Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

122. Autism and mental retardation among offspring born after in vitro fertilization.

Autism and mental retardation among offspring born after in vitro fertilization. IMPORTANCE: Between 1978 and 2010, approximately 5 million infants were born after in vitro fertilization (IVF) treatments. Yet limited information on neurodevelopment after IVF exists, especially after the first year of life. OBJECTIVE: To examine the association between use of any IVF and different IVF procedures and the risk of autistic disorder and mental retardation in the offspring. DESIGN, SETTING (...) , AND PARTICIPANTS: A population-based, prospective cohort study using Swedish national health registers. Offspring born between 1982 and 2007 were followed up for a clinical diagnosis of autistic disorder or mental retardation until December 31, 2009. The exposure of interest was IVF, categorized according to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh or frozen. For ICSI, whether sperm were ejaculated or surgically extracted was also considered

JAMA2013

123. Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence

Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Berry A, Borgi M, Francia N, Alleva E, Cirulli F CRD summary This poorly reported review concluded that studies were encouraging (...) and indicated therapy or assistance dogs could promote positive behaviours in children diagnosed with autism spectrum disorders, but called for further research. The results cannot be considered reliable given the apparent variability in the small evidence base. Authors' objectives To provide a critical review of the literature assessing the effects of therapy and assistance dogs on children with autism spectrum disorders and their families. Searching PubMed, ERIC, Science Direct, Google Scholar, reference

DARE.2013

124. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada

Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada 22947654 2013 01 16 2013 03 11 2013 01 16 1097-6833 162 2 2013 Feb The Journal of pediatrics J. Pediatr. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada. 361-8 10.1016/j.jpeds.2012.07.040 S0022-3476(12)00865-7 To examine the association between autism spectrum disorders (ASD) and each completed week of gestation using a graphical method of presenting results at all possible

EvidenceUpdates2013

126. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children.

Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. IMPORTANCE: Prenatal folic acid supplements reduce the risk of neural tube defects in children, but it has not been determined whether they protect against other neurodevelopmental disorders. OBJECTIVE: To examine the association between maternal use of prenatal folic acid supplements and subsequent risk of autism spectrum disorders (ASDs) (autistic disorder, Asperger syndrome (...) , defined as the first day of the last menstrual period before conception. Relative risks of ASDs were estimated by odds ratios (ORs) with 95% CIs in a logistic regression analysis. Analyses were adjusted for maternal education level, year of birth, and parity. MAIN OUTCOME MEASURE: Specialist-confirmed diagnosis of ASDs. RESULTS: At the end of follow-up, 270 children in the study sample had been diagnosed with ASDs: 114 with autistic disorder, 56 with Asperger syndrome, and 100 with PDD-NOS

JAMA2013 Full Text: Link to full Text with Trip Pro

127. Can we change the risk of autism?

Can we change the risk of autism? 23403688 2013 02 13 2013 02 19 2016 10 25 1538-3598 309 6 2013 Feb 13 JAMA JAMA Periconceptional folic acid and risk of autism spectrum disorders. 611-3 10.1001/jama.2013.198 Berry Robert J RJ Crider Krista S KS Yeargin-Allsopp Marshalyn M eng CC999999 Intramural CDC HHS United States Comment Editorial Research Support, U.S. Gov't, P.H.S. United States JAMA 7501160 0098-7484 12001-76-2 Vitamin B Complex 935E97BOY8 Folic Acid AIM IM Lancet. 2009 Nov 7;374(9701 (...) 21;338(6114):1619-22 23160955 Autism Res. 2008 Feb;1(1):4-17 19360646 Pediatrics. 2005 Sep;116(3):703-8 16140711 Med Hypotheses. 2008 Sep;71(3):406-10 18514430 JAMA. 2013 Feb 13;309(6):570-7 23403681 Child Development Disorders, Pervasive epidemiology prevention & control Female Folic Acid therapeutic use Humans Male Pregnancy Prenatal Exposure Delayed Effects Vitamin B Complex therapeutic use HHSPA698519 PMC4468781 2013 2 14 6 0 2013 2 14 6 0 2013 2 21 6 0 ppublish 23403688 1570262 10.1001/jama

JAMA2013 Full Text: Link to full Text with Trip Pro

128. Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder

Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder Article Text Aetiology Children

Evidence-Based Mental Health2013

129. Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder

Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Article Text Therapeutics Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Statistics from

Evidence-Based Mental Health2013

130. Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age

Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Article Text Aetiology Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Statistics from Altmetric.com

Evidence-Based Mental Health2013

131. Cohort study: Maternal folic acid supplements associated with reduced autism risk in the child

Cohort study: Maternal folic acid supplements associated with reduced autism risk in the child Maternal folic acid supplements associated with reduced autism risk in the child | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Maternal folic acid supplements associated with reduced autism risk in the child Article Text Aetiology Cohort study Maternal folic acid supplements associated with reduced autism risk in the child Rebecca J Schmidt Statistics from Altmetric.com No Altmetric data available for this article. Commentary on: Surén P , Roth C

Evidence-Based Medicine (Requires free registration)2013 Full Text: Link to full Text with Trip Pro

132. Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed

Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed Article Text Therapeutics Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed

Evidence-Based Mental Health2013

133. Autism in under 19s: support and management

Autism in under 19s: support and management Autism spectrum disorder in under 19s: Autism spectrum disorder in under 19s: support and management support and management Clinical guideline Published: 28 August 2013 nice.org.uk/guidance/cg170 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful (...) in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Autism spectrum disorder in under 19s: support and management (CG170) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2

National Institute for Health and Clinical Excellence - Clinical Guidelines2013

134. Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes

Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes 404 - The Campbell Collaboration Media Centre Blog Newsletter Sign Up Menu or search for what you are looking for in the search box above Useful Links News and Jobs Twitter Copyright © 2017 Campbell Collaboration. All Rights Reserved

Campbell Collaboration2013

135. Autism ? complementary home-based care

Autism ? complementary home-based care Occupational Therapy and Physical Therapy/Autism/Home Based Services/BESt 131 Best Evidence Statement (BESt) Copyright © 2013 Cincinnati Children's Hospital Medical Center; all rights reserved Page 1 of 6 Date: 2/6/13 Title: Adding home based services to complement center based intervention for children with autism Clinical Question: Definitions for terms marked with * may be found in the Supporting Information section. Target Population (...) after one year (Rickards 2009 [2a], Rickards 2007 [2a]). Drew revealed that the addition of home based developmental intervention significantly improved words understood, words said and P (Population/Problem) Among children under the age of 6 years old with autism spectrum disorder (ASD) or pervasive developmental disorder - not otherwise specified and their parents I (Intervention) does home based developmental intervention in addition to center based developmental intervention* C (Comparison

Cincinnati Children's Hospital Medical Center2013

136. Clinical genetic evaluation in identifying the etiology of the autism spectrum disorders: 2013 guideline revisions

Clinical genetic evaluation in identifying the etiology of the autism spectrum disorders: 2013 guideline revisions 1 © American College of Medical Genetics and Genomics ACMG PrACtiCe Guidelines Autism spectrum disorders (ASDs), also known as pervasive developmental disorders, are a behaviorally defined group of neurodevelopmental disorders that are usually diagnosed in early childhood. They are characterized by varying degrees of limitations in communication and social interaction (...) and by atypical, repetitive behaviors with an onset before 3 years of age. The phenotype of ASDs is extremely heterogeneous, with differences from person to person in a wide range of symptoms and severity as well as differences between the various subtypes of ASDs (e.g., autistic disorder, Asperger syndrome, and perva- sive developmental disorder not otherwise specified). Multiple lines of epidemiologic evidence support the strong role of genetics in the etiology of ASDs. 1–3 Results of popula- tion studies

American College of Medical Genetics and Genomics 2013

137. Sensory integration therapy for autism spectrum disorders: a systematic review

Sensory integration therapy for autism spectrum disorders: a systematic review Sensory integration therapy for autism spectrum disorders: a systematic review Sensory integration therapy for autism spectrum disorders: a systematic review Lang R, O'Reilly M, Healy O, Rispoli M, Lydon H, Streusand W, Davis T, Kang S, Sigafoos J, Lancioni G, Didden R, Giesbers S CRD summary The authors concluded that sensory integration therapy had no consistently positive effect as a treatment for children (...) with autism spectrum disorders. Despite some potential methodological flaws in the review the conclusion reflects the evidence presented and seems likely to be reliable. Authors' objectives To evaluate the effects of sensory integration therapy in the education and treatment of people with autism spectrum disorders. Searching MEDLINE, ERIC, Psychology and Behavioural Sciences Collection and PsycINFO were searched for peer-reviewed studies in English. Search terms were reported. Reference lists were

DARE.2012

138. Massage therapy for autism spectrum disorders in children

Massage therapy for autism spectrum disorders in children Massage therapy for autism spectrum disorders in children Massage therapy for autism spectrum disorders in children Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Massage therapy for autism spectrum disorders in children. Lansdale: HAYES, Inc.. Directory Publication. 2012 Authors' conclusions Massage (...) therapy for children diagnosed with autism spectrum disorder and pervasive developmental disorder is designed to improve abnormalities in sensory processing and sensory integration that are prevalent in these complex disorders, and to ultimately improve cognitive, behavioral, and social functioning of autistic individuals. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder; Child; Child Behavior Disorders; Child Development

Health Technology Assessment (HTA) Database.2012

139. Tricyclic antidepressants for autism spectrum disorders (ASD) in children and adolescents.

Tricyclic antidepressants for autism spectrum disorders (ASD) in children and adolescents. BACKGROUND: Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders, ranging in severity and characterised by early onset of delay and deviance in the development of social interaction, and verbal and nonverbal communication. ASD is associated with restricted and/or stereotyped interests or behaviours. Tricyclic antidepressants (TCAs) block noradrenaline and serotonin (...) reuptake, increasing the availability of these neurotransmitters in the central nervous system. Via their impact on serotonin, TCAs have been used in the treatment of autistic symptoms and comorbidities in individuals with ASD. OBJECTIVES: To determine if treatment with tricyclic antidepressants:1) improves the core features of autism, including restricted social interaction, restricted communication, and stereotypical and repetitive behaviours; 2) improves non-core features such as challenging

Cochrane2012

140. Atomoxetine reduces ADHD symptoms in children with autism spectrum disorder

Atomoxetine reduces ADHD symptoms in children with autism spectrum disorder Atomoxetine reduces ADHD symptoms in children with autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Atomoxetine reduces ADHD symptoms in children with autism spectrum disorder Article Text Therapeutics Atomoxetine reduces ADHD symptoms in children with autism spectrum disorder Statistics from Altmetric.com No Altmetric data available for this article. Question Question: Does atomoxetine reduce symptoms of attention deficit/hyperactivity (ADHD

Evidence-Based Mental Health2012