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Latest & greatest articles for breast cancer screening
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Understanding recent trends in incidence of invasive breastcancer in Norway: age-period-cohort analysis based on registry data on mammography screening and hormone treatment use. OBJECTIVE: To quantify the separate contributions of menopausal hormone treatment and mammography screening activities on trends in incidence of invasive breastcancer between 1987 and 2008. DESIGN: Population study using aggregated data analysed by an extended age-period-cohort model. SETTING: Norway. Population (...) Norwegian women aged 30-90 between 1987 and 2008, including 50,102 newly diagnosed cases of invasive breastcancer. Main outcomes measures Attributable proportions of mammography screening and hormone treatment to recent incidence of invasive breastcancer, and the remaining variation in incidence after adjustment for mammography screening and hormone treatment. RESULTS: The incidence of invasive breastcancer in Norway increased steadily until 2002, levelled off, and then declined from 2006. All non
Recommendations on screening for breastcancer in average-risk women aged 40-74 years 22106103 2011 11 22 2012 01 19 2016 10 19 1488-2329 183 17 2011 Nov 22 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Recommendations on screening for breastcancer in average-risk women aged 40-74 years. 1991-2001 10.1503/cmaj.110334 Canadian Task Force on Preventive Health Care Alberta Kidney Disease Network, University of Alberta, Edmonton, Alta. Tonelli (...) (9310):909-19 11918907 CMAJ. 2012 May 15;184(8):921-2; author reply 922 22586577 CMAJ. 2012 May 15;184(8):921; author reply 922 22586576 CMAJ. 2012 Feb 21;184(3):325 22354341 CMAJ. 2011 Nov 22;183(17):1957-8 22106102 CMAJ. 2011 Dec 13;183(18):2147 Adult Age Factors Aged BreastNeoplasms diagnosis mortality Canada Female Humans Magnetic Resonance Imaging Mammography Mass Screening Middle Aged Predictive Value of Tests Risk Factors PMC3225421 2011 11 23 6 0 2011 11 23 6 0 2012 1 20 6 0 ppublish
Detection of breastcancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breastcancer risk. 22474203 2012 04 04 2012 04 05 2016 12 15 1538-3598 307 13 2012 Apr 04 JAMA JAMA Detection of breastcancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breastcancer risk. 1394-404 10.1001/jama.2012.388 Annual ultrasound screening may detect small, node-negative breastcancers (...) that are not seen on mammography. Magnetic resonance imaging (MRI) may reveal additional breastcancers missed by both mammography and ultrasound screening. To determine supplemental cancer detection yield of ultrasound and MRI in women at elevated risk for breastcancer. From April 2004-February 2006, 2809 women at 21 sites with elevated cancer risk and dense breasts consented to 3 annual independent screens with mammography and ultrasound in randomized order. After 3 rounds of both screenings, 612 of 703
Possible net harms of breastcancerscreening: updated modelling of Forrest report. OBJECTIVE: To assess the claim in a Cochrane review that mammographic breastcancerscreening could be doing more harm than good by updating the analysis in the Forrest report, which led to screening in the United Kingdom. DESIGN: Development of a life table model, which replicated Forrest's results before updating and extending them with data from relevant systematic reviews, trials, and other models based (...) on purposive literature searches. PARTICIPANTS: Women aged 50 and over invited for breastcancerscreening. MAIN OUTCOME MEASURES: Quality adjusted life years (QALYs), combining life years gained from screening with losses of quality of life from false positive diagnoses and surgery. RESULTS: Inclusion of the effects of harms reduced the updated estimate of net cumulative QALYs gained after 20 years from 3301 to 1536 or by more than half. The best estimates from the Cochrane review generated negative QALYs
Effect of mammography screening on surgical treatment for breastcancer in Norway: comparative analysis of cancer registry data. OBJECTIVE: To determine the effect of mammography screening on surgical treatment for breastcancer. DESIGN: Comparative analysis of data from Norwegian cancer registry. SETTING: Mammography screening, Norway (screening of women aged 50-69 was introduced sequentially from 1996 to 2004). PARTICIPANTS: 35,408 women aged 40-79 with invasive breastcancer or ductal (...) carcinoma in situ treated surgically from 1993 to 2008. MAIN OUTCOME MEASURES: Rates of breast surgery (mastectomy plus breast conserving treatment) and rates of mastectomy for three age groups of women: 40-49, 50-69, and 70-79. Changes in rates from pre-screening period (1993-5) to introduction of screening phase (1996-2004) and then to screening period (2005-8) are presented as hazard ratios in invited and non-invited women. RESULTS: The annual rate for breast surgery from the pre-screening period
Breastcancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality database. OBJECTIVE: To compare trends in breastcancer mortality within three pairs of neighbouring European countries in relation to implementation of screening. DESIGN: Retrospective trend analysis. SETTING: Three country pairs (Northern Ireland (United Kingdom) v Republic of Ireland, the Netherlands v Belgium and Flanders (Belgian (...) region south of the Netherlands), and Sweden v Norway). DATA SOURCES: WHO mortality database on cause of death and data sources on mammography screening, cancer treatment, and risk factors for breastcancer mortality. MAIN OUTCOME MEASURES: Changes in breastcancer mortality calculated from linear regressions of log transformed, age adjusted death rates. Joinpoint analysis was used to identify the year when trends in mortality for all ages began to change. RESULTS: From 1989 to 2006, deaths from
Full-field digital mammography for breastcancerscreening Full-field digital mammography for breastcancerscreening Full-field digital mammography for breastcancerscreening Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Full-field digital mammography for breastcancerscreening. Lansdale: HAYES, Inc.. Directory Publication. 2011 Authors' objectives Full (...) -field digital mammography (FFDM) is an alternative to conventional screen-film mammography (SFM), the standard of care for detecting breastcancer. With digital mammography, images of the breast are acquired, displayed, transferred, and stored as digital data for viewing on a computer monitor (soft-copy reading) or for printing and viewing with a light box (hard-copy reading). In contrast to SFM, FFDM simplifies image interpretation because image acquisition, image processing, image review, and data
Accuracy and outcomes of screening mammography in women with a personal history of early-stage breastcancer. CONTEXT: Women with a personal history of breastcancer (PHBC) are at risk of developing another breastcancer and are recommended for screening mammography. Few high-quality data exist on screening performance in PHBC women. OBJECTIVE: To examine the accuracy and outcomes of mammography screening in PHBC women relative to screening of similar women without PHBC. DESIGN AND SETTING (...) : Cohort of PHBC women, mammogram matched to non-PHBC women, screened through facilities (1996-2007) affiliated with the BreastCancer Surveillance Consortium. PARTICIPANTS: There were 58,870 screening mammograms in 19,078 women with a history of early-stage (in situ or stage I-II invasive) breastcancer and 58,870 matched (breast density, age group, mammography year, and registry) screening mammograms in 55,315 non-PHBC women. MAIN OUTCOME MEASURES: Mammography accuracy based on final assessment
Organizational change: a way to increase colon, breast and cervical cancerscreening in primary care practices Organizational change: a way to increase colon, breast and cervical cancerscreening in primary care practices Organizational change: a way to increase colon, breast and cervical cancerscreening in primary care practices Arroyave AM, Penaranda EK, Lewis CL CRD summary Organisational change interventions that circumvented the physician were most effective in increasing cancerscreening (...) published in English between January 1990 and July 2010. Search terms were reported. References of relevant studies were handsearched for further studies. Study selection Eligible randomised controlled trials (RCTs) that reported the impact of organisational change interventions implemented by practice staff on colorectal, breast or cervical cancerscreening rates. Eligible outcomes were test completion of flexible sigmoidoscopy, colonoscopy, faecal occult blood test, mammography, clinical breast
Effectiveness of mammography screening in reducing breastcancer mortality in women aged 39-49 years: a meta-analysis Effectiveness of mammography screening in reducing breastcancer mortality in women aged 39-49 years: a meta-analysis Effectiveness of mammography screening in reducing breastcancer mortality in women aged 39-49 years: a meta-analysis Magnus MC, Ping M, Shen MM, Bourgeois J, Magnus JH CRD summary This review concluded that mammography screenings were effective and reduced (...) breastcancer mortality in women aged 39 to 49 by 17%. This represented a reduction from a very low absolute risk; the authors further concluded that women should be clearly informed of both positive and negative aspects of screening. The conclusion as a whole is likely to be reliable. Authors' objectives To evaluate the effectiveness of mammography screening in women aged 39 to 49 years for the reduction of breastcancer mortality. Searching MEDLINE, The Cochrane Library and ERIC were searched up
Screening Mammography for Women Aged 40 to 49 Years at Average Risk for BreastCancer 1 OHTAC Recommendation Screening Mammography for Women Aged 40 to 49 Years at Average Risk for BreastCancer Updated January 2011 This recommendation summary has been prepared by the Medical Advisory Secretariat of the Ministry of Health and Long Term Care on behalf of the Ontario Health Technology Advisory Committee. Presented to the Ontario Health Technology Advisory Committee in November, 2010 Issue (...) Background Breastcancer is a disease of aging with a four-fold higher incidence in women 50 to 69 years of age (500 per 100,000 women) compared to women 40 to 49 years of age (140 per 100,000 women). The estimated number of new breastcancer diagnoses in Ontario women 40 to 49 year of age is approximately 1,400 per year. There are approximately 1.02 million women in this age group in Ontario at present. The MAS review assessed the effectiveness of screening (film) mammography in women 40 to 49 years
The Efficacy of Breast Specific Gamma Imaging Over Mammography for BreastCancerScreening in All Women. "The Efficacy of Breast Specific Gamma Imaging Over Mammography for Bre" by Tawny Schmeer < > > > > > Title Author Date of Award Winter 1-2011 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Dr. Torry Cobb Rights . Abstract Background: As the second most diagnosed cancer among women in the US, breastcancer has been, and continues (...) to be, a life threatening disease affecting thousands. Mammography has been the primary tool used in screening for breastcancer for decades, despite minimal advancement in the area of its main limitation, dense breast tissue. Recently gamma imaging has undergone significant improvements in the area of breast specific imaging and appears primed to address the needs of a population where mammography is insufficient. The purpose of this systematic review is to compare the efficacy of Breast Specific Gamma
Effect of screening mammography on breast-cancer mortality in Norway. BACKGROUND: A challenge in quantifying the effect of screening mammography on breast-cancer mortality is to provide valid comparison groups. The use of historical control subjects does not take into account chronologic trends associated with advances in breast-cancer awareness and treatment. METHODS: The Norwegian breast-cancerscreening program was started in 1996 and expanded geographically during the subsequent 9 years (...) . Women between the ages of 50 and 69 years were offered screening mammography every 2 years. We compared the incidence-based rates of death from breastcancer in four groups: two groups of women who from 1996 through 2005 were living in counties with screening (screening group) or without screening (nonscreening group); and two historical-comparison groups that from 1986 through 1995 mirrored the current groups. RESULTS: We analyzed data from 40,075 women with breastcancer. The rate of death
Revisiting the USPSTF BreastCancerScreening Guidelines: Ethics, and Patient Responsibilities Revisiting the USPSTF BreastCancerScreening Guidelines: Ethics, and Patient Responsibilities | Clinical Correlations Revisiting the USPSTF BreastCancerScreening Guidelines: Ethics, and Patient Responsibilities May 6, 2010 David Shabtai Faculty Peer Reviewed In a bold move, the U.S. Preventive Services Task Force recently changed their breastcancerscreening guidelines – recommending beginning (...) or older.” Focusing on the younger group, the report clarifies that it applies only to women of average risk. While the previous 2002 USPSTF recommendations encouraged screening mammography for women aged 40-49, new evidence has prompted the recent shift. Pooled meta-analysis showed that the risk reduction for breastcancer mortality in women aged 39-49 and 50-59 was almost identical, at 0.85 and 0.86 respectively. However, because of the lower incidence of breastcancer in the younger women, 1904
Breastcancer mortality in organised mammography screening in Denmark: comparative study. OBJECTIVE: To determine whether the previously observed 25% reduction in breastcancer mortality in Copenhagen following the introduction of mammography screening was indeed due to screening, by using an additional screening region and five years additional follow-up. DESIGN: We used Poisson regression analyses adjusted for changes in age distribution to compare the annual percentage change in breast (...) in the Cause of Death Register and Statistics Denmark for 1971-2006. MAIN OUTCOME MEASURE: Annual percentage change in breastcancer mortality in regions offering mammography screening and those not offering screening. RESULTS: In women who could benefit from screening (ages 55-74 years), we found a mortality decline of 1% per year in the screening areas (relative risk (RR) 0.99, 95% confidence interval (CI) 0.96 to 1.01) during the 10 year period when screening could have had an effect (1997-2006
Interventions to promote repeat breastcancerscreening with mammography: a systematic review and meta-analysis Interventions to promote repeat breastcancerscreening with mammography: a systematic review and meta-analysis Interventions to promote repeat breastcancerscreening with mammography: a systematic review and meta-analysis Vernon SW, McQueen A, Tiro JA, del Junco DJ CRD summary Reminder-only interventions and more intensive strategies of education/motivation or counselling (...) significantly promoted repeat mammography screening for breastcancer. The high level of heterogeneity found for reminder-only studies precluded the conclusion that they were more effective than alternative strategies. Potential limitations to the review process and uncertain study quality make the reliability of the authors’ conclusions unclear. Authors' objectives To evaluate the efficacy of interventions, particularly reminder-only interventions, to promote repeat breastcancerscreening with mammography
A rapid-response economic evaluation of the UK NHS Cancer Reform Strategy breastcancerscreening program extension via a plausible bounds approach A rapid-response economic evaluation of the UK NHS Cancer Reform Strategy breastcancerscreening program extension via a plausible bounds approach A rapid-response economic evaluation of the UK NHS Cancer Reform Strategy breastcancerscreening program extension via a plausible bounds approach Madan J, Rawdin A, Stevenson M, Tappenden P Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The aim was to estimate the cost-effectiveness of a breastcancerscreening programme for women aged 47 to 49 years and to determine the key factors affecting this estimate. The authors concluded