Latest & greatest articles for anxiety

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on anxiety or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on anxiety and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anxiety

Anxiety is the subjectively feelings of dread over anticipated events and it is different from fear. Clinical anxiety is a group of mental disorders with generalised anxiety disorder (GAD) being the most common (approximately 22% of primary care attendances for anxiety are classed as GAD). Overall, there is a lifetime prevalence rate of 4-7%. Anxiety can be caused by a number of factors typically classified as environmental surroundings and genetic.

In the past few decades anxiety research has significantly increased. In 2000 there were approximately 430 trials looking at anxiety and by 2015 to over 1,000. This has allowed medical professionals to develop and improve accurate diagnosis and treatments in patients suffering from the condition.

Anxiety is normal in uncomfortable environments or stressful situations. However, some individuals experience intense and persistent amounts of anxiety which needs to be kept under control. Treatments include pharmaceuticals such as SSRIs, benzodiazepines, pregabalin and gabapentin. Other therapies include CBT, acceptance and commitment therapy, and motivational interviewing.

Trip has all the latest evidence relating to treatments for anxiety, this includes systematic reviews, clinical guidelines, controlled trials, evidence-based synopses, case reports and clinical Q&As.

Top results for anxiety

362. Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies

Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies 18480688 2008 05 15 2008 09 11 2012 11 15 0271-0749 28 3 2008 Jun Journal of clinical psychopharmacology J Clin Psychopharmacol Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies. 308-16 10.1097/JCP.0b013e318172b45f The objective of these studies (...) was to evaluate the efficacy and tolerability of tiagabine, a selective gamma-aminobutyric acid reuptake inhibitor, in adult patients with generalized anxiety disorder (GAD). Patients with a diagnosis of GAD were enrolled in 1 of 3 randomized, placebo-controlled, 10-week studies. In each study, tiagabine was taken twice daily in divided doses--4, 8, or 12 mg/d in a fixed-dose study and 4-16 mg/d in two flexible-dose trials. The primary efficacy measure was the change from baseline in the 14-item Hamilton

EvidenceUpdates2008

363. Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder

Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder Article Text Therapeutics Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder Statistics from Altmetric.com No Altmetric data available

Evidence-Based Mental Health2008

364. Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease

Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease Article Text Prognosis Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease Statistics from

Evidence-Based Mental Health2008

365. Effectiveness of complementary and self-help treatments for anxiety in children and adolescents

Effectiveness of complementary and self-help treatments for anxiety in children and adolescents 18341460 2008 03 17 2008 05 22 2008 03 17 0025-729X 188 6 2008 Mar 17 The Medical journal of Australia Med. J. Aust. Effectiveness of complementary and self-help treatments for anxiety in children and adolescents. 355-9 To review the evidence for the effectiveness of complementary and self-help treatments for anxiety disorders and situational anxiety in children and adolescents. Systematic literature (...) , a mineral-vitamin supplement (EMPower +) and music therapy. Findings from case-control studies, individual cohort studies or low quality randomised controlled trials indicated that several treatments may have potential to reduce anxiety, including bibliotherapy, massage, melatonin, and relaxation training. Although some complementary and self-help treatments might be useful for children and adolescents with anxiety, they need to be tested adequately through randomised controlled trials before they could

EvidenceUpdates2008

366. Social anxiety disorder.

Social anxiety disorder. Our understanding of social anxiety disorder (also known as social phobia) has moved from rudimentary awareness that it is not merely shyness to a much more sophisticated appreciation of its prevalence, its chronic and pernicious nature, and its neurobiological underpinnings. Social anxiety disorder is the most common anxiety disorder; it has an early age of onset--by age 11 years in about 50% and by age 20 years in about 80% of individuals--and it is a risk factor (...) for subsequent depressive illness and substance abuse. Functional neuroimaging studies point to increased activity in amygdala and insula in patients with social anxiety disorder, and genetic studies are increasingly focusing on this and other (eg, personality trait neuroticism) core phenotypes to identify risk loci. A range of effective cognitive behavioural and pharmacological treatments for children and adults now exists; the challenges lie in optimum integration and dissemination of these treatments

Lancet2008

367. Pattern of perceived stress and anxiety in pregnancy predicts preterm birth

Pattern of perceived stress and anxiety in pregnancy predicts preterm birth 18230013 2008 01 30 2008 04 15 2015 11 19 0278-6133 27 1 2008 Jan Health psychology : official journal of the Division of Health Psychology, American Psychological Association Health Psychol Pattern of perceived stress and anxiety in pregnancy predicts preterm birth. 43-51 10.1037/0278-6133.27.1.43 To determine whether the pattern of prenatal stress, as compared to prenatal stress assessed at a single gestational time (...) point, predicts preterm delivery (PTD). Perceived stress and anxiety were assessed in 415 pregnant women at 18-20 and 30-32 weeks' gestation. Gestational length was determined by last menstrual period and confirmed by early pregnancy ultrasound. Births were categorized as preterm (< 37 weeks) or term. At neither assessment did levels of anxiety or perceived stress predict PTD. However, patterns of anxiety and stress were associated with gestational length. Although the majority of women who

EvidenceUpdates2008

368. Pregabalin and venlafaxine improve symptoms of generalised anxiety disorder

Pregabalin and venlafaxine improve symptoms of generalised anxiety disorder Pregabalin and venlafaxine improve symptoms of generalised anxiety disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Pregabalin and venlafaxine improve symptoms of generalised anxiety disorder Article Text Therapeutics Pregabalin and venlafaxine improve symptoms of generalised anxiety disorder Statistics from Altmetric.com No Altmetric data available for this article. Request permissions If you wish to reuse any or all of this article please use the link below

Evidence-Based Mental Health2008

369. Bibliotherapy is more effective than waiting list for reducing childhood anxiety disorder, but not as effective as group cognitive behavioural therapy

Bibliotherapy is more effective than waiting list for reducing childhood anxiety disorder, but not as effective as group cognitive behavioural therapy Bibliotherapy is more effective than waiting list for reducing childhood anxiety disorder, but not as effective as group cognitive behavioural therapy | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Bibliotherapy is more effective than waiting list for reducing childhood anxiety disorder, but not as effective as group cognitive behavioural therapy Article Text Therapeutics Bibliotherapy is more

Evidence-Based Mental Health2008

370. Increased prevalence of post-traumatic stress disorder, anxiety and depression in displaced tsunami survivors from southern Thailand

Increased prevalence of post-traumatic stress disorder, anxiety and depression in displaced tsunami survivors from southern Thailand Increased prevalence of post-traumatic stress disorder, anxiety and depression in displaced tsunami survivors from southern Thailand | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Increased prevalence of post-traumatic stress disorder, anxiety and depression in displaced tsunami survivors from southern Thailand Article Text Prevalence Increased prevalence of post-traumatic stress disorder, anxiety and depression

Evidence-Based Mental Health2008

371. Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials

Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials Klassen JA, Liang Y, Tjosvold L, Klassen TP, Hartling L CRD summary This well-conducted review concluded that music therapy (...) was effective in reducing anxiety and pain in children who underwent medical and dental procedures. The results appeared promising, but as they were based on largely poor quality studies the authors' conclusions should be considered provisional. Authors' objectives To review the efficacy of music therapy in reducing pain and anxiety in children undergoing medical procedures. Searching MEDLINE, ERIC, Cochrane Central Register of Controlled Trials (CENTRAL), The Cochrane Library, Online Computer Library

DARE.2008

372. Effects of music listening on adult patients' pre-procedural state anxiety in hospital

Effects of music listening on adult patients' pre-procedural state anxiety in hospital Effects of music listening on adult patients' pre-procedural state anxiety in hospital Effects of music listening on adult patients' pre-procedural state anxiety in hospital Gillen E, Biley F, Allen D CRD summary This review assessed the effectiveness of listening to music as an intervention to reduce pre-procedural state anxiety in adult hospital patients. Overall, the authors stated that psychological (...) outcomes show reduced anxiety as a result of music listening interventions. The conclusion of this relatively robust review is reasonable, but the choice of synthesis method might have overstated the benefits. Authors' objectives This review assessed the effectiveness of listening to music to reduce pre-procedural state anxiety in hospital settings. Searching The following databases were searched from January 1985 to February 2006 using the search terms and strategies reported in the paper: CINAHL

DARE.2008

373. Cost-effectiveness of escitalopram for generalized anxiety disorder in Canada

Cost-effectiveness of escitalopram for generalized anxiety disorder in Canada Cost-effectiveness of escitalopram for generalized anxiety disorder in Canada Cost-effectiveness of escitalopram for generalized anxiety disorder in Canada Iskedjian M, Walker JH, Bereza BG, Le Melledo JM, Einarson TR Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The aim was to assess the cost-effectiveness of escitalopram compared with paroxetine for generalised anxiety disorder. The authors concluded that escitalopram was more cost-effective than paroxetine, indicating an advantage over paroxetine. Overall, the methodology was satisfactory and the results were well reported. The authors' conclusions appear to be robust and appropriate. Type

NHS Economic Evaluation Database.2008

374. Analysis of health-related quality of life and costs based on a randomised clinical trial of escitalopram for relapse prevention in patients with generalised social anxiety disorder

Analysis of health-related quality of life and costs based on a randomised clinical trial of escitalopram for relapse prevention in patients with generalised social anxiety disorder Analysis of health-related quality of life and costs based on a randomised clinical trial of escitalopram for relapse prevention in patients with generalised social anxiety disorder Analysis of health-related quality of life and costs based on a randomised clinical trial of escitalopram for relapse prevention (...) in patients with generalised social anxiety disorder Francois C, Montgomery S A, Despiegel N, Aballea S, Roiz J, Auquier P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the long-term clinical and economic impact

NHS Economic Evaluation Database.2008

376. Cognitive-behavioural therapy for health anxiety in a genitourinary medicine clinic: randomised controlled trial

Cognitive-behavioural therapy for health anxiety in a genitourinary medicine clinic: randomised controlled trial Cognitive-behavioural therapy for health anxiety in a genitourinary medicine clinic: randomised controlled trial Cognitive-behavioural therapy for health anxiety in a genitourinary medicine clinic: randomised controlled trial Seivewright H, Green J, Salkovskis P, Barrett B, Nur U, Tyrer P Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to examine the clinical and economic impact of cognitive-behavioural therapy (CBT) in patients aged 16 to 65 years, with high health anxiety, in a genitourinary medicine clinic. CBT improved the clinical outcomes, although the additional costs were not offset by savings

NHS Economic Evaluation Database.2008

377. Efficacy of cognitive-behavioral and pharmacological treatments for children with social anxiety

Efficacy of cognitive-behavioral and pharmacological treatments for children with social anxiety Efficacy of cognitive-behavioral and pharmacological treatments for children with social anxiety Efficacy of cognitive-behavioral and pharmacological treatments for children with social anxiety Segool NK, Carlson JS CRD summary This review assessed the efficacy of cognitive-behavioural therapy and selective serotonin re-uptake inhibitor drug treatments for childhood social anxiety, concluding (...) that both treatments produced significant reductions in social anxiety symptoms, general anxiousness, and impairment due to social anxiety. Given the shortcomings in the review process, small sample sizes and uncertainty over methodology, the authors' conclusions should be interpreted with caution. Authors' objectives To assess the efficacy of cognitive-behavioural therapy (CBT) and selective serotonin re-uptake inhibitor (SSRI) drug treatments for childhood social anxiety. Searching MEDLINE

DARE.2008

378. The efficacy of cognitive-behavioral interventions for reducing anxiety sensitivity: a meta-analytic review

The efficacy of cognitive-behavioral interventions for reducing anxiety sensitivity: a meta-analytic review The efficacy of cognitive-behavioral interventions for reducing anxiety sensitivity: a meta-analytic review The efficacy of cognitive-behavioral interventions for reducing anxiety sensitivity: a meta-analytic review Smits JA, Berry AC, Tart CD, Powers MB CRD summary This review concluded that cognitive-behavioural therapy was efficacious in reducing anxiety sensitivity in both treatment (...) -seeking patients and those at risk. There were a number of limitations in the review which suggest that the authors' conclusions should be treated with caution. Authors' objectives To compare the efficacy of cognitive-behavioural therapy with control conditions for the reduction of anxiety sensitivity. Searching The following databases were searched: PsycINFO, MEDLINE and Scopus from 1986 to February 2008. The search start date was the year that the Anxiety Sensitivity Index (ASI) was developed

DARE.2008

379. Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials

Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials Hofmann S G, Smits J A CRD summary The authors concluded that cognitive behavioural therapy was effective for adults with anxiety disorders (...) , but that there was room for improvement. In view of the apparently limited quality of the heterogeneous studies and generally small sample sizes the authors’ conclusions should be interpreted with caution. Authors' objectives To evaluate the efficacy of cognitive behavioural therapy (CBT) in adults with anxiety disorders. Searching MEDLINE via PubMed, PsycINFO, SCOPUS, ISI and Dissertation Abstracts International were searched from inception to March 2007. Search terms were reported. Colleagues in Germany, Japan

DARE.2008

380. Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy

Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy Coventry PA, Gellatly JL CRD summary This review concluded that there was limited evidence (...) that cognitive behavioural therapy, when used with exercise and education, could contribute to significant reductions in anxiety and depression in patients with clinically stable and severe chronic obstructive pulmonary disease. These conclusions are likely to be reliable although, as the authors stated, an adequately powered RCT is required to confirm these findings. Authors' objectives To evaluate the effectiveness of cognitive behavioural therapy in reducing mild-to-moderate anxiety and depression

DARE.2008