Latest & greatest articles for anesthesia

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This page lists the very latest high quality evidence on anesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anesthesia

Clinical anesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of anesthesia:

  • Local and Regional
  • General
  • Sedation

Anesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of anesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of anesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of anesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in anesthesia and the advancements in anesthesia practise by searching Trip.

Top results for anesthesia

81. Cost analysis and safety comparison of cisatracurium and atracurium in patients undergoing general anesthesia

Cost analysis and safety comparison of cisatracurium and atracurium in patients undergoing general anesthesia Cost analysis and safety comparison of cisatracurium and atracurium in patients undergoing general anesthesia Cost analysis and safety comparison of cisatracurium and atracurium in patients undergoing general anesthesia Movafegh A, Amini S, Sharifnia H, Torkamandi H, Hayatshahi A, Javadi M Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The aim was to evaluate the cost and adverse events of two neuromuscular blockers, atracurium and cisatracurium, for patients having surgery under anaesthesia. The authors concluded that the two drugs appeared to have similar safety profiles, but atracurium was cheaper. The study

NHS Economic Evaluation Database.2013

82. 4% Articaine (1:100,000 epi) Is More Effective At Pulpal Anesthesia Than 2% Lidocaine (1:100,000 epi) In Local Infiltration Anesthesia

4% Articaine (1:100,000 epi) Is More Effective At Pulpal Anesthesia Than 2% Lidocaine (1:100,000 epi) In Local Infiltration Anesthesia UTCAT2416, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title 4% Articaine (1:100,000 epi) Is More Effective At Pulpal Anesthesia Than 2% Lidocaine (1:100,000 epi) In Local Infiltration Anesthesia Clinical Question For local infiltration anesthesia, would 4% articaine (1:100,000 epi (...) ) be more effective in pulpal anesthesia than 2% lidocaine (1:100,000 epi) in dental treatments? Clinical Bottom Line In the meta-analysis of 13 different studies, articaine was found to have more efficacy than lidocaine at pulpal anesthesia. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Brandt/2011 From the pulpal anesthesia comparison only, there were 466 experimental (lidocaine) and 467 control

UTHSCSA Dental School CAT Library2013

83. Ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean section: an updated meta-analysis

Ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean section: an updated meta-analysis Ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean section: an updated meta-analysis Ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean section: an updated meta-analysis Lin FQ, Qiu MT, Ding XX, Fu SK, Li Q CRD summary This review concluded that use (...) of ephedrine and phenylephrine were equally effective for preventing maternal hypotension during caesarean section under spinal anaesthesia. Phenylephrine was superior to ephedrine for treating hypotension in women giving birth, shown by higher umbilical blood pH values. Given the limited number of included women and trials for most outcomes, these conclusions should be treated with caution. Authors' objectives To compare the efficacy of ephedrine and phenylephrine for the management of spinal anaesthesia

DARE.2013

87. Phenylephrine infusion versus bolus regimens during cesarean delivery under spinal anesthesia: a double-blind randomized clinical trial to assess hemodynamic changes

Phenylephrine infusion versus bolus regimens during cesarean delivery under spinal anesthesia: a double-blind randomized clinical trial to assess hemodynamic changes 23011562 2012 11 23 2013 01 29 2013 11 21 1526-7598 115 6 2012 Dec Anesthesia and analgesia Anesth. Analg. Phenylephrine infusion versus bolus regimens during cesarean delivery under spinal anesthesia: a double-blind randomized clinical trial to assess hemodynamic changes. 1343-50 10.1213/ANE.0b013e31826ac3db Phenylephrine is used (...) to prevent and treat hypotension during spinal anesthesia for cesarean delivery. The optimal administration regimen is undetermined. We used a Non-invasive cardiac output monitor to test the hypothesis that a fixed-rate phenylephrine infusion regimen would cause a smaller reduction in maternal cardiac output, and result in less maternal hypotension, as compared to a phenylephrine bolus regimen. This was a double-blind, randomized clinical trial of women undergoing elective cesarean delivery under spinal

EvidenceUpdates2012

88. Combination of low-dose bupivacaine and opioids provides satisfactory analgesia with less intraoperative hypotension for spinal anesthesia in cesarean section

Combination of low-dose bupivacaine and opioids provides satisfactory analgesia with less intraoperative hypotension for spinal anesthesia in cesarean section Combination of low-dose bupivacaine and opioids provides satisfactory analgesia with less intraoperative hypotension for spinal anesthesia in cesarean section Combination of low-dose bupivacaine and opioids provides satisfactory analgesia with less intraoperative hypotension for spinal anesthesia in cesarean section Qiu MT, Lin FQ, Fu SK (...) , Zhang HB, Li HH, Zhang LM, Li Q CRD summary The review concluded that low dose bupivacaine combined with opioids should be considered the preferred drug combination for spinal anaesthesia in caesarean section. Shortcomings in the review included probable language bias and unsupported indirect comparisons between some of the treatment options. The authors' conclusions may not be reliable. Authors' objectives To compare low dose bupivacaine with or without opioids and high dose bupivacaine for spinal

DARE.2012

89. Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing minor surgery: a meta-analysis of randomized trials

Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing minor surgery: a meta-analysis of randomized trials Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing minor surgery: a meta-analysis of randomized trials Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing minor surgery: a meta-analysis of randomized trials Popping DM, Elia N, Marret E, Wenk M, Tramr MR CRD (...) summary This review found that the use of morphine added to intrathecally-administered bupivacaine local anaesthetic was associated with analgesic (pain relief) benefits for minor surgery but increased adverse events. The review was generally well conducted and the authors' conclusions are likely to be reliable. Authors' objectives To evaluate the effectiveness of opioids added to intrathecally-administered local anaesthetic in patients undergoing minor surgery. Searching MEDLINE, EMBASE, the Cochrane

DARE.2012

90. Streamed video clips to reduce anxiety in children during inhaled induction of anesthesia

Streamed video clips to reduce anxiety in children during inhaled induction of anesthesia 23051880 2012 10 24 2013 01 01 2012 10 24 1526-7598 115 5 2012 Nov Anesthesia and analgesia Anesth. Analg. Streamed video clips to reduce anxiety in children during inhaled induction of anesthesia. 1162-7 10.1213/ANE.0b013e31824d5224 Anesthesia induction in children is frequently achieved by inhalation of nitrous oxide and sevoflurane. Pediatric anesthesiologists commonly use distraction techniques (...) ambulatory surgery. Children (control = 47, video = 42) between 2 and 10 years old undergoing ambulatory surgery were randomly assigned to a video distraction or control group. In the video distraction group a video clip of the child's preference was played during induction, and the control group received traditional distraction methods during induction. The modified Yale Preoperative Anxiety Scale was used to assess the children's anxiety before and during the process of receiving inhalation anesthetics

EvidenceUpdates2012

91. Cartoon distraction alleviates anxiety in children during induction of anesthesia

Cartoon distraction alleviates anxiety in children during induction of anesthesia 23011563 2012 10 24 2013 01 01 2012 10 24 1526-7598 115 5 2012 Nov Anesthesia and analgesia Anesth. Analg. Cartoon distraction alleviates anxiety in children during induction of anesthesia. 1168-73 10.1213/ANE.0b013e31824fb469 We performed this study to determine the beneficial effects of viewing an animated cartoon and playing with a favorite toy on preoperative anxiety in children aged 3 to 7 years (...) in the operating room before anesthesia induction. One hundred thirty children aged 3 to 7 years with ASA physical status I or II were enrolled. Subjects were randomly assigned to 1 of 3 groups: group 1 (control), group 2 (toy), and group 3 (animated cartoon). The children in group 2 were asked to bring their favorite toy and were allowed to play with it until anesthesia induction. The children in group 3 watched their selected animated cartoon until anesthesia induction. Children's preoperative anxiety

EvidenceUpdates2012

92. Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function

Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function Conrick-Martin I, Kell MR (...) , Buggy DJ CRD summary Compared to general anaesthesia, epidural and spinal anaesthesia did not appear to significantly affect postoperative natural killer T lymphocyte function; these conclusions were not definitive due to significant differences between the included studies. Weaknesses in the conduct and reporting of the review, substantial differences between studies and their limited number and size mean that these conclusions may not be reliable. Authors' objectives To compare the effect

DARE.2012

93. Articaine is superior to lidocaine in providing pulpal anesthesia

Articaine is superior to lidocaine in providing pulpal anesthesia Articaine is superior to lidocaine in providing pulpal anesthesia ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Take advantage of endorsed, discounted business products Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Make a difference with dentistry's premier charitable organization Purchase ADA products (...) is superior to lidocaine in providing pulpal anesthesia L. Virginia Powell DMD, GPR . Overview Systematic Review Conclusion Articaine provides a higher rate of anesthetic success in anesthetizing pulpal tissues than does lidocaine, although the method of administration used and the patient’s pulpal status may diminish this effect. Critical Summary Assessment Data from a randomized clinical provided evidence of the superior anesthetic qualities of 4 percent articaine compared with those of 2 percent

ADA Center for Evidence-Based Dentistry2012

94. Articaine is superior to lidocaine in providing pulpal anesthesia

Articaine is superior to lidocaine in providing pulpal anesthesia Articaine is superior to lidocaine in providing pulpal anesthesia ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Make a difference with dentistry's premier charitable organization Take advantage of endorsed, discounted business products Purchase ADA products (...) is superior to lidocaine in providing pulpal anesthesia L. Virginia Powell DMD, GPR . Overview Systematic Review Conclusion Articaine provides a higher rate of anesthetic success in anesthetizing pulpal tissues than does lidocaine, although the method of administration used and the patient’s pulpal status may diminish this effect. Critical Summary Assessment Data from a randomized clinical provided evidence of the superior anesthetic qualities of 4 percent articaine compared with those of 2 percent

ADA Center for Evidence-Based Dentistry2012

95. The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia

The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia UTCAT2287, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Reduction Of The Adverse Effects Of Ketamine When Combined With Midazolam During Anesthesia Clinical Question In the anesthetized patient, does the combination of ketamine (Ketalar) with midazolam (Versed) reduce the adverse effects (hallucinations) produced (...) (including the those of the oral surgeon or pediatric dentist) with special anesthetic needs. Knowledge of the adverse effects of ketamine as an anesthetic, as compared to its effects when combined with midazolam would be beneficial when considering anesthetic agents for patients during dental treatment. Specialty/Discipline (General Dentistry) (Oral Surgery) (Pediatric Dentistry) Keywords Ketamine, Midazolam, Ketalar, Versed, adverse effects ID# 2287 Date of submission: 04/19/2012 E-mail Shariff

UTHSCSA Dental School CAT Library2012

96. Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion.

Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion. UTCAT2186, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Induced Hypotensive Anesthesia During a Le Fort Osteotomy Decreases the Need for a Blood Transfusion Clinical Question In an otherwise healthy patient undergoing a Le Fort Osteotomy, will hypotensive anesthesia compared to normotensive anesthesia decrease (...) the need for a blood transfusion? Clinical Bottom Line Hypotensive anesthesia is superior to normotensive anesthesia in reducing blood loss during a Le Fort Osteotomy, thus decreasing the need for a blood transfusion. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Choi/2008 Studies of patients with intentional hypotension during orthognathic surgery Systematic Review Key results 48 articles, with 22

UTHSCSA Dental School CAT Library2012

97. Periarticular Local Anesthesia does not Improve Pain or Mobility after THA

Periarticular Local Anesthesia does not Improve Pain or Mobility after THA 22270468 2012 06 07 2012 08 17 2015 01 28 1528-1132 470 7 2012 Jul Clinical orthopaedics and related research Clin. Orthop. Relat. Res. Periarticular local anesthesia does not improve pain or mobility after THA. 1958-65 10.1007/s11999-012-2241-7 Periarticular infiltration of local anesthetic, NSAIDs, and adrenaline have been reported to reduce postoperative pain, improve mobility, and reduce hospital stay for patients (...) having THAs, but available studies have not determined whether local anesthetic infiltration alone achieves similar improvements. We therefore asked whether periarticular injection of a local anesthetic during THA reduced postoperative pain and opioid requirements and improved postoperative mobility. We randomized 96 patients to either treatment (n = 50) or control groups (n = 46). Before wound closure, the treatment group received local infiltration of 160 mL of levobupivacaine with adrenaline

EvidenceUpdates2012 Full Text: Link to full Text with Trip Pro

98. Utilization of anesthesia services during outpatient endoscopies and colonoscopies and associated spending in 2003-2009.

Utilization of anesthesia services during outpatient endoscopies and colonoscopies and associated spending in 2003-2009. CONTEXT: The frequency with which anesthesiologists or nurse anesthetists provide sedation for gastrointestinal endoscopies, especially for low-risk patients, is poorly understood and controversial. OBJECTIVE: To quantify temporal comparisons and regional variation in the use of and payment for gastroenterology anesthesia services. DESIGN, SETTING, AND PATIENTS (...) : A retrospective analysis of claims data for a 5% representative sample of Medicare fee-for-service patients (1.1 million adults) and a sample of 5.5 million commercially insured patients between 2003 and 2009. MAIN OUTCOME MEASURES: Total number of upper gastrointestinal endoscopies and colonoscopies, proportion of gastroenterology procedures with associated anesthesia claims, payments for gastroenterology anesthesia services, and proportion of services and spending for gastroenterology anesthesia delivered

JAMA2012

99. Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial

Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial 21971743 2011 11 18 2012 06 12 2013 11 21 1496-8975 58 12 2011 Dec Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for Cesarean delivery on fluid and ephedrine requirement; a randomized trial. 1083-9 (...) 10.1007/s12630-011-9593-4 Patient position after spinal anesthesia has had variable effects on blood pressure and ephedrine requirements. The aim of this study was to determine the effects that sitting the patient up for five minutes after spinal anesthesia would have on intraoperative fluid and ephedrine requirements. The study included 120 women at term gestation who were scheduled for Cesarean delivery under spinal anesthesia. After anesthetic administration, the women were randomized either to sit

EvidenceUpdates2012

100. Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45

Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45 21596878 2011 09 28 2012 07 16 2014 11 20 1526-7598 113 4 2011 Oct Anesthesia and analgesia Anesth. Analg. Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45. 778-83 10.1213/ANE.0b013e31821f950e Surgery, general anesthesia, and related events have been implicated to promote (...) cancer proliferation. We investigated the incidence of cancer within 5 years after surgery in relation to duration of anesthesia (T(ANESTH)) and also by time with bispectral index (BIS) under 45 (T(BIS<45)) serving as a proxy for more profound anesthesia exposure. New malignant diagnoses after surgery under sevoflurane anesthesia were obtained in a prospective cohort of 2972 BIS-monitored patients without any clinically diagnosed malignant disease at the time of index surgery. The risk of cancer

EvidenceUpdates2012