Latest & greatest articles for autism

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on autism or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on autism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

221. Parent implemented early intervention for young children with autism spectrum disorder: a systematic review

Parent implemented early intervention for young children with autism spectrum disorder: a systematic review Parent implemented early intervention for young children with autism spectrum disorder: a systematic review Parent implemented early intervention for young children with autism spectrum disorder: a systematic review McConachie H, Diggle T CRD summary This review investigated the effectiveness of parent-implemented early intervention for young children with autism spectrum disorder (...) . The authors concluded that parent training can successfully contribute to early intervention, though better quality research is required. While the authors' conclusions seem reasonable, it needs to be kept in mind that there is also contradictory evidence about parent training programmes. Authors' objectives To investigate the effectiveness of parent-implemented early intervention for young children with autism spectrum disorder (ASD). Searching MEDLINE, EMBASE, PsycINFO, CINAHL, ERIC, the Cochrane

DARE.2007

222. A review of interventions to reduce challenging behavior in school settings for students with autism spectrum disorders

A review of interventions to reduce challenging behavior in school settings for students with autism spectrum disorders A review of interventions to reduce challenging behavior in school settings for students with autism spectrum disorders A review of interventions to reduce challenging behavior in school settings for students with autism spectrum disorders Machalicek W, O'Reilly M F, Beretvas N, Sigafoos J, Lancioni G E CRD summary The review concluded that the interventions effectively (...) decreased or eliminated various challenging behaviours for school students with autism spectrum disorders across different age groups. Poor reporting of review methods, the lack of an assessment of validity, and small sample sizes mean that the authors' conclusions may not be reliable. Authors' objectives To evaluate interventions for the treatment of challenging behaviour for students with autism spectrum disorders (ASD) in school settings. Searching ERIC, PsycINFO and MEDLINE were searched; the search

DARE.2007

223. Effects and implications of self-management for students with autism: a meta-analysis

Effects and implications of self-management for students with autism: a meta-analysis Effects and implications of self-management for students with autism: a meta-analysis Effects and implications of self-management for students with autism: a meta-analysis Lee S H, Simpson R L, Shogren K A CRD summary This review assessed self-management techniques for increasing appropriate behaviours in children with autism. The authors concluded that such techniques were effective. However, the review (...) was poorly reported and used a questionable approach to synthesis, which means that the conclusions cannot be regarded as reliable. Authors' objectives To assess the efficacy of self-management in increasing appropriate behaviour in children and young people with autism. Searching PsycINFO, ERIC and Wilson OmniFile were searched for studies published prior to October 2004; the search terms were reported. The references of retrieved articles were checked, and review articles and book chapters were also

DARE.2007

224. The role of hyperbaric oxygen therapy in the management of autism

The role of hyperbaric oxygen therapy in the management of autism The role of hyperbaric oxygen therapy in the management of autism The role of hyperbaric oxygen therapy in the management of autism Agence d'Evaluation des Technologies et des Modes d'Intervention en Sante Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Agence d'Evaluation (...) des Technologies et des Modes d'Intervention en Sante. The role of hyperbaric oxygen therapy in the management of autism. Montreal: Agence d'evaluation des technologies et des modes d'intervention en sante (AETMIS). AETMIS 07-11. 2007 Authors' conclusions Upon the completion of this systematic literature review, we observe that this is a topic of recent interest. The scientifi c data available at this time are of low quality, and the level of evidence does not enable one to build a strong case

Health Technology Assessment (HTA) Database.2007

225. Hyperbaric oxygen therapy for autism

Hyperbaric oxygen therapy for autism Hyperbaric oxygen therapy for autism Hyperbaric oxygen therapy for autism Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Hyperbaric oxygen therapy for autism. Lansdale: HAYES, Inc.. Directory Publication. 2007 Authors' objectives Hyperbaric oxygen therapy (HBOT), in which patients breathe 28% to 30% oxygen at elevated (...) pressure, typically at 1.3 to 1.5 atmospheric absolute, has been investigated as a treatment for autism. The goal of the therapy is to improve behavioral symptoms of autism by increasing oxygenation of the brain through a combination of increased hydrostatic pressure and elevation of the tissue oxygen tension. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Autistic Disorder /therapy; Hyperbaric Oxygenation Language Published English Country of organisation United States Address

Health Technology Assessment (HTA) Database.2007

226. Floor time therapy in autism

Floor time therapy in autism Floor time therapy in autism Floor time therapy in autism Pichon Riviere A, Augustovski F, Alcaraz A, Bardach A, Ferrante D, Garcia Marti S, Glujovsky D, Lopez A, Regueiro A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Alcaraz A, Bardach A, Ferrante D, Garcia Marti S (...) , Glujovsky D, Lopez A, Regueiro A. Floor time therapy in autism. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe Tecnico Breve No.31. 2007 Authors' objectives The objective of the report was to assess the evidence available on the usefulness of Floor Time therapy in autism. Authors' conclusions In general, the quality of the studies associated with educational treatment programs for autistic children are methodologically poor and Floor Time therapy is not an exception

Health Technology Assessment (HTA) Database.2007

227. Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children

Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children Article Text Aetiology Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children Free Joachim

Evidence-Based Medicine (Requires free registration)2006

228. The Screening Tool for Autism in Two Year Olds can identify children at risk of autism

The Screening Tool for Autism in Two Year Olds can identify children at risk of autism The Screening Tool for Autism in Two Year Olds can identify children at risk of autism | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The Screening Tool for Autism in Two Year Olds can identify children at risk of autism Article Text Diagnosis The Screening Tool for Autism in Two Year Olds can identify children at risk of autism Free Lonnie Zwaigenbaum , MD, MSc Statistics from Altmetric.com No Altmetric data available for this article. Stone WL, Coonrod EE

Evidence-Based Mental Health2006

229. Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP).

Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). BACKGROUND: Recent reports have suggested that the prevalence of autism and related spectrum disorders (ASDs) is substantially higher than previously recognised. We sought to quantify prevalence of ASDs in children in South Thames, UK. METHODS: Within a total population cohort of 56 946 children aged 9-10 years, we screened all those with a current (...) clinical diagnosis of ASD (n=255) or those judged to be at risk for being an undetected case (n=1515). A stratified subsample (n=255) received a comprehensive diagnostic assessment, including standardised clinical observation, and parent interview assessments of autistic symptoms, language, and intelligence quotient (IQ). Clinical consensus diagnoses of childhood autism and other ASDs were derived. We used a sample weighting procedure to estimate prevalence. FINDINGS: The prevalence of childhood autism

Lancet2006

230. Screening for autism in pre-school children in primary care: systematic review of English language tools

Screening for autism in pre-school children in primary care: systematic review of English language tools Screening for autism in pre-school children in primary care: systematic review of English language tools Screening for autism in pre-school children in primary care: systematic review of English language tools Mawle E, Griffiths P CRD summary This review found that the Checklist for Autism in Toddlers (CHAT) was unlikely to offer sufficient sensitivity to be useful for population screening (...) ; the modified CHAT appears more promising but further research was required. These conclusions should be interpreted with caution given the likelihood that relevant studies have been missed, the failure to appropriately consider study quality, and the poor quality and small number of included studies. Authors' objectives To determine the accuracy of brief screening tools for autism in pre-school children. Searching MEDLINE, CINAHL, EMBASE and PsycINFO were searched from inception to January 2005. The full

DARE.2006

231. There is preliminary evidence that LEGO therapy can improve social skills in children with Autism Spectrum Disorder

There is preliminary evidence that LEGO therapy can improve social skills in children with Autism Spectrum Disorder

Occupational Therapy CATs2006

232. Combined vitamin B6-magnesium treatment in autism spectrum disorder.

Combined vitamin B6-magnesium treatment in autism spectrum disorder. BACKGROUND: The use of mega-vitamin intervention began in the 1950s with the treatment of schizophrenic patients. Pyroxidine (vitamin B6) was first used with children diagnosed with "autism syndrome" when speech and language improvement was observed in some children as a result of large doses of B6. A number of studies attempted to assess the effects of vitamin B6-Magnesium (Mg) was found to reduce undesirable side effects (...) from B6) on characteristics such as verbal communication, non-verbal communication, interpersonal skills, and physiological function, in individuals with autism. OBJECTIVES: To determine the efficacy of vitamin B6 and magnesium (B6-Mg) for treating social, communication, and behavioural responses of children and adults with autism. SEARCH STRATEGY: We searched the Cochrane Controlled Trials Register (Cochrane Library, Issue 2, 2002), MEDLINE (1966 to January 2002), EMBASE (1980 to January 2002

Cochrane2005

233. There is preliminary evidence (level 4) that social stories are effective in decreasing challenging behaviours and may improve social interaction skills in children with Autism Spectrum Disorders

There is preliminary evidence (level 4) that social stories are effective in decreasing challenging behaviours and may improve social interaction skills in children with Autism Spectrum Disorders

Occupational Therapy CATs2005

234. Review: existing epidemiological evidence does not show an association between mumps, measles, and rubella vaccination and autism

Review: existing epidemiological evidence does not show an association between mumps, measles, and rubella vaccination and autism Review: existing epidemiological evidence does not show an association between mumps, measles, and rubella vaccination and autism | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in via your Society Log in using your username and password For personal accounts OR managers of institutional (...) accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: existing epidemiological evidence does not show an association between mumps, measles, and rubella vaccination and autism Article Text Causation Review: existing epidemiological evidence does

Evidence-Based Nursing (Requires free registration)2005

235. About 3 in every 1000 US children in large metropolitan areas may have autism or related developmental disorders

About 3 in every 1000 US children in large metropolitan areas may have autism or related developmental disorders About 3 in every 1000 US children in large metropolitan areas may have autism or related developmental disorders | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here About 3 in every 1000 US children in large metropolitan areas may have autism or related developmental disorders Article Text Prevalence About 3 in every 1000 US children in large metropolitan areas may have autism or related developmental disorders Free Susan E Bryson , PhD

Evidence-Based Mental Health2004

236. Measles, mumps, and rubella vaccine was not associated with autism in children

Measles, mumps, and rubella vaccine was not associated with autism in children Measles, mumps, and rubella vaccine was not associated with autism in children | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Measles, mumps, and rubella vaccine was not associated with autism in children Article Text Causation Measles, mumps, and rubella vaccine was not associated with autism in children Free Stephanie Wright , CFNP, CPNP, PhD Statistics from Altmetric.com No Altmetric data available for this article

Evidence-Based Nursing (Requires free registration)2004

237. Secretin as a treatment for autism: a review of the evidence

Secretin as a treatment for autism: a review of the evidence Secretin as a treatment for autism: a review of the evidence Secretin as a treatment for autism: a review of the evidence Esch B E, Carr J E CRD summary This review assessed the effectiveness of secretin as a treatment for autism. The authors appear to conclude that secretin is no better than placebo at providing symptomatic relief of autism. Although this conclusion reflects the evidence presented, the reliability of the review may (...) be limited by its methodological weaknesses. Authors' objectives To assess the effectiveness of secretin as a treatment for autism. Searching PsycINFO and MEDLINE were searched from 1986 to 2002 using the reported search terms. Study selection Study designs of evaluations included in the review There were no specific inclusion criteria for the study design. Most of the included studies were randomised controlled trials (RCTs), although there were also uncontrolled studies and case series. The duration

DARE.2004

238. A research synthesis of social story interventions for children with autism spectrum disorders

A research synthesis of social story interventions for children with autism spectrum disorders A research synthesis of Social Story interventions for children with autism spectrum disorders A research synthesis of Social Story interventions for children with autism spectrum disorders Sansosti F J, Powell-Smith K A, Kincaid D CRD summary This review attempted to assess the effectiveness of social stories for educating children with autism spectrum disorders. The authors concluded that current (...) evidence supports the use of social story interventions for children with autism spectrum disorders. Poorly defined inclusion criteria, a limited search strategy and a small evidence base limit the reliability of these findings. Authors' objectives To determine the effectiveness of social stories for educating children with autism spectrum disorders (ASDs). Searching PsycINFO and ERIC were searched for relevant papers; the search dates and search terms were not reported. Study selection Study designs

DARE.2004

239. Music in intervention for children and adolescents with autism: a meta-analysis

Music in intervention for children and adolescents with autism: a meta-analysis Music in intervention for children and adolescents with autism: a meta-analysis Music in intervention for children and adolescents with autism: a meta-analysis Whipple J CRD summary The author of this review concluded that all music interventions for children and adolescents with autism were effective, but further research is required. The poor reporting of review methods, lack of a validity assessment, evidence (...) from a small number of diverse studies and limitations in the analysis make the reliability of the conclusions about effectiveness uncertain. Authors' objectives To examine the effects of music as an intervention for children and adolescents with autism. Searching Three relevant journals and an online database of dissertations and theses were searched using 'music' and 'autism' or 'autistic' as the keywords. Full papers were obtained from the American Music Therapy Association from 2002

DARE.2004