mutation and=1cm, HER2-negative primary tumors were eligible. Study participants underwent a pretreatment biopsy, 2

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro

124. In Their Own Words: A Qualitative Study of Kenyan Breast Cancer Survivors’ Knowledge, Experiences, and Attitudes Regarding Breast Cancer Genetics

In Their Own Words: A Qualitative Study of Kenyan Breast Cancer Survivors’ Knowledge, Experiences, and Attitudes Regarding Breast Cancer Genetics ');//--> ');//--> Search in: Menu Captcha ASCO Family of Sites Journals Publications Education Other Sites 2318 Mill Road, Suite 800, Alexandria, VA 22314 © 2018 American Society of Clinical Oncology |

Journal of global oncology2017 Full Text: Link to full Text with Trip Pro

126. Fulvestrant (Faslodex) - Treatment of oestrogen receptor positive, locally advanced or metastatic breast cancer

Fulvestrant (Faslodex) - Treatment of oestrogen receptor positive, locally advanced or metastatic breast cancer Published 11 December 2017 Statement of Advice: fulvestrant 250 mg solution for injection (Faslodex ® ) SMC No 1294/17 AstraZeneca UK Limited 10 November 2017 ADVICE: in the absence of a submission from the holder of the marketing authorisation fulvestrant (Faslodex ® ) is not recommended for use within NHS Scotland. Indication under review: Treatment of oestrogen receptor positive (...) , locally advanced or metastatic breast cancer in postmenopausal women not previously treated with endocrine therapy. The holder of the marketing authorisation has not made a submission to SMC regarding this product in this setting. As a result we cannot recommend its use within NHSScotland. Advice context: No part of this advice may be used without the whole of the advice being quoted in full. This advice represents the view of the Scottish Medicines Consortium. It is provided to inform

Scottish Medicines Consortium2017

127. Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology?Cancer Care Ontario Focused Guideline Update

Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology?Cancer Care Ontario Focused Guideline Update | Cancer Care Ontario Google Tag Manager You are using an outdated browser. We suggest you update your browser for a better experience. for update. Browse Guidelines Browse Pathway Maps Sort by You are here / / Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology–Cancer Care Ontario Focused Guideline (...) Update Guidelines & Advice Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology–Cancer Care Ontario Focused Guideline Update ID: GL-1-A-2016-2 Oct 2017 Type of Content: Guidelines & Advice, Clinical Document Status: Current Authors: Catherine Van Poznak, Mark R. Somerfield, William E. Barlow, J. Sybil Biermann, Linda D. Bosserman, Mark J. Clemons, Sukhbinder K. Dhesy-Thind, Melissa S. Dillmon, Andrea Eisen, Elizabeth S. Frank, Reshma Jagsi, Rachel

Cancer Care Ontario2017

129. Effect of myofascial techniques for treatment of persistent arm pain after breast cancer treatment: randomized controlled trial

Effect of myofascial techniques for treatment of persistent arm pain after breast cancer treatment: randomized controlled trial 28914087 2017 09 15 1477-0873 2017 Sep 01 Clinical rehabilitation Clin Rehabil Effect of myofascial techniques for treatment of persistent arm pain after breast cancer treatment: randomized controlled trial. 269215517730863 10.1177/0269215517730863 To investigate the effect of myofascial therapy in addition to a standard physical therapy program for treatment (...) of persistent arm pain after finishing breast cancer treatment. Double-blinded (patient and assessor) randomized controlled trial. University Hospitals Leuven, Belgium. A total of 50 patients with persistent arm pain and myofascial dysfunctions after breast cancer treatment. Over three months, all patients received a standard physical therapy program. The intervention group received in addition 12 sessions of myofascial therapy, and the control group received 12 sessions of placebo therapy. Main outcome

EvidenceUpdates2017

130. Bevacizumab (Kyomarc) - for the treatment of cancer of the colon or rectum, breast cancer, non-small cell lung cancer (NSCLC), kidney cancer, cervical cancer, and cancer of the ovary, the fallopian tube, or the peritoneum.

Bevacizumab (Kyomarc) - for the treatment of cancer of the colon or rectum, breast cancer, non-small cell lung cancer (NSCLC), kidney cancer, cervical cancer, and cancer of the ovary, the fallopian tube, or the peritoneum.

European Medicines Agency - EPARs2017

131. Mesenchymal stem cells in breast cancer: response to chemical and mechanical stimuli

Mesenchymal stem cells in breast cancer: response to chemical and mechanical stimuli 158 www.impactjournals.com/oncoscience Oncoscience www.impactjournals.com/oncoscience/ Oncoscience, Vol. 4(11-12), November 2017 Mesenchymal stem cells in breast cancer: response to chemical and mechanical stimuli Seiichiro Ishihara, Suzanne M. Ponik, and Hisashi Haga The tumor microenvironment contains not only cancer cells but also non-cancerous cells and extracellular matrices (ECMs). These cell types (...) interact through chemical and mechanical stimuli and as a result, regulate tumor progression. While many studies have identified chemical stimuli that are critical for cancer progression, the role of mechanical stimuli is less defined. It has been recently shown that mechanical stimuli, especially the stiffness of ECMs, contribute to tumor progression in some specific cancers including breast, colorectal, and lung [1, 2, 3]. In particular, cancer cells respond to stiffness of surrounding ECMs

Oncoscience2017 Full Text: Link to full Text with Trip Pro

132. Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy

Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy ARTICLE OPEN Molecular changes in premenopausal oestrogen receptor- positive primary breast cancer in Vietnamese women after oophorectomy Ben P. Haynes 1 , Ophira Ginsburg 2,3 , Qiong Gao 4 , Elizabeth Folkerd 1 , Maria Afentakis 1 , Le Hong Quang 5 , Pham Thi Han 6 , Pham Hong Khoa 5 , Nguyen Van Dinh 5 ,TaVanTo 6 , Mark Clemons 7 , Ian E. Smith 8 and Mitch Dowsett 1,4 (...) For premenopausal women with primary ER+breast cancer, oophorectomy (OvX) is an evidence-based cost-effective option and is standard treatment in many countries. However, there is virtually no data describing the effects of OvX on breast tumour biology. We therefore, characterised the endocrine and genome-wide transcriptional impact of OvX in 56 premenopausal women with ER+ breastcancerfor2weekspriortomastectomy.Plasmaestradiolconcentrationsdecreasedfrom406±41to20.7±2.6pmol/l(mean ±sem) 24h after OvX

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro

133. PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells

PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells ARTICLE OPEN PTK6 regulates growth and survival of endocrine therapy- resistant ER+ breast cancer cells Koichi Ito 1 , Sun Hee Park 1 , Igor Katsyv 2 , Weijia Zhang 3 , Carmine De Angelis 4,5 , Rachel Schiff 4,5,6 and Hanna Y. Irie 1,7 The non-receptor tyrosine kinase, PTK6/BRK, is highly expressed in multiple tumor types, including prostate, ovarian, and breast cancers, and regulates oncogenic phenotypes (...) such as proliferation, migration, and survival. PTK6 inhibition also overcomes targeted therapy resistance of HER2+ breast cancer. Although PTK6 is highly expressed in ER+ Luminal breast cancers, the role of PTK6 in this subtype has not been elucidated. In this study, we investigated the functions of PTK6 in ER+ Luminal breast cancer cells, including those that are relatively resistant to estrogen deprivation or targeted endocrine therapies used in the treatment of ER+ cancers. Enhanced expression of PTK6 in ER

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro

134. Psychometric properties of the Beliefs about Medicine Questionnaire–adjuvant endocrine therapy (BMQ-AET) for women taking AETs following early-stage breast cancer

Psychometric properties of the Beliefs about Medicine Questionnaire–adjuvant endocrine therapy (BMQ-AET) for women taking AETs following early-stage breast cancer SAGE Journals: Your gateway to world-class journal research MENU Sign In Institution Society Access Options You can be signed in via any or all of the methods shown below at the same time. My Profile Sign in here to access free tools such as favourites and alerts, or to access personal subscriptions Email (required) Password

Health psychology open2017 Full Text: Link to full Text with Trip Pro

135. Knowledge Summaries for Comprehensive Breast Cancer Control

Knowledge Summaries for Comprehensive Breast Cancer Control ');//--> ');//--> Search in: Menu Captcha ASCO Family of Sites Journals Publications Education Other Sites 2318 Mill Road, Suite 800, Alexandria, VA 22314 © 2018 American Society of Clinical Oncology |

Journal of global oncology2017 Full Text: Link to full Text with Trip Pro

136. Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI

Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI | npj Breast Cancer Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer (...) ). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. A Nature Research Journal Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI , & , npj Breast Cancer volume 3 , Article number: 43 ( 2017 ) | Subjects Abstract Radiomics deals with the high throughput extraction of quantitative textural information from radiological images that not visually perceivable by radiologists. However

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro

137. Targeting immune checkpoints in breast cancer: an update of early results

Targeting immune checkpoints in breast cancer: an update of early results Targeting immune checkpoints in breast cancer: an update of early results | Esmo Open We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your (...) user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Targeting immune checkpoints in breast cancer: an update of early results Article Text Review Targeting immune checkpoints in breast cancer: an update of early results Cinzia Solinas , Andrea Gombos , Sofiya Latifyan , Martine Piccart-Gebhart , Marleen Kok

ESMO open2017 Full Text: Link to full Text with Trip Pro

138. Breast Cancer Pathology Turnaround Time in Botswana

Breast Cancer Pathology Turnaround Time in Botswana ');//--> ');//--> Search in: Menu Captcha ASCO Family of Sites Journals Publications Education Other Sites 2318 Mill Road, Suite 800, Alexandria, VA 22314 © 2018 American Society of Clinical Oncology |

Journal of global oncology2017 Full Text: Link to full Text with Trip Pro

139. A metastasis biomarker (MetaSite Breastâ„¢ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer

A metastasis biomarker (MetaSite Breastâ„¢ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer ARTICLE OPEN A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor- positive, HER2-negative early-stage breast cancer Joseph A. Sparano 1 , Robert Gray 2 , Maja H. Oktay 1 , David Entenberg 3 , Thomas Rohan 3 , Xiaonan Xue 3 , Michael Donovan 4 , Michael Peterson 5 , Anthony Shuber 5 (...) for tumor cells into the circulation. We evaluated primary tumors from 600 patients with Stage I–III breast cancer treated with adjuvant chemotherapy in trial E2197 (NCT00003519), plus endocrine therapy for hormone receptor (HR)+ disease. TMEM were identi?ed and enumerated using an analytically validated, fully automated digital pathology/image analysis method (MetaSite Breast™), hereafter referred to as MetaSite Score (MS). The objectives were to determine the association between MS and distant relapse

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro

140. Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk

Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk 29119134 2017 12 19 2374-4677 3 2017 NPJ breast cancer NPJ Breast Cancer Erratum: Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk. 44 10.1038/s41523-017-0046-2 [This corrects the article DOI: 10.1038/s41523-017-0024-8.]. Slavin Thomas P TP Department of Medical Oncology, Division (...) .410425.6 Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA USA. 0000 0004 0421 8357 grid.410425.6 Couch Fergus J FJ Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA. 0000 0004 0459 167X grid.66875.3a Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA. 0000 0004 0459 167X grid.66875.3a eng Published Erratum 2017 11 07 United States NPJ Breast Cancer 101674891 2374-4677 NPJ Breast Cancer. 2017 Jun 9;3:22 28649662

NPJ breast cancer2017 Full Text: Link to full Text with Trip Pro