Latest & greatest articles for anticoagulation

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This page lists the very latest high quality evidence on anticoagulation and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for anticoagulation

421. Anticoagulants versus antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks.

Anticoagulants versus antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks. BACKGROUND: People with nonrheumatic atrial fibrillation who have had a transient ischemic attack or minor ischemic stroke are at risk of recurrent stroke. OBJECTIVES: The objective of this review was to compare the effect of anticoagulants with antiplatelet therapy, for secondary prevention, in people with nonrheumatic (...) atrial fibrillation and previous cerebral ischaemia. SEARCH STRATEGY: The reviewer searched the Cochrane Stroke Group trials register and contacted trialists. SELECTION CRITERIA: Randomised trials comparing oral anticoagulants with aspirin in patients with non-rheumatic atrial fibrillation and a previous transient ischaemic attack or minor ischaemic stroke. DATA COLLECTION AND ANALYSIS: One reviewer extracted the data. MAIN RESULTS: One trial was included, involving 455 patients. They received either

Cochrane2000

422. Anticoagulants for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks.

Anticoagulants for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks. BACKGROUND: People with nonrheumatic atrial fibrillation who have had a transient ischemic attack or a minor ischemic stroke are at risk of recurrent stroke. OBJECTIVES: The objective of this review was to assess the effect of anticoagulants for secondary prevention, after a stroke or transient ischaemic attack, in patients with nonrheumatic (...) atrial fibrillation. SEARCH STRATEGY: The reviewer searched the Cochrane Stroke Group trials register and contacted trialists. SELECTION CRITERIA: Randomised trials comparing oral anticoagulants (target International Normalised Ratio range 2.5 to 4.0) with control or placebo in people with nonrheumatic atrial fibrillation and a previous transient ischaemic attack or minor ischaemic stroke. DATA COLLECTION AND ANALYSIS: One reviewer assessed trial quality and extracted data. MAIN RESULTS: Two trials involving 485

Cochrane2000

423. Anticoagulants for preventing recurrence following ischaemic stroke or transient ischaemic attack.

Anticoagulants for preventing recurrence following ischaemic stroke or transient ischaemic attack. BACKGROUND: After a first stroke, further vascular events (especially myocardial infarction and recurrent stroke) are common and often fatal. OBJECTIVES: The objective of this review was to assess the effect of prolonged anticoagulant therapy following presumed non-embolic ischaemic stroke or transient ischaemic attack. SEARCH STRATEGY: We searched the Cochrane Stroke Group trials register. We (...) contacted companies marketing anticoagulant agents. SELECTION CRITERIA: Randomised and quasi-randomised trials comparing anticoagulant therapy, for at least one month, with control in people with previous non-embolic presumed ischaemic stroke or transient ischaemic attack. DATA COLLECTION AND ANALYSIS: Two reviewers independently selected trials for inclusion, assessed trial quality and extracted the data. MAIN RESULTS: Nine trials involving 1214 patients were included. The quality of all trials

Cochrane2000

424. Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks.

Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks. BACKGROUND: Non-valvular atrial fibrillation (AF) is associated with an increased risk of stroke. OBJECTIVES: The objective of this review was to characterize the efficacy and safety of oral anticoagulation (OAC) with vitamin K antagonists for the primary prevention of stroke in patients with chronic AF. SEARCH STRATEGY: We searched

Cochrane2000

425. Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis

Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis Anand S S, Yusuf S Authors' objectives To determine the effects of long-term oral anticoagulant (OA) therapy, stratified by intensity of anticoagulation and aspirin therapy, on outcomes in patients with CAD. Searching MEDLINE, EMBASE (...) . Specific interventions included in the review OAs for example, warfarin sodium, dicoumarol, marcoumar, phenprocoumon, acencoumarin, bishydroxycourmarin. Individual agents were not studied separately but results were stratified by intensity of anticoagulation. Participants included in the review Patients with coronary artery disease (CAD). Mean age ranged from 59.9 to 64.3 years. Outcomes assessed in the review The primary outcomes were: number of deaths, recurrent myocardial infarctions (MI), stroke

DARE.1999

426. Changes in bone density after exposure to oral anticoagulants: a meta-analysis

Changes in bone density after exposure to oral anticoagulants: a meta-analysis Changes in bone density after exposure to oral anticoagulants: a meta-analysis Changes in bone density after exposure to oral anticoagulants: a meta-analysis Caraballo P J, Gabriel S E, Castro M R, Atkinson E J, Melton L J Authors' objectives To determine the association between exposure to oral anticoagulants and changes in bone density. Searching MEDLINE and EMBASE were searched until April 1998 using the following (...) keywords: 'bone', 'bone density', 'densitometry' and 'osteoporosis' combined with 'vitamin K' , 'anticoagulants' plus 'oral administration', 'coumarins', '4-hydroxycoumarins' and specific names of oral anticoagulants. Reference lists of pertinent publications were handsearched. Experts on the topic were also consulted. No language restrictions were applied. Study selection Study designs of evaluations included in the review Publications reporting original data on the effect of oral anticoagulants

DARE.1999

427. Systematic review of randomized controlled trials of aspirin and oral anticoagulants in the prevention of graft occlusion and ischemic events after infrainguinal bypass surgery

Systematic review of randomized controlled trials of aspirin and oral anticoagulants in the prevention of graft occlusion and ischemic events after infrainguinal bypass surgery Systematic review of randomized controlled trials of aspirin and oral anticoagulants in the prevention of graft occlusion and ischemic events after infrainguinal bypass surgery Systematic review of randomized controlled trials of aspirin and oral anticoagulants in the prevention of graft occlusion and ischemic events (...) after infrainguinal bypass surgery Tangelder M J, Lawson J A, Algra A, Eikelboom B C Authors' objectives To determine the efficacy of antiplatelet therapy and oral anticoagulants in maintaining graft patency and preventing ischemic complications in patients after infrainguinal bypass surgery. Searching MEDLINE was searched from 1966 onwards using the keywords 'aspirin', 'acetylsalicylic acid', 'antiplatelet', '(oral) anticoagulants', 'anticoagulation', 'phenprocoumon', 'warfarin', 'peripheral

DARE.1999

428. Clinical and economic effectiveness of an inpatient anticoagulation service

Clinical and economic effectiveness of an inpatient anticoagulation service Clinical and economic effectiveness of an inpatient anticoagulation service Clinical and economic effectiveness of an inpatient anticoagulation service Mamdani M M, Racine E, McCreadie S, Zimmerman C, O'Sullivan T L, Jensen G, Ragatzki P, Stevenson J G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Implementing a pharmacist-managed anticoagulation service for inpatient treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE). A 24-hour, 7-day/week pharmacist-managed anticoagulation service was established to provide dosing and monitoring of unfractionated heparin (UFH) and warfarin therapies at the request of a physician

NHS Economic Evaluation Database.1999

429. A structured teaching and self-management program for patients receiving oral anticoagulation: a randomized controlled trial. Working Group for the Study of Patient Self-Management of Oral Anticoagulation.

A structured teaching and self-management program for patients receiving oral anticoagulation: a randomized controlled trial. Working Group for the Study of Patient Self-Management of Oral Anticoagulation. 9917117 1999 01 27 1999 01 27 2016 10 17 0098-7484 281 2 1999 Jan 13 JAMA JAMA A structured teaching and self-management program for patients receiving oral anticoagulation: a randomized controlled trial. Working Group for the Study of Patient Self-Management of Oral Anticoagulation. 145-50 (...) Control of oral anticoagulation therapy has been reported to often be inadequate. Previous retrospective investigations suggest that patients' self-adjustment of oral anticoagulants may lead to improved control. To investigate the effects of patients' self-management of oral anticoagulation therapy on accuracy of control and measures of treatment-related quality of life. Randomized, single-blind, multicenter trial. A total of 179 patients receiving long-term oral anticoagulation treatment were

JAMA1999

430. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism.

A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. 10089183 1999 03 25 1999 03 25 2014 11 20 0028-4793 340 12 1999 Mar 25 The New England journal of medicine N. Engl. J. Med. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. 901-7 Patients who have a first episode of venous thromboembolism in the absence of known risk factors (...) for thrombosis (idiopathic thrombosis) are often treated with anticoagulant therapy for three months. Such patients may benefit from longer treatment, however, because they appear to have an increased risk of recurrence after anticoagulant therapy is stopped. In this double-blind study, we randomly assigned patients who had completed 3 months of anticoagulant therapy for a first episode of idiopathic venous thromboembolism to continue receiving warfarin, with the dose adjusted to achieve

NEJM1999

431. An overview of the effect of computer-assisted management of anticoagulant therapy on the quality of anticoagulation

An overview of the effect of computer-assisted management of anticoagulant therapy on the quality of anticoagulation An overview of the effect of computer-assisted management of anticoagulant therapy on the quality of anticoagulation An overview of the effect of computer-assisted management of anticoagulant therapy on the quality of anticoagulation Chatellier G, Colombet I, Degoulet P Authors' objectives To assess the effectiveness of computer-assisted prescription systems on the quality (...) of anticoagulation. Searching The authors searched MEDLINE from 1966 onwards using MeSH keywords: 'computer systems', 'decision- making', computer-assisted'; 'drug therapy', 'computer-assisted'; 'evaluation studies'; and 'randomized controlled trials'. Keywords were searched in the title, the summary, and the subject headings of MEDLINE. The references of selected full papers were searched for additional relevant trials. Study selection Study designs of evaluations included in the review Randomised controlled

DARE.1998

432. A cost-effectiveness analysis of aspirin versus oral anticoagulants after acute myocardial infarction in Italy: equivalence of costs as a possible case for oral anticoagulants

A cost-effectiveness analysis of aspirin versus oral anticoagulants after acute myocardial infarction in Italy: equivalence of costs as a possible case for oral anticoagulants A cost-effectiveness analysis of aspirin versus oral anticoagulants after acute myocardial infarction in Italy: equivalence of costs as a possible case for oral anticoagulants A cost-effectiveness analysis of aspirin versus oral anticoagulants after acute myocardial infarction in Italy: equivalence of costs as a possible (...) case for oral anticoagulants Gianetti J, Gensini G, De Caterina R Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Aspirin (antiplatelet) and warfarin (anticoagulant) for the prevention of coronary artery disease after acute

NHS Economic Evaluation Database.1998

433. Primary care anticoagulant clinic management using computerized decision support and near patient international normalized ratio (INR) testing: routine data from a practice nurse-led clinic

Primary care anticoagulant clinic management using computerized decision support and near patient international normalized ratio (INR) testing: routine data from a practice nurse-led clinic Primary care anticoagulant clinic management using computerized decision support and near patient international normalized ratio (INR) testing: routine data from a practice nurse-led clinic Primary care anticoagulant clinic management using computerized decision support and near patient (...) international normalized ratio (INR) testing: routine data from a practice nurse-led clinic Fitzmaurice D A, Hobbs F D, Murray E T Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Primary care anticoagulant clinic management. Type of intervention

NHS Economic Evaluation Database.1998

434. Evaluation of excessive anticoagulation in a group model health maintenance organization

Evaluation of excessive anticoagulation in a group model health maintenance organization Evaluation of excessive anticoagulation in a group model health maintenance organization Evaluation of excessive anticoagulation in a group model health maintenance organization Lousberg T R, Witt D M, Beall D G, Carter B L, Malone D C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Using phytonadione and/or fresh frozen plasma (FFP) versus the conservative management option in the management of patients with excessive anticoagulation. The conservative management was defined as temporary discontinuation of warfarin therapy until the international normalized ratio (INR) falls to within therapeutic range. Type of intervention Secondary

NHS Economic Evaluation Database.1998

435. Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke

Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Cost-effectiveness of anticoagulation in nonrheumatic atrial fibrillation in the primary prevention of ischemic stroke Lightowlers S, McGuire A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Anticoagulation in nonrheumatic atrial fibrillation (NRAF) in the primary prevention of ischemic stroke. Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population Patients with NRAF with no contraindication to anticoagulation. Setting Hospital

NHS Economic Evaluation Database.1998

436. Anticoagulant options in heparin-induced thrombocytopenia

Anticoagulant options in heparin-induced thrombocytopenia Anticoagulant options in heparin-induced thrombocytopenia Anticoagulant options in heparin-induced thrombocytopenia University HealthSystem Consortium Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation University HealthSystem Consortium. Anticoagulant options in heparin-induced thrombocytopenia. Oak Brook (...) , Illinois: University Healthsystem Consortium 1998: 64 Authors' objectives Provides an in-depth analysis of four alternative therapies for patients who have HIT: danaparoid sodium, lepirudin, argatroban, and ancrod. Recommendations for use also are included. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Anticoagulants; Heparin; Thrombocytopenia /drug therapy Language Published English Country of organisation United States Address for correspondence University HealthSystem

Health Technology Assessment (HTA) Database.1998

437. Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research

Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research 9457092 1998 02 19 1998 02 19 2015 06 16 0140-6736 351 9098 1998 Jan 24 Lancet (London, England) Lancet Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary (...) prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework. 233-41 We aimed to evaluate low intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease (IHD). 5499 men aged between 45 years and 69 years at high risk of IHD were recruited from 108 practices in the UK that belong to the Medical Research Council's General Practice Research Framework. Initially, warfarin

Lancet1998

438. Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation.

Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. 9820298 1998 12 04 1998 12 04 2015 06 16 0140-6736 352 9139 1998 Nov 07 Lancet (London, England) Lancet Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. 1505-9 The demand for anticoagulant treatment is increasing. We compared the benefits of computer-generated anticoagulant dosing with traditional dosing decided (...) by experienced medical staff in achieving target international normalised ratios (INRs). In five European centres we randomly assigned 285 patients in the stabilisation period and stabilised patients to the computer-generated-dose group (n=137) or traditional-dose group (n=148). Centres had a specialist interest in oral anticoagulation but no previous experience with computer-generated dosing. The computer program calculated doses and times to next visit. Our main endpoint was time spent in target INR range

Lancet1998

439. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.

A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators. 9834303 1998 12 04 1998 12 04 2013 11 21 0028-4793 339 23 1998 Dec 03 The New England journal of medicine N. Engl. J. Med. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators. 1665-71 Antithrombotic drugs are used after coronary-artery stenting to prevent (...) 20010, USA. Baim D S DS Popma J J JJ Gordon P C PC Cutlip D E DE Ho K K KK Giambartolomei A A Diver D J DJ Lasorda D M DM Williams D O DO Pocock S J SJ Kuntz R E RE eng Clinical Trial Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't United States N Engl J Med 0255562 0028-4793 0 Anticoagulants 0 Platelet Aggregation Inhibitors 5Q7ZVV76EI Warfarin OM90ZUW7M1 Ticlopidine R16CO5Y76E Aspirin AIM IM N Engl J Med. 1998 Dec 3;339(23):1702-4

NEJM1998

440. Anticoagulation in spinal surgery: a critical review of the literature

Anticoagulation in spinal surgery: a critical review of the literature Anticoagulation in spinal surgery: a critical review of the literature Anticoagulation in spinal surgery: a critical review of the literature Catre M G Authors' objectives To critically appraise the existing literature regarding thromboprophylaxis in elective spinal surgery. Searching MEDLINE was searched from 1965 to 1995 using the keywords 'anticoagulation', 'DVT' and 'spine', alone and in different combinations (...) from the findings of these studies because of the lack of good scientific evidence. Research: The author states that there is a need for a well-designed randomised, double-blind, placebo-controlled study of anticoagulation in spinal surgery. Bibliographic details Catre M G. Anticoagulation in spinal surgery: a critical review of the literature. Canadian Journal of Surgery 1997; 40(6): 413-419 Indexing Status Subject indexing assigned by NLM MeSH Adolescent; Adult; Anticoagulants /therapeutic use

DARE.1997