Latest & greatest articles for asthma

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Top results for asthma

181. Adult asthma care: promoting control of asthma, second edition.

Adult asthma care: promoting control of asthma, second edition. Adult asthma care: promoting control of asthma, second edition. | National Guideline Clearinghouse success fail JUN 10 2017 2018 2019 14 Apr 2018 - 12 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group (...) at . TIMESTAMPS Search Sign In Username or Email * Password * Remember Me Don't have an account? The AHRQ National Guideline Clearinghouse (NGC, guideline.gov) Web site will not be available after July 16, 2018 because federal funding through AHRQ will no longer be available to support the NGC as of that date. For additional information, read our . Guideline Summary NGC:011235 2017 May NEATS Assessment Adult asthma care: promoting control of asthma, second edition. Registered Nurses' Association of Ontario

National Guideline Clearinghouse (partial archive)2017

182. Asthma: diagnosis, monitoring and chronic asthma management.

Asthma: diagnosis, monitoring and chronic asthma management. Asthma: diagnosis, monitoring and chronic asthma management. | National Guideline Clearinghouse success fail May JUN Jul 09 2017 2018 2019 08 Jun 2018 - 09 Jun 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group (...) at . TIMESTAMPS Search Sign In Username or Email * Password * Remember Me Don't have an account? The AHRQ National Guideline Clearinghouse (NGC, guideline.gov) Web site will not be available after July 16, 2018 because federal funding through AHRQ will no longer be available to support the NGC as of that date. For additional information, read our . Guideline Summary NGC:011311 2017 Nov 29 NEATS Assessment Asthma: diagnosis, monitoring and chronic asthma management. National Guideline Centre. Asthma: diagnosis

National Guideline Clearinghouse (partial archive)2017

183. Adult Asthma Care: Promoting Control of Asthma

Adult Asthma Care: Promoting Control of Asthma Adult Asthma Care: Promoting Control of Asthma | Registered Nurses' Association of Ontario l’Association des infirmières et infirmiers autorisés de l’Ontario Speaking out for nursing. Speaking out for health. » » Adult Asthma Care: Promoting Control of Asthma Type of Guideline: Clinical Status: Published Publish Date: 2017 About this Guideline : This nursing Best Practice Guideline (BPG) is intended to replace the RNAO BPG Adult Asthma Care (...) Guidelines for Nurses: Promoting Control of Asthma (2004) and its supplement (2007). It is to be used by nurses and other members of the interprofessional health-care team to enhance the quality of their practice pertaining to the assessment and management of adult asthma, ultimately improving clinical and health outcomes through the use of evidence-based practices. This Guideline aims to assist nurses and other health-care providers help persons with asthma achieve asthma control, thereby minimizing

Registered Nurses' Association of Ontario2017

184. Randomised controlled trial: Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood

Randomised controlled trial: Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood Article Text Therapeutics

Evidence-Based Medicine (Requires free registration)2017

185. Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring.

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring. BACKGROUND: Reduced intake of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) may be a contributing factor to the increasing prevalence of wheezing disorders. We assessed the effect of supplementation with n-3 LCPUFAs in pregnant women on the risk of persistent wheeze and asthma in their offspring. METHODS: We randomly assigned 736 pregnant women at 24 weeks of gestation to receive 2.4 g of n-3 LCPUFA (fish oil (...) ) or placebo (olive oil) per day. Their children formed the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC 2010 ) cohort and were followed prospectively with extensive clinical phenotyping. Neither the investigators nor the participants were aware of group assignments during follow-up for the first 3 years of the children's lives, after which there was a 2-year follow-up period during which only the investigators were unaware of group assignments. The primary end point

NEJM2016 Full Text: Link to full Text with Trip Pro

186. Benefit of hospital pharmacy intervention on the current status of dry powder inhaler technique in patients with asthma and COPD: a study from the Central Development Region, Nepal

Benefit of hospital pharmacy intervention on the current status of dry powder inhaler technique in patients with asthma and COPD: a study from the Central Development Region, Nepal 29354546 2018 11 13 2230-5254 6 2017 Integrated pharmacy research & practice Integr Pharm Res Pract Benefit of hospital pharmacy intervention on the current status of dry powder inhaler technique in patients with asthma and COPD: a study from the Central Development Region, Nepal. 7-13 10.2147/IPRP.S119202 (...) The majority of patients with asthma and chronic obstructive pulmonary disease (COPD) have been known to perform inhaler technique inadequately. We aimed to evaluate the benefit of hospital pharmacy intervention on the current status of dry powder inhaler (Rotahaler ® ) technique in such patients and the factors associated with the correct use. A pre-post interventional study was conducted at the outpatient pharmacy in a teaching hospital of the Central Development Region, Nepal, in patients with asthma

Integrated pharmacy research & practice2016 Full Text: Link to full Text with Trip Pro

187. Patient- and parent-initiated oral steroids for asthma exacerbations.

Patient- and parent-initiated oral steroids for asthma exacerbations. BACKGROUND: Asthma is a chronic inflammatory disease of the airways affecting an estimated 334 million people worldwide. During severe exacerbations, patients may need to attend a medical centre or hospital emergency department for treatment with systemic corticosteroids, which can be administered intravenously or orally. Some people with asthma are prescribed oral corticosteroids (OCS) for self-administration (i.e. patient (...) -initiated) or to administer to their child with asthma (i.e. parent-initiated), in the event of an exacerbation. This approach to treatment is becoming increasingly common. OBJECTIVES: To evaluate the effectiveness and safety of patient- or parent-initiated oral steroids for adults and children with asthma exacerbations. SEARCH METHODS: We identified trials from Cochrane Airways' Specialised Register (CASR) and also conducted a search of the US National Institutes of Health Ongoing Trials Register

Cochrane2016

188. Fractional exhaled nitric oxygen in asthma patients

Fractional exhaled nitric oxygen in asthma patients Fractional exhaled nitric oxygen in asthma patients Fractional exhaled nitric oxygen in asthma patients Mengarelli C, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mengarelli C (...) , Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L. Fractional exhaled nitric oxygen in asthma patients. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No. 494. 2016 Authors' conclusions Evidence of low methodological quality suggests that fractional exhaled nitric oxide to monitor glucocorticoid therapy in adult asthma patients might reduce the number of exacerbations, while the evidence

Health Technology Assessment (HTA) Database.2016

189. Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study.

Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study. BACKGROUND: Low-dose inhaled corticosteroids (ICS) are highly effective for reducing asthma exacerbations and mortality. Conventionally, ICS treatment is recommended for patients with symptoms on more than 2 days per week, but this criterion has scant evidence. We aimed to assess the validity of the previous symptom-based cutoff (...) for starting ICS by establishing whether there was a differential response to budesonide versus placebo for severe asthma exacerbations, lung function, and asthma symptom control across subgroups identified by baseline asthma symptom frequency. METHODS: We did a post-hoc analysis of the 3 year inhaled Steroid Treatment As Regular Therapy (START) study, done in 32 countries, with clinic visits every 3 months. Patients (aged 4-66 years) with mild asthma diagnosed within the previous 2 years and no previous

Lancet2016

190. Breathe Easy at Home: A Qualitative Evaluation of a Pediatric Asthma Intervention

Breathe Easy at Home: A Qualitative Evaluation of a Pediatric Asthma Intervention 28462348 2018 11 13 2333-3936 3 2016 Jan-Dec Global qualitative nursing research Glob Qual Nurs Res Breathe Easy at Home: A Qualitative Evaluation of a Pediatric Asthma Intervention. 2333393616676154 10.1177/2333393616676154 The Breathe Easy at Home Program enables clinicians to refer asthmatic patients to Boston Inspectional Services Department (ISD) if they suspect housing conditions trigger symptoms (...) group highlighted successes of an unusual institutional collaboration. Interviews and focus groups identified strong and personal rapport between clinicians, inspectors, and patients as key to program retention, and that participating families required additional support throughout the process. Despite recommendations for improvement in program implementation, clinicians, inspectors, and stakeholders felt that the program overall improved both the home environment and asthma outcomes. Rosofsky Anna

Global qualitative nursing research2016 Full Text: Link to full Text with Trip Pro

191. A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of asthma (the AZALEA trial)

A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of asthma (the AZALEA trial) A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of asthma (the AZALEA trial) Journals Library An error occurred retrieving content to display, please try again (...) . >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} In adults with acute exacerbations of asthma, giving azithromycin in addition to standard care produced no statistically significant or clinically important benefit. {{author}} {{($index

NIHR HTA programme2016

192. Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil Counts

Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil Counts 27018175 2016 03 28 2017 02 03 1931-3543 150 4 2016 Oct Chest Chest Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil Counts. 799-810 S0012-3692(16)45715-6 10.1016/j.chest.2016.03.018 IL-5, a mediator of eosinophil activity, is an important potential treatment target in patients with uncontrolled asthma (...) . The efficacy of reslizumab, a humanized anti-human IL-5 monoclonal antibody, has been characterized in patients with blood eosinophils ≥ 400 cells/μL. This study further characterizes the efficacy and safety of reslizumab in patients with poorly-controlled asthma, particularly those with eosinophils < 400 cells/μL. Patients were randomly assigned to intravenous reslizumab 3.0 mg/kg or placebo once every 4 weeks for 16 weeks. The primary end point was the change in FEV1 from baseline to week 16. Secondary

EvidenceUpdates2016

193. Randomized Trial of Once-Daily Fluticasone Furoate in Children with Inadequately Controlled Asthma

Randomized Trial of Once-Daily Fluticasone Furoate in Children with Inadequately Controlled Asthma 27622699 2016 09 13 2017 05 17 2017 05 17 1097-6833 178 2016 Nov The Journal of pediatrics J. Pediatr. Randomized Trial of Once-Daily Fluticasone Furoate in Children with Inadequately Controlled Asthma. 246-253.e2 S0022-3476(16)30669-2 10.1016/j.jpeds.2016.08.010 To evaluate the dose-response, efficacy, and safety of fluticasone furoate (FF; 25 µg, 50 µg, and 100 µg), administered once daily (...) in the evening during a 12-week treatment period to children with inadequately controlled asthma. This was a Phase IIb, multicenter, stratified, randomized, double-blind, double-dummy, parallel-group, placebo- and active-controlled study in children aged 5-11 years with inadequately controlled asthma. The study comprised a 4-week run-in period, 12-week treatment period, and 1-week follow-up period. Children were randomized to receive either placebo once daily, fluticasone propionate (FP) 100 µg twice daily

EvidenceUpdates2016

194. Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels: A Randomized Phase 3 Study

Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels: A Randomized Phase 3 Study 27056586 2016 04 08 2017 02 03 1931-3543 150 4 2016 Oct Chest Chest Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels: A Randomized Phase 3 Study. 789-798 S0012-3692(16)47551-3 10.1016/j.chest.2016.03.032 This phase 3 study further characterizes the efficacy and safety of reslizumab (a humanized anti-IL-5 monoclonal antibody) in patients aged 12 to 75 (...) years with asthma inadequately controlled by at least a medium-dose inhaled corticosteroid and with a blood eosinophil count ≥ 400 cells/μL. Patients were randomized to receive reslizumab 0.3 or 3.0 mg/kg or placebo administered once every 4 weeks for 16 weeks (total four doses). The primary end point was change from baseline in pre-bronchodilator FEV1 over 16 weeks. Secondary end points included FVC, forced expiratory flow at 25% to 75% of FVC (FEF25%-75%), patient-reported control of asthma

EvidenceUpdates2016

195. British guideline on the management of asthma

British guideline on the management of asthma Evidence www.healthcareimprovementscotland.org Edinburgh Office | Gyle Square |1 South Gyle Crescent | Edinburgh | EH12 9EB Telephone 0131 623 4300 Fax 0131 623 4299 Glasgow Office | Delta House | 50 West Nile Street | Glasgow | G1 2NP Telephone 0141 225 6999 Fax 0141 248 3776 The Healthcare Environment Inspectorate, the Scottish Health Council, the Scottish Health Technologies Group, the Scottish Intercollegiate Guidelines Network (SIGN (...) ) and the Scottish Medicines Consortium are key components of our organisation. SIGN 153 • British guideline on the management of asthma A national clinical guideline September 2016 KEY TO EVIDENCE STATEMENTS AND GRADES OF RECOMMENDATIONS LEVELS OF EVIDENCE 1 ++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias 1 + Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias 1 - Meta-analyses, systematic reviews, or RCTs with a high risk of bias 2

British Thoracic Society2016

196. Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma

Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma 27726946 2016 10 11 2017 04 09 1097-6825 139 4 2017 Apr The Journal of allergy and clinical immunology J. Allergy Clin. Immunol. Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma. 1167-1175.e2 S0091-6749(16)30891-0 10.1016/j.jaci.2016.08.008 Studies show that mepolizumab can reduce the frequency of clinically significant exacerbations (...) in patients with severe eosinophilic asthma, compared with placebo. However, important events such as hospitalizations and emergency room visits are rare and difficult to characterize in single studies. We sought to compare hospitalization or hospitalization and/or emergency room visit rates in patients with severe eosinophilic asthma treated with mepolizumab or placebo in addition to standard of care for at least 24 weeks. This study was conducted and reported in accordance with the Preferred Reporting

EvidenceUpdates2016

197. Leukotriene B4 levels in sputum from asthma patients

Leukotriene B4 levels in sputum from asthma patients 28053970 2018 11 13 2312-0541 2 4 2016 Oct ERJ open research ERJ Open Res Leukotriene B4 levels in sputum from asthma patients. 00088-2015 10.1183/23120541.00088-2015 Poor asthma control is associated with increased airway neutrophils. Leukotriene B4 (LTB4) is a potent neutrophil chemoattractant. We examined the levels of LTB4 levels in the sputum of asthma patients and the relationship with disease severity. 47 asthma patients (categorised (...) according to Global Initiative for Asthma treatment stage) and 12 healthy controls provided sputum samples that were processed first with PBS to obtain supernatants and secondly with dithiothreitol (DTT) to obtain supernatants. LTB4 levels were determined by ELISA. LTB4 levels were significantly higher in step 1 (steroid naïve) and step 3 (inhaled corticosteroid (ICS) plus long acting β-agonist) patients than step 2 patients (ICS alone) (p=0.02 and p=0.01, respectively). There was very good correlation

ERJ open research2016 Full Text: Link to full Text with Trip Pro

198. British guideline on the management of asthma

British guideline on the management of asthma Evidence www.healthcareimprovementscotland.org Edinburgh Office | Gyle Square |1 South Gyle Crescent | Edinburgh | EH12 9EB Telephone 0131 623 4300 Fax 0131 623 4299 Glasgow Office | Delta House | 50 West Nile Street | Glasgow | G1 2NP Telephone 0141 225 6999 Fax 0141 248 3776 The Healthcare Environment Inspectorate, the Scottish Health Council, the Scottish Health Technologies Group, the Scottish Intercollegiate Guidelines Network (SIGN (...) ) and the Scottish Medicines Consortium are key components of our organisation. SIGN 153 • British guideline on the management of asthma A national clinical guideline September 2016 KEY TO EVIDENCE STATEMENTS AND GRADES OF RECOMMENDATIONS LEVELS OF EVIDENCE 1 ++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias 1 + Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias 1 - Meta-analyses, systematic reviews, or RCTs with a high risk of bias 2

SIGN2016

199. Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma

Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma | Clinical Correlations Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma September 21, 2016 By James Barger Peer Reviewed Asthma, an obstructive pulmonary disease characterized by bronchospasm and chronic airway inflammation, has afflicted mankind for millennia. In the 1 st century AD, the Greek physician Aretaeus of Cappadocia described an attack thus (...) : “the cheeks are ruddy, eyes protuberant, as if from strangulation…voice liquid and without resonance…they breathe standing, as if desiring to draw in all the air which they possibly can inhale, and, in their want of air they also open the mouth as if thus to enjoy the more of it…cough incessant and laborious, expectoration small, thin…and if these ” 1 At the dawn of modern medicine in the 19 th century, many physicians believed that asthma had an infectious source; others, like William Osler, believed

Clinical Correlations2016

200. Cognitive behavioural therapy (CBT) for adults and adolescents with asthma.

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma. BACKGROUND: People with asthma have a higher prevalence of anxiety and depression than the general population. This is associated with poorer asthma control, medication adherence, and health outcomes. Cognitive behavioural therapy (CBT) may be a way to improve the quality of life of people with asthma by addressing associated psychological issues, which may lead to a lower risk of exacerbations and better asthma control (...) . OBJECTIVES: To assess the efficacy of CBT for asthma compared with usual care. SEARCH METHODS: We searched the Cochrane Airways Group Specialised Register, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP). We also searched reference lists of all primary studies and review articles and contacted authors for unpublished data. The most recent searches were conducted in August 2016. SELECTION CRITERIA: We included parallel randomised controlled

Cochrane2016