Latest & greatest articles for anesthesia

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This page lists the very latest high quality evidence on anesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anesthesia

Clinical anesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of anesthesia:

  • Local and Regional
  • General
  • Sedation

Anesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of anesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of anesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of anesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in anesthesia and the advancements in anesthesia practise by searching Trip.

Top results for anesthesia

101. Articaine is superior to lidocaine in providing pulpal anesthesia

Articaine is superior to lidocaine in providing pulpal anesthesia Articaine is superior to lidocaine in providing pulpal anesthesia ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Take advantage of endorsed, discounted business products Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Make a difference with dentistry's premier charitable organization Purchase ADA products (...) is superior to lidocaine in providing pulpal anesthesia L. Virginia Powell DMD, GPR . Overview Systematic Review Conclusion Articaine provides a higher rate of anesthetic success in anesthetizing pulpal tissues than does lidocaine, although the method of administration used and the patient’s pulpal status may diminish this effect. Critical Summary Assessment Data from a randomized clinical provided evidence of the superior anesthetic qualities of 4 percent articaine compared with those of 2 percent

ADA Center for Evidence-Based Dentistry2012

102. The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia

The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia UTCAT2287, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia Clinical Question In the anesthetized patient, does the combination of ketamine (Ketalar) with midazolam (Versed) reduce the adverse effects (hallucinations) produced (...) (including the those of the oral surgeon or pediatric dentist) with special anesthetic needs. Knowledge of the adverse effects of ketamine as an anesthetic, as compared to its effects when combined with midazolam would be beneficial when considering anesthetic agents for patients during dental treatment. Specialty/Discipline (General Dentistry) (Oral Surgery) (Pediatric Dentistry) Keywords Ketamine, Midazolam, Ketalar, Versed, adverse effects ID# 2287 Date of submission: 04/19/2012 E-mail Shariff

UTHSCSA Dental School CAT Library2012

103. Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion.

Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion. UTCAT2186, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion Clinical Question In an otherwise healthy patient undergoing a Le Fort Osteotomy, will hypotensive anesthesia compared to normotensive anesthesia decrease (...) the need for a blood transfusion? Clinical Bottom Line Hypotensive anesthesia is superior to normotensive anesthesia in reducing blood loss during a Le Fort Osteotomy, thus decreasing the need for a blood transfusion. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Choi/2008 Studies of patients with intentional hypotension during orthognathic surgery Systematic Review Key results 48 articles, with 22

UTHSCSA Dental School CAT Library2012

104. Periarticular Local Anesthesia does not Improve Pain or Mobility after THA

Periarticular Local Anesthesia does not Improve Pain or Mobility after THA 22270468 2012 06 07 2012 08 17 2015 01 28 1528-1132 470 7 2012 Jul Clinical orthopaedics and related research Clin. Orthop. Relat. Res. Periarticular local anesthesia does not improve pain or mobility after THA. 1958-65 10.1007/s11999-012-2241-7 Periarticular infiltration of local anesthetic, NSAIDs, and adrenaline have been reported to reduce postoperative pain, improve mobility, and reduce hospital stay for patients (...) having THAs, but available studies have not determined whether local anesthetic infiltration alone achieves similar improvements. We therefore asked whether periarticular injection of a local anesthetic during THA reduced postoperative pain and opioid requirements and improved postoperative mobility. We randomized 96 patients to either treatment (n = 50) or control groups (n = 46). Before wound closure, the treatment group received local infiltration of 160 mL of levobupivacaine with adrenaline

EvidenceUpdates2012 Full Text: Link to full Text with Trip Pro

105. Utilization of anesthesia services during outpatient endoscopies and colonoscopies and associated spending in 2003-2009.

Utilization of anesthesia services during outpatient endoscopies and colonoscopies and associated spending in 2003-2009. CONTEXT: The frequency with which anesthesiologists or nurse anesthetists provide sedation for gastrointestinal endoscopies, especially for low-risk patients, is poorly understood and controversial. OBJECTIVE: To quantify temporal comparisons and regional variation in the use of and payment for gastroenterology anesthesia services. DESIGN, SETTING, AND PATIENTS (...) : A retrospective analysis of claims data for a 5% representative sample of Medicare fee-for-service patients (1.1 million adults) and a sample of 5.5 million commercially insured patients between 2003 and 2009. MAIN OUTCOME MEASURES: Total number of upper gastrointestinal endoscopies and colonoscopies, proportion of gastroenterology procedures with associated anesthesia claims, payments for gastroenterology anesthesia services, and proportion of services and spending for gastroenterology anesthesia delivered

JAMA2012

106. Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial

Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial 21971743 2011 11 18 2012 06 12 2013 11 21 1496-8975 58 12 2011 Dec Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial. 1083-9 (...) 10.1007/s12630-011-9593-4 Patient position after spinal anesthesia has had variable effects on blood pressure and ephedrine requirements. The aim of this study was to determine the effects that sitting the patient up for five minutes after spinal anesthesia would have on intraoperative fluid and ephedrine requirements. The study included 120 women at term gestation who were scheduled for Cesarean delivery under spinal anesthesia. After anesthetic administration, the women were randomized either to sit

EvidenceUpdates2012

107. Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45

Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45 21596878 2011 09 28 2012 07 16 2014 11 20 1526-7598 113 4 2011 Oct Anesthesia and analgesia Anesth. Analg. Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45. 778-83 10.1213/ANE.0b013e31821f950e Surgery, general anesthesia, and related events have been implicated to promote (...) cancer proliferation. We investigated the incidence of cancer within 5 years after surgery in relation to duration of anesthesia (T(ANESTH)) and also by time with bispectral index (BIS) under 45 (T(BIS<45)) serving as a proxy for more profound anesthesia exposure. New malignant diagnoses after surgery under sevoflurane anesthesia were obtained in a prospective cohort of 2972 BIS-monitored patients without any clinically diagnosed malignant disease at the time of index surgery. The risk of cancer

EvidenceUpdates2012

108. Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery

Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery Svircevic V, van Dijk D, Nierich AP, Passier MP, Kalkman CJ, van der Heijden GJ, Bax L CRD summary The review found that thoracic epidural analgesia with general anaesthesia in patients who underwent cardiac surgery reduced (...) supraventricular arrhythmia and respiratory complications. The effects on mortality, myocardial infarction and stroke were uncertain. These conclusions appear reliable in most respects but the findings about supraventricular arrhythmia should be interpreted with caution due to heterogeneity between the studies and possible bias. Authors' objectives To compare the benefits and harms of general anaesthesia with thoracic epidural anaesthesia versus general anaesthesia alone in cardiac surgery. Searching PubMed

DARE.2011

109. Dreaming in sedation during spinal anesthesia: a comparison of propofol and midazolam infusion.

Dreaming in sedation during spinal anesthesia: a comparison of propofol and midazolam infusion. 21127282 2011 04 25 2012 07 13 2015 11 19 1526-7598 112 5 2011 May Anesthesia and analgesia Anesth. Analg. Dreaming in sedation during spinal anesthesia: a comparison of propofol and midazolam infusion. 1076-81 10.1213/ANE.0b013e3182042f93 Although sedation is often performed during spinal anesthesia, the details of intraoperative dreaming have not been reported. We designed this prospective study (...) to compare 2 different IV sedation protocols (propofol and midazolam infusion) with respect to dreaming during sedation. Two hundred twenty adult patients were randomly assigned to 2 groups and received IV infusion of propofol or midazolam for deep sedation during spinal anesthesia. Patients were interviewed on emergence and 30 minutes later to determine the incidence, content, and nature of their dreams. Postoperatively, patient satisfaction with the sedation was also evaluated. Two hundred fifteen

EvidenceUpdates2011

110. Comparison of bupivacaine and 2-chloroprocaine for spinal anesthesia for outpatient surgery: a double-blind randomized trial

Comparison of bupivacaine and 2-chloroprocaine for spinal anesthesia for outpatient surgery: a double-blind randomized trial 21203878 2011 03 22 2011 08 01 2013 11 21 1496-8975 58 4 2011 Apr Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Comparison of bupivacaine and 2-chloroprocaine for spinal anesthesia for outpatient surgery: a double-blind randomized trial. 384-91 10.1007/s12630-010-9450-x We have always been searching for the ideal local anesthetic (...) for outpatient spinal anesthesia. Lidocaine has been associated with a high incidence of transient neurological symptoms, and bupivacaine produces sensory and motor blocks of long duration. Preservative-free 2-chloroprocaine (2-CP) seems to be a promising alternative, being a short-acting agent of increasing popularity in recent years. This study was designed to compare 2-CP with bupivacaine for spinal anesthesia in an elective ambulatory setting. A total of 106 patients were enrolled in this randomized

EvidenceUpdates2011

111. A Double-Blind, Randomized, Multicenter Study of MP4OX for Treatment of Perioperative Hypotension in Patients Undergoing Primary Hip Arthroplasty Under Spinal Anesthesia

A Double-Blind, Randomized, Multicenter Study of MP4OX for Treatment of Perioperative Hypotension in Patients Undergoing Primary Hip Arthroplasty Under Spinal Anesthesia 21317165 2011 03 24 2011 05 16 2015 11 19 1526-7598 112 4 2011 Apr Anesthesia and analgesia Anesth. Analg. A double-blind, randomized, multicenter study of MP4OX for treatment of perioperative hypotension in patients undergoing primary hip arthroplasty under spinal anesthesia. 759-73 10.1213/ANE.0b013e31820c7b5f MP4OX (...) (oxygenated polyethylene glycol-modified hemoglobin) is a novel oxygen therapeutic agent specifically developed to perfuse and oxygenate tissue at risk for ischemia and hypoxia. In this study, we investigated the ability of MP4OX to treat hypotensive episodes. In addition, the tolerability profile of MP4OX in a large surgical population was established. Patients from 21 study sites in 5 countries, scheduled to undergo primary hip arthroplasty under spinal anesthesia, were randomized in a double-blind

EvidenceUpdates2011

112. Thoracic epidural anesthesia improves early outcomes in patients undergoing off-pump coronary artery bypass surgery: a prospective, randomized, controlled trial

Thoracic epidural anesthesia improves early outcomes in patients undergoing off-pump coronary artery bypass surgery: a prospective, randomized, controlled trial 21245735 2011 01 26 2011 03 03 2016 11 25 1528-1175 114 2 2011 Feb Anesthesiology Anesthesiology Thoracic epidural anesthesia improves early outcomes in patients undergoing off-pump coronary artery bypass surgery: a prospective, randomized, controlled trial. 380-90 10.1097/ALN.0b013e318201f571 The aim of this two-center, open (...) , randomized, controlled trial was to evaluate the impact of thoracic epidural anesthesia on early clinical outcomes in patients undergoing off-pump coronary artery bypass surgery. Two hundred and twenty-six patients were randomized to either general anesthesia plus epidural (GAE) (n = 109) or general anesthesia only (GA) (n = 117). The primary outcome was length of postoperative hospital stay. Secondary outcomes were: arrhythmia, inotropic support, intubation time, perioperative myocardial infarction

EvidenceUpdates2011

113. Low-dose, low-concentration levobupivacaine plus fentanyl selective spinal anesthesia for knee arthroscopy: a dose finding study

Low-dose, low-concentration levobupivacaine plus fentanyl selective spinal anesthesia for knee arthroscopy: a dose finding study 21127284 2011 01 24 2011 02 28 2013 11 21 1526-7598 112 2 2011 Feb Anesthesia and analgesia Anesth. Analg. Low-dose, low-concentration levobupivacaine plus fentanyl selective spinal anesthesia for knee arthroscopy: a dose finding study. 477-80 10.1213/ANE.0b013e318202cd03 Selective sensory spinal anesthesia preserves lower limb motor function and thus facilitates (...) , respectively, bypassed the PACU (P = 0001). Ambulation took place after 70 minutes (30-130 minutes) (median [range]) in group 5 mg and 45 minutes (23-120 minutes) in group 4 mg (P = 0006). Four milligrams levobupivacaine plus 10 μg fentanyl produced adequate surgical anesthesia with the shortest time to ambulation and the highest PACU bypass rate. De Santiago Jesus J Department of Anesthesiology, Hospital USP La Colina, SC de Tenerife, 38006 Tenerife, Spain. jdesantiagom@gmail.com Santos-Yglesias Javier J

EvidenceUpdates2011

114. Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar

Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Make a difference with dentistry's premier charitable organization Take advantage (...) Evidence Education About * Associated Topics Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Arthur Jeske DMD, PhD; James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion Articaine 4%, when compared to Lidocaine 2%, provides more effective local anesthesia in the first molar region for routine dental procedures while demonstrating a similar short-term adverse effect profile. Critical Summary Assessment An appropriately designed and which

ADA Center for Evidence-Based Dentistry2011

115. Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar

Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Take advantage of endorsed, discounted business products Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Make a difference (...) Evidence Education About * Associated Topics Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Arthur Jeske DMD, PhD; James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion Articaine 4%, when compared to Lidocaine 2%, provides more effective local anesthesia in the first molar region for routine dental procedures while demonstrating a similar short-term adverse effect profile. Critical Summary Assessment An appropriately designed and which

ADA Center for Evidence-Based Dentistry2011

116. Thoracic epidural anesthesia for cardiac surgery: a randomized trial

Thoracic epidural anesthesia for cardiac surgery: a randomized trial 21239976 2011 01 26 2011 03 03 2014 11 20 1528-1175 114 2 2011 Feb Anesthesiology Anesthesiology Thoracic epidural anesthesia for cardiac surgery: a randomized trial. 262-70 10.1097/ALN.0b013e318201d2de The addition of thoracic epidural anesthesia (TEA) to general anesthesia (GA) during cardiac surgery may have a beneficial effect on clinical outcomes. TEA in cardiac surgery, however, is controversial because the insertion (...) on the frequency of major complications after elective cardiac surgery, compared with fast-track cardiac anesthesia without epidural anesthesia. Given the potentially devastating complications of an epidural hematoma after insertion of an epidural catheter, it is questionable whether this procedure should be applied routinely in cardiac surgical patients who require full heparinization. Svircevic Vesna V Anesthesiology Resident, Department of Anesthesiology, University Medical Centre Utrecht, Utrecht

EvidenceUpdates2011

118. The dose-dependent effects of phenylephrine for elective cesarean delivery under spinal anesthesia

The dose-dependent effects of phenylephrine for elective cesarean delivery under spinal anesthesia 20841418 2010 10 25 2010 11 16 2016 11 25 1526-7598 111 5 2010 Nov Anesthesia and analgesia Anesth. Analg. The dose-dependent effects of phenylephrine for elective cesarean delivery under spinal anesthesia. 1230-7 10.1213/ANE.0b013e3181f2eae1 Hypotension is the most common serious side effect of spinal anesthesia for cesarean delivery. There has been a move recently toward the use of phenylephrine (...) impact on fetal outcome. In this randomized, double-blind study, 75 women scheduled for elective cesarean delivery were allocated to receive a phenylephrine infusion at 25 μg/min, 50 μg/min, or 100 μg/min. This infusion was titrated to maintain maternal baseline systolic blood pressure (SBP), from induction of spinal anesthesia until delivery. The maternal cardiovascular variables recorded included heart rate (HR) and SBP. A suprasternal Doppler monitor measured CO and stroke volume, as well

EvidenceUpdates2011

119. Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials

Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials Schnabel A, Poepping DM, Pogatzki-Zahn EM, Zahn PK CRD summary The review (...) concluded that, compared to caudal local anaesthetics alone, caudally administered clonidine in addition to local anaesthetics provided extended duration of analgesia with a decreased incidence for analgesic rescue requirement and few adverse events. The review was generally well conducted but, due to substantial heterogeneity and potential publication bias, the authors' conclusions should be considered tentative. Authors' objectives To assess the efficacy and safety of caudal clonidine in addition

DARE.2011

120. Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts

Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Flamer D, Peng PW CRD summary This review found that ropivacaine was effective for intravenous (...) regional anaesthesia and the addition of muscle relaxants and fentanyl could reduce the local anaesthetic requirements. Insufficient information on the size of the effects, means that the reliability of the authors' conclusions is unclear. Authors' objectives To provide an updated review of drugs for intravenous regional local anaesthesia and to evaluate the efficacy of opioids and muscle relaxants as additional treatments. Searching MEDLINE and EMBASE were searched for relevant studies, published

DARE.2011