Latest & greatest articles for anticoagulation

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Top results for anticoagulation

441. Evaluation of excessive anticoagulation in a group model health maintenance organization

Evaluation of excessive anticoagulation in a group model health maintenance organization Evaluation of excessive anticoagulation in a group model health maintenance organization Evaluation of excessive anticoagulation in a group model health maintenance organization Lousberg T R, Witt D M, Beall D G, Carter B L, Malone D C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Using phytonadione and/or fresh frozen plasma (FFP) versus the conservative management option in the management of patients with excessive anticoagulation. The conservative management was defined as temporary discontinuation of warfarin therapy until the international normalized ratio (INR) falls to within therapeutic range. Type of intervention Secondary

NHS Economic Evaluation Database.1998

442. Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke

Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Lightowlers S, McGuire A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Anticoagulation in nonrheumatic atrial fibrillation (NRAF) in the primary prevention of ischemic stroke. Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population Patients with NRAF with no contraindication to anticoagulation. Setting Hospital

NHS Economic Evaluation Database.1998

443. Anticoagulant options in heparin-induced thrombocytopenia

Anticoagulant options in heparin-induced thrombocytopenia Anticoagulant options in heparin-induced thrombocytopenia Anticoagulant options in heparin-induced thrombocytopenia University HealthSystem Consortium Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation University HealthSystem Consortium. Anticoagulant options in heparin-induced thrombocytopenia. Oak Brook (...) , Illinois: University Healthsystem Consortium 1998: 64 Authors' objectives Provides an in-depth analysis of four alternative therapies for patients who have HIT: danaparoid sodium, lepirudin, argatroban, and ancrod. Recommendations for use also are included. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Anticoagulants; Heparin; Thrombocytopenia /drug therapy Language Published English Country of organisation United States Address for correspondence University HealthSystem

Health Technology Assessment (HTA) Database.1998

444. Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research

Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research 9457092 1998 02 19 1998 02 19 2015 06 16 0140-6736 351 9098 1998 Jan 24 Lancet (London, England) Lancet Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary (...) prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework. 233-41 We aimed to evaluate low intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease (IHD). 5499 men aged between 45 years and 69 years at high risk of IHD were recruited from 108 practices in the UK that belong to the Medical Research Council's General Practice Research Framework. Initially, warfarin

Lancet1998

445. Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation.

Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. 9820298 1998 12 04 1998 12 04 2015 06 16 0140-6736 352 9139 1998 Nov 07 Lancet (London, England) Lancet Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. 1505-9 The demand for anticoagulant treatment is increasing. We compared the benefits of computer-generated anticoagulant dosing with traditional dosing decided (...) by experienced medical staff in achieving target international normalised ratios (INRs). In five European centres we randomly assigned 285 patients in the stabilisation period and stabilised patients to the computer-generated-dose group (n=137) or traditional-dose group (n=148). Centres had a specialist interest in oral anticoagulation but no previous experience with computer-generated dosing. The computer program calculated doses and times to next visit. Our main endpoint was time spent in target INR range

Lancet1998

446. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.

A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators. 9834303 1998 12 04 1998 12 04 2013 11 21 0028-4793 339 23 1998 Dec 03 The New England journal of medicine N. Engl. J. Med. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators. 1665-71 Antithrombotic drugs are used after coronary-artery stenting to prevent (...) 20010, USA. Baim D S DS Popma J J JJ Gordon P C PC Cutlip D E DE Ho K K KK Giambartolomei A A Diver D J DJ Lasorda D M DM Williams D O DO Pocock S J SJ Kuntz R E RE eng Clinical Trial Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't United States N Engl J Med 0255562 0028-4793 0 Anticoagulants 0 Platelet Aggregation Inhibitors 5Q7ZVV76EI Warfarin OM90ZUW7M1 Ticlopidine R16CO5Y76E Aspirin AIM IM N Engl J Med. 1998 Dec 3;339(23):1702-4

NEJM1998

447. Anticoagulation in spinal surgery: a critical review of the literature

Anticoagulation in spinal surgery: a critical review of the literature Anticoagulation in spinal surgery: a critical review of the literature Anticoagulation in spinal surgery: a critical review of the literature Catre M G Authors' objectives To critically appraise the existing literature regarding thromboprophylaxis in elective spinal surgery. Searching MEDLINE was searched from 1965 to 1995 using the keywords 'anticoagulation', 'DVT' and 'spine', alone and in different combinations (...) from the findings of these studies because of the lack of good scientific evidence. Research: The author states that there is a need for a well-designed randomised, double-blind, placebo-controlled study of anticoagulation in spinal surgery. Bibliographic details Catre M G. Anticoagulation in spinal surgery: a critical review of the literature. Canadian Journal of Surgery 1997; 40(6): 413-419 Indexing Status Subject indexing assigned by NLM MeSH Adolescent; Adult; Anticoagulants /therapeutic use

DARE.1997

448. Costs and effectiveness of a nurse specialist anticoagulant service

Costs and effectiveness of a nurse specialist anticoagulant service Costs and effectiveness of a nurse specialist anticoagulant service Costs and effectiveness of a nurse specialist anticoagulant service Taylor F C, Gray A, Cohen H, Gaminara L, Ramsay M, Miller D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical (...) assessment on the reliability of the study and the conclusions drawn. Health technology A nurse specialist service in anticoagulation treatment. Type of intervention Secondary prevention. Economic study type Cost-effectiveness analysis. Study population Patients referred to anticoagulant clinics for anticoagulation treatment. Setting Institution. The economic study was performed in the UK. Dates to which data relate The authors did not clearly establish the dates to which effectiveness data referred

NHS Economic Evaluation Database.1997

449. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts. The Post Coronary Artery Bypass Graft Trial Investigators.

The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts. The Post Coronary Artery Bypass Graft Trial Investigators. 8992351 1997 01 16 1997 01 16 2016 11 24 0028-4793 336 3 1997 Jan 16 The New England journal of medicine N. Engl. J. Med. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes (...) in saphenous-vein coronary-artery bypass grafts. 153-62 Obstructive changes often occur in aortocoronary saphenous-vein bypass grafts because of atherosclerosis and thrombosis. We studied whether aggressive lowering of low-density lipoprotein (LDL) cholesterol levels or low-dose anticoagulation would delay the progression of atherosclerosis in grafts. We studied 1351 patients who had undergone bypass surgery 1 to 11 years before base line and who had an LDL cholesterol level between 130 and 175 mg per

NEJM1997

450. The duration of oral anticoagulant therapy after a second episode of venous thromboembolism. The Duration of Anticoagulation Trial Study Group.

The duration of oral anticoagulant therapy after a second episode of venous thromboembolism. The Duration of Anticoagulation Trial Study Group. 9010144 1997 02 06 1997 02 06 2013 11 21 0028-4793 336 6 1997 Feb 06 The New England journal of medicine N. Engl. J. Med. The duration of oral anticoagulant therapy after a second episode of venous thromboembolism. The Duration of Anticoagulation Trial Study Group. 393-8 A consensus has not been reached about the optimal duration of oral anticoagulant (...) therapy after a second episode of venous thromboembolism. In a multicenter trial, we compared six months of oral anticoagulant therapy with anticoagulant therapy continued indefinitely in patients who had had a second episode of venous thromboembolism. Of 227 patients enrolled, 111 were randomly assigned to six months of anticoagulation and 116 were assigned to receive anticoagulant therapy indefinitely; for both groups, the target international normalized ratio was 2.0 to 2.85. The initial episodes

NEJM1997

451. Evaluation of a decision support system for initiation and control of oral anticoagulation in a randomised trial.

Evaluation of a decision support system for initiation and control of oral anticoagulation in a randomised trial. 9154031 1997 06 09 1997 06 09 2013 11 21 0959-8138 314 7089 1997 Apr 26 BMJ (Clinical research ed.) BMJ Evaluation of a decision support system for initiation and control of oral anticoagulation in a randomised trial. 1252-6 To determine whether a computerised decision support system for initiation and control of oral anticoagulant treatment improves quality of anticoagulant control (...) after therapeutic range has been reached) and person time spent in the therapeutic range. 72 patients were randomised to the intervention group and 76 to control group. Median time to reach international normalised ratio of > or = 2 was not significantly different in the two groups (3 days). Median time to achieve a stable dose was significantly lower in intervention group than in controls (7 days v 9 days, P = 0.01) without excessive overtreatment or undertreatment with anticoagulant. Patients

BMJ1997 Full Text: Link to full Text with Trip Pro

452. Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials

Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials Collins R, MacMahon S, Flather M, Baigent C, Remvig L, Mortensen S, Appleby P, Godwin J, Yusuf S, Peto R Authors' objectives (...) To determine the effect of early anticoagulation on the mortality and other major clinical events in patients with suspected acute myocardial infarction (MI), and to assess the effect of adding heparin to aspirin. Searching A formal computer-aided literature search was undertaken. Additional materials was located by examining reference lists, and by contacting other investigators and pharmaceutical companies. Study selection Study designs of evaluations included in the review Randomised controlled trials

DARE.1996

453. Bleeding risk of combined oral anticoagulant and antiplatelet therapy in cardiovascular disease

Bleeding risk of combined oral anticoagulant and antiplatelet therapy in cardiovascular disease Bleeding risk of combined oral anticoagulant and antiplatelet therapy in cardiovascular disease Bleeding risk of combined oral anticoagulant and antiplatelet therapy in cardiovascular disease Verheugt F W Authors' objectives To assess the safety of combining oral anticoagulant and antiplatelet therapy. Searching EMBASE was searched from 1960 to 1994. [A: The search strategy was not defined. Only (...) papers written in the English language were included]. Study selection Study designs of evaluations included in the review Clinical trials, of which most were randomised, were included. Specific interventions included in the review Combinations of anticoagulants and antiplatelet therapy, compared with either intervention alone or with placebo, namely: acenocoumarin (alone and with aspirin), warfarin (alone or with placebo, aspirin or dipyridamole), aspirin (alone and with warfarin), double placebo

DARE.1996

454. Atrial fibrillation: restoration and maintenance of sinus rhythm and indications for anticoagulation therapy

Atrial fibrillation: restoration and maintenance of sinus rhythm and indications for anticoagulation therapy Atrial fibrillation: restoration and maintenance of sinus rhythm and indications for anticoagulation therapy Atrial fibrillation: restoration and maintenance of sinus rhythm and indications for anticoagulation therapy Golzari H, Cebul R D, Bahler R C Authors' objectives To review the efficacy and safety of electrical and pharmacological conversion of atrial fibrillation, strategies (...) examined in this context, along with surgical corridor and maze procedures. In addition, antithrombotic therapy is examined, and the effectiveness of warfarin, aspirin and anticoagulants is assessed. Participants included in the review Patients with atrial fibrillation. A small number of studies included patients with fibrillation after cardiac surgery. Outcomes assessed in the review The main outcome was restoration of sinus rhythm. Reduction in incidence of ischaemic stroke and emboli is also

DARE.1996

455. Cost-effectiveness of prophylactic anticoagulation prolonged after hospital discharge following general surgery

Cost-effectiveness of prophylactic anticoagulation prolonged after hospital discharge following general surgery Cost-effectiveness of prophylactic anticoagulation prolonged after hospital discharge following general surgery Cost-effectiveness of prophylactic anticoagulation prolonged after hospital discharge following general surgery Sarasin F P, Bounameaux H Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Prolonged self-administered prophylactic low-dose low-molecular-weight heparin (LMWH) during 4 weeks after hospital discharge versus anticoagulant therapy with heparin started immediately after the first clinically overt venous thromboembolism (VTE). Type of intervention Primary prevention. Economic study type Cost

NHS Economic Evaluation Database.1996

456. Antithrombotic strategy after total hip replacement: a cost-effectiveness analysis comparing prolonged oral anticoagulants with screening for deep vein thrombosis

Antithrombotic strategy after total hip replacement: a cost-effectiveness analysis comparing prolonged oral anticoagulants with screening for deep vein thrombosis Antithrombotic strategy after total hip replacement: a cost-effectiveness analysis comparing prolonged oral anticoagulants with screening for deep vein thrombosis Antithrombotic strategy after total hip replacement: a cost-effectiveness analysis comparing prolonged oral anticoagulants with screening for deep vein thrombosis Sarasin F (...) P, Bounameaux H Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Prolonged oral anticoagulant therapy was compared with screening in the prevention of deep vein thrombosis (DVT) after total hip replacement. Type of intervention

NHS Economic Evaluation Database.1996

457. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents.

A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. 8598866 1996 04 25 1996 04 25 2013 11 21 0028-4793 334 17 1996 Apr 25 The New England journal of medicine N. Engl. J. Med. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. 1084-9 The clinical benefit of coronary-artery stenting performed in conjunction with coronary angioplasty is limited by the risk of thrombotic (...) occlusion of the stent as well as hemorrhagic and vascular complications of intensive anticoagulation. We compared antiplatelet therapy with conventional anticoagulant therapy with respect to clinical outcomes 30 days after coronary-artery stenting. After successful placement of Palmaz-Schatz coronary-artery stents, 257 patients were randomly assigned to receive antiplatelet therapy (ticlopidine plus aspirin) and 260 to receive anticoagulant therapy (intravenous heparin, phenprocoumon, and aspirin). The

NEJM1996

458. A comparison of aspirin and anticoagulation following thrombolysis for myocardial infarction (the AFTER study): a multicentre unblinded randomised clinical trial.

A comparison of aspirin and anticoagulation following thrombolysis for myocardial infarction (the AFTER study): a multicentre unblinded randomised clinical trial. 8973228 1997 01 17 1997 01 17 2013 11 21 0959-8138 313 7070 1996 Dec 07 BMJ (Clinical research ed.) BMJ A comparison of aspirin and anticoagulation following thrombolysis for myocardial infarction (the AFTER study): a multicentre unblinded randomised clinical trial. 1429-31 To compare aspirin with anticoagulation with regard to risk (...) of cardiac death and reinfarction in patients who received anistreplase thrombolysis for myocardial infarction. A multicentre unblinded randomised clinical trial. 38 hospitals in six countries. 1036 patients who had been treated with anistreplase for myocardial infarction were randomly assigned to either aspirin (150 mg daily) or anticoagulation (intravenous heparin followed by warfarin or other oral anticoagulant). The trial was stopped earlier than originally intended because of the slowing rate

BMJ1996 Full Text: Link to full Text with Trip Pro

459. Costs and effects of long-term oral anticoagulant treatment after myocardial infarction.

Costs and effects of long-term oral anticoagulant treatment after myocardial infarction. 7884950 1995 04 12 1995 04 12 2016 10 17 0098-7484 273 12 1995 Mar 22-29 JAMA JAMA Costs and effects of long-term oral anticoagulant treatment after myocardial infarction. 925-8 To investigate the costs and effects of long-term oral anticoagulant treatment after myocardial infarction. Cost-effectiveness analysis, based on a randomized, double-blind, placebo-controlled trial. Sixty Dutch hospitals. A total (...) of 3404 hospital survivors of acute myocardial infarction randomized within a median period of 4 days after discharge to either oral anticoagulant treatment or placebo. The mean follow-up was 37 months. Oral anticoagulant treatment aimed at a target international normalized ratio of 2.8 to 4.8. Costs of hospital stay during readmissions, costs related to major cardiologic interventions, and costs of oral anticoagulant treatment. The costs of oral anticoagulant treatment were estimated at 394 Dutch

JAMA1995

460. Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis

Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis Cappelleri J C (...) , Fiore L D, Brophy M T, Deykin D, Lau J Authors' objectives To compare the efficacy and safety of combined oral anticoagulant and antiplatelet therapy versus oral anticoagulants alone after prosthetic heart valve replacement. Searching MEDLINE was searched from January 1966 to September 1994 using the keywords 'heart valve prosthesis', 'anticoagulants' and 'antiplatelet agents'. The reference lists of retrieved papers, review articles, and editorials were examined. Only articles published in English

DARE.1995