Latest & greatest articles for asthma

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Top results for asthma

1201. A comparison of the cost effectiveness of alternative prophylactic therapies in childhood asthma

A comparison of the cost effectiveness of alternative prophylactic therapies in childhood asthma A comparison of the cost effectiveness of alternative prophylactic therapies in childhood asthma A comparison of the cost effectiveness of alternative prophylactic therapies in childhood asthma Booth P C, Wells N E, Morrison A K Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Prophylactic treatment of asthma in childhood by fluticasone versus sodium cromoglycate. Type of intervention Secondary prevention. Economic study type Cost-effectiveness analysis. Study population Patients were aged between 4 and 12 years, had a clinical history of asthma, and were already receiving bronchodilator therapy. 305 children were recruited

NHS Economic Evaluation Database.1996

1202. Theophylline in acute childhood asthma: a meta-analysis of its efficacy

Theophylline in acute childhood asthma: a meta-analysis of its efficacy Theophylline in acute childhood asthma: a meta-analysis of its efficacy Theophylline in acute childhood asthma: a meta-analysis of its efficacy Goodman D C, Littenberg B, O'Connor G T, Brooks J G Authors' objectives To determine the efficacy of theophylline in children hospitalised with acute asthma. Searching MEDLINE was searched from 1966 to May 1994; details of the search strategy were given. Study selection Study (...) designs of evaluations included in the review Randomised controlled trials (RCTs) with study durations ranging from 24 to 36 hours, and until discharge, were included. Specific interventions included in the review IV Aminophylline or IV theophylline in the context of standard therapy for asthma, i.e. the treatment groups also received other bronchodilators and steroids, while the comparison groups received the same standard therapy, with the omission of theophylline. Participants included

DARE.1996

1203. Economic analysis of two structured treatment and teaching programs on asthma

Economic analysis of two structured treatment and teaching programs on asthma Economic analysis of two structured treatment and teaching programs on asthma Economic analysis of two structured treatment and teaching programs on asthma Neri M, Migliori G B, Spanevello A, Berra D, Nicolin E, Landoni C V, Ballardini L, Sommaruga M, Zanon P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Using a complete (CP) versus reduced (RP) educational programme on asthma to reduce the asthma-induced incidents in asthma patients. The CP group received six lessons based on an educational booklet and educational videotapes, while the RP group had only a self-reading of the same educational booklet. The patients in both programmes received peak

NHS Economic Evaluation Database.1996

1204. Efficacy and cost benefit of inhaled corticosteroids in patients considered to have mild asthma in primary care practice

Efficacy and cost benefit of inhaled corticosteroids in patients considered to have mild asthma in primary care practice Efficacy and cost benefit of inhaled corticosteroids in patients considered to have mild asthma in primary care practice Efficacy and cost benefit of inhaled corticosteroids in patients considered to have mild asthma in primary care practice O'Byrne P, Cuddy L, Taylor D W, Birch S, Morris J, Syrotuik J Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Inhaled corticosteroids (budesonide) for the prevention of asthmatic attacks and the reduction of associated symptoms. Type of intervention Secondary prevention and treatment. Economic study type Cost-benefit analysis. Study population Adults aged 18 years

NHS Economic Evaluation Database.1996

1205. [Cost-effectiveness studies of ambulatory educational programs for children with asthma and their families]

[Cost-effectiveness studies of ambulatory educational programs for children with asthma and their families] Kosten-Nutzen-Untersuchungen bei ambulanten Schulungsmassnahmen fur asthmakranke Kinder und ihre Familien [Cost-effectiveness studies of ambulatory educational programs for children with asthma and their families] Kosten-Nutzen-Untersuchungen bei ambulanten Schulungsmassnahmen fur asthmakranke Kinder und ihre Familien [Cost-effectiveness studies of ambulatory educational programs (...) for children with asthma and their families] Scholtz W, Haubrock M, Lob-Corzilius T, Gebert N, Wahn U, Szczepanski R Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Training programmes for asthmatic children. Type of intervention

NHS Economic Evaluation Database.1996

1206. Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial.

Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club1996

1207. Randomised comparison of guided self management and traditional treatment of asthma over one year.

Randomised comparison of guided self management and traditional treatment of asthma over one year. 8605463 1996 05 23 1996 05 23 2013 11 21 0959-8138 312 7033 1996 Mar 23 BMJ (Clinical research ed.) BMJ Randomised comparison of guided self management and traditional treatment of asthma over one year. 748-52 To compare the efficacy of self management of asthma with traditional treatment. 12 month prospective randomised trial. Outpatient clinics in Finland. 115 patients with mild to moderately (...) severe asthma. Patient education and adjustment of anti-inflammatory therapy guided by peak flow measurements. Unscheduled admissions to hospital and outpatient visits, days off work, courses of antibiotics and prednisolone, lung function, and quality of life. The mean number of unscheduled visits to ambulatory care facilities (0.5 v 1.0), days off work (2.8 v 4.8), and courses of antibiotics (0.4 v 0.9) and prednisolone (0.4 v 1.0) per patient were lower and the quality of life score (16.6 v 8.4

BMJ1996 Full Text: Link to full Text with Trip Pro

1208. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group.

Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group. 8598621 1996 04 23 1996 04 23 2016 11 23 0098-7484 275 12 1996 Mar 27 JAMA JAMA Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group. 931-6 To study the effect of 3 months of treatment with zileuton, an inhibitor of the enzymatic pathway (5-lipoxygenase (...) ) leading to leukotriene formation, on disease control in patients with mild to moderate asthma. Randomized, double-blind, parallel-group study in 401 patients. A 10-day placebo lead-in was followed by a double-blind treatment period of 13 weeks. Asthma study clinics in university hospitals and private practices. Patients with mild to moderate asthma (forced expiratory volume in the first second [FEV1], 40% to 80% of predicted) whose only treatment was inhaled beta-agonists. Treatment with 600 mg or 400

JAMA1996

1209. Ragweed immunotherapy in adult asthma.

Ragweed immunotherapy in adult asthma. 8559203 1996 02 23 1996 02 23 2010 03 24 0028-4793 334 8 1996 Feb 22 The New England journal of medicine N. Engl. J. Med. Ragweed immunotherapy in adult asthma. 501-6 Although allergen immunotherapy is effective for allergic rhinitis, its role in treating asthma is unclear. We examined the efficacy of immunotherapy for asthma exacerbated by seasonal ragweed exposure. During an observation phase, adults with asthma who were sensitive to ragweed kept daily (...) diaries and recorded peak expiratory flow rates between July and October. Those who reported seasonal asthma symptoms and medication use as well as decreased peak expiratory flow were randomly assigned to receive placebo or ragweed-extract immunotherapy in doses that increased weekly for an additional two years. During the observation phase, the mean (+/- SE) peak expiratory flow rate measured in the morning during the three weeks representing the height of the pollination season was 454 +/- 20 liters

NEJM1996

1210. Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma.

Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma. 8709736 1996 09 06 1996 09 06 2015 11 19 0140-6736 348 9024 1996 Aug 10 Lancet (London, England) Lancet Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma. 374-7 Bronchoconstriction induced by bradykinin is reduced by the release of nitric oxide (NO) in the airways of guinea pigs (...) . Inhaled NO is known to cause bronchodilatation in asthmatic patients. To find out the role of endogenous NO in airway response to bradykinin in asthma, we examined the effect of the NO synthase inhibitor NG-monomethyl-L-arginine (L-NMMA) on broncho-constriction after bradykinin challenge in ten patients with mild asthma. The study had a randomised, double-blind, placebo-controlled, cross-over design. Participants were studied during two phases, each consisting of 2 study days. After baseline

Lancet1996

1211. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network.

Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. 8778601 1996 09 19 1996 09 19 2013 11 21 0028-4793 335 12 1996 Sep 19 The New England journal of medicine N. Engl. J. Med. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. 841-7 Inhaled beta-agonists are the most commonly used treatment for asthma, but data suggest that regularly scheduled use of these agents may (...) have deleterious effect on the control of asthma. We compared the effects of regularly scheduled use of inhaled albuterol with those of albuterol used only as needed in patients with mild chronic, stable asthma. In a multicenter, double-blind study, we randomly assigned 255 patients with mild asthma to inhale albuterol either on a regular schedule (126 patients) or only as needed (129 patients). The patients were followed for 16 weeks. The primary outcome indicator, peak expiratory air flow

NEJM1996

1212. Is allergen immunotherapy effective in asthma: a meta-analysis of randomized controlled trials

Is allergen immunotherapy effective in asthma: a meta-analysis of randomized controlled trials Is allergen immunotherapy effective in asthma: a meta-analysis of randomized controlled trials Is allergen immunotherapy effective in asthma: a meta-analysis of randomized controlled trials Abramson M J, Puy R M, Weiner J M Authors' objectives To assess the efficacy of allergen immunotherapy in asthma. Searching MEDLINE was searched from 1966 to 1990 using the keywords 'allergen immunotherapy (...) ', 'desensitization' and 'asthma'. Dissertation Abstracts was also searched, and reference lists of review papers on allergen immunotherapy and text books were examined. Only trials published in the English language were included. Study selection Study designs of evaluations included in the review Double-blind, randomised, placebo-controlled trials were included. Specific interventions included in the review Allergen immunotherapy. Participants included in the review Asthma patients were included. Outcomes

DARE.1995

1213. Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice

Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice Bryce F P, Neville R G, Crombie I K, Clark R A, McKenzie P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of an audit facilitator in the diagnosis and treatment of childhood asthma in general practice. Type of intervention Secondary prevention. Economic study type Cost-effectiveness analysis. Study population Children of both sexes aged between 1 and 15 inclusive, with symptoms suggestive

NHS Economic Evaluation Database.1995

1214. Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis

Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis Osmond M H, Klassen T P Authors' objectives To establish if ipratropium bromide, when given in conjunction with beta2-agonists, is beneficial to the health of children suffering with acute asthma. Searching MEDLINE was searched from 1966 to 1992 for articles published (...) in the English language using the following MeSH terms: 'N-isopropylatropine' and (explode) 'child', and 'asthma' and (explode) 'child'. The reference lists of all available primary and review articles were searched for relevant literature, and the two oldest studies included were searched forward in time using the Science Citation Index. The authors of all the selected studies were contacted for additional material. Study selection Study designs of evaluations included in the review Randomised, double-blind

DARE.1995

1215. Self-management teaching programs and morbidity of pediatric asthma: a meta-analysis

Self-management teaching programs and morbidity of pediatric asthma: a meta-analysis Self-management teaching programs and morbidity of pediatric asthma: a meta-analysis Self-management teaching programs and morbidity of pediatric asthma: a meta-analysis Bernard-Bonnin A C, Stachenko S, Bonin D, Charette C, Rousseau E Authors' objectives To assess the impact of self-management teaching programmes on the morbidity of paediatric asthma. Searching MEDLINE, Index Medicus, American Journal (...) of Nursing International Index, Dissertation Abstracts Online Database and the bibliographies of retrieved articles were searched. Authors of preliminary or pilot studies were contacted. Only English or French literature published between 1970 and 1991 were searched with the keywords 'asthma', 'education' and 'self-management programs'. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were included. Specific interventions included in the review Self

DARE.1995

1216. Protocol therapy for acute asthma: therapeutic benefits and cost savings

Protocol therapy for acute asthma: therapeutic benefits and cost savings Protocol therapy for acute asthma: therapeutic benefits and cost savings Protocol therapy for acute asthma: therapeutic benefits and cost savings McFadden E R, Elsanadi N, Dixon L, Takacs M, Deal E C, Boyd K K, Idemoto B K, Broseman L A, Panuska J, Hammons T, Smith B, Caruso F, McFadden C B, Shoemaker L, Warren E L, Hejal R, Strauss L, Gilbert I A Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Protocol therapy for acute episodes of asthma, treated in an emergency department. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population Asthmatic patients aged 16 years or older, presenting to the emergency

NHS Economic Evaluation Database.1995

1217. A self-management program for adult asthma. Part II: cost-benefit analysis

A self-management program for adult asthma. Part II: cost-benefit analysis A self-management program for adult asthma. Part II: cost-benefit analysis A self-management program for adult asthma. Part II: cost-benefit analysis Taitel M S, Kotses H, Bernstein I L, Bernstein D I, Creer T L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology An educational training programme for self-management of adult asthma. Type of intervention Educational intervention; Secondary prevention; Patient management. Economic study type Cost-effectiveness analysis. Study population Adult patients with moderate to severe asthma as described by themselves. In all cases, asthma had been adequately controlled by medical treatment. Patients were excluded from

NHS Economic Evaluation Database.1995

1218. Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis

Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club1995

1219. Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice.

Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice. 7711623 1995 05 17 1995 05 17 2015 11 19 0959-8138 310 6983 1995 Apr 01 BMJ (Clinical research ed.) BMJ Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice. 838-42 To test whether an audit facilitator could alter the pattern of diagnosis and treatment of childhood asthma. Randomised stratified controlled trial. 12 general practices (...) in Tayside. 3373 children aged 1-15 inclusive who had symptoms suggestive of asthma or possible asthma drawn from a systematic review of 10,725 general practice case records. Children were targeted for a clinical review by their general practitioner or practice nurses. Asthma related consultations, prescriptions, hospital attendances, and health service costs 12 months before and after study. Compared with controls (n = 1563) the intervention group (n = 1585) had more practice initiated consultations

BMJ1995 Full Text: Link to full Text with Trip Pro

1220. Using information from asthma patients: a trial of information feedback in primary care.

Using information from asthma patients: a trial of information feedback in primary care. 7580666 1995 12 19 1995 12 19 2013 09 22 0959-8138 311 7012 1995 Oct 21 BMJ (Clinical research ed.) BMJ Using information from asthma patients: a trial of information feedback in primary care. 1065-9 To test the effects of feedback of information about patients' asthma to primary care teams. Patients' reports of morbidity, use of health services, and drug use on questionnaire was given to primary care teams (...) . Randomised controlled trial with general practices as the subject of the intervention was used to test effectiveness of supplying information. Primary care in district health authority, London. 23 general practices, each of which notified at least 20 asthmatic patients aged 15-60 years for each principal. Practices were randomly allocated to an invention group (receiving feedback of information on control of asthma) or a control group (no feedback). Information on cards inserted in patients' medical

BMJ1995 Full Text: Link to full Text with Trip Pro