Latest & greatest articles for babies

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Top results for babies

1. Support during pregnancy for women at increased risk of low birthweight babies. (PubMed)

Support during pregnancy for women at increased risk of low birthweight babies. Studies consistently show a relationship between social disadvantage and low birthweight. Many countries have programmes offering special assistance to women thought to be at risk for giving birth to a low birthweight infant. These programmes, collectively referred to in this review as additional social support, may include emotional support, which gives a person a feeling of being loved and cared for, tangible (...) , instrumental/tangible and informational) compared with routine care, for pregnant women believed to be at high risk for giving birth to babies that are either preterm (less than 37 weeks' gestation) or weigh less than 2500 g, or both, at birth. Secondary objectives were to determine whether the effectiveness of support was mediated by timing of onset (early versus later in pregnancy) or type of provider (healthcare professional or lay person).For this update, we searched Cochrane Pregnancy and Childbirth's

2019 Cochrane

2. Specialist neonatal respiratory care for babies born preterm

Specialist neonatal respiratory care for babies born preterm Specialist neonatal respir Specialist neonatal respiratory care for atory care for babies born preterm babies born preterm NICE guideline Published: 3 April 2019 nice.org.uk/guidance/ng124 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived (...) be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Specialist neonatal respiratory care for babies born preterm (NG124) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

3. Oral ibuprofen may be an option for closing patent ductus arteriosus in premature babies

Oral ibuprofen may be an option for closing patent ductus arteriosus in premature babies Oral ibuprofen may be an option for closing patent ductus arteriosus in premature babies Discover Portal Discover Portal Oral ibuprofen may be an option for closing patent ductus arteriosus in premature babies Published on 3 July 2018 doi: A high dose of oral ibuprofen was more likely to close a patent ductus arteriosus in premature babies when compared with standard doses of intravenous ibuprofen (...) or indometacin. Before birth, a baby's lungs aren't needed for breathing. Most blood bypasses the lungs through a large vessel called the ductus arteriosus directly from the pulmonary artery into the aorta to supply the main circulation. Once born, blood flows through the lungs, and the ductus arteriosus usually closes in the first few days. If it doesn't close it is referred to as "patent". This condition is much more common in premature babies and doesn't always need treatment, but if causing problems may

2019 NIHR Dissemination Centre

4. Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously

Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Discover Portal Discover Portal Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Published on 12 December 2017 doi: Pregnant women with type 1 diabetes who used a continuous glucose monitoring system were half (...) as likely to have a large baby compared with those using standard finger prick blood glucose measurements. Only 15% of infants needed intensive care admissions due to low blood glucose in the continuous glucose monitoring group, compared with 28% born to mothers in the standard finger prick control group. Pregnant women using continuous monitoring spent 7% more time in the target glucose range than those on standard measurements. However, their HbA1c levels, which indicate diabetic control over 12 weeks

2019 NIHR Dissemination Centre

5. Placing wet gauze on babies’ tummies speeds up urine collection

Placing wet gauze on babies’ tummies speeds up urine collection Placing wet gauze on babies’ tummies speeds up urine collection Discover Portal Discover Portal Placing wet gauze on babies’ tummies speeds up urine collection Published on 17 October 2017 doi: Almost a third of infants managed to urinate within five minutes after a painless, cheap technique that stimulates the skin, compared with 12% of infants observed only, as is standard practice. The ‘Quick-Wee’ method involved rubbing (...) the babies’ abdomens gently with gauze soaked in cold saline before collecting urine. This trial was carried out with 354 babies aged one to 11 months in one Australian paediatrics emergency room. NICE guidelines recommend non-invasive ‘clean catch’ collection if possible but this can be difficult, especially in young children. They estimate that 20 minutes of staff time can be needed to obtain a sample. Hospital paediatrics settings and primary care may want to try this promising, cheap and safe

2019 NIHR Dissemination Centre

6. Induction of labour may be considered in pregnant women with a large baby

Induction of labour may be considered in pregnant women with a large baby Induction of labour may be considered in pregnant women with a large baby Discover Portal Discover Portal Induction of labour may be considered in pregnant women with a large baby Published on 20 June 2017 doi: Induction of labour does not increase the risk of caesarean delivery in pregnant women with a larger than average baby. This is based on a review of four trials of 1190 women with a suspected large baby who were (...) allocated either to have labour induced from 38 weeks or to watchful waiting. Induction did not increase the risk of most negative outcomes for the baby, such as bleeding in the brain, or mother, such as major tearing. However, these outcomes are rare, so a larger number of women would need to be studied to be confident in these findings. When mothers were not induced babies were larger and born about a week later than if they were induced. They did suffer from more fractures, which can

2019 NIHR Dissemination Centre

7. Assisted reproduction using donated eggs has higher risk of complications for mothers and babies

Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Discover Portal Discover Portal Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Published on 13 December 2016 doi: Assisted reproduction with donated eggs carries about double the chance of some risks for mothers and babies when compared to pregnancies (...) involving donated eggs was in 1984. Since then, several studies have reported that high blood pressure during pregnancy, including pre-eclampsia, is more common in women who receive IVF using donor eggs. Pre-eclampsia is a major cause of maternal illness and mortality. Other studies have suggested that babies of egg donation pregnancies may also have poorer outcomes. This systematic review aimed to pool the results of these observational studies, to get a clearer picture of the potential risks

2019 NIHR Dissemination Centre

8. Antenatal corticosteroids reduce breathing problems in late preterm babies

Antenatal corticosteroids reduce breathing problems in late preterm babies Antenatal corticosteroids reduce breathing problems in late preterm babies Discover Portal Discover Portal Antenatal corticosteroids reduce breathing problems in late preterm babies Published on 21 February 2017 doi: Giving corticosteroids to women at risk of preterm birth at 34 weeks of pregnancy or later reduced the risk of severe breathing problems in the baby after birth from 1.9% to 1.1%. Steroids also reduced (...) the risk for babies born by planned caesarean section after 37 weeks (so not premature). Steroids are known to be beneficial if given to pregnant women at risk of preterm birth before 34 weeks and are already advised for babies born by caesarean section. This meta-analysis of six large trials provides new evidence that steroids might also benefit premature babies born after the 34th week. However, the review also found steroids increased the risk of low blood sugar in the new-born, which would need

2019 NIHR Dissemination Centre

9. Breastfeeding reduces crying during baby immunisation

Breastfeeding reduces crying during baby immunisation Breastfeeding reduces crying during baby immunisation Discover Portal Discover Portal Breastfeeding reduces crying during baby immunisation Published on 21 February 2017 doi: Babies who were breastfed before and during routine childhood immunisations cried on average for 38 seconds less and had lower pain scores compared to babies not breastfed. This evidence review used data from 10 trials, with results for 1,066 babies, mostly between one (...) and six months old, following their normal immunisation schedule. Immunisation levels in England are below recommended levels and falling. Pain from injections causes distress to babies and parents, and may put parents off bringing their children for immunisation or finishing the course of treatment over a year. This is the first review to focus studies of breastfeeding for any painful procedure for older babies. The only trials found related to immunisations, and none was on other procedures

2019 NIHR Dissemination Centre

10. Skin-to-skin contact improves breastfeeding of healthy babies

Skin-to-skin contact improves breastfeeding of healthy babies Skin-to-skin contact improves breastfeeding of healthy babies Discover Portal Discover Portal Skin-to-skin contact improves breastfeeding of healthy babies Published on 28 March 2017 doi: Early skin-to-skin contact improves breastfeeding of healthy full-term babies. Skin-to-skin contact is the direct contact between a naked baby and the mother’s bare chest. It can occur before or after the baby is cleaned following birth. This review (...) found that about a quarter more women who have this contact with their babies are still breastfeeding at one to four months after birth compared with those who don’t. The evidence that skin-to-skin contact may also help to stabilise the baby’s heart and breathing rates and blood sugar levels after birth was based on fewer trials and less strong. These findings support UK good practice to promote immediate skin-to-skin contact after birth to improve breastfeeding rates. It remains one

2019 NIHR Dissemination Centre

11. Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk

Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Discover Portal Discover Portal Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Published on 18 April 2017 doi: Providing very-low-birthweight babies with fortified human donor breast milk made (...) no difference to their developmental neurological outcomes at 18 months compared with giving formula. This randomised controlled trial looked at 363 babies with birth weights of less than 1500g in neonatal intensive care units in Canada. When the mother’s own milk supply was limited, the babies were given either nutrient-enriched donor breast milk or formula developed for premature babies. There was no difference in their understanding, language, or ability to manipulate objects at 18 months. This finding

2019 NIHR Dissemination Centre

12. Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success

Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Discover Portal Discover Portal Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Published on 13 December 2016 doi: For women who chose to breastfeed their preterm baby, supplementary feeds with a cup, compared with a bottle, led to improved breastfeeding rates (...) at discharge and up to six months later. Preterm babies who are transitioning from being tube fed to breastfeeds have traditionally been given bottle feeds (of breast milk or formula) to supplement breastfeeding if the mother is unavailable or if additional feeds are thought necessary. This small Cochrane review found evidence that babies were more likely to be fully breastfed or to have at least some breastfeeds when cup feeds were used to supplement breastfeeding. In contrast to a 2008 review on the same

2019 NIHR Dissemination Centre

13. Inducing labour in older women having their first baby does not increase the chance of caesarean delivery

Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Discover Portal Discover Portal Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Published on 26 April 2016 doi: Planning to artificially start labour for older women, pregnant with their first child, in the 39th week of pregnancy (...) does not affect the chance of having a caesarean delivery, according to a new trial funded by NIHR. Older women having a first baby have a higher risk of stillbirth and other complications than younger mothers and inducing labour at or before the due date is thought to reduce this risk. However, there have been fears that inducing labour may raise the risk of a caesarean delivery. This study found that women aged 35 or over having their first child and who were induced at 39 weeks had no higher

2019 NIHR Dissemination Centre

14. High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies

High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies Discover Portal Discover Portal High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies Published on 17 May 2016 doi: This systematic review found high-flow oxygen delivered by nose was as effective and safe as other non-invasive (...) methods of breathing support for preterm babies. The numbers of treatment failures, deaths and rates of chronic lung disease were similar. Most studies were of high-flow oxygen for babies after tubes used for ventilation had been removed. For these babies use of high-flow techniques were less likely to cause nasal damage or a collapsed lung than other non-invasive methods. High-flow oxygen therapy delivers gas through thin tubes that sit just inside each nostril, whereas the most common non-invasive

2019 NIHR Dissemination Centre

15. Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother’s lifestyle

Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother’s lifestyle Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother’s lifestyle Discover Portal Discover Portal Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother’s lifestyle Published on 6 June 2016 doi: This NIHR funded study found that antipsychotic use during pregnancy was not associated with worse

2019 NIHR Dissemination Centre

16. Preterm babies do not benefit from a new IV feeding regimen

Preterm babies do not benefit from a new IV feeding regimen Preterm babies do not benefit from a new IV feeding regimen Discover Portal Discover Portal Preterm babies do not benefit from a new IV feeding regimen Published on 14 July 2016 doi: Intravenous feeding solutions with a higher dose of amino acids or solutions containing fish oils do not provide better outcomes for preterm infants. Many preterm babies can’t feed normally for the first few weeks after birth so they are given a mixture (...) acids or emulsions containing fish oils are beneficial compared to a standard approach, where the dose of amino acids is slowly increased and soya oil is used. Share your views on the research. Why was this study needed? Each year about 8000 extremely preterm infants, born before 31 weeks of gestation, are born in the UK. Until they are able to tolerate milk feeds most of these babies receive intravenous feeding which starts at a variable time after birth and is usually increased slowly, though

2019 NIHR Dissemination Centre

17. Testing oxygen levels of newborn babies helps find serious heart defects

Testing oxygen levels of newborn babies helps find serious heart defects Testing oxygen levels of newborn babies helps find serious heart defects Discover Portal Discover Portal Testing oxygen levels of newborn babies helps find serious heart defects Published on 17 July 2018 doi: Measuring oxygen levels in newborn babies as part of routine care can identify cases of critical congenital heart defects sooner than waiting until symptoms appear. If 10,000 babies were screened, pulse oximetry could (...) correctly identify about 5 of the 6 expected asymptomatic cases and might miss one. This international research suggests there would be about 14 false alarms. Waiting until babies are at least 24 hours old minimises the number of these false positives. Babies with critical heart defects often show no symptoms at birth. Early detection of these problems increases the chance of successful treatment. This systematic review looked at 21 studies of 457,202 babies where pulse oximetry (measuring the amount

2019 NIHR Dissemination Centre

18. Domperidone increases breast milk production in mothers of premature babies

Domperidone increases breast milk production in mothers of premature babies Domperidone increases breast milk in mothers of premature babies Discover Portal Discover Portal Domperidone increases breast milk production in mothers of premature babies Published on 8 May 2018 doi: The drug domperidone increases the amount of breast milk women produce. This review looked at its use for up to two weeks in women with premature babies being fed with expressed milk. Women had a moderate increase (...) in breast milk of about 88ml a day, a clinically important increase for these small babies. Domperidone is an anti-sickness medication. It has not been widely used to increase breast milk because of unknown effectiveness and concerns that it can cause an irregular heart rhythm with longer-term use in older people. This review found it can moderately increase milk production. Though no serious or cardiac side effects occurred in the studies, only 192 women participated in the trials, so rarer side

2019 NIHR Dissemination Centre

19. Premature babies have fewer complications if a lower platelet count is accepted

Premature babies have fewer complications if a lower platelet count is accepted Premature babies have fewer complications if a lower platelet count is accepted Discover Portal Discover Portal Premature babies have fewer complications if a lower platelet count is accepted Published on 22 January 2019 doi: Fewer premature babies die or have major bleeding if platelet transfusions are withheld until platelet numbers drop to a lower level. At 28 days, death or new major bleeding occurred in 19 (...) % of neonates transfused when they had less than 25,000/mm 3 platelets compared to 26% of neonates transfused when they had less than 50,000/mm 3 platelets. This trial included 660 premature babies with low platelet counts. The results suggest that in the absence of actual bleeding, platelet transfusions may be safer to give when blood platelet concentrations are lower than currently recommended trigger thresholds. It remains unclear why there was an increased risk of the combined outcome of either death

2019 NIHR Dissemination Centre

20. A new method for monitoring baby’s heart beat during labour probably not justified

A new method for monitoring baby’s heart beat during labour probably not justified A new method for monitoring baby’s heart beat during labour probably not justified Discover Portal Discover Portal A new method for monitoring baby’s heart beat during labour probably not justified Published on 1 March 2016 doi: A new way of monitoring a baby’s distress during labour, called ST waveform analysis, did not improve outcomes for the baby or reduce the likelihood of a caesarean section compared (...) to current practice. Although monitoring of babies’ heartbeats during labour is common practice in the UK, additional ST analysis is not commonly used and on the basis of this evidence probably should not be promoted for routine use yet. The outcomes measured in this review included death of the baby before or after birth, fits and brain damage from low oxygen levels. Finding babies at risk of these rare events is important as urgent delivery may save the baby. However if there is a role for ST analysis

2019 NIHR Dissemination Centre