Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on autism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

41. Miscellaneous: Disruptive behaviour may hinder the acquisition of daily living skills for youth with autism spectrum disorder

Miscellaneous: Disruptive behaviour may hinder the acquisition of daily living skills for youth with autism spectrum disorder Disruptive behaviour may hinder the acquisition of daily living skills for youth with autism spectrum disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Disruptive behaviour may hinder the acquisition of daily living skills for youth with autism spectrum disorder Article Text Electronic pages Miscellaneous Disruptive behaviour may hinder the acquisition of daily living skills for youth with autism spectrum

Evidence-Based Mental Health2017

42. Cognitive-behavioural group therapy for youth with high-functioning autism spectrum disorders demonstrates modest effects on social responsiveness

Cognitive-behavioural group therapy for youth with high-functioning autism spectrum disorders demonstrates modest effects on social responsiveness Cognitive-behavioural group therapy for youth with high-functioning autism spectrum disorders demonstrates modest effects on social responsiveness | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Cognitive-behavioural group therapy for youth with high-functioning autism spectrum disorders demonstrates modest effects on social responsiveness Article Text Psychological interventions Cognitive-behavioural group

Evidence-Based Mental Health2017

44. Thalamocortical dysconnectivity in autism spectrum disorder: An analysis of the Autism Brain Imaging Data Exchange

Thalamocortical dysconnectivity in autism spectrum disorder: An analysis of the Autism Brain Imaging Data Exchange 28584881 2018 11 13 2451-9030 2 1 2017 Jan Biological psychiatry. Cognitive neuroscience and neuroimaging Biol Psychiatry Cogn Neurosci Neuroimaging Thalamocortical dysconnectivity in autism spectrum disorder: An analysis of the Autism Brain Imaging Data Exchange. 76-84 10.1016/j.bpsc.2016.09.002 Individuals with autism spectrum disorder (ASD) exhibit differences in basic (...) sensorimotor processing as well as general cortical excitability. These observations converge to implicate thalamocortical connectivity as a potential unifying neural mechanism. The goal of this study was to clarify mixed findings on thalamocortical functional connectivity in a large sample of individuals with ASD. Using the Autism Brain Imaging Data Exchange (ABIDE), we examined thalamocortical functional connectivity in 228 individuals with ASD and a matched comparison group of 228 typically developing

Biological psychiatry. Cognitive neuroscience and neuroimaging2017 Full Text: Link to full Text with Trip Pro

45. Network organization is globally atypical in autism: A graph theory study of intrinsic functional connectivity

Network organization is globally atypical in autism: A graph theory study of intrinsic functional connectivity 28944305 2018 11 13 2451-9030 2 1 2017 Jan Biological psychiatry. Cognitive neuroscience and neuroimaging Biol Psychiatry Cogn Neurosci Neuroimaging Network organization is globally atypical in autism: A graph theory study of intrinsic functional connectivity. 66-75 10.1016/j.bpsc.2016.07.008 Despite abundant evidence of brain network anomalies in autism spectrum disorder (ASD (...) Development Imaging Laboratory, Department of Psychology, San Diego State University, San Diego, CA, United States. eng R01 MH081023 MH NIMH NIH HHS United States R25 GM058906 GM NIGMS NIH HHS United States Journal Article United States Biol Psychiatry Cogn Neurosci Neuroimaging 101671285 2451-9022 Autism Spectrum Disorder Brain networks Community structure Graph theory Intrinsic functional connectivity Rich club 2017 9 26 6 0 2017 9 26 6 0 2017 9 26 6 1 ppublish 28944305 10.1016/j.bpsc.2016.07.008

Biological psychiatry. Cognitive neuroscience and neuroimaging2017 Full Text: Link to full Text with Trip Pro

46. Biomedical treatment for autism spectrum disorders

Biomedical treatment for autism spectrum disorders Biomedical treatment for autism spectrum disorders Biomedical treatment for autism spectrum disorders Mengarelli C, García Martí S, Pichon-Riviere A, Augustovski F, Alcaraz A, Bardach A, Ciapponi A, López A, Rey-Ares L Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mengarelli C, García (...) Martí S, Pichon-Riviere A, Augustovski F, Alcaraz A, Bardach A, Ciapponi A, López A, Rey-Ares L. Biomedical treatment for autism spectrum disorders. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No. 504. 2016 Authors' conclusions No randomized clinical trials having assessed the use of biomedical treatment (defined as a heterogeneous subgroup of alternative therapies such as vitamin supplements, special diets, digestive enzymes, etc

Health Technology Assessment (HTA) Database.2016

47. Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis

Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis 27873285 2018 11 13 2199-1154 3 4 2016 Dec Drugs - real world outcomes Drugs Real World Outcomes Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis. 409-425 A lack of gold standard treatment for autism spectrum disorders (ASD), no clear ASD management guidelines, and lack of evidence (...) Virginia University, Morgantown, WV, 26506 9510, USA. Autism/TRAIN, Center for Excellence in Disabilities (CED), Morgantown, WV, USA. Dwibedi Nilanjana N Department of Pharmaceutical Systems and Policy, West Virginia University, 1 Medical Center Drive, Morgantown, WV, 26506 9510, USA. Ajmera Mayank M RTI Health Solutions, Research Triangle Park, NC, USA. eng U54 GM104942 GM NIGMS NIH HHS United States Journal Article Switzerland Drugs Real World Outcomes 101658456 2198-9788 Child Adolesc Psychiatry

Drugs - real world outcomes2016 Full Text: Link to full Text with Trip Pro

48. "We Dance and Find Each Other"1: Effects of Dance/Movement Therapy on Negative Symptoms in Autism Spectrum Disorder.

"We Dance and Find Each Other"1: Effects of Dance/Movement Therapy on Negative Symptoms in Autism Spectrum Disorder. 27834905 2016 11 11 2017 02 24 6 4 2016 Nov 10 Behavioral sciences (Basel, Switzerland) Behav Sci (Basel) "We Dance and Find Each Other"1: Effects of Dance/Movement Therapy on Negative Symptoms in Autism Spectrum Disorder. E24 The treatment of deficits in social interaction, a shared symptom cluster in persons with schizophrenia (negative symptoms) and autism spectrum disorder (...) (DSM-5 A-criterion), has so far remained widely unsuccessful in common approaches of psychotherapy. The alternative approach of embodiment brings to focus body-oriented intervention methods based on a theoretic framework that explains the disorders on a more basic level than common theory of mind approaches. The randomized controlled trial at hand investigated the effects of a 10-week manualized dance and movement therapy intervention on negative symptoms in participants with autism spectrum

Behavioral sciences (Basel, Switzerland)2016 Full Text: Link to full Text with Trip Pro

49. Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm

Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm 27592094 2016 09 04 2017 04 12 1097-6833 178 2016 Nov The Journal of pediatrics J. Pediatr. Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm. 101-107.e2 S0022-3476(16)30654-0 10.1016/j.jpeds.2016.07.052 To examine the predictive validity of the Modified Checklist for Autism in Toddlers (M-CHAT) administered at age 24 months for autism spectrum disorder (...) ):37-45 24366990 J Pediatr. 2010 Apr;156(4):525-31.e2 20056232 J Child Psychol Psychiatry. 2015 Sep;56(9):988-98 25921776 J Autism Dev Disord. 2001 Apr;31(2):131-44 11450812 Autism Res. 2016 May 25;: 27220677 J Autism Dev Disord. 2013 Oct;43(10):2269-79 23386118 Paediatr Perinat Epidemiol. 2014 May;28(3):255-62 24547686 Natl Health Stat Report. 2015 Nov 13;(87):1-20 26632847 J Autism Dev Disord. 2015 Jun;45(6):1797-808 25488122 Pediatrics. 2016 Feb;137(2):e20151949 26798043 Pediatrics. 2011 Nov;128

EvidenceUpdates2016

50. Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial.

Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial. BACKGROUND: It is not known whether early intervention can improve long-term autism symptom outcomes. We aimed to follow-up the Preschool Autism Communication Trial (PACT), to investigate whether the PACT intervention had a long-term effect on autism symptoms and continued effects on parent and child social interaction. METHODS: PACT was a randomised (...) controlled trial of a parent-mediated social communication intervention for children aged 2-4 years with core autism. Follow-up ascertainment was done at three specialised clinical services centres in the UK (London, Manchester, and Newcastle) at a median of 5·75 years (IQR 5·42-5·92) from the original trial endpoint. The main blinded outcomes were the comparative severity score (CSS) from the Autism Diagnostic Observation Schedule (ADOS), the Dyadic Communication Assessment Measure (DCMA

Lancet2016

51. Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD).

Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD). BACKGROUND: The rising prevalence of autism spectrum disorder (ASD) has increased the need for evidence-based treatments to lessen the impact of symptoms. Presently, no therapies are available to effectively treat individuals with all of the symptoms of this disorder. It has been suggested that hyperbaric oxygen therapy may alleviate the biochemical dysfunction and clinical symptoms of ASD. OBJECTIVES: To determine

Cochrane2016

52. Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders

Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders 27454803 2016 09 07 2017 02 24 2168-6211 170 9 2016 Sep 06 JAMA pediatrics JAMA Pediatr Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders. e160965 10.1001/jamapediatrics.2016.0965 Induction of labor is a frequently performed obstetrical intervention. It would thus be of great concern if reported associations between labor induction and offspring risk of autism spectrum disorders (ASD (...) of labor. Autism spectrum disorders identified by diagnoses from inpatient and outpatient records between 2001 and 2013. Hazard ratios (HRs) quantified the association between labor induction and offspring ASD. In addition to considering a wide range of measured confounders, comparison of exposure-discordant births to the same woman allowed additional control for all unmeasured factors shared by siblings. The full cohort included 1 362 950 births, of which 22 077 offspring (1.6%) were diagnosed

EvidenceUpdates2016

53. Genome-wide characteristics of de novo mutations in autism

Genome-wide characteristics of de novo mutations in autism 27525107 2018 11 13 2056-7944 1 2016 Aug 03 NPJ genomic medicine NPJ Genom Med Genome-wide characteristics of de novo mutations in autism. 160271-1602710 De novo mutations (DNMs) are important in Autism Spectrum Disorder (ASD), but so far analyses have mainly been on the ~1.5% of the genome encoding genes. Here, we performed whole genome sequencing (WGS) of 200 ASD parent-child trios and characterized germline and somatic DNMs. We (...) -Shenzhen, Yantian, Shenzhen, China. Li Yingrui Y BGI-Shenzhen, Yantian, Shenzhen, China. Wang Jun J BGI-Shenzhen, Yantian, Shenzhen, China. Wang Jian J BGI-Shenzhen, Yantian, Shenzhen, China. Yang Huanming H BGI-Shenzhen, Yantian, Shenzhen, China. Bookman Matt M Google, Mountain View, California, USA. Bingham Jonathan J Google, Mountain View, California, USA. Gross Samuel S SS Google, Mountain View, California, USA. Loy Dion D Google, Mountain View, California, USA. Pletcher Mathew M Autism Speaks

NPJ genomic medicine2016 Full Text: Link to full Text with Trip Pro

54. Assessment, diagnosis and interventions for autism spectrum disorders

Assessment, diagnosis and interventions for autism spectrum disorders

SIGN2016

55. A microcosting and cost-consequence analysis of genomic testing strategies in autism spectrum disorder

A microcosting and cost-consequence analysis of genomic testing strategies in autism spectrum disorder A microcosting and cost-consequence analysis of genomic testing strategies in autism spectrum disorder A microcosting and cost-consequence analysis of genomic testing strategies in autism spectrum disorder Tsiplova K, Zur RM, Ungar WJ Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment (...) has been made for the HTA database. Citation Tsiplova K, Zur RM, Ungar WJ. A microcosting and cost-consequence analysis of genomic testing strategies in autism spectrum disorder. Toronto, ON: Technology Assessment at SickKids (TASK). 2016 Authors' conclusions This study is the first to estimate the cost of clinical exome and genome sequencing using a bottom-up microcosting approach, The WGS using older technology (HiSeq 2500) was the most expensive test, costing almost three times as much as WES

Health Technology Assessment (HTA) Database.2016

56. Association of Psychiatric and Neurologic Comorbidity With Mortality Among Persons With Autism Spectrum Disorder in a Danish Population

Association of Psychiatric and Neurologic Comorbidity With Mortality Among Persons With Autism Spectrum Disorder in a Danish Population 26752506 2016 03 08 2016 08 01 2016 03 08 2168-6211 170 3 2016 Mar JAMA pediatrics JAMA Pediatr Association of Psychiatric and Neurologic Comorbidity With Mortality Among Persons With Autism Spectrum Disorder in a Danish Population. 243-50 10.1001/jamapediatrics.2015.3935 Increased mortality has been reported among persons with autism spectrum disorder (ASD (...) AIM IM Adolescent Autism Spectrum Disorder epidemiology mortality Child Child, Preschool Comorbidity Denmark epidemiology Female Humans Infant Longitudinal Studies Male Mental Disorders epidemiology Nervous System Diseases epidemiology Prospective Studies Young Adult 2016 1 12 6 0 2016 1 12 6 0 2016 8 2 6 0 ppublish 26752506 2479467 10.1001/jamapediatrics.2015.3935

EvidenceUpdates2016

57. Screening for Autism Spectrum Disorder in Young Children: US Preventive Services Task Force Recommendation Statement.

Screening for Autism Spectrum Disorder in Young Children: US Preventive Services Task Force Recommendation Statement. DESCRIPTION: New US Preventive Services Task Force (USPSTF) recommendation on screening for autism spectrum disorder (ASD) in young children. METHODS: The USPSTF reviewed the evidence on the accuracy, benefits, and potential harms of brief, formal screening instruments for ASD administered during routine primary care visits and the benefits and potential harms of early

JAMA2016

58. Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial wi

Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial wi Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised

NIHR HTA programme2016

59. Diagnosing autism spectrum disorder (ASD) among adults

Diagnosing autism spectrum disorder (ASD) among adults Diagnosing autism spectrum disorder (ASD) among adults | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Diagnosing autism spectrum disorder (ASD) among adults Article Text Evidence-based case conference Diagnosing autism spectrum disorder (ASD) among adults Toshi A Furukawa Statistics from Altmetric.com No Altmetric data available for this article. Clinical case Patient: 18-year-old man Present illness : The patient was brought to your department of psychiatry by his worried mother. While

Evidence-Based Mental Health2016

60. Autism Spectrum Disorder in Young Children: Screening

Autism Spectrum Disorder in Young Children: Screening Final Update Summary: Autism Spectrum Disorder in Young Children: Screening - US Preventive Services Task Force Search USPSTF Website Text size: Assembly version: 1.0.0.308 Last Build: 3/6/2018 4:20:40 PM You are here: Final Summary To watch a video about this final recommendation and learn more, click . Autism Spectrum Disorder in Young Children: Screening Release Date: February 2016 Recommendation Summary Population Recommendation Grade (...) Children aged 18 to 30 months The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for autism spectrum disorder (ASD) in young children for whom no concerns of ASD have been raised by their parents or a clinician. See the for suggestions for practice regarding the I statement. To read the recommendation statement in JAMA , click . ( ) Related Information for Consumers Related Information for Health Professionals There is no related

U.S. Preventive Services Task Force2016