Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on autism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

101. Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism.

Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. BACKGROUND: Studies have raised concern about an association between the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy and an increased risk of autism spectrum disorders in the offspring. METHODS: We conducted a cohort study of all singleton live births in Denmark from 1996 through 2005 (626,875 births), with follow-up through 2009. Using Danish population registries, we linked (...) information on maternal use of SSRIs before and during pregnancy, autism spectrum disorders diagnosed in the offspring, and a range of potential confounders. We used a survival analysis of the time to diagnosis in the offspring with Poisson regression to estimate rate ratios of autism spectrum disorders according to maternal use of SSRIs. RESULTS: During 5,057,282 person-years of follow-up, we identified 3892 cases of autism spectrum disorder (incidence rate, 77.0 per 100,000 person-years). A total of 52

NEJM2013

102. Autism.

Autism. Autism is a set of heterogeneous neurodevelopmental conditions, characterised by early-onset difficulties in social communication and unusually restricted, repetitive behaviour and interests. The worldwide population prevalence is about 1%. Autism affects more male than female individuals, and comorbidity is common (>70% have concurrent conditions). Individuals with autism have atypical cognitive profiles, such as impaired social cognition and social perception, executive dysfunction (...) , and atypical perceptual and information processing. These profiles are underpinned by atypical neural development at the systems level. Genetics has a key role in the aetiology of autism, in conjunction with developmentally early environmental factors. Large-effect rare mutations and small-effect common variants contribute to risk. Assessment needs to be multidisciplinary and developmental, and early detection is essential for early intervention. Early comprehensive and targeted behavioural interventions

Lancet2013

103. Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD).

Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). BACKGROUND: Autism spectrum disorders (ASD) are characterised by abnormalities in social interaction and communication skills, as well as stereotypic behaviours and restricted activities and interests. Selective serotonin reuptake inhibitors (SSRIs) are prescribed for the treatment of conditions often comorbid with ASD such as depression, anxiety and obsessive-compulsive behaviours. OBJECTIVES: To determine (...) if treatment with an SSRI:1. improves the core features of autism (social interaction, communication and behavioural problems);2. improves other non-core aspects of behaviour or function such as self-injurious behaviour;3. improves the quality of life of adults or children and their carers;4. has short- and long-term effects on outcome;5. causes harm. SEARCH METHODS: We searched the following databases up until March 2013: CENTRAL, Ovid MEDLINE, Embase, CINAHL, PsycINFO, ERIC and Sociological Abstracts. We

Cochrane2013

104. Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders

Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders Record Status This is a bibliographic record of a published health technology (...) assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Genomic microarray analysis for intellectual disability, developmental delay, multiple congenital anomalies, and autism spectrum disorders. Lansdale: HAYES, Inc.. Genetic Testing Publication. 2013 Authors' conclusions Chromosome abnormalities are a common cause of developmental delay (DD), intellectual disability (ID), multiple congenital anomalies (MCA), and other neurodevelopmental disorders

Health Technology Assessment (HTA) Database.2013

106. Autism and mental retardation among offspring born after in vitro fertilization.

Autism and mental retardation among offspring born after in vitro fertilization. IMPORTANCE: Between 1978 and 2010, approximately 5 million infants were born after in vitro fertilization (IVF) treatments. Yet limited information on neurodevelopment after IVF exists, especially after the first year of life. OBJECTIVE: To examine the association between use of any IVF and different IVF procedures and the risk of autistic disorder and mental retardation in the offspring. DESIGN, SETTING (...) , AND PARTICIPANTS: A population-based, prospective cohort study using Swedish national health registers. Offspring born between 1982 and 2007 were followed up for a clinical diagnosis of autistic disorder or mental retardation until December 31, 2009. The exposure of interest was IVF, categorized according to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh or frozen. For ICSI, whether sperm were ejaculated or surgically extracted was also considered

JAMA2013

107. Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence

Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence Berry A, Borgi M, Francia N, Alleva E, Cirulli F CRD summary This poorly reported review concluded that studies were encouraging (...) and indicated therapy or assistance dogs could promote positive behaviours in children diagnosed with autism spectrum disorders, but called for further research. The results cannot be considered reliable given the apparent variability in the small evidence base. Authors' objectives To provide a critical review of the literature assessing the effects of therapy and assistance dogs on children with autism spectrum disorders and their families. Searching PubMed, ERIC, Science Direct, Google Scholar, reference

DARE.2013

108. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada

Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada 22947654 2013 01 16 2013 03 11 2013 01 16 1097-6833 162 2 2013 Feb The Journal of pediatrics J. Pediatr. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada. 361-8 10.1016/j.jpeds.2012.07.040 S0022-3476(12)00865-7 To examine the association between autism spectrum disorders (ASD) and each completed week of gestation using a graphical method of presenting results at all possible

EvidenceUpdates2013

110. Can we change the risk of autism?

Can we change the risk of autism? 23403688 2013 02 13 2013 02 19 2016 10 25 1538-3598 309 6 2013 Feb 13 JAMA JAMA Periconceptional folic acid and risk of autism spectrum disorders. 611-3 10.1001/jama.2013.198 Berry Robert J RJ Crider Krista S KS Yeargin-Allsopp Marshalyn M eng CC999999 Intramural CDC HHS United States Comment Editorial Research Support, U.S. Gov't, P.H.S. United States JAMA 7501160 0098-7484 12001-76-2 Vitamin B Complex 935E97BOY8 Folic Acid AIM IM Lancet. 2009 Nov 7;374(9701 (...) 21;338(6114):1619-22 23160955 Autism Res. 2008 Feb;1(1):4-17 19360646 Pediatrics. 2005 Sep;116(3):703-8 16140711 Med Hypotheses. 2008 Sep;71(3):406-10 18514430 JAMA. 2013 Feb 13;309(6):570-7 23403681 Child Development Disorders, Pervasive epidemiology prevention & control Female Folic Acid therapeutic use Humans Male Pregnancy Prenatal Exposure Delayed Effects Vitamin B Complex therapeutic use HHSPA698519 PMC4468781 2013 2 14 6 0 2013 2 14 6 0 2013 2 21 6 0 ppublish 23403688 1570262 10.1001/jama

JAMA2013 Full Text: Link to full Text with Trip Pro

111. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children.

Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. IMPORTANCE: Prenatal folic acid supplements reduce the risk of neural tube defects in children, but it has not been determined whether they protect against other neurodevelopmental disorders. OBJECTIVE: To examine the association between maternal use of prenatal folic acid supplements and subsequent risk of autism spectrum disorders (ASDs) (autistic disorder, Asperger syndrome (...) , defined as the first day of the last menstrual period before conception. Relative risks of ASDs were estimated by odds ratios (ORs) with 95% CIs in a logistic regression analysis. Analyses were adjusted for maternal education level, year of birth, and parity. MAIN OUTCOME MEASURE: Specialist-confirmed diagnosis of ASDs. RESULTS: At the end of follow-up, 270 children in the study sample had been diagnosed with ASDs: 114 with autistic disorder, 56 with Asperger syndrome, and 100 with PDD-NOS

JAMA2013 Full Text: Link to full Text with Trip Pro

112. Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed

Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed Article Text Therapeutics Review: more RCTs on early intensive behavioural intervention for young children with autism spectrum disorders needed

Evidence-Based Mental Health2013

113. Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age

Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Article Text Aetiology Autism spectrum disorders are associated with fetal growth extremely below or above average for gestational age Statistics from Altmetric.com

Evidence-Based Mental Health2013

114. Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder

Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Children of migrant parents may be at greater risk of low-functioning autism spectrum disorder, but lower risk of high-functioning autism spectrum disorder Article Text Aetiology Children

Evidence-Based Mental Health2013

115. Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder

Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Article Text Therapeutics Review: social skills groups may improve social competence in children and adolescents with autism spectrum disorder Statistics from

Evidence-Based Mental Health2013

116. Cohort study: Maternal folic acid supplements associated with reduced autism risk in the child

Cohort study: Maternal folic acid supplements associated with reduced autism risk in the child Maternal folic acid supplements associated with reduced autism risk in the child | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Maternal folic acid supplements associated with reduced autism risk in the child Article Text Aetiology Cohort study Maternal folic acid supplements associated with reduced autism risk in the child Rebecca J Schmidt Statistics from Altmetric.com No Altmetric data available for this article. Commentary on: Surén P , Roth C

Evidence-Based Medicine (Requires free registration)2013

117. Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes

Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes 404 - The Campbell Collaboration Media Centre Blog Newsletter Sign Up Menu or search for what you are looking for in the search box above Useful Links News and Jobs Twitter Copyright © 2017 Campbell Collaboration. All Rights Reserved

Campbell Collaboration2013