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Latest & greatest articles for azithromycin
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Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 7629982 1995 09 06 1995 09 06 2016 10 17 0098-7484 274 7 1995 Aug 16 JAMA JAMA Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 545-9 To evaluate the use of single-dose azithromycin for empirical treatment of nongonococcal urethritis. Randomized, double-blind, multicenter trial comparing azithromycin vs (...) doxycycline therapy, with a 2:1 randomization ratio. Patients were evaluated clinically and microbiologically for Chlamydia trachomatis and Ureaplasma urealyticum infection before therapy and at 2 and 5 weeks after study entry. Eleven sexually transmitted disease clinics throughout the United States. A total of 452 men aged 18 years or older with symptomatic nongonococcal urethritis of less than 14 days' duration. Patients were treated with either 1.0 g of azithromycin as a single oral dose or 100 mg
Effects of azithromycin on malariometric indices in The Gambia. 7564674 1995 10 27 1995 10 27 2015 06 16 0140-6736 346 8979 1995 Sep 30 Lancet (London, England) Lancet Effects of azithromycin on malariometric indices in The Gambia. 881-2 Azithromycin (a macrolide-like antibiotic) has antimalarial effects in vitro and in animal models. In the course of a randomised trial of trachoma control we examined the effects of azithromycin on parasite and spleen rates in the population aged 5-14 years (...) from eight villages in the Farafenni study area in The Gambia, West Africa. The entire population of four treatment villages received three doses of azithromycin 20 mg/kg weekly (days 1, 8, and 15) and four control villages received daily tetracycline eye ointment topically (days 1-42). Among 226 children studied before treatment and at day 28, azithromycin reduced the proportions with Plasmodium falciparum parasites (rate ratio 0.56, 95% confidence interval 0.44-0.71; p < 0.0001), with palpable
Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 8102427 1993 09 13 1993 09 13 2015 06 16 0140-6736 342 8869 1993 Aug 21 Lancet (London, England) Lancet Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 453-6 Blindness due to trachoma is a serious public health issue world wide. The currently recommended treatment of active trachoma with repeated doses of tetracycline eye ointment has many disadvantages. The new azalide antibiotic (...) azithromycin is effective as a single oral dose in the chemotherapy of genital Chlamydia trachomatis infections, and we have assessed its efficacy for trachoma treatment. We carried out a randomised single-blind comparison of azithromycin (a single oral dose of 20 mg/kg) with conventional treatment (6 weeks of topical tetracycline plus erythromycin for severe cases) in two villages with endemic trachoma in The Gambia. The patients were followed up for 26 weeks from the start of treatment by an observer
A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. 1325036 1992 09 30 1992 09 30 2013 11 21 0028-4793 327 13 1992 Sep 24 The New England journal of medicine N. Engl. J. Med. A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. 921-5 Currently, there is no single-dose (...) therapy that is effective in the treatment of urethral or endocervical infections with Chlamydia trachomatis. Azithromycin is a new azalide antibiotic that has substantial activity against C. trachomatis, is concentrated intracellularly, and has a long half-life in serum and tissue. We conducted a trial in which 299 female patients and 158 male patients with uncomplicated genital infection and a positive C. trachomatis antigen test were randomly assigned to receive either azithromycin (1 g once orally