Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

121. Screening and diagnostic tools for autism spectrum disorder in children: a review of guidelines

Autism Rating Scale (CARS) were the recommended tools for use when diagnosing ASD in those guidelines advocating their use. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorders; Child; Mass Screening Language Published English Country of organisation Canada Province or state Ontario English summary An English language summary is available. Address for correspondence Canadian Agency for Drugs and Technologies in Health (CADTH), 865 Carling Avenue, Suite 600 (...) Screening and diagnostic tools for autism spectrum disorder in children: a review of guidelines Screening and diagnostic tools for autism spectrum disorder in children: a review of guidelines Screening and diagnostic tools for autism spectrum disorder in children: a review of guidelines CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database

2014 Health Technology Assessment (HTA) Database.

122. Theory of mind interventions can be effective in treating autism, although long-term success remains unproven Full Text available with Trip Pro

Theory of mind interventions can be effective in treating autism, although long-term success remains unproven Theory of mind interventions can be effective in treating autism, although long-term success remains unproven | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Theory of mind interventions can be effective in treating autism, although long-term success remains unproven Article Text Miscellaneous Theory of mind interventions

2014 Evidence-Based Mental Health

123. Neonatal factors associated with autism spectrum disorders in infants Full Text available with Trip Pro

Neonatal factors associated with autism spectrum disorders in infants Neonatal factors associated with autism spectrum disorders in infants | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Neonatal factors associated with autism spectrum disorders in infants Article Text Prevalence, assessment and diagnosis Neonatal factors associated with autism spectrum disorders in infants Sara Jane Webb Statistics from Altmetric.com What

2014 Evidence-Based Mental Health

124. Early Intensive Behavioral Intervention (EIBI) for Young Children with Autism Spectrum Disorders (ASD): A Systematic Review Full Text available with Trip Pro

of participants Young children with Autistic Disorder, Asperger's Disorder, Pervasive Developmental Disorder, not otherwise specified, or Atypical Autism ( ; )who are younger than six years old at the onset of treatment (that is, all participants within a group must be younger than six years old). Participants were not excluded based on IQ or presence of comorbidities. 3.1.3 Types of interventions EIBI as defined above, compared with no treatment, with waitlist controls, or treatment as usual (TAU). TAU often (...) specified children could have a diagnosis of autistic disorder or PDD‐NOS. The diagnoses of ASD were further confirmed in three of the five studies by using the ADI‐R. All studies specified that children could not have any other major medical conditions that would interfere with participation in the treatment. Two studies specified an IQ inclusion criterion. In children with autism had to have an IQ of 35 to 75 at treatment entry; in children with autism had to have an IQ of greater than 35. Across

2014 Campbell Collaboration

125. Autism traits may be more prevalent in ADHD than previously reported

Autism traits may be more prevalent in ADHD than previously reported Autism traits may be more prevalent in ADHD than previously reported | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password (...) * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Autism traits may be more prevalent in ADHD than previously reported Article Text Prevalence, assessment and diagnosis Autism traits may be more prevalent in ADHD than previously reported Kevin Antshel Statistics from Altmetric.com What is already known

2014 Evidence-Based Mental Health

126. Labor Induction or Augmentation and Autism

Labor Induction or Augmentation and Autism Labor Induction or Augmentation and Autism - ACOG Menu ▼ Labor Induction or Augmentation and Autism Page Navigation ▼ Number 597, May 2014 (Reaffirmed 2018) Committee on Obstetric Practice The Society for Maternal-Fetal Medicine endorses this document. This document reflects emerging clinical and scientific advances as of the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment (...) or procedure to be followed. Labor Induction or Augmentation and Autism Abstract: Functional oxytocin deficiency and a faulty oxytocin signaling pathway have been observed in conjunction with autism spectrum disorder (ASD). Because exogenous synthetic oxytocin commonly is administered for labor induction and augmentation, some have hypothesized that synthetic oxytocin used for these purposes may alter fetal oxytocin receptors and predispose exposed offspring to ASD. However, current evidence does

2014 American College of Obstetricians and Gynecologists

127. Autism

search covered the period from 1991 to March 19, 2013 using the PubMed, PsycINFO, Cochrane, and CINAHL (EBSCO) databases. The initial searches were inclusive and sensitive. Search terms were a combination of MeSH headings and keywords, and the MeSH headings were adjusted to terms used by PsycINFO and CINAHL by using their thesauri. In PubMed the MeSH terms autistic disorder, childhood development disorders—pervasive, Asperger*, and Rett* and the keyword autism were searched. The initial search (...) OF CHILD & ADOLESCENT PSYCHIATRY VOLUME 53 NUMBER 2 FEBRUARY 2014 www.jaacap.org 237andvalidationstudies.There?nedPubMedsearch yielded3,613articles. In the PsycINFO database subject headings (focused) of autism, autistic thinking, pervasive developmental disorders, retts syndrome, aspergers, and keyword autism were searched. The initial search returned 24,875 articles and was then limited to English, childhood: birth to age 12yrs, adolescence: age 13-17 yrs, peer reviewed journal,and 1991 to March 19

2014 American Academy of Child and Adolescent Psychiatry

128. [Overview of the drugs used by children and adolescents diagnosed with autism spectrum disorder who are covered by the Public Prescription Drug Insurance Plan]

[Overview of the drugs used by children and adolescents diagnosed with autism spectrum disorder who are covered by the Public Prescription Drug Insurance Plan] Portrait de l'usage des médicaments chez les enfants et les adolescents ayant reçu un diagnostic de troubles du spectre de l'autisme couverts par le régime public d'assurance médicaments [Overview of the drugs used by children and adolescents diagnosed with autism spectrum disorder who are covered by the Public Prescription Drug (...) Insurance Plan] Portrait de l'usage des médicaments chez les enfants et les adolescents ayant reçu un diagnostic de troubles du spectre de l'autisme couverts par le régime public d'assurance médicaments [Overview of the drugs used by children and adolescents diagnosed with autism spectrum disorder who are covered by the Public Prescription Drug Insurance Plan] Turgeon M, Tremblay E, Déry N, Guay H Record Status This is a bibliographic record of a published health technology assessment from a member

2014 Health Technology Assessment (HTA) Database.

129. Cohort study: Prenatal exposure to sodium valproate is associated with increased risk of childhood autism and autistic spectrum disorder

Cohort study: Prenatal exposure to sodium valproate is associated with increased risk of childhood autism and autistic spectrum disorder Prenatal exposure to sodium valproate is associated with increased risk of childhood autism and autistic spectrum disorder | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Prenatal exposure to sodium valproate is associated with increased risk of childhood autism and autistic spectrum disorder Article Text

2014 Evidence-Based Nursing

130. Applied behavior analysis-based interventions for autism spectrum disorder

Applied behavior analysis-based interventions for autism spectrum disorder Applied behavior analysis-based interventions for autism spectrum disorder Applied behavior analysis-based interventions for autism spectrum disorder Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Applied behavior analysis-based interventions for autism spectrum disorder. Lansdale: HAYES (...) , Inc.. Directory Publication. 2014 Authors' objectives The methods and principles of applied behavior analysis (ABA) have been used to design intensive and comprehensive behavioral treatment programs that attempt to improve outcomes in children, especially young children, who have autism spectrum disorder (ASD). ABA-based programs are generally referred to as intensive behavioral intervention (IBI). The Early Start Denver Model (ESDM) program includes ABA in combination with developmental

2014 Health Technology Assessment (HTA) Database.

131. Motor interventions for autism spectrum disorder in children: clinical effectiveness and guidelines

Motor interventions for autism spectrum disorder in children: clinical effectiveness and guidelines Motor interventions for autism spectrum disorder in children: clinical effectiveness and guidelines Motor interventions for autism spectrum disorder in children: clinical effectiveness and guidelines CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA (...) database. Citation CADTH. Motor interventions for autism spectrum disorder in children: clinical effectiveness and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions One systematic review, six randomized controlled trials, 22 non-randomized studies, and two evidence-based guidelines regarding the clinical effectiveness of motor interventions for children with autism spectrum disorders were identified. Final publication URL

2014 Health Technology Assessment (HTA) Database.

132. Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. Full Text available with Trip Pro

Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. Studies have raised concern about an association between the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy and an increased risk of autism spectrum disorders in the offspring.We conducted a cohort study of all singleton live births in Denmark from 1996 through 2005 (626,875 births), with follow-up through 2009. Using Danish population registries, we linked information on maternal use (...) of SSRIs before and during pregnancy, autism spectrum disorders diagnosed in the offspring, and a range of potential confounders. We used a survival analysis of the time to diagnosis in the offspring with Poisson regression to estimate rate ratios of autism spectrum disorders according to maternal use of SSRIs.During 5,057,282 person-years of follow-up, we identified 3892 cases of autism spectrum disorder (incidence rate, 77.0 per 100,000 person-years). A total of 52 cases during 42,400 person-years

2013 NEJM

133. Autism. (Abstract)

Autism. Autism is a set of heterogeneous neurodevelopmental conditions, characterised by early-onset difficulties in social communication and unusually restricted, repetitive behaviour and interests. The worldwide population prevalence is about 1%. Autism affects more male than female individuals, and comorbidity is common (>70% have concurrent conditions). Individuals with autism have atypical cognitive profiles, such as impaired social cognition and social perception, executive dysfunction (...) , and atypical perceptual and information processing. These profiles are underpinned by atypical neural development at the systems level. Genetics has a key role in the aetiology of autism, in conjunction with developmentally early environmental factors. Large-effect rare mutations and small-effect common variants contribute to risk. Assessment needs to be multidisciplinary and developmental, and early detection is essential for early intervention. Early comprehensive and targeted behavioural interventions

2013 Lancet

134. Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). (Abstract)

Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). Autism spectrum disorders (ASD) are characterised by abnormalities in social interaction and communication skills, as well as stereotypic behaviours and restricted activities and interests. Selective serotonin reuptake inhibitors (SSRIs) are prescribed for the treatment of conditions often comorbid with ASD such as depression, anxiety and obsessive-compulsive behaviours.To determine if treatment with an SSRI:1 (...) . improves the core features of autism (social interaction, communication and behavioural problems);2. improves other non-core aspects of behaviour or function such as self-injurious behaviour;3. improves the quality of life of adults or children and their carers;4. has short- and long-term effects on outcome;5. causes harm.We searched the following databases up until March 2013: CENTRAL, Ovid MEDLINE, Embase, CINAHL, PsycINFO, ERIC and Sociological Abstracts. We also searched ClinicalTrials.gov

2013 Cochrane

135. Screening and Diagnostic Tools for Autism Spectrum Disorder in Children: A Review of Guidelines

Screening and Diagnostic Tools for Autism Spectrum Disorder in Children: A Review of Guidelines TITLE: Screening and Diagnostic Tools for Autism Spectrum Disorder in Children: A Review of Guidelines DATE: 03 July 2013 CONTEXT AND POLICY ISSUES Autism is a lifelong condition that involves impaired verbal and non-verbal communication, impaired socialization, and repetitive or restricted patterns of behaviour. 1-4 Autism spectrum disorders (ASD) refer to a range of disorders that include autistic (...) for additional research for better validation was indicated for the following second level screening tools, despite some of these being simultaneously recommended for use: Early Screening for Autistic Traits (ESAT), M-CHAT, Pervasive Developmental Disorder Screening Test-II (PDDST-II), the STAT, and the Social Communication Questionnaire (SCQ). 3 The Autism Behaviour Checklist (ASD) and Gilliam Autism Rating Scale (GARS) were not recommended for second level screening as these tools reported low sensitivity

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

136. Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders

Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Record Status This is a bibliographic record of a published health technology (...) assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders. Lansdale: HAYES, Inc.. Genetic Testing Publication. 2013 Authors' conclusions Chromosome abnormalities are a common cause of developmental delay (DD), intellectual disability (ID), multiple congenital anomalies (MCA), and other neurodevelopmental disorders

2013 Health Technology Assessment (HTA) Database.

137. Autism and mental retardation among offspring born after in vitro fertilization. Full Text available with Trip Pro

Autism and mental retardation among offspring born after in vitro fertilization. Between 1978 and 2010, approximately 5 million infants were born after in vitro fertilization (IVF) treatments. Yet limited information on neurodevelopment after IVF exists, especially after the first year of life.To examine the association between use of any IVF and different IVF procedures and the risk of autistic disorder and mental retardation in the offspring.A population-based, prospective cohort study using (...) Swedish national health registers. Offspring born between 1982 and 2007 were followed up for a clinical diagnosis of autistic disorder or mental retardation until December 31, 2009. The exposure of interest was IVF, categorized according to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh or frozen. For ICSI, whether sperm were ejaculated or surgically extracted was also considered.Relative risks (RRs) for autistic disorder and mental

2013 JAMA

138. Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Full Text available with Trip Pro

Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Berry A, Borgi M, Francia N, Alleva E, Cirulli F CRD summary This poorly reported review concluded that studies were encouraging (...) and indicated therapy or assistance dogs could promote positive behaviours in children diagnosed with autism spectrum disorders, but called for further research. The results cannot be considered reliable given the apparent variability in the small evidence base. Authors' objectives To provide a critical review of the literature assessing the effects of therapy and assistance dogs on children with autism spectrum disorders and their families. Searching PubMed, ERIC, Science Direct, Google Scholar, reference

2013 DARE.

139. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada (Abstract)

Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada To examine the association between autism spectrum disorders (ASD) and each completed week of gestation using a graphical method of presenting results at all possible categorizations of gestational age (GA).The risk of ASD in a total of 218110 singleton live births with complete data from Alberta, Canada between 1998 and 2004 was examined through linkage to health insurance records. The relative risk of developing

2013 EvidenceUpdates

140. Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders

research focused on interventions for adolescents and young adults between the ages of 13 and 30 with autism spectrum disorder (ASD; autistic disorder, Asperger’s syndrome, pervasive developmental disorder–not otherwise specified). We addressed questions related to: the effectiveness of therapies targeting core symptoms of ASD (impairments in communication, social interaction, and behavior); common medical or mental health comorbidities, including associated symptoms such as irritability; the process (...) Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Future Research Needs Paper Number 20 Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Future Research Needs Paper Number 20 Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders Identification of Future Research Needs From Comparative Effectiveness Review No. 65 Prepared for: Agency for Healthcare

2013 Effective Health Care Program (AHRQ)