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Latest & greatest articles for autism
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.
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Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.
Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.
Autism causes and treatment
There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.
The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.
Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.
Hot topics in Trip
Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.
Treatment for Insomnia and Disrupted Sleep Behavior in Children and Adolescents with Autism Spectrum Disorder 1 1 Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and 2 adolescents with autism spectrum disorder 3 4 Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the 5 American Academy of Neurology 6 7 Ashura Williams Buckley, MD, 1 Deborah Hirtz, MD, 2 Maryam Oskoui, MD, 3 Melissa J. 8 Armstrong, MD, MSc, 4 Anshu Batra (...) . Division of Developmental Medicine, Boston Children’s Hospital, Boston, MA 24 2 7. Departments of Pediatrics and Psychiatry, The Ohio State University College of 1 Medicine, Columbus 2 8. Duke Center for Autism and Brain Development, Duke Institute for Brain Sciences, and 3 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 4 Durham, NC 5 9. Northern Michigan Neurology, Traverse City 6 10. Department of Child and Behavioral Sciences, Johns Hopkins University
, diagnosed with ASD (inclusive of autism, ASD, Autistic Disorder, Asperger's Disorder, Asperger Syndrome, atypical autism, PDD‐NOS) by a professional eligible to diagnose these conditions, and also experiencing anxiety symptoms or a diagnosis of an anxiety disorder provided by a professional eligible to diagnose such conditions. The majority of included studies (21 of 24) used a screening instrument to confirm the existence of clinically significant levels of anxiety at intake, while the remaining (...) excluded at abstract screening stage Author and Publication Date Title Reason for exclusion Schohl et al. ( ) A replication and extension of the PEERS intervention: Examining effects on social skills and social anxiety in adolescents with autism spectrum disorders. Different intervention focus, no anxiety diagnosis or measurement at intake Ooi et al. ( ) Effects of cognitive‐behavioral therapy on anxiety for children with high‐functioning autistic spectrum disorders. Observational study (pre‐post
, O'Reilly M, Healy O, Rispoli M, Lydon H, Streusand W, Davis T, Kang S, Sigafoos J, Lancioni G, Didden R, Giesbers S. Sensory integration therapy for autism spectrum disorders: a systematic review. Research in Autism Spectrum Disorders 2012; 6(3): 1004-1018 DOI Original Paper URL Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder; Child; Humans; Occupational Therapy; Sensation; Sensation Disorders AccessionNumber 12012026826 Date bibliographic record published 29/08/2012 Date (...) Sensory integration therapy for autism spectrum disorders: a systematic review Sensory integration therapy for autism spectrum disorders: a systematic review Sensory integration therapy for autism spectrum disorders: a systematic review Lang R, O'Reilly M, Healy O, Rispoli M, Lydon H, Streusand W, Davis T, Kang S, Sigafoos J, Lancioni G, Didden R, Giesbers S CRD summary The authors concluded that sensory integration therapy had no consistently positive effect as a treatment for children
included studies. Randomized Controlled Trials Schaaf, 2014 2 Children (4-8 y) with autism (n = 32) Occupational therapy (manualized intervention) Improved Goal Attainment Scale scores, measures of caregiver assistance in self-care, and socialization compared with usual care. Chan, 2013 3 Children with ASD (n = 46) Nei Yang Gong Larger self-control improvements occurred in the treatment group compared with a Progressive Muscle Relaxation technique control group, parental reports of reduced autistic (...) symptoms. Pfeiffer, 2011 4 Children (6-12 y) with ASD Sensory integration The intervention successfully reduced autistic mannerisms compared with fine motor intervention. Both groups showed improved Goal Attainment Scaling scores. Silva, 2011 5 Children with Qigong massage Improved measures of autism, Motor Interventions for Autism Spectrum Disorder in Children 2 autism (n = 47) abnormal sensory responses, and self-regulation were reported in the treatment group. Piravej, 2009 6 Children (3-10 y
. 23672 6. 1 OR 2 OR 3 OR 4 OR 5 40896 7. "Autistic Disorder"/ or "Autism Spectrum Disorder"/ 26189 8. (Autism or Autistic* or "ASD" or "Autism spectrum disorder*").ti,ab,kw. 50587 9. 7 OR 8 53333 10. 6 OR 9 90701 Intervention: 11. Exercise/ 101551 12. ("Physical" adj6 ("Activit*" or "therap*" or "exercise" or “training”)).ti,ab,kw. 155219 13. (exercise* or physiotherapy or sport*).ti,ab. 345492 14. 11 OR 12 OR 13 466786 Limits: 15. (((comprehensive* or integrative or systematic*) adj3 (bibliographic (...) found Population: 1. [mh “Attention Deficit and Disruptive Behavior Disorders”] 2809 2. [mh “Attention Deficit Disorder with Hyperactivity”] 2482 3. (“Attention Deficit Disorder*”:ab,ti) 3751 4. ("Attention deficit*":ab,ti NEAR hyper*:ab,ti) 3529 5. (“adhd”:ti,ab,kw OR “addh”:ti,ab) 4168 6. 1 OR 2 OR 3 OR 4 OR 5 5506 7. [mh "Autistic Disorder"] 867 8. [mh "Autism Spectrum Disorder"] 1211 9. ("Autism" or Autist* or "ASD" OR "Autism spectrum*"):ti,ab 3467 10. 7 OR 8 OR 9 3523 11. 6 OR 10 8787
Early detection for autism spectrum disorder in young children Autism spectrum disorder (ASD) is a life-long neurodevelopmental disorder, characterized by impairments in social communication, repetitive, restricted patterns of behaviour, and unusual sensory sensitivities or interests. ASD significantly impacts the lives of children and their families. Currently, the estimated prevalence of ASD is 1 in 66 Canadians aged 5 to 17 years. General paediatricians, family physicians, and other health (...) signs of ASD—an important step toward an accurate diagnosis and comprehensive needs assessment for intervention planning. Keywords: Autism spectrum disorder; Developmental surveillance; Early identification; Screening
Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Berry A, Borgi M, Francia N, Alleva E, Cirulli F CRD summary This poorly reported review concluded that studies were encouraging (...) and indicated therapy or assistance dogs could promote positive behaviours in children diagnosed with autism spectrum disorders, but called for further research. The results cannot be considered reliable given the apparent variability in the small evidence base. Authors' objectives To provide a critical review of the literature assessing the effects of therapy and assistance dogs on children with autism spectrum disorders and their families. Searching PubMed, ERIC, Science Direct, Google Scholar, reference
acquired acquired language skills (regression). Rogers SJ. Developmental regression in autistic spectrum disorders. Ment Retard Dev Disabil Res Rev. 2004;10(2):139-43. http://www.ncbi.nlm.nih.gov/pubmed/15362172?tool=bestpractice.com Parr JR, Le Couteur A, Baird G, et al. Early developmental regression in autism spectrum disorder: evidence from an international multiplex sample. J Autism Dev Disord. 2011 Mar;41(3):332-40. http://www.ncbi.nlm.nih.gov/pubmed/20711649?tool=bestpractice.com Children who (...) Autism spectrum disorder Autism spectrum disorder - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Autism spectrum disorder Last reviewed: February 2019 Last updated: March 2018 Summary Children and adults with autism spectrum disorder (ASD) have social communication and interaction difficulties and show restricted, repetitive, and stereotyped patterns of behaviours, interests, or activities. Social communication
research focused on interventions for adolescents and young adults between the ages of 13 and 30 with autism spectrum disorder (ASD; autistic disorder, Asperger’s syndrome, pervasive developmental disorder–not otherwise specified). We addressed questions related to: the effectiveness of therapies targeting core symptoms of ASD (impairments in communication, social interaction, and behavior); common medical or mental health comorbidities, including associated symptoms such as irritability; the process (...) Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Future Research Needs Paper Number 20 Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Future Research Needs Paper Number 20 Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Identification of Future Research Needs From Comparative Effectiveness Review No. 65 Prepared for: Agency for Healthcare
search covered the period from 1991 to March 19, 2013 using the PubMed, PsycINFO, Cochrane, and CINAHL (EBSCO) databases. The initial searches were inclusive and sensitive. Search terms were a combination of MeSH headings and keywords, and the MeSH headings were adjusted to terms used by PsycINFO and CINAHL by using their thesauri. In PubMed the MeSH terms autistic disorder, childhood development disorders—pervasive, Asperger*, and Rett* and the keyword autism were searched. The initial search (...) OF CHILD & ADOLESCENT PSYCHIATRY VOLUME 53 NUMBER 2 FEBRUARY 2014 www.jaacap.org 237andvalidationstudies.There?nedPubMedsearch yielded3,613articles. In the PsycINFO database subject headings (focused) of autism, autistic thinking, pervasive developmental disorders, retts syndrome, aspergers, and keyword autism were searched. The initial search returned 24,875 articles and was then limited to English, childhood: birth to age 12yrs, adolescence: age 13-17 yrs, peer reviewed journal,and 1991 to March 19
Melatonin (Slenyto) - Treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome 1 Published 9 September 2019 1 SMC2168 melatonin 1mg and 5mg prolonged-release tablets (Slenyto®) Flynn Pharma Ltd 9 August 2019 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. The advice is summarised (...) as follows: ADVICE: following a full submission melatonin prolonged-release (Slenyto ® ) is not recommended for use within NHSScotland. Indication under review: Treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient. Melatonin prolonged-release (Slenyto ® ), compared with placebo, increased total sleep time and sleep onset latency in children aged 2 to 17.5 years with sleep
Standards of diagnostic assessment for autism spectrum disorder The rising prevalence of autism spectrum disorder (ASD) has created a need to expand ASD diagnostic capacity by community-based paediatricians and other primary care providers. Although evidence suggests that some children can be definitively diagnosed by 2 years of age, many are not diagnosed until 4 to 5 years of age. Most clinical guidelines recommend multidisciplinary team involvement in the ASD diagnostic process. Although (...) on referral for a comprehensive needs assessment both for treatment and intervention planning, using a flexible, multilevel approach. Keywords: Autism spectrum disorder; Diagnostic evaluation; Intervention planning
. The inclusion of adults is in response to the increasing understanding that autism spectrum disorder (ASD) is a lifelong condition in which the core features of ASD persist whilst manifesting differently according to different age stages. Depending on the severity of autistic difficulties, ASD may not be evident as a presentation throughout preschool, primary, or secondary school years or in adulthood. It may not be recognised because of associated coexisting conditions. Variable environmental factors (...) on cognition. A study conducted in a gender clinic in London reported that among the 92 participants the prevalence of autistic traits, based on assessment with the Autism Spectrum Quotient (AQ) was 5.5% (3 male to female and 2 female to male transsexuals) compared to reports of clinical diagnoses of 0.5–2.0% in the general population. 49 Further indicators of possible ASD in adults are listed in Annex 2. Healthcare professionals should be aware of indicators for ASD in adults presenting with other
Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. The hypothesized link between the measles, mumps, rubella (MMR) vaccine and autism continues to cause concern and challenge vaccine uptake.To evaluate whether the MMR vaccine increases the risk for autism in children, subgroups of children, or time periods after vaccination.Nationwide cohort study.Denmark.657 461 children born in Denmark from 1999 through 31 December 2010, with follow-up from 1 year of age and through 31 (...) August 2013.Danish population registries were used to link information on MMR vaccination, autism diagnoses, other childhood vaccines, sibling history of autism, and autism risk factors to children in the cohort. Survival analysis of the time to autism diagnosis with Cox proportional hazards regression was used to estimate hazard ratios of autism according to MMR vaccination status, with adjustment for age, birth year, sex, other childhood vaccines, sibling history of autism, and autism risk factors
Autism Top results for autism - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading (...) history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for autism The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest
The Effect of Sensory Integration Therapy on Occupational Performance in Children With Autism. Sensory processing problems and related dysfunctions are among the most common conditions in children with autism spectrum disorder (ASD). This study examined the effect of sensory integration therapy (SIT) on different aspects of occupational performance in children with ASD. The study was conducted on an intervention group ( n = 16) receiving SIT and a control group ( n = 15) with 3- to 8-year-old