Latest & greatest articles for breast cancer

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Top results for breast cancer

21. Improved sleep after Qigong exercise in breast cancer survivors: A pilot study. Full Text available with Trip Pro

Improved sleep after Qigong exercise in breast cancer survivors: A pilot study. Sleep disorder and fatigue are among a few major concerns of breast cancer survivors across the survivorship trajectory. The purpose of this pilot study was to examine feasibility and trends in multiple outcomes after a 6-week Qigong exercise program in breast cancer survivors.Eight female adults (mean age 55.4 ± 9.4 years, mean time after the completion of cancer treatment 3.9 ± 5.7 years) who had a diagnosis (...) of breast cancer and were at least 3 months postcompletion of primary cancer treatment prior to participation in this study. Baseline evaluation was administered using subjective questionnaires on sleep quality, insomnia, fatigue, and quality of life. All subjects participated in two training sessions to learn the "Six Healing Sound" Qigong exercise and attended group Qigong sessions once per week in the following 6 weeks. In addition to the group sessions, subjects were asked to perform the Qigong

2019 Asia-Pacific journal of oncology nursing Controlled trial quality: uncertain

22. A Comparative Study of Hypofractionated and Conventional Radiotherapy in Postmastectomy Breast Cancer Patients. Full Text available with Trip Pro

HF RT was found to be well tolerated with mild-to-moderate side effects that neither reached statistical significance nor warranted any treatment interruption/hospitalization.HF postmastectomy RT is comparable to conventional RT without evidence of higher adverse effects or inferior locoregional tumor control and has an added advantage of increased compliance because of short duration; hence, it can help in accommodating more breast cancer patients in a calendar year, ultimately resulting (...) A Comparative Study of Hypofractionated and Conventional Radiotherapy in Postmastectomy Breast Cancer Patients. The aim of this study was to compare toxicity and locoregional control of short duration hypofractionated (HF) radiotherapy (RT) with conventional RT in breast cancer patients.A total of 100 postmastectomy breast cancer patients were randomized for adjuvant RT in control group (comprising fifty patients who received the standard conventional dose of 50 Gy in 25 fractions with 2 Gy per

2019 Asia-Pacific journal of oncology nursing Controlled trial quality: uncertain

23. Effectiveness of Mindfulness-Based Art Therapy on Healthy Quality of Life in Women with Breast Cancer. Full Text available with Trip Pro

Effectiveness of Mindfulness-Based Art Therapy on Healthy Quality of Life in Women with Breast Cancer. The purpose of this study was to determine the effectiveness of mindfulness-based art therapy (MBAT) in promoting quality of life in Neyshabur women with breast cancer.This study was an interventional design that was conducted on 124 women with breast cancer (any stage) in Iran 2018. One hundred and fourteen women with breast cancer were paired by age and randomized to either 12-week MBAT (...) intervention group or a wait-list-control group. One hundred and fourteen women with breast cancer completed both the pre-and post-study measurements. As compared to the control group, the MBAT group demonstrated a significant decrease in symptoms of distress and significant improvements in key aspects of the health-related quality of life (as measured by the World Health Organization Quality-of-Life - BREF questionnaire).The MBAT interventions had a significant effect on improving quality of life

2019 Asia-Pacific journal of oncology nursing Controlled trial quality: uncertain

24. Neratinib for extended adjuvant treatment of hormone receptor-positive, HER2-positive early stage breast cancer after adjuvant trastuzumab

available. The cost-effectiveness estimates are uncertain, but within the range that NICE normally considers an acceptable use of NHS resources. Therefore, neratinib is recommended if trastuzumab is the only HER2-directed adjuvant treatment a person has had, and if they had chemotherapy-based treatment before surgery to reduce tumour size (neoadjuvant treatment) they still have signs of cancer (residual invasive disease) in tissue samples from the breast or armpit (axilla). The clinical trial did (...) stage breast cancer in adults who completed adjuvant trastuzumab-based therapy less than 1 year ago only if: trastuzumab is the only HER2-directed adjuvant treatment they have had, and if they had neoadjuvant chemotherapy-based regimens, they still had residual invasive disease in the breast or axilla following the neoadjuvant treatment, and the company provides neratinib according to the commercial arrangement. 1.2 This recommendation is not intended to affect treatment with neratinib

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

25. Ribociclib (breast cancer; combination with an aromatase inhibitor) - Addendum to Commission A19-06

of ribociclib + letrozole in comparison with letrozole. An added benefit for this outcome is therefore not proven. Morbidity Symptoms, recorded using the EORTC QLQ-C30 and the EORTC QLQ-BR23 (symptom scales) Symptom outcomes were recorded with the symptom scales of the disease-specific instruments European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30) and EORTC Quality of Life Questionnaire-Breast Cancer Module (QLQ-BR23). In each case (...) Ribociclib (breast cancer; combination with an aromatase inhibitor) - Addendum to Commission A19-06 1 Translation of addendum A19-46 Ribociclib (Mammakarzinom; Kombination mit einem Aromatasehemmer) – Addendum zum Auftrag A19-06 (Version 1.0; Status: 14 June 2019). Please note: This translation is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Addendum 14 June 2019 1.0 Commission: A19-46

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

26. Ribociclib (breast cancer; combination with fulvestrant) - Addendum to Commission A19-06

Ribociclib (breast cancer; combination with fulvestrant) - Addendum to Commission A19-06 1 Translation of addendum A19-45 Ribociclib (Mammakarzinom; Kombination mit Fulvestrant) – Addendum zum Auftrag A19-06 (Version 1.0; Status: 17 June 2019). Please note: This translation is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Addendum 17 June 2019 1.0 Commission: A19-45 Version: Status: IQWiG (...) Reports – Commission No. A19-45 Ribociclib (breast cancer; combination with fulvestrant) – Addendum to Commission A19-06 1 Addendum A19-45 Version 1.0 Ribociclib – Addendum to Commission A19-06 17 June 2019 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Ribociclib (breast cancer; combination with fulvestrant) – Addendum to Commission A19-06 Commissioning agency: Federal Joint Committee

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

27. Pertuzumab (Perjeta) after surgery for some breast cancers at high risk of recurrence

. In the neoadjuvant setting, i.e. before surgery, it has an unfavourable harm-benefit balance. Pertuzumab has also been authorised for use after surgery, in addition to trastuzumab and chemotherapy, in women with non-metastatic breast cancer overexpressing HER2 protein and at high risk of recurrence. NOT ACCEPTABLE Pertuzumab compared to placebo: survival rate the same and risk of invasive disease almost unchanged, but a higher risk of adverse effects, in particular heart failure. Full text available for free (...) Pertuzumab (Perjeta) after surgery for some breast cancers at high risk of recurrence Prescrire IN ENGLISH - Spotlight ''Sample Free Download article (titre court pour FB et Twitter)'', 1 December 2019 {1} {1} {1} | | > > > Sample Free Download article (titre court pour FB et Twitter) Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the December

2019 Prescrire

28. Aerobic and Resistance Exercise Improves Shoulder Function in Women Who Are Overweight or Obese and Have Breast Cancer: A Randomized Controlled Trial (Abstract)

Aerobic and Resistance Exercise Improves Shoulder Function in Women Who Are Overweight or Obese and Have Breast Cancer: A Randomized Controlled Trial Adverse upper limb musculoskeletal effects occur after surgical procedures and radiotherapy for breast cancer and can interfere with activities of daily living.The objective of this study was to examine the effects of a 16-week exercise intervention on shoulder function in women who are overweight or obese and have breast cancer.This study (...) was a randomized controlled trial.The study was performed at the Division of Biokinesiology and Physical Therapy at the University of Southern California.One hundred women with breast cancer were randomly allocated to exercise or usual-care groups. The mean (SD) age of the women was 53.5 (10.4) years, 55% were Hispanic white, and their mean (SD) body mass index was 33.5 (5.5) kg/m2.The 16-week exercise intervention consisted of supervised, progressive, moderate to vigorous aerobic and resistance exercise 3

2019 EvidenceUpdates

29. Ribociclib (Kisqali) - breast cancer

-based therapy for advanced breast cancer (subpopulation B, defined below). The key evidence for the use of ribociclib in combination with fulvestrant for the treatment of HR- positive/HER2-negative advanced breast cancer (which comprises metastatic and locally advanced disease not amenable to curative surgery) comes from MONALEESA-3, a phase III, double-blind, placebo-controlled, parallel group, international study. 2 The study included postmenopausal women with confirmed HR-positive/HER2-negative (...) advanced breast cancer. Patients had >1 measurable lesion per Response Evaluation Criteria In Solid Tumours (RECIST; version 1.1) or one predominantly lytic bone lesion, had an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1, with adequate organ and bone marrow function. 2 The study included two subpopulations, according to presence or absence of evidence of resistance to prior endocrine therapy: Subpopulation A: • Newly diagnosed advanced breast cancer (de novo), treatment naïve

2019 Scottish Medicines Consortium

30. Neratinib (Nerlynx) - breast cancer and solid tumours

Neratinib (Nerlynx) - breast cancer and solid tumours Terms of use - Canada.ca Language selection Search Search Canada.ca Search Topics menu Main Menu You are here: Terms of use From These Terms of Use govern the access and use of Clinical Information released by Health Canada for non-commercial purposes. By clicking the button “I agree” and accepting these Terms of Use and upon being granted access to the Clinical Information, you, and, if applicable, the organization on behalf of which you

2019 Health Canada - drugs and medical devices

31. Trastuzumab (Ogivri) - breast cancer or gastric cancer

Trastuzumab (Ogivri) - breast cancer or gastric cancer Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs written for approved after September 1

2019 Health Canada - Drug and Health Product Register

32. Adding Ovarian Suppression to Tamoxifen for Premenopausal Breast Cancer: A Randomized Phase III Trial (Abstract)

Adding Ovarian Suppression to Tamoxifen for Premenopausal Breast Cancer: A Randomized Phase III Trial The addition of ovarian function suppression (OFS) for 5 years to tamoxifen (TAM) for treatment of premenopausal patients with breast cancer after completion of chemotherapy has beneficial effects on disease-free survival (DFS). This study evaluated the efficacy of adding 2 years of OFS to TAM in patients with hormone receptor-positive breast cancer who remain in a premenopausal state or resume (...) ovarian function after chemotherapy.We enrolled 1,483 premenopausal women (age ≤ 45 years) with estrogen receptor-positive breast cancer treated with definitive surgery after completing adjuvant or neoadjuvant chemotherapy. Ovarian function was assessed every 6 months for 2 years since enrollment on the basis of follicular-stimulating hormone levels and vaginal bleeding history. If ovarian function was confirmed to be premenopausal at each visit, the patient was randomly assigned to complete 5 years

2019 EvidenceUpdates

33. Pyrotinib or Lapatinib Combined With Capecitabine in HER2-Positive Metastatic Breast Cancer With Prior Taxanes, Anthracyclines, and/or Trastuzumab: A Randomized, Phase II Study (Abstract)

Pyrotinib or Lapatinib Combined With Capecitabine in HER2-Positive Metastatic Breast Cancer With Prior Taxanes, Anthracyclines, and/or Trastuzumab: A Randomized, Phase II Study Pyrotinib, an irreversible pan-ErbB inhibitor, showed promising antitumor activity and acceptable tolerability in a phase I trial. We assessed the efficacy and tolerability of pyrotinib versus lapatinib, both in combination with capecitabine, in women with human epidermal growth factor receptor 2 (HER2)-positive (...) metastatic breast cancer in an open-label, multicenter, randomized phase II study.Chinese patients with HER2-positive relapsed or metastatic breast cancer previously treated with taxanes, anthracyclines, and/or trastuzumab were assigned (1:1) to receive 400 mg pyrotinib or lapatinib 1,250 mg orally once per day for 21-day cycles in combination with capecitabine (1,000 mg/m2 orally twice per day on days 1 to 14). The primary end point was investigator-assessed overall response rate per Response Evaluation

2019 EvidenceUpdates

34. Influence of delay on breast cancer surgery outcome

] OR breast carcinoma[Title/Abstract] OR breast carcinomas[Title/Abstract] OR breast tumour[Title/Abstract] OR breast tumours[Title/Abstract] OR breast tumor[Title/Abstract] OR breast tumors[Title/Abstract] OR breast malignancies[Title/Abstract] OR breast cancer[Title/Abstract] 4. 1 OR 2 OR 3 362699 Intervention: 5. "Time-to-Treatment"[Mesh] 6. "Time Factors"[Mesh] 7. wait time[Title/Abstract] OR waiting time[Title/Abstract] OR wait list[Title/Abstract] OR waiting list[Title/Abstract] OR wait scheme[Title (...) . breast NEAR/4 (neoplasm OR cancer OR carcinoma OR tumor OR malignancy)):ab,ti 4. 1 OR 2 OR 3 566756 Intervention: 5. 'therapy delay'/de 6. 'time to treatment'/de 7. 'timeliness'/de 8. 'time factor'/de 9. ((wait* NEAR/3 (time OR list OR scheme)):ab,ti) OR 'treatment delay':ab,ti OR 'delayed treatment':ab,ti OR (('time to' NEAR/1 (treatment OR therapy OR surgery)):ab,ti) OR 'time interval':ab,ti OR timeliness:ab,ti OR 'surgical delay':ab,ti OR 'delayed surgery':ab,ti 10. 5 OR 6 OR 7 OR 8 OR 9 130804

2019 Swedish Council on Technology Assessement

35. Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis Full Text available with Trip Pro

Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis Although international guidelines support the administration of hormone therapies with or without targeted therapies in postmenopausal women with hormone-receptor-positive, HER2-negative metastatic breast cancer, upfront use of chemotherapy remains common even in the absence of visceral crisis. Because first-line (...) trials investigating chemotherapy with or without targeted therapies and hormone therapies with or without targeted therapies as first-line or second-line treatments, or both, in postmenopausal women with hormone-receptor-positive, HER2-negative metastatic breast cancer, published between Jan 1, 2000, and Dec 31, 2017. Additional recently published randomised controlled trials relevant to the topic were also subsequently added. No language restrictions were adopted for our search. A Bayesian network

2019 EvidenceUpdates

36. Prosigna Gene Signature to Assess Expected Benefit from Chemotherapy in Breast Cancer. Assessment of manufacturer’s submission

Prosigna Gene Signature to Assess Expected Benefit from Chemotherapy in Breast Cancer. Assessment of manufacturer’s submission Prosigna Gene Signature to Assess Expected Benefit from Chemotherapy in Breast Cancer - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close Prosigna Gene Signature to Assess Expected Benefit from Chemotherapy in Breast (...) Cancer Order Download: Key message Background Breast cancer can be treated with chemotherapy, hormone therapy and radiation, or a combination of these to prevent the spread of cancer cells, after surgical removal of the tumor. When assessing whether a patient should be offered chemotherapy, information about prognosis is important. Patients at high risk of recurrence should be offered chemotherapy, while patients at low risk are not very likely to gain from such treatment, in which case side effects

2019 Norwegian Institute of Public Health

37. Combination Therapy for the Treatment of Adults with Any Stage Breast Cancer: Clinical Effectiveness and Guidelines

Combination Therapy for the Treatment of Adults with Any Stage Breast Cancer: Clinical Effectiveness and Guidelines Combination Therapy for the Treatment of Adults with Any Stage Breast Cancer: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Combination Therapy for the Treatment of Adults with Any Stage Breast Cancer: Clinical Effectiveness and Guidelines Combination Therapy for the Treatment of Adults with Any Stage Breast Cancer: Clinical Effectiveness (...) and Guidelines Last updated: February 5, 2019 Project Number: RB1307-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of combination therapy in adults with any stage of breast cancer? What are the evidence-based guidelines associated with the use of combination therapy in adults with any stage of breast cancer? Key Message Two systematic reviews (one with a meta-analysis), 15 non-randomized studies, and one

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

38. Sample Selection for Biomarker Testing in Adults with Breast Cancer: Guidelines

Sample Selection for Biomarker Testing in Adults with Breast Cancer: Guidelines Sample Selection for Biomarker Testing in Adults with Breast Cancer: Guidelines | CADTH.ca Find the information you need Sample Selection for Biomarker Testing in Adults with Breast Cancer: Guidelines Sample Selection for Biomarker Testing in Adults with Breast Cancer: Guidelines Last updated: February 6, 2019 Project Number: RB1305-000 Product Line: Research Type: Devices and Systems Report Type: Summary (...) of Abstracts Result type: Report Question What are the evidence-based guidelines regarding sample selection for biomarker testing to inform treatment decisions in adults with breast cancer? Key Message Four evidence-based guidelines were identified regarding sample selection for biomarker testing in adults with breast cancer. Files Rapid Response Summary of Abstracts Published : February 6, 2019 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

39. Preoperative Seed Placement for Breast Cancer Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Last updated: April 1, 2019 Project Number: RB1319-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of preoperative seed placement for patients undergoing surgery for breast cancer? What is the cost-effectiveness of preoperative seed placement for patients undergoing surgery for breast cancer? What are the evidence-based guidelines regarding methods of preoperative tumor localization for patient (...) Preoperative Seed Placement for Breast Cancer Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Preoperative Seed Placement for Breast Cancer Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Preoperative Seed Placement for Breast Cancer Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Preoperative Seed Placement for Breast Cancer Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

40. Gene Expression Profiling Tests for Breast Cancer: A Rapid Qualitative Review

Gene Expression Profiling Tests for Breast Cancer: A Rapid Qualitative Review Gene Expression Profiling Tests for Breast Cancer: A Rapid Qualitative Review | CADTH.ca Find the information you need Gene Expression Profiling Tests for Breast Cancer: A Rapid Qualitative Review Gene Expression Profiling Tests for Breast Cancer: A Rapid Qualitative Review Last updated: April 18, 2019 Project Number: RC1099-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical (...) Appraisal Result type: Report Question What are patients’ and clinicians’ expectations of gene expression profiling tests for breast cancer? How do patients and clinicians understand, communicate, and make decisions to undergo gene expression profiling testing for breast cancer? How do patients and clinicians understand, communicate and make decisions based on the results? How does the option, or not, of gene expression profile testing help to shape patients’, and clinicians’ experiences and perceptions

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review