Latest & greatest articles for asthma

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Top results for asthma

261. Pills vs. Puffers: Leukotriene receptor antagonists for childhood asthma

Pills vs. Puffers: Leukotriene receptor antagonists for childhood asthma Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,000 family physicians, family medicine residents and medical students in Alberta. Established over fifty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research (...) . www.acfp.ca January 18, 2016 Pills vs. Puffers: Leukotriene receptor antagonists for childhood asthma Clinical Question: Are leukotriene receptor antagonists (LTRAs) effective in pediatric asthma? Bottom-line: Using leukotriene receptor antagonists instead of inhaled corticosteroids as monotherapy will lead to one more exacerbation in every 21 patients. As add-on to inhaled corticosteroids, leukotriene receptor antagonists are inferior to long acting beta-agonists (LABAs), and show similar outcomes

Tools for Practice2016

262. Asthma and chronic obstructive pulmonary disease overlap syndrome: An update

Asthma and chronic obstructive pulmonary disease overlap syndrome: An update 27847903 2018 11 13 2450-131X 3 4 2015 Oct-Dec Journal of translational internal medicine J Transl Int Med Asthma and chronic obstructive pulmonary disease overlap syndrome: An update. 144-146 Lu Ming M Department of Respiratory Medicine, Peking University Third Hospital, Beijing 100191, China. Yao Wan-Zhen WZ Department of Respiratory Medicine, Peking University Third Hospital, Beijing 100191, China. eng Journal

Journal of translational internal medicine2015 Full Text: Link to full Text with Trip Pro

263. Environmental Microbial Exposure and Protection against Asthma.

Environmental Microbial Exposure and Protection against Asthma. Environmental Microbial Exposure and Protection against Asthma. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26699175 Format MeSH and Other (...) Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Dec 24;373(26):2576-8. doi: 10.1056/NEJMcibr1511291. Environmental Microbial Exposure and Protection against Asthma. , . PMID: 26699175 DOI: [Indexed for MEDLINE] MeSH terms Substances Full Text Sources Medical PubMed Commons 0 comments How to cite this comment: Supplemental Content Full text links

NEJM2015

264. Airway reactivity and sphingolipids—implications for childhood asthma

Airway reactivity and sphingolipids—implications for childhood asthma 26637347 2015 12 15 2018 11 13 2194-7791 2 1 2015 Dec Molecular and cellular pediatrics Mol Cell Pediatr Airway reactivity and sphingolipids-implications for childhood asthma. 13 10.1186/s40348-015-0025-3 Asthma is a clinically heterogeneous disorder, whose onset and progression results from a complex interplay between genetic susceptibility, allergens, and viral triggers. Sphingolipids and altered sphingolipid metabolism (...) have emerged as potential key contributors to the pathogenesis of asthma. Orosomucoid-like 3 gene (ORMDL3) and the asthma susceptibility locus 17q21 have been strongly and reproducibly linked to childhood asthma, but how this gene is functionally linked to asthma is incompletely understood. ORMDL proteins play an integral role in sphingolipid homeostasis and synthesis, and asthma-associated ORMDL3 polymorphisms have been associated with early viral respiratory infections and increased risk

Molecular and cellular pediatrics2015 Full Text: Link to full Text with Trip Pro

265. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations 26518090 2015 12 15 2016 04 26 2017 02 28 1097-6825 136 6 2015 Dec The Journal of allergy and clinical immunology J. Allergy Clin. Immunol. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. 1476-85 10.1016/j.jaci.2015.09.008 S0091-6749(15)01342-1 Short-term targeted treatment can potentially prevent fall asthma (...) exacerbations while limiting therapy exposure. We sought to compare (1) omalizumab with placebo and (2) omalizumab with an inhaled corticosteroid (ICS) boost with regard to fall exacerbation rates when initiated 4 to 6 weeks before return to school. A 3-arm, randomized, double-blind, double placebo-controlled, multicenter clinical trial was conducted among inner-city asthmatic children aged 6 to 17 years with 1 or more recent exacerbations (clincaltrials.gov #NCT01430403). Guidelines-based therapy

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

266. [Omalizumab for the management of asthma]

[Omalizumab for the management of asthma] Omalizumab para el tratamiento del asma [Omalizumab for the management of asthma] Omalizumab para el tratamiento del asma [Omalizumab for the management of asthma] Ruano Gándara R, Rey-Ares L, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, Ciapponi A, López A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been (...) made for the HTA database. Citation Ruano Gándara R, Rey-Ares L, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, Ciapponi A, López A. Omalizumab para el tratamiento del asma. [Omalizumab for the management of asthma] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No. 440. 2015 Authors' objectives To assess the available evidence on the efficacy, safety and coverage related aspects regarding omalizumab in the management

Health Technology Assessment (HTA) Database.2015

267. The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: A Review of Latest Findings

The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: A Review of Latest Findings 26337065 2016 05 11 2018 11 13 2196-5412 2 4 2015 Dec Current environmental health reports Curr Environ Health Rep The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: a Review of Latest Findings. 379-87 10.1007/s40572-015-0066-8 In recent years, the impact of environmental exposure to chemicals and their immunological effects, including the development (...) of allergy, has been a topic of great interest. Epidemiologic studies indicate that exposure to endocrine-disrupting chemicals produced in high volumes, including bisphenol A (BPA) and phthalates, is ubiquitous. The links between their exposure and the development of allergy, asthma, and immune dysfunction have been studied in vitro, in vivo, and through human cohort studies. The purpose of this review is to examine the current body of research and to highlight deficits and strengths of current findings

Current environmental health reports2015 Full Text: Link to full Text with Trip Pro

268. A randomized, controlled, crossover study in patients with mild and moderate asthma undergoing treatment with traditional Chinese acupuncture.

A randomized, controlled, crossover study in patients with mild and moderate asthma undergoing treatment with traditional Chinese acupuncture. 26598077 2015 11 24 2016 03 15 2017 02 20 1980-5322 70 10 2015 Oct Clinics (Sao Paulo, Brazil) Clinics (Sao Paulo) A randomized, controlled, crossover study in patients with mild and moderate asthma undergoing treatment with traditional Chinese acupuncture. 663-9 10.6061/clinics/2015(10)01 S1807-59322015001000663 This study sought to verify the effects (...) of acupuncture as an adjuvant treatment for the control of asthma. This was a randomized, controlled, crossover trial conducted at the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. A total of 74 patients with mild/moderate, persistent asthma were randomized into two therapeutic groups: Group A - 31 patients underwent 10 real weekly acupuncture sessions, followed by a 3-week washout period and 10 sham weekly acupuncture sessions; and Group B - 43 patients underwent 10 sham

Clinics (São Paulo, Brazil)2015 Full Text: Link to full Text with Trip Pro

269. Are antibiotics effective in acute flares of chronic asthma?

Are antibiotics effective in acute flares of chronic asthma? Are antibiotics effective in acute flares of chronic asthma? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Are antibiotics effective in acute flares of chronic asthma? View/ Open Date 2015-09 Format Metadata Abstract Are antibiotics effective in acute (...) flares of chronic asthma? Evidence-Based Answer: In patients with acute asthma flares, at least 3 weeks of macrolide therapy added to standard asthma care may be associated with improved symptom control (SOR: B, meta analysis of RCTs). There does not appear to be any benefit with amoxicillin (SOR: B, meta-analysis) or macrolide therapy for 16 weeks (SOR: B, RCTs). URI Part of Citation Evidence-based practice 18, no. 09 (2015): E3-E4 Collections hosted by hosted by

Evidence Based Practice 2015

270. Measurement of exhaled nitric oxide concentration in asthma: a systematic review and economic evaluation of NIOX MINO, NIOX VERO and NObreath

Measurement of exhaled nitric oxide concentration in asthma: a systematic review and economic evaluation of NIOX MINO, NIOX VERO and NObreath Measurement of exhaled nitric oxide concentration in asthma: a systematic review and economic evaluation of NIOX MINO, NIOX VERO and Nobreath Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from (...) the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} The study found that evidence on the measurement of the fraction of exhaled nitric oxide (FeNO) in the breath of patients with symptoms of asthma is difficult to interpret or inconclusive with regard to its role in diagnosis or management but that economic analysis indicates that FeNO monitoring could have value in diagnostic

NIHR HTA programme2015

271. Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial.

Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial. 26505596 2015 10 28 2015 11 10 2016 10 17 1538-3598 314 16 2015 Oct 27 JAMA JAMA Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial. 1720-30 10.1001/jama.2015.13277 The efficacy and safety of long-acting β-agonists (LABAs) have been questioned. Black (...) populations may be disproportionately affected by LABA risks. To compare the effectiveness and safety of tiotropium vs LABAs, when used with inhaled corticosteroids (ICS) in black adults with asthma and to determine whether allelic variation at the Arg16Gly locus of the β2-adrenergic receptor (ADRB2) geneis associated with treatment response. A multisite (n = 20), open-label, parallel-group, pragmatic randomized clinical trial conducted from March 2011 through July 2013, enrolling black adults

JAMA2015 Full Text: Link to full Text with Trip Pro

272. Diagnosis and management of asthma in preschoolers: A Canadian Thoracic Society and Canadian Paediatric Society position paper

Diagnosis and management of asthma in preschoolers: A Canadian Thoracic Society and Canadian Paediatric Society position paper Diagnosis and management of asthma in preschoolers: A Canadian Thoracic Society and Canadian Paediat | Position statements and practice points | Canadian Paediatric Society Protecting and promoting the health and well-being of children and youth CPS Member Login | Who We Are What We Do Get Involved Education/CPD Publications Careers > Share POSITION STATEMENT Diagnosis (...) and management of asthma in preschoolers: A Canadian Thoracic Society and Canadian Paediatric Society position paper Posted: Oct 5 2015 The Canadian Paediatric Society gives permission to print single copies of this document from our website. For permission to reprint or reproduce multiple copies, please see our . Principal author(s) Francine M Ducharme, Sharon D Dell, Dhenuka Radhakrishnan,Roland M Grad, Wade TA Watson, Connie L Yang, Mitchell Zelman , Can Respir J 2015;22(3): 135-143 Abstract Asthma often

Canadian Paediatric Society2015

273. Pulse oximeters to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma.

Pulse oximeters to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma. BACKGROUND: We became aware through talking with people with asthma that some are using pulse oximeters to monitor their own blood oxygen levels during an asthma attack. Pulse oximeters are marketed by some suppliers as essential equipment for the home medicine cabinet. We wanted to find out if reliable evidence is available on use of pulse oximeters to self monitor (...) asthma exacerbations at home. We decided to include only trials that used pulse oximeters as part of a personalised asthma action plan because it is important that decisions are made on the basis of symptoms as well as oxygen saturation, and that patients have a clear protocol to follow when their asthma worsens. OBJECTIVES: To determine whether pulse oximeters used as part of a personalised asthma action plan for people with asthma are safer and more effective than a personalised asthma action plan

Cochrane2015

274. Intravenous Magnesium Sulphate for Pre-Hospital Management of Refractory Asthma: Clinical Effectiveness and Guidelines

Intravenous Magnesium Sulphate for Pre-Hospital Management of Refractory Asthma: Clinical Effectiveness and Guidelines Intravenous Magnesium Sulphate for Pre-Hospital Management of Refractory Asthma: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Intravenous Magnesium Sulphate for Pre-Hospital Management of Refractory Asthma: Clinical Effectiveness and Guidelines Intravenous Magnesium Sulphate for Pre-Hospital Management of Refractory Asthma: Clinical (...) Effectiveness and Guidelines Published on: September 2, 2015 Project Number: RB0906-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of intravenous administration of magnesium sulphate for the treatment of acute and unrelieved, refractory asthma-related bronchospasm in prehospital settings? What are the evidence-based guidelines regarding the intravenous administration of magnesium sulphate for the treatment of acute

Canadian Agency for Drugs and Technologies in Health - Rapid Review2015

275. Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines

Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines Published on: August 27, 2015 (...) Project Number: RC0696-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of bronchial thermoplasty for patients with severe asthma? What is the cost-effectiveness of bronchial thermoplasty for patients with severe asthma? What are the evidence-based guidelines regarding the use of bronchial thermoplasty for patients with severe asthma? Key Message Three randomized clinical trials, two

Canadian Agency for Drugs and Technologies in Health - Rapid Review2015

276. Community Health Worker Home Visits for Medicaid-Enrolled Children With Asthma: Effects on Asthma Outcomes and Costs

Community Health Worker Home Visits for Medicaid-Enrolled Children With Asthma: Effects on Asthma Outcomes and Costs 26270287 2015 10 10 2016 01 26 2016 04 21 1541-0048 105 11 2015 Nov American journal of public health Am J Public Health Community Health Worker Home Visits for Medicaid-Enrolled Children With Asthma: Effects on Asthma Outcomes and Costs. 2366-72 10.2105/AJPH.2015.302685 We sought to estimate the return on investment of a streamlined version of an evidence-based community health (...) worker (CHW) asthma home visit program. We used a randomized parallel group trial of home visits by CHWs to Medicaid-enrolled children with uncontrolled asthma versus usual care. A total of 373 participants enrolled in the study (182 in the intervention group and 191 in the control group, of whom 154 and 179, respectively, completed the study). The intervention group had greater improvements in asthma symptom-free days (2.10 days more over 2 weeks; 95% CI = 1.17, 3.05; P < .001) and caretakers

EvidenceUpdates2015

277. Mometasone Furoate (Asmanex Twisthaler) for asthma. It is inhaled, but does not aspire...for something more

Mometasone Furoate (Asmanex Twisthaler) for asthma. It is inhaled, but does not aspire...for something more 2015. DAR No 2: Mometasone Furoate. Asmanex Twisthaler® for asthma management - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DAR No 2: Mometasone Furoate. Asmanex Twisthaler® for asthma management DAR No 2: Mometasone Furoate. Asmanex Twisthaler® for asthma management Content tools Share it It is inhaled, but does not aspire (...) ...for something more Mometasone furoate is an inhaled glucocorticoid indicated in the maintenance treatment of persistent asthma. No advantage has been shown in terms of relevant clinical outcomes with respect to other inhaled corticosteroids. The profile of adverse effects and the administration regimen of mometasone are similar to that of other inhaled corticoids. Enviar comentario You can send us a comment or suggestion and we will respond to most frequently asked questions Competing interests (complete

Drug and Therapeutics Bulletin of Navarre (Spain)2015

278. Sublingual immunotherapy for asthma.

Sublingual immunotherapy for asthma. BACKGROUND: Asthma is a common long-term respiratory disease affecting approximately 300 million people worldwide. Approximately half of people with asthma have an important allergic component to their disease, which may provide an opportunity for targeted treatment. Sublingual immunotherapy (SLIT) aims to reduce asthma symptoms by delivering increasing doses of an allergen (e.g. house dust mite, pollen extract) under the tongue to induce immune tolerance (...) . However, it is not clear whether the sublingual delivery route is safe and effective in asthma. OBJECTIVES: To assess the efficacy and safety of sublingual immunotherapy compared with placebo or standard care for adults and children with asthma. SEARCH METHODS: We identified trials from the Cochrane Airways Group Specialised Register (CAGR), ClinicalTrials.gov (www.ClinicalTrials.gov), the World Health Organization (WHO) trials portal (www.who.int/ictrp/en/) and reference lists of all primary studies

Cochrane2015

279. Bronchial thermoplasty for the treatment of severe persistent asthma

Bronchial thermoplasty for the treatment of severe persistent asthma Bronchial thermoplasty for the treatment of severe persistent asthma Bronchial thermoplasty for the treatment of severe persistent asthma Medical Services Advisory Committee Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Medical Services Advisory Committee. Bronchial thermoplasty (...) for the treatment of severe persistent asthma. Canberra: Medical Services Advisory Committee (MSAC). MSAC application 1384. 2015 Authors' objectives Bronchial thermoplasty (BT) is performed in a bronchoscopy/endoscopy suite and takes about an hour to complete each of the three required treatments. BT is usually conducted under moderate sedation. Post-procedure, patients are observed and monitored for approximately 2-4 hours. Authors' conclusions After considering the available evidence presented in relation

Health Technology Assessment (HTA) Database.2015

280. Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma.

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma. BACKGROUND: Long-acting muscarinic antagonists (LAMA), a class of drugs with proven effectiveness in chronic obstructive pulmonary disease (COPD), are being considered as an add-on option for adults with asthma whose condition is uncontrolled on inhaled corticosteroids (ICS). It is important to assess the safety and efficacy of LAMA add-on as an alternative (...) to the prolonged use of higher doses of ICS, which are known to cause undesirable side effects in some people. OBJECTIVES: To compare the effects of adding a LAMA to any dose of ICS versus increasing the dose of ICS, for uncontrolled asthma in adults. SEARCH METHODS: We searched the Cochrane Airways Group Specialised Register (CAGR) from its inception in 1995 to April 2015, imposing no restriction on language of publication. We also handsearched trial registries, reference lists of primary studies and existing

Cochrane2015