Latest & greatest articles for autism

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

161. [Efficacy, effectiveness and safety of behavioural interventions in patients with autism spectrum disorders]

[Efficacy, effectiveness and safety of behavioural interventions in patients with autism spectrum disorders] Efectividad de las terapias conductuales en los trastornos del espectro autista [Efficacy, effectiveness and safety of behavioural interventions in patients with autism spectrum disorders] Efectividad de las terapias conductuales en los trastornos del espectro autista [Efficacy, effectiveness and safety of behavioural interventions in patients with autism spectrum disorders] Reza-Goyanes (...) M Citation Reza-Goyanes M. Efectividad de las terapias conductuales en los trastornos del espectro autista. [Efficacy, effectiveness and safety of behavioural interventions in patients with autism spectrum disorders] Unidad de Evaluacion de Tecnologias Sanitarias (UETS). UETS 2011/05. 2012 Authors' conclusions Studies show benefits achieved with some behavioural interventions. But these results must be interpreted with caution because of the absence of results consistency between studies

2012 Health Technology Assessment (HTA) Database.

162. Some childhood autistic traits are associated with psychotic experiences in early adolescence

Some childhood autistic traits are associated with psychotic experiences in early adolescence Some childhood autistic traits are associated with psychotic experiences in early adolescence | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Some childhood autistic traits are associated with psychotic experiences in early adolescence Article Text Prognosis Some childhood autistic traits are associated with psychotic experiences in early

2012 Evidence-Based Mental Health

163. Sibling recurrence rate of autism spectrum disorders is 18.7%

? People 664 infant siblings (≤18 months) of children with autism spectrum disorders (ASDs, including autistic disorder, Asperger's disorder or a pervasive development disorder not otherwise specified). Participants were recruited from ASD clinics and the community. Most sites verified the diagnosis of the older sibling using standardised diagnostic assessments and/or parent diagnostic interviews. Only one infant per family was included in the analysis, and the youngest eligible child was selected (...) Sibling recurrence rate of autism spectrum disorders is 18.7% Sibling recurrence rate of autism spectrum disorders is 18.7% | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user

2012 Evidence-Based Mental Health

164. 2.64% of South Korean children aged 7 to 12 have autism spectrum disorders

2.64% of South Korean children aged 7 to 12 have autism spectrum disorders 2.64% of South Korean children aged 7 to 12 have autism spectrum disorders | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here 2.64% of South Korean children aged 7 to 12 have autism spectrum disorders Article Text Prevalence 2.64% of South Korean children aged 7 to 12 have autism spectrum disorders Statistics from Altmetric.com Question Question What

2012 Evidence-Based Mental Health

165. [Biomedical treatment and diet supplements for the treatment of the autism spectrum disorder]

reported in the scientific literature as an entity in itself. When individually assessing its components, the evidence found is not enough to endorse the use of restrictive diets and/or nutritional supplements as part of the routine treatment of the autism spectrum disorder. Both the clinical practice guidelines and health coverage policies do not endorse the use because they consider them as experimental. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder (...) [Biomedical treatment and diet supplements for the treatment of the autism spectrum disorder] Tratamiento biomédico y suplementos alimentarios para el tratamiento del espectro autista [Biomedical treatment and diet supplements for the treatment of the autism spectrum disorder] Tratamiento biomédico y suplementos alimentarios para el tratamiento del espectro autista [Biomedical treatment and diet supplements for the treatment of the autism spectrum disorder] Pichon Riviere A, Augustovski F

2012 Health Technology Assessment (HTA) Database.

166. Auditory integration training and other sound therapies for autism spectrum disorders (ASD). (Abstract)

Auditory integration training and other sound therapies for autism spectrum disorders (ASD). Auditory integration therapy was developed as a technique for improving abnormal sound sensitivity in individuals with behavioural disorders including autism spectrum disorders. Other sound therapies bearing similarities to auditory integration therapy include the Tomatis Method and Samonas Sound Therapy.To determine the effectiveness of auditory integration therapy or other methods of sound therapy (...) in individuals with autism spectrum disorders.For this update, we searched the following databases in September 2010: CENTRAL (2010, Issue 2), MEDLINE (1950 to September week 2, 2010), EMBASE (1980 to Week 38, 2010), CINAHL (1937 to current), PsycINFO (1887 to current), ERIC (1966 to current), LILACS (September 2010) and the reference lists of published papers. One new study was found for inclusion.Randomised controlled trials involving adults or children with autism spectrum disorders. Treatment

2011 Cochrane

167. Neuron number and size in prefrontal cortex of children with autism. Full Text available with Trip Pro

Neuron number and size in prefrontal cortex of children with autism. Autism often involves early brain overgrowth, including the prefrontal cortex (PFC). Although prefrontal abnormality has been theorized to underlie some autistic symptoms, the cellular defects that cause abnormal overgrowth remain unknown.To investigate whether early brain overgrowth in children with autism involves excess neuron numbers in the PFC. DESIGN, SETTING, AND CASES: Postmortem prefrontal tissue from 7 autistic and 6 (...) ). Brain weight in the autistic cases differed from normative mean weight for age by a mean of 17.6% (95% CI, 10.2%-25.0%; P = .001), while brains in controls differed by a mean of 0.2% (95% CI, -8.7% to 9.1%; P = .96). Plots of counts by weight showed autistic children had both greater total prefrontal neuron counts and brain weight for age than control children.In this small preliminary study, brain overgrowth in males with autism involved an abnormal excess number of neurons in the PFC.

2011 JAMA

168. A meta-analytic study on the effectiveness of comprehensive ABA-based early intervention programs for children with autism spectrum disorders

/post-test design and that evaluating EIBI in young children aged 10 years or under at treatment onset and diagnosed with autism spectrum disorders (Diagnostic and Statistical Manual of Mental Disorders (DSM) -III, DSM-III-R, DSM-IV or International Classification of Diseases Autistic Disorder and Pervasive Developmental Disorder-Not Otherwise Specified) were eligible for inclusion. EIBI had to address all three core deficits in autism using applied behaviour analysis. Eligible outcomes were (...) , Sturmey P. A meta-analytic study on the effectiveness of comprehensive ABA-based early intervention programs for children with autism spectrum disorders. Research in Autism Spectrum Disorders 2011; 5(1): 60-69 DOI Original Paper URL Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder; Behavior Therapy; Child; Child Behavior Disorders; Child Development Disorders, Pervasive; Child, Preschool; Early Intervention (Education); Humans AccessionNumber 12010007347 Date bibliographic

2011 DARE.

169. Therapies for children with autism spectrum disorders.

Therapies for children with autism spectrum disorders. Therapies for children with autism spectrum disorders. Therapies for children with autism spectrum disorders. Warren Z, Veenstra-VanderWeele J, Stone W, Bruzek JL, Nahmias AS, Foss-Feig JH, Jerome RN, Krishnaswami S, Sathe NA, Glasser AM, Surawicz T, McPheeters ML. Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made (...) for the HTA database. Citation Warren Z, Veenstra-VanderWeele J, Stone W, Bruzek JL, Nahmias AS, Foss-Feig JH, Jerome RN, Krishnaswami S, Sathe NA, Glasser AM, Surawicz T, McPheeters ML.. Therapies for children with autism spectrum disorders. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 26. 2011 Authors' objectives The Vanderbilt Evidence-based Practice Center systematically reviewed evidence on therapies for children ages 2 to 12 with autism spectrum

2011 Health Technology Assessment (HTA) Database.

170. SHANK3, the Synapse, and Autism. Full Text available with Trip Pro

SHANK3, the Synapse, and Autism. 21751912 2011 07 22 2012 11 15 1533-4406 365 2 2011 Jul 14 The New England journal of medicine N. Engl. J. Med. SHANK3, the synapse, and autism. 173-5 10.1056/NEJMcibr1104261 Herbert Martha R MR Massachusetts General Hospital and Harvard Medical School, Boston, USA. eng Journal Article United States N Engl J Med 0255562 0028-4793 0 Carrier Proteins 0 Mutant Proteins 0 Nerve Tissue Proteins 0 Shank3 protein, mouse AIM IM N Engl J Med. 2011 Nov 10;365(19):1848 (...) Animals Autistic Disorder genetics pathology physiopathology Carrier Proteins genetics metabolism Corpus Striatum pathology physiopathology Dendrites physiology Mice Mutant Proteins genetics metabolism Nerve Tissue Proteins Synapses genetics metabolism 2011 7 15 6 0 2011 7 15 6 0 2011 7 23 6 0 ppublish 21751912 10.1056/NEJMcibr1104261

2011 NEJM

171. Autism in under 19s: recognition, referral and diagnosis

in both cause and manifestation. DSM-5 refers to autism spectrum disorder as a single condition with different levels of symptom severity in 2 core domains: 1) deficits in social communication and social interaction and 2) restricted repetitive behaviours (RRBs), interests, and activities and sensory anomalies. Autism spectrum disorder encompasses the 4 separate disorders from the previous DSM-IV: autistic disorder (autism), Asperger's disorder, childhood disintegrative disorder and pervasive (...) developmental disorder not otherwise specified. Because both components are required for diagnosis of autism spectrum disorder, social (pragmatic) communication disorder is diagnosed if no RRBs are present. Note that childhood disintegrative disorder is excluded from ASD in DSM-5. The guideline development group recognised that individuals and groups prefer a variety of terms, including autism spectrum disorder, autistic spectrum condition, autistic spectrum difference and neuro-diversity. For clarity

2011 National Institute for Health and Clinical Excellence - Clinical Guidelines

172. Review: secretin is not effective for the treatment of children with autism spectrum disorders

Review: secretin is not effective for the treatment of children with autism spectrum disorders Review: secretin is not effective for the treatment of children with autism spectrum disorders | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: secretin is not effective for the treatment of children with autism spectrum disorders Article Text Therapeutics Review: secretin is not effective for the treatment of children with autism

2011 Evidence-Based Mental Health

173. Review: little evidence of clear benefit for most medical treatments for children with autism spectrum disorders

Review: little evidence of clear benefit for most medical treatments for children with autism spectrum disorders Review: little evidence of clear benefit for most medical treatments for children with autism spectrum disorders | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: little evidence of clear benefit for most medical treatments for children with autism spectrum disorders Article Text Therapeutics Review: little evidence

2011 Evidence-Based Mental Health

174. Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed Full Text available with Trip Pro

, in these times of financial restraint, ensuring that treatments are focused and individually appropriate becomes even more essential. References Lovaas OI . Behavioral treatment and normal educational and intellectual functioning in young autistic children . Howlin P , Magiati I , Charman T . Systematic review of early intensive behavioral interventions for children with autism . Carter AS , Messinger DS , Stone WL , et al . A randomized controlled trial of Hanen's ‘More Than Words’ in toddlers with early (...) Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any

2011 Evidence-Based Mental Health

175. Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Full Text available with Trip Pro

Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Article Text Prevalence Just under 1% of adults living in the community

2011 Evidence-Based Mental Health

176. Social skills training for autistic spectrum disorders

for autism spectrum disorders (ASDs) are nonpharmacological interventions intended to reduce the negative impact of ASD on the child or adolescent and his/her family. Social skills training teaches children or adolescents with ASD to interact, share, and play and work with others, thereby enhancing participation in family, school, and community activities. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder; Behavior Therapys (...) Social skills training for autistic spectrum disorders Social skills training for autistic spectrum disorders Social skills training for autistic spectrum disorders Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Social skills training for autistic spectrum disorders. Lansdale: HAYES, Inc.. Directory Publication. 2011 Authors' conclusions Social skills trainings

2011 Health Technology Assessment (HTA) Database.

177. Intensive behavioral intervention therapy for autism

intervention (IBI) therapy, also known as Lovaas therapy, applied behavior analysis (ABA), or early intensive behavioral intervention (EIBI), is an intensive behavioral treatment program that attempts to improve the cognitive and social functioning of children, primarily young children, with autism. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder; Behavior Therapy; Child Behavior; Child Behavior Disorders; Childs Language (...) Intensive behavioral intervention therapy for autism Intensive behavioral intervention therapy for autism Intensive behavioral intervention therapy for autism Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Intensive behavioral intervention therapy for autism. Lansdale: HAYES, Inc.. Directory Publication. 2011 Authors' conclusions Intensive behavioral

2011 Health Technology Assessment (HTA) Database.

178. For toddlers with autism spectrum disorders, supplementing a comprehensive intervention with interpersonal synchrony improves socially engaged imitation

For toddlers with autism spectrum disorders, supplementing a comprehensive intervention with interpersonal synchrony improves socially engaged imitation For toddlers with autism spectrum disorders, supplementing a comprehensive intervention with interpersonal synchrony improves socially engaged imitation | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn (...) more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here For toddlers with autism spectrum disorders, supplementing a comprehensive

2011 Evidence-Based Mental Health

179. Mitochondrial dysfunction in autism. Full Text available with Trip Pro

Mitochondrial dysfunction in autism. Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism.To evaluate mitochondrial defects in children with autism.Observational study using data collected from patients aged 2 to 5 years who were a subset of children participating (...) in the Childhood Autism Risk From Genes and Environment study in California, which is a population-based, case-control investigation with confirmed autism cases and age-matched, genetically unrelated, typically developing controls, that was launched in 2003 and is still ongoing. Mitochondrial dysfunction and mtDNA abnormalities were evaluated in lymphocytes from 10 children with autism and 10 controls.Oxidative phosphorylation capacity, mtDNA copy number and deletions, mitochondrial rate of hydrogen peroxide

2010 JAMA

180. Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). (Abstract)

Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). Autism spectrum disorders (ASD) are characterised by abnormalities in social interaction and communication skills, as well as stereotypic behaviours and restricted activities and interests. Selective serotonin reuptake inhibitors (SSRIs) are prescribed for the treatment of co-morbidity associated with ASD such as depression, anxiety and obsessive-compulsive behaviours.To determine if treatment with an SSRI: 1 (...) . improves the core features of autism (social interaction, communication and behavioural problems); 2. improves other non-core aspects of behaviour or function such as self-injurious behaviour; 3. improves the quality of life of children and their carers; 4. has short and long term effects on outcome; 5. causes harms.We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2009, Issue 4), MEDLINE ( December 2009), EMBASE (December 2009), CINAHL (December 2009), PsycINFO

2010 Cochrane