Latest & greatest articles for anesthesia

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This page lists the very latest high quality evidence on anesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anesthesia

Clinical anesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of anesthesia:

  • Local and Regional
  • General
  • Sedation

Anesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of anesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of anesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of anesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in anesthesia and the advancements in anesthesia practise by searching Trip.

Top results for anesthesia

21. Efficacy of local dexmedetomidine add-on for spermatic cord block anesthesia in patients undergoing intrascrotal surgeries: randomized controlled multicenter clinical trial

Efficacy of local dexmedetomidine add-on for spermatic cord block anesthesia in patients undergoing intrascrotal surgeries: randomized controlled multicenter clinical trial 29184438 2017 12 19 1178-7090 10 2017 Journal of pain research J Pain Res Efficacy of local dexmedetomidine add-on for spermatic cord block anesthesia in patients undergoing intrascrotal surgeries: randomized controlled multicenter clinical trial. 2621-2628 10.2147/JPR.S145305 The objective of this study was to evaluate (...) the effect of adding dexmedetomidine (DEX) to bupivacaine on the quality of spermatic cord block anesthesia and postoperative analgesia. This is a randomized, double-blind study. This study was performed in an educational and research hospital. One hundred twenty adult males were scheduled for intrascrotal surgeries. Patients were divided into two groups: group B received 10 mL of bupivacaine 0.25% for spermatic cord block and intravenous 50 µg of DEX and group BD received 10 mL of bupivacaine 0.25

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

22. Anesthesia Assistance in Outpatient Colonoscopy and Risk of Aspiration Pneumonia, Bowel Perforation, and Splenic Injury

Anesthesia Assistance in Outpatient Colonoscopy and Risk of Aspiration Pneumonia, Bowel Perforation, and Splenic Injury 28865733 2017 12 23 1528-0012 154 1 2018 Jan Gastroenterology Gastroenterology Anesthesia Assistance in Outpatient Colonoscopy and Risk of Aspiration Pneumonia, Bowel Perforation, and Splenic Injury. 77-85.e3 S0016-5085(17)36076-6 10.1053/j.gastro.2017.08.043 The increase in use of anesthesia assistance (AA) to achieve deep sedation with propofol during colonoscopy has (...) , Toronto, Ontario; University of Toronto, Ontario, Canada. Tinmouth Jill J Sunnybrook Research Institute, Toronto, Ontario, Canada; Prevention & Cancer Control, Cancer Care Ontario, Toronto, Ontario; Department of Medicine, University of Toronto, Ontario, Canada. Electronic address: Jill.Tinmouth@sunnybrook.ca. eng Journal Article 2017 09 01 United States Gastroenterology 0374630 0016-5085 Anesthesia Colonoscopy Complications Propofol 2017 02 27 2017 08 21 2017 08 23 2017 9 4 6 0 2017 9 4 6 0 2017 9 4

EvidenceUpdates2018

23. Association Between Handover of Anesthesia Care and Adverse Postoperative Outcomes Among Patients Undergoing Major Surgery.

Association Between Handover of Anesthesia Care and Adverse Postoperative Outcomes Among Patients Undergoing Major Surgery. Importance: Handing over the care of a patient from one anesthesiologist to another occurs during some surgeries and might increase the risk of adverse outcomes. Objective: To assess whether complete handover of intraoperative anesthesia care is associated with higher likelihood of mortality or major complications compared with no handover of care. Design, Setting (...) , and Participants: A retrospective population-based cohort study (April 1, 2009-March 31, 2015 set in the Canadian province of Ontario) of adult patients aged 18 years and older undergoing major surgeries expected to last at least 2 hours and requiring a hospital stay of at least 1 night. Exposure: Complete intraoperative handover of anesthesia care from one physician anesthesiologist to another compared with no handover of anesthesia care. Main Outcomes and Measures: The primary outcome was a composite of all

JAMA2018

24. A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture

A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture 29160002 2017 12 26 1553-2712 2017 Nov 20 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture. 10.1111/acem.13351 Lumbar punctures (LPs) are commonly performed in febrile infants to evaluate (...) for meningitis, and local anesthesia increases the likelihood of LP success. Traditional methods of local anesthesia require injection that may be painful or topical application that is not effective immediately. Recent advances in needle-free jet injection may offer a rapid alternative to these modalities. We compared a needle-free jet-injection system (J-Tip) with 1% buffered lidocaine to topical anesthetic (TA) cream for local anesthesia in infant LPs. This was a single-center randomized double-blind

EvidenceUpdates2018

25. Nitrous oxide added at the end of isoflurane anesthesia hastens early recovery without increasing the risk for postoperative nausea and vomiting: a randomized clinical trial

Nitrous oxide added at the end of isoflurane anesthesia hastens early recovery without increasing the risk for postoperative nausea and vomiting: a randomized clinical trial 29150782 2018 01 13 1496-8975 65 2 2018 Feb Canadian journal of anaesthesia = Journal canadien d'anesthesie Can J Anaesth Nitrous oxide added at the end of isoflurane anesthesia hastens early recovery without increasing the risk for postoperative nausea and vomiting: a randomized clinical trial. 162-169 10.1007/s12630-017 (...) -1013-y Nitrous oxide (N2O) has been reported to increase the risk of postoperative nausea and vomiting (PONV) in a dose-dependent manner. We investigated the effect of adding N2O at the end of isoflurane inhalational anesthesia on the recovery and incidence of PONV. Our hypothesis was that N2O would reduce the time to early recovery without increasing the incidence of PONV. After obtaining ethics committee approval and written informed consent, 100 women at American Society of Anesthesiologists

EvidenceUpdates2018

26. Evidence Unclear on Effectiveness of Palatal Anesthesia in Controlling Pain and Improving Behavior of Pediatric Patients

Evidence Unclear on Effectiveness of Palatal Anesthesia in Controlling Pain and Improving Behavior of Pediatric Patients UTCAT3298, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Evidence Unclear on Effectiveness of Palatal Anesthesia in Controlling Pain and Improving Behavior of Pediatric Patients Clinical Question For children that need a dental extraction or stainless-steel crown (SSC) for primary maxillary molars (...) due to dental caries, will buccal and palatal lidocaine anesthesia, as compared to buccal lidocaine anesthesia only, improve their behavior and increase compliance in the dental chair during procedure? Clinical Bottom Line In pediatric patients, the effectiveness of buccal and palatal anesthesia, as compared to buccal anesthesia only, in controlling pain, improving behavior, and increasing compliance in the dental chair is not clearly supported by literature. Best Evidence (you may view more info

UTHSCSA Dental School CAT Library2017

27. Peripheral Nerve Block as a Supplement to Light or Deep General Anesthesia in Elderly Patients Receiving Total Hip Arthroplasty: A Prospective Randomized Study

Peripheral Nerve Block as a Supplement to Light or Deep General Anesthesia in Elderly Patients Receiving Total Hip Arthroplasty: A Prospective Randomized Study 28383293 2017 11 07 1536-5409 33 12 2017 Dec The Clinical journal of pain Clin J Pain Peripheral Nerve Block as a Supplement to Light or Deep General Anesthesia in Elderly Patients Receiving Total Hip Arthroplasty: A Prospective Randomized Study. 1053-1059 10.1097/AJP.0000000000000502 Peripheral nerve block combined with general (...) anesthesia is a preferable anesthesia method for elderly patients receiving hip arthroplasty. The depth of sedation may influence patient recovery. Therefore, we investigated the influence of peripheral nerve blockade and different intraoperative sedation levels on the short-term recovery of elderly patients receiving total hip arthroplasty. Patients aged 65 years and older undergoing total hip arthroplasty were randomized into 3 groups: a general anesthesia without lumbosacral plexus block group, and 2

EvidenceUpdates2017

28. An investigation into the effect of depth of anesthesia on postoperative pain in laparoscopic cholecystectomy surgery: a double-blind clinical trial

An investigation into the effect of depth of anesthesia on postoperative pain in laparoscopic cholecystectomy surgery: a double-blind clinical trial 29026334 2017 12 19 1178-7090 10 2017 Journal of pain research J Pain Res An investigation into the effect of depth of anesthesia on postoperative pain in laparoscopic cholecystectomy surgery: a double-blind clinical trial. 2311-2317 10.2147/JPR.S142186 Some studies have shown that deeper anesthesia is more effective on postoperative analgesia and (...) reduces the need for sedative drugs. This study sought to investigate the effect of depth of anesthesia on postoperative pain in laparoscopic cholecystectomy. In this double-blind clinical trial, 60 patients undergoing laparoscopic cholecystectomy were randomly divided into two groups: low bispectral index (L-BIS=35-44) and high bispectral index (H-BIS=45-55). Anesthesia protocol was the same for both groups (propofol and remifentanil). The pain intensity (at rest and during cough) was evaluated based

EvidenceUpdates2017 Full Text: Link to full Text with Trip Pro

29. Intermittent Catheterization for Post-Operative Patients with Spinal Anesthesia: Guidelines

Intermittent Catheterization for Post-Operative Patients with Spinal Anesthesia: Guidelines Intermittent Catheterization for Post-Operative Patients with Spinal Anesthesia: Guidelines | CADTH.ca Find the information you need Intermittent Catheterization for Post-Operative Patients with Spinal Anesthesia: Guidelines Intermittent Catheterization for Post-Operative Patients with Spinal Anesthesia: Guidelines Published on: November 28, 2017 Project Number: RB1171-000 Product Line: Research Type (...) : Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What are the evidence-based guidelines regarding the use of in-and-out or intermittent catheters to prevent urinary retention in post-operative patients who have received spinal anesthesia? Key Message No relevant literature was identified regarding the use of in-and-out or intermittent catheters to prevent urinary retention in post-operative patients who have received spinal anesthesia. Tags kidney, anesthesia

Canadian Agency for Drugs and Technologies in Health - Rapid Review2017

30. Effect of Xenon Anesthesia Compared to Sevoflurane and Total Intravenous Anesthesia for Coronary Artery Bypass Graft Surgery on Postoperative Cardiac Troponin Release: An International, Multicenter, Phase 3, Single-blinded, Randomized Noninferiority Trial

Effect of Xenon Anesthesia Compared to Sevoflurane and Total Intravenous Anesthesia for Coronary Artery Bypass Graft Surgery on Postoperative Cardiac Troponin Release: An International, Multicenter, Phase 3, Single-blinded, Randomized Noninferiority Trial 28872484 2017 09 05 2017 11 14 1528-1175 127 6 2017 Dec Anesthesiology Anesthesiology Effect of Xenon Anesthesia Compared to Sevoflurane and Total Intravenous Anesthesia for Coronary Artery Bypass Graft Surgery on Postoperative Cardiac (...) Troponin Release: An International, Multicenter, Phase 3, Single-blinded, Randomized Noninferiority Trial. 918-933 10.1097/ALN.0000000000001873 Ischemic myocardial damage accompanying coronary artery bypass graft surgery remains a clinical challenge. We investigated whether xenon anesthesia could limit myocardial damage in coronary artery bypass graft surgery patients, as has been reported for animal ischemia models. In 17 university hospitals in France, Germany, Italy, and The Netherlands, low-risk

EvidenceUpdates2017

31. Ankle Block vs Single-Shot Popliteal Fossa Block as Primary Anesthesia for Forefoot Operative Procedures: Prospective, Randomized Comparison

Ankle Block vs Single-Shot Popliteal Fossa Block as Primary Anesthesia for Forefoot Operative Procedures: Prospective, Randomized Comparison 28814096 2017 08 17 2017 08 17 1944-7876 2017 Aug 01 Foot & ankle international Foot Ankle Int Ankle Block vs Single-Shot Popliteal Fossa Block as Primary Anesthesia for Forefoot Operative Procedures: Prospective, Randomized Comparison. 1071100717723132 10.1177/1071100717723132 Postoperative pain is often difficult to control with oral medications (...) , requiring large doses of opioid analgesia. Regional anesthesia may be used for primary anesthesia, reducing the need for general anesthetic and postoperative pain medication requirements in the immediate postoperative period. The purpose of this study was to compare the analgesic effects of an ankle block (AB) to a single-shot popliteal fossa block (PFB) for patients undergoing orthopedic forefoot procedures. All patients having elective outpatient orthopedic forefoot procedures were invited

EvidenceUpdates2017

32. Babies Can Safely Breastfeed After Their Mothers Have Local Anesthesia for a Dental Procedure

Babies Can Safely Breastfeed After Their Mothers Have Local Anesthesia for a Dental Procedure UTCAT3266, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Babies Can Safely Breastfeed After Their Mothers Have Local Anesthesia for a Dental Procedure Clinical Question Are babies whose mothers have local anesthesia for dental procedures at increased risk for ingesting the anesthetic? Clinical Bottom Line It is safe (...) for a mother to breastfeed after having local anesthesia for a dental procedure. This is based on a clinical study showing that the amount of lidocaine in the breast milk was low. Local anesthesia is widely used in all general dental practices and accepted by patients. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Giuliani/2001 7 nursing mothers between the ages of 23-39 Noncontrolled clinical study Key

UTHSCSA Dental School CAT Library2017

33. Intraoperative "Analgesia Nociception Index"-Guided Fentanyl Administration During Sevoflurane Anesthesia in Lumbar Discectomy and Laminectomy: A Randomized Clinical Trial

Intraoperative "Analgesia Nociception Index"-Guided Fentanyl Administration During Sevoflurane Anesthesia in Lumbar Discectomy and Laminectomy: A Randomized Clinical Trial 28598927 2017 06 09 2017 08 08 2017 08 08 1526-7598 125 1 2017 Jul Anesthesia and analgesia Anesth. Analg. Intraoperative "Analgesia Nociception Index"-Guided Fentanyl Administration During Sevoflurane Anesthesia in Lumbar Discectomy and Laminectomy: A Randomized Clinical Trial. 81-90 10.1213/ANE.0000000000001984 (...) The "Analgesia Nociception Index" (ANI; MetroDoloris Medical Systems, Lille, France) is a proposed noninvasive guide to analgesia derived from an electrocardiogram trace. ANI is scaled from 0 to 100; with previous studies suggesting that values ≥50 can indicate adequate analgesia. This clinical trial was designed to investigate the effect of intraoperative ANI-guided fentanyl administration on postoperative pain, under anesthetic conditions optimized for ANI functioning. Fifty patients aged 18 to 75 years

EvidenceUpdates2017

34. General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke)

General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke) 28522637 2017 05 19 2017 05 23 1524-4628 48 6 2017 Jun Stroke Stroke General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke). 1601-1607 10.1161/STROKEAHA.117.016554 Retrospective studies have found that patients receiving general anesthesia for endovascular treatment (...) in acute ischemic stroke have worse neurological outcome compared with patients receiving conscious sedation. In this prospective randomized single-center study, we investigated the impact of anesthesia technique on neurological outcome in acute ischemic stroke patients. Ninety patients receiving endovascular treatment for acute ischemic stroke in 2013 to 2016 were included and randomized to general anesthesia or conscious sedation. Difference in neurological outcome at 3 months, measured as modified

EvidenceUpdates2017

35. Safety Aspects of Postanesthesia Care Unit Discharge without Motor Function Assessment after Spinal Anesthesia: A Randomized, Multicenter, Semiblinded, Noninferiority, Controlled Trial

Safety Aspects of Postanesthesia Care Unit Discharge without Motor Function Assessment after Spinal Anesthesia: A Randomized, Multicenter, Semiblinded, Noninferiority, Controlled Trial 28511195 2017 05 16 2017 05 16 1528-1175 126 6 2017 Jun Anesthesiology Anesthesiology Safety Aspects of Postanesthesia Care Unit Discharge without Motor Function Assessment after Spinal Anesthesia: A Randomized, Multicenter, Semiblinded, Noninferiority, Controlled Trial. 1043-1052 10.1097/ALN.0000000000001629 (...) Postanesthesia care unit (PACU) discharge without observation of lower limb motor function after spinal anesthesia has been suggested to significantly reduce PACU stay and enhance resource optimization and early rehabilitation but without enough data to allow clinical recommendations. A multicenter, semiblinded, noninferiority randomized controlled trial of discharge from the PACU with or without assessment of lower limb motor function after elective total hip or knee arthroplasty under spinal anesthesia

EvidenceUpdates2017

36. Intraoperative Completion Studies, Local Anesthesia, and Antiplatelet Medication Are Associated With Lower Risk in Carotid Endarterectomy

Intraoperative Completion Studies, Local Anesthesia, and Antiplatelet Medication Are Associated With Lower Risk in Carotid Endarterectomy 28283609 2017 03 11 2017 03 28 1524-4628 48 4 2017 Apr Stroke Stroke Intraoperative Completion Studies, Local Anesthesia, and Antiplatelet Medication Are Associated With Lower Risk in Carotid Endarterectomy. 955-962 10.1161/STROKEAHA.116.014869 In Germany, all surgical and endovascular procedures on the carotid bifurcation must be documented in a statutory (...) were secondary outcomes. Adjusted relative risks (RRs) were assessed by multivariable multilevel regression analyses. The primary outcome occurred in 1.8% of patients, with a rate of 1.4% in asymptomatic and 2.5% in symptomatic patients, respectively. In the multivariable analysis, lower risks of stroke or death were independently associated with local anesthesia (versus general anesthesia: RR, 0.85; 95% confidence interval [CI], 0.75-0.95), carotid endarterectomy with patch plasty compared

EvidenceUpdates2017

37. Liposomal Bupivacaine May Prove to Provide Adequate Long-Term Local Anesthesia

Liposomal Bupivacaine May Prove to Provide Adequate Long-Term Local Anesthesia UTCAT3208, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Liposomal Bupivacaine May Prove to Provide Adequate Long-Term Local Anesthesia Clinical Question Is liposomal bupivacaine (Exparel) effective in providing extended local anesthesia and reducing post-operative opioid use in a variety of dental procedures? Clinical Bottom Line (...) For patients receiving endodontic care or third molar extractions, there is not enough evidence to support the conclusion that liposomal bupivacaine is any more effective than other anesthesia medications. This is supported by a randomized double-blinded study in which buccal infiltration of liposomal bupivacaine was shown to not achieve clinically relevant levels of anesthesia for prolonged periods of time. A systematic review of liposomal bupivacaine showed inconclusive evidence to support that liposomal

UTHSCSA Dental School CAT Library2017

38. The Influence of Oral Ginger before Operation on Nausea and Vomiting after Cataract Surgery under General Anesthesia: A double-blind placebo-controlled randomized clinical trial.

The Influence of Oral Ginger before Operation on Nausea and Vomiting after Cataract Surgery under General Anesthesia: A double-blind placebo-controlled randomized clinical trial. 28243400 2017 02 28 2017 03 02 9 1 2017 Jan Electronic physician Electron Physician The Influence of Oral Ginger before Operation on Nausea and Vomiting after Cataract Surgery under General Anesthesia: A double-blind placebo-controlled randomized clinical trial. 3508-3514 10.19082/3508 According to Iranian traditional (...) medicine, using safe ginger may contribute to taking less chemical medicines and result in fewer side effects. To determine the influence of using ginger before operation on nausea and vomiting, after cataract surgery under general anesthesia. This study was a double-blind placebo-controlled randomized clinical trial conducted at Kurdistan University of Medical Sciences in 2015. 122 candidates of cataract surgery were randomly allocated in three groups. The first group received a ginger capsule

Electronic physician2017 Full Text: Link to full Text with Trip Pro

39. Comparison of Regional vs. General Anesthesia for Surgical Repair of Open-Globe Injuries at a University Referral Center

Comparison of Regional vs. General Anesthesia for Surgical Repair of Open-Globe Injuries at a University Referral Center 28944317 2018 11 13 2468-7219 1 3 2017 May-Jun Ophthalmology. Retina Ophthalmol Retina Comparison of Regional vs. General Anesthesia for Surgical Repair of Open-Globe Injuries at a University Referral Center. 188-191 10.1016/j.oret.2016.11.006 This study compares the clinical features and physician selection of either Regional Anesthesia (peribulbar or retrobulbar block (...) ) with Monitored Anesthesia Care (RA-MAC) or General Anesthesia (GA) for open globe injury repair. A non-randomized, comparative, retrospective case series at a University Referral Center. All adult repairable open globe injuries receiving primary repair between January 1st, 2004 and December 31st, 2014 (11 years). Exclusion criteria were patients less than 18 years of age and those treated with primary enucleation. Data was gathered via retrospective chart review. Data collected from each patient was age

Ophthalmology retina2017 Full Text: Link to full Text with Trip Pro

40. Palliative radiation therapy for superior vena cava syndrome in metastatic Wilms tumor using 10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patient—a teaching case

Palliative radiation therapy for superior vena cava syndrome in metastatic Wilms tumor using 10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patient—a teaching case 28740919 2018 11 13 2452-1094 2 1 2017 Jan-Mar Advances in radiation oncology Adv Radiat Oncol Palliative radiation therapy for superior vena cava syndrome in metastatic Wilms tumor using 10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patient-a teaching case. 101-104 10.1016/j.adro.2016.12.007

Advances in radiation oncology2017 Full Text: Link to full Text with Trip Pro