Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on autism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

161. Review: secretin is not effective for the treatment of children with autism spectrum disorders

Review: secretin is not effective for the treatment of children with autism spectrum disorders Review: secretin is not effective for the treatment of children with autism spectrum disorders | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: secretin is not effective for the treatment of children with autism spectrum disorders Article Text Therapeutics Review: secretin is not effective for the treatment of children with autism spectrum disorders Statistics from Altmetric.com No Altmetric data available for this article. Question Question Does secretin

Evidence-Based Mental Health2011

162. Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed

Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: possible benefits from early intensive behavioural and developmental interventions in children with autism spectrum disorders, but more research needed Article Text

Evidence-Based Mental Health2011

163. Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders

Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Article Text Prevalence Just under 1% of adults living in the community in England are estimated to have autism spectrum disorders Free Judith Pinborough-Zimmerman , Amanda V Bakian Statistics

Evidence-Based Mental Health2011

166. Improving access to social care for adults with autism

Improving access to social care for adults with autism SCIE - Social Care Institute for Excellence Sharing knowledge, improving lives Sorry � The Social Care Institute for Excellence websites are temporarily unavailable The Social Care Institute for Excellence website is unavailable from the evening of Friday 2 June to early on Monday 4 June. This is due to essential electrical works which will affect our internet server. We are very sorry for the inconvenience and hope to see you back here

Social Care Institute for Excellence2011

168. Autism in under 19s: recognition, referral and diagnosis

Autism in under 19s: recognition, referral and diagnosis Autism spectrum disorder in under 19s: Autism spectrum disorder in under 19s: recognition, referr recognition, referral and diagnosis al and diagnosis Clinical guideline Published: 28 September 2011 nice.org.uk/guidance/cg128 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent (...) . Nothing in this guideline should be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Autism spectrum disorder in under 19s: recognition, referral and diagnosis (CG128) © NICE 2018. All rights reserved. Subject to Notice of rights (https

National Institute for Health and Clinical Excellence - Clinical Guidelines2011

169. Mitochondrial dysfunction in autism.

Mitochondrial dysfunction in autism. CONTEXT: Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism. OBJECTIVE: To evaluate mitochondrial defects in children with autism. DESIGN, SETTING, AND PATIENTS: Observational study using data collected from patients aged 2 to 5 (...) years who were a subset of children participating in the Childhood Autism Risk From Genes and Environment study in California, which is a population-based, case-control investigation with confirmed autism cases and age-matched, genetically unrelated, typically developing controls, that was launched in 2003 and is still ongoing. Mitochondrial dysfunction and mtDNA abnormalities were evaluated in lymphocytes from 10 children with autism and 10 controls. MAIN OUTCOME MEASURES: Oxidative phosphorylation

JAMA2010 Full Text: Link to full Text with Trip Pro

170. Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD).

Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). BACKGROUND: Autism spectrum disorders (ASD) are characterised by abnormalities in social interaction and communication skills, as well as stereotypic behaviours and restricted activities and interests. Selective serotonin reuptake inhibitors (SSRIs) are prescribed for the treatment of co-morbidity associated with ASD such as depression, anxiety and obsessive-compulsive behaviours. OBJECTIVES: To determine (...) if treatment with an SSRI: 1. improves the core features of autism (social interaction, communication and behavioural problems); 2. improves other non-core aspects of behaviour or function such as self-injurious behaviour; 3. improves the quality of life of children and their carers; 4. has short and long term effects on outcome; 5. causes harms. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2009, Issue 4), MEDLINE ( December 2009), EMBASE (December

Cochrane2010

172. Effectiveness of intensive autism programmes

Effectiveness of intensive autism programmes 20189018 2010 03 01 2010 03 15 2017 02 20 1474-547X 375 9716 2010 Feb 27 Lancet (London, England) Lancet Effectiveness of intensive autism programmes. 722-3; author reply 723 10.1016/S0140-6736(10)60299-1 Dawson Michelle M Gernsbacher Morton Ann MA eng F33 DC005365 DC NIDCD NIH HHS United States R01 DC007223 DC NIDCD NIH HHS United States R01 MH069793 MH NIMH NIH HHS United States Comment Letter England Lancet 2985213R 0140-6736 AIM IM Lancet. 2009 (...) Nov 7;374(9701):1627-38 19819542 Lancet. 2011 Nov 19;378(9805):1778 Am J Ment Retard. 2000 Jul;105(4):269-85 10934569 Am J Ment Retard. 2005 Nov;110(6):417-38 16212446 J Clin Child Adolesc Psychol. 2008 Jan;37(1):8-38 18444052 Lancet. 2009 Nov 7;374(9701):1627-38 19819542 Autistic Disorder diagnosis therapy Behavior Therapy methods Child Humans Randomized Controlled Trials as Topic Treatment Outcome NIHMS655565 PMC4301441 2010 3 2 6 0 2010 3 2 6 0 2010 3 17 6 0 ppublish 20189018 S0140-6736(10

Lancet2010 Full Text: Link to full Text with Trip Pro

173. Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model

Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model 19948568 2010 01 05 2010 02 04 2017 02 20 1098-4275 125 1 2010 Jan Pediatrics Pediatrics Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model. e17-23 10.1542/peds.2009-0958 To conduct a randomized, controlled trial to evaluate the efficacy of the Early Start Denver Model (ESDM), a comprehensive developmental behavioral intervention (...) , for improving outcomes of toddlers diagnosed with autism spectrum disorder (ASD). Forty-eight children diagnosed with ASD between 18 and 30 months of age were randomly assigned to 1 of 2 groups: (1) ESDM intervention, which is based on developmental and applied behavioral analytic principles and delivered by trained therapists and parents for 2 years; or (2) referral to community providers for intervention commonly available in the community. Compared with children who received community-intervention

EvidenceUpdates2010

174. Risk of autism and increasing maternal and paternal age in a large north American population

Risk of autism and increasing maternal and paternal age in a large north American population 19783586 2009 10 16 2009 11 04 2009 10 16 1476-6256 170 9 2009 Nov 01 American journal of epidemiology Am. J. Epidemiol. Risk of autism and increasing maternal and paternal age in a large north American population. 1118-26 10.1093/aje/kwp247 Previous studies are inconsistent regarding whether there are independent effects of maternal and paternal age on the risk of autism. Different biologic mechanisms (...) are suggested by maternal and paternal age effects. The study population included all California singletons born in 1989-2002 (n = 7,550,026). Children with autism (n = 23,311) were identified through the California Department of Developmental Services and compared with the remainder of the study population, with parental ages and covariates obtained from birth certificates. Adjusted odds ratios and 95% confidence intervals were used to evaluate the risk of autism associated with increasing maternal

EvidenceUpdates2010

175. Extremely preterm children at increased risk of autism spectrum disorders

Extremely preterm children at increased risk of autism spectrum disorders Extremely preterm children at increased risk of autism spectrum disorders | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Extremely preterm children at increased risk of autism spectrum disorders Article Text Prevalence Extremely preterm children at increased risk of autism spectrum disorders Statistics from Altmetric.com No Altmetric data available for this article. Question Question What is the prevalence of, and correlates for, autism spectrum disorder (ASD) in

Evidence-Based Mental Health2010

176. Fluconazole and pharmaceuticals without inactive ingredients for autism: a review of the clinical effectiveness

Fluconazole and pharmaceuticals without inactive ingredients for autism: a review of the clinical effectiveness Fluconazole and pharmaceuticals without inactive ingredients for autism: a review of the clinical effectiveness Fluconazole and pharmaceuticals without inactive ingredients for autism: a review of the clinical effectiveness Canadian Agency for Drugs and Technologies in Health Record Status This is a bibliographic record of a published health technology assessment from a member (...) of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Canadian Agency for Drugs and Technologies in Health. Fluconazole and pharmaceuticals without inactive ingredients for autism: a review of the clinical effectiveness. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2010 Authors' conclusions The efficacy of antifungal agents for the treatment of autism has not been demonstrated in published clinical trials or observational studies

Health Technology Assessment (HTA) Database.2010

177. Estimated prevalence of autism spectrum conditions in Cambridgeshire is over 1%

Estimated prevalence of autism spectrum conditions in Cambridgeshire is over 1% Estimated prevalence of autism spectrum conditions in Cambridgeshire is over 1% | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Estimated prevalence of autism spectrum conditions in Cambridgeshire is over 1% Article Text Prevalence Estimated prevalence of autism spectrum conditions in Cambridgeshire is over 1% Statistics from Altmetric.com No Altmetric data available for this article. Question Question: What is the prevalence of autism in Cambridgeshire? Population

Evidence-Based Mental Health2010

178. Intensive behavioral intervention therapy for autism

Intensive behavioral intervention therapy for autism Intensive behavioral intervention therapy for autism Intensive behavioral intervention therapy for autism Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Intensive behavioral intervention therapy for autism. Lansdale: HAYES, Inc.. Directory Publication. 2010 Authors' objectives

Intensive behavioral (...) intervention (IBI) therapy, also known as Lovaas therapy, applied behavior analysis (ABA), or early intensive behavioral intervention (EIBI), is an intensive behavioral treatment program that attempts to improve the cognitive and social functioning of children with autism.

Timeliness warning This report has been archived and may contain outdated information. To request a copy of the report please contact the organisation directly. Final publication URL Indexing Status Subject indexing assigned by CRD

Health Technology Assessment (HTA) Database.2010

179. Is video-based instruction effective in the rehabilitation of children with autism spectrum disorders?

Is video-based instruction effective in the rehabilitation of children with autism spectrum disorders? Is video-based instruction effective in the rehabilitation of children with autism spectrum disorders? Is video-based instruction effective in the rehabilitation of children with autism spectrum disorders? Kagohara DM CRD summary This review assessed the effectiveness of video-based instruction for teaching adaptive behaviours to children with autism spectrum disorders. Included studies were (...) small case series or single cases in which introduction and removal of the intervention provided the control. The evidence provided by these studies was not adequate to support the author's conclusion that video-based instruction was an empirically supported intervention. Authors' objectives To assess the effectiveness of video-based instruction for teaching adaptive behaviours to children with autism spectrum disorders. Searching ERIC, SpringerLink, PsycINFO and ProQuest were searched from

DARE.2010

180. Gluten-free and casein-free diets in the treatment of autism spectrum disorders: a systematic review

Gluten-free and casein-free diets in the treatment of autism spectrum disorders: a systematic review Gluten-free and casein-free diets in the treatment of autism spectrum disorders: a systematic review Gluten-free and casein-free diets in the treatment of autism spectrum disorders: a systematic review Mulloy A, Lang R, O'Reilly M, Sigafoos J, Lancioni G, Rispoli M CRD summary This review concluded that the evidence did not support use of gluten-free and/or casein-free diets in the treatment (...) of ASD. The studies included in this review had very small sample sizes and were of poor quality. The authors' conclusions appear reliable in reflecting the limited evidence. Authors' objectives To investigate the effects of gluten-free and/or casein-free (GFCF) diets in the treatment of autism spectrum disorder (ASD). Searching English-language peer-reviewed studies were identified through a search of PsycINFO, Psychology and Behavioural Sciences Collection, ERIC and MEDLINE. Search terms were

DARE.2010