Latest & greatest articles for anesthesia

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This page lists the very latest high quality evidence on anesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anesthesia

Clinical anesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of anesthesia:

  • Local and Regional
  • General
  • Sedation

Anesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of anesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of anesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of anesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in anesthesia and the advancements in anesthesia practise by searching Trip.

Top results for anesthesia

181. Comparison of bupivacaine and 2-chloroprocaine for spinal anesthesia for outpatient surgery: a double-blind randomized trial (PubMed)

Comparison of bupivacaine and 2-chloroprocaine for spinal anesthesia for outpatient surgery: a double-blind randomized trial We have always been searching for the ideal local anesthetic for outpatient spinal anesthesia. Lidocaine has been associated with a high incidence of transient neurological symptoms, and bupivacaine produces sensory and motor blocks of long duration. Preservative-free 2-chloroprocaine (2-CP) seems to be a promising alternative, being a short-acting agent of increasing (...) popularity in recent years. This study was designed to compare 2-CP with bupivacaine for spinal anesthesia in an elective ambulatory setting.A total of 106 patients were enrolled in this randomized double-blind study. Spinal anesthesia was achieved with 0.75% hyperbaric bupivacaine 7.5 mg (n = 53) or 2% preservative-free 2-CP 40 mg (n = 53). The primary endpoint for the study was the time until reaching eligibility for discharge. Secondary outcomes included the duration of the sensory and motor blocks

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2011 EvidenceUpdates Controlled trial quality: predicted high

182. Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery (PubMed)

Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery A combination of general anesthesia (GA) with thoracic epidural anesthesia (TEA) may have a beneficial effect on clinical outcomes after cardiac surgery. We have performed a meta-analysis to compare mortality and cardiac, respiratory, and neurologic complications in patients undergoing cardiac surgery with GA alone or a combination of GA with TEA.Randomized studies comparing outcomes in patients

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2011 EvidenceUpdates

183. Low-dose, low-concentration levobupivacaine plus fentanyl selective spinal anesthesia for knee arthroscopy: a dose finding study (PubMed)

Low-dose, low-concentration levobupivacaine plus fentanyl selective spinal anesthesia for knee arthroscopy: a dose finding study Selective sensory spinal anesthesia preserves lower limb motor function and thus facilitates postanesthesia care unit (PACU) bypass and reduces ambulation recovery time.We compared the ambulation time and PACU bypass rate after using 3 low-dose, low-concentration levobupivacaine-fentanyl spinal solutions (5, 4, and 3 mg + 10 μg) in a double-blind study consisting (...) anesthesia with the shortest time to ambulation and the highest PACU bypass rate.

2011 EvidenceUpdates Controlled trial quality: uncertain

184. Thoracic epidural anesthesia improves early outcomes in patients undergoing off-pump coronary artery bypass surgery: a prospective, randomized, controlled trial (PubMed)

Thoracic epidural anesthesia improves early outcomes in patients undergoing off-pump coronary artery bypass surgery: a prospective, randomized, controlled trial The aim of this two-center, open, randomized, controlled trial was to evaluate the impact of thoracic epidural anesthesia on early clinical outcomes in patients undergoing off-pump coronary artery bypass surgery.Two hundred and twenty-six patients were randomized to either general anesthesia plus epidural (GAE) (n = 109) or general (...) anesthesia only (GA) (n = 117). The primary outcome was length of postoperative hospital stay. Secondary outcomes were: arrhythmia, inotropic support, intubation time, perioperative myocardial infarction, neurologic events, intensive care stay, pain scores, and analgesia requirement.Baseline characteristics were similar in the two groups. One patient died in the GAE group. Median postoperative stay was significantly reduced in the GAE, compared with the GA, group (5 days, interquartile range [5-6] vs. 6

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2011 EvidenceUpdates Controlled trial quality: predicted high

185. Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar

Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted (...) over lidocaine for dental local anesthesia of the first molar Arthur Jeske DMD, PhD; James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion Articaine 4%, when compared to Lidocaine 2%, provides more effective local anesthesia in the first molar region for routine dental procedures while demonstrating a similar short-term adverse effect profile. Critical Summary Assessment An appropriately designed and which followed a clear protocol for locating and assessing relevant randomized

2011 ADA Center for Evidence-Based Dentistry

186. Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar

Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted (...) over lidocaine for dental local anesthesia of the first molar Arthur Jeske DMD, PhD; James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion Articaine 4%, when compared to Lidocaine 2%, provides more effective local anesthesia in the first molar region for routine dental procedures while demonstrating a similar short-term adverse effect profile. Critical Summary Assessment An appropriately designed and which followed a clear protocol for locating and assessing relevant randomized

2011 ADA Center for Evidence-Based Dentistry

187. Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar

Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar Limited evidence favors articaine over lidocaine for dental local anesthesia of the first molar ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted (...) over lidocaine for dental local anesthesia of the first molar Arthur Jeske DMD, PhD; James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion Articaine 4%, when compared to Lidocaine 2%, provides more effective local anesthesia in the first molar region for routine dental procedures while demonstrating a similar short-term adverse effect profile. Critical Summary Assessment An appropriately designed and which followed a clear protocol for locating and assessing relevant randomized

2011 ADA Center for Evidence-Based Dentistry

188. Thoracic epidural anesthesia for cardiac surgery: a randomized trial (PubMed)

Thoracic epidural anesthesia for cardiac surgery: a randomized trial The addition of thoracic epidural anesthesia (TEA) to general anesthesia (GA) during cardiac surgery may have a beneficial effect on clinical outcomes. TEA in cardiac surgery, however, is controversial because the insertion of an epidural catheter in patients requiring full heparinization for cardiopulmonary bypass may lead to an epidural hematoma. The clinical effects of fast-track GA plus TEA were compared with those (...) (P = 0.23). At 1 yr follow-up, survival free from myocardial infarction, pulmonary complications, renal failure, and stroke was 84.6% in the TEA group and 87.2% in the GA group (P = 0.42). Postoperative pain scores were low in both groups.This study was unable to demonstrate a clinically relevant benefit of TEA on the frequency of major complications after elective cardiac surgery, compared with fast-track cardiac anesthesia without epidural anesthesia. Given the potentially devastating

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2011 EvidenceUpdates Controlled trial quality: predicted high

189. The dose-dependent effects of phenylephrine for elective cesarean delivery under spinal anesthesia (PubMed)

The dose-dependent effects of phenylephrine for elective cesarean delivery under spinal anesthesia Hypotension is the most common serious side effect of spinal anesthesia for cesarean delivery. There has been a move recently toward the use of phenylephrine as a vasopressor infusion to improve maternal cardiovascular stability and fetal outcome. Although it seems safe in the elective setting, there have been concerns about its propensity for causing an increase in afterload and a baroreceptor (...) to maintain maternal baseline systolic blood pressure (SBP), from induction of spinal anesthesia until delivery. The maternal cardiovascular variables recorded included heart rate (HR) and SBP. A suprasternal Doppler monitor measured CO and stroke volume, as well as measures of venous return (corrected flow time) and contractility, at baseline, and then every 5 minutes for 20 minutes after initiation of spinal anesthesia. Apgar scores and umbilical cord blood gases were recorded.SBP control

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2011 EvidenceUpdates Controlled trial quality: uncertain

190. Postoperative Analgesic Effects of Favorite Music After Cesarean Delivery Under General Anesthesia

Postoperative Analgesic Effects of Favorite Music After Cesarean Delivery Under General Anesthesia "Postoperative Analgesic Effects of Favorite Music After Cesarean Deliv" by Harsimranpreet Kaur < > > > > > Title Author Date of Graduation Spring 5-15-2011 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Torry Cobb, DHSc, MPH, PA-C Rights . Abstract Background: This systematic review was designed to evaluate the analgesic effects (...) of patient’s “favorite music.” The music was chosen by the elective cesarean section patient undergoing general anesthesia and it was played during the perioperative period. The review was designed to evaluate the evidence using GRADE and determine the effectiveness of music in reducing the overall pain and opioid usage in postoperative cesarean section patients. Method: The medical literature was exhaustively searched using the keywords listed below. The search was limited to randomized controlled trials

2011 Pacific University EBM Capstone Project

191. American College of Chest Physicians Consensus Statement on the Use of Topical Anesthesia, Analgesia, and Sedation During Flexible Bronchoscopy in Adult Patients

American College of Chest Physicians Consensus Statement on the Use of Topical Anesthesia, Analgesia, and Sedation During Flexible Bronchoscopy in Adult Patients CHEST Consensus Statement 1342 Consensus Statement Executive Summary Performing Bronchoscopy With No Sedation There is an equal safety record of sedation 1. vs no sedation in bronchoscopy, but patients’ satisfaction and procedure tol- erance are signi? cantly improved with sedation. Sedation is suggested in all patients un- 2. dergoing (...) bronchoscopy unless contra- indications exist. The extent of sedation (minimal, mod- 3. erate, deep, or general anesthesia) used during bronchoscopy can vary based on American College of Chest Physicians Consensus Statement on the Use of Topical Anesthesia, Analgesia, and Sedation During Flexible Bronchoscopy in Adult Patients Momen M. W ahidi , MD, MBA, FCCP ; Prasoon Jain , MD, FCCP ; Michael Jantz , MD, FCCP ; Pyng Lee , MD, FCCP ; G. Burkhard Mackensen , MD, PhD ; Sally Y . Barbour , PharmD ; Carla

2011 American College of Chest Physicians

192. Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts

Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts Flamer D, Peng PW CRD summary This review found that ropivacaine was effective for intravenous (...) treatments that could provide effective analgesia after tourniquet removal. Funding Not stated. Bibliographic details Flamer D, Peng PW. Intravenous regional anesthesia: a review of common local anesthetic options and the use of opioids and muscle relaxants as adjuncts. Local and Regional Anesthesia 2011; 4: 57-76 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by CRD MeSH Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Humans; Muscle Relaxants, Central

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2011 DARE.

193. Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials

Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

194. A comparison of liver function after hepatectomy with inflow occlusion between sevoflurane and propofol anesthesia (PubMed)

A comparison of liver function after hepatectomy with inflow occlusion between sevoflurane and propofol anesthesia In this study, we compared liver function tests after hepatectomy with inflow occlusion as a function of propofol versus sevoflurane anesthesia.One hundred patients undergoing elective liver resection with inflow occlusion were randomized into a sevoflurane group or a propofol group. General anesthesia was induced with 3 μg/kg fentanyl, 0.2 mg/kg cisatracurium, and target (...) -controlled infusion of propofol, set at a plasma target concentration of 4 to 6 μg/mL, or sevoflurane initially started at 8%. Anesthesia was maintained with target-controlled infusion of propofol (2-4 μg/mL) or sevoflurane (1.5%-2.5%). The primary end point was postoperative liver injury assessed by peak values of liver transaminases.Transaminase levels peaked between the first and the third postoperative day. Peak alanine aminotransferase was 504 and 571 U/L in the sevoflurane group and the propofol

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2010 EvidenceUpdates Controlled trial quality: uncertain

195. Brief reports: paravertebral block for anesthesia: a systematic review (PubMed)

Brief reports: paravertebral block for anesthesia: a systematic review The objective of this review was to assess the safety and efficacy of thoracic and lumbar paravertebral blocks (PVBs) for surgical anesthesia through a systematic review of the peer-reviewed literature. PVBs for surgical anesthesia were compared with general anesthesia (GA) or other regional anesthetic techniques.We searched literature databases including MEDLINE, EMBASE, and The Cochrane Library up to May 2008. Included (...) studies were limited to eligible randomized controlled trials. Eight randomized controlled trials were included in this review, 6 of which used PVBs for anesthesia during breast surgery, and 2 trials used PVB for anesthesia during herniorrhaphy.The ability to obtain firm conclusions was limited by the diversity of outcomes and how they were measured, which varied across studies. The PVB failure rate was not >13%, and patients were more satisfied with PVB than with GA. There was some indication

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2010 EvidenceUpdates

196. Comparison of safety and clinical and radiographic outcomes in endovascular acute stroke therapy for proximal middle cerebral artery occlusion with intubation and general anesthesia versus the nonintubated state (PubMed)

Comparison of safety and clinical and radiographic outcomes in endovascular acute stroke therapy for proximal middle cerebral artery occlusion with intubation and general anesthesia versus the nonintubated state There is considerable heterogeneity in practice patterns between sedation in the intubated state vs nonintubated state during endovascular acute stroke therapy. We sought to compare clinical and radiographic outcomes between these 2 sedation modalities.Consecutive patients with acute

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2010 EvidenceUpdates

197. Effect of thoracic epidural anesthesia with different concentrations of ropivacaine on arterial oxygenation during one-lung ventilation (PubMed)

Effect of thoracic epidural anesthesia with different concentrations of ropivacaine on arterial oxygenation during one-lung ventilation Thoracic epidural anesthesia can contribute to facilitate the fast-track approach in lung surgery. However, data regarding the effects of thoracic epidural anesthesia on oxygenation during one-lung ventilation (OLV) are scarce and contradictory. Therefore, the authors conducted a prospective, randomized, double-blinded trial in patients undergoing lung surgery (...) under spectral entropy-guided intravenous anesthesia to evaluate the effects of thoracic epidural anesthesia with different concentrations of ropivacaine on oxygenation, shunt fraction (Qs/Qt) during OLV, and maintenance doses of propofol.One hundred twenty patients scheduled for lung surgery were randomly divided into four groups to epidurally receive saline (Group S), 0.25% (Group R0.25), 0.50% (Group R0.50), and 0.75% (Group R0.75) ropivacaine. Ropivacaine was administered intraoperatively (6-8

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2010 EvidenceUpdates Controlled trial quality: uncertain

198. The ability of pleth variability index to predict the hemodynamic effects of positive end-expiratory pressure in mechanically ventilated patients under general anesthesia (PubMed)

The ability of pleth variability index to predict the hemodynamic effects of positive end-expiratory pressure in mechanically ventilated patients under general anesthesia Pleth variability index (PVI) is a new algorithm allowing automated and continuous monitoring of respiratory variations in the pulse oximetry plethysmographic waveform amplitude. PVI can predict fluid responsiveness noninvasively in mechanically ventilated patients during general anesthesia. We hypothesized that PVI could

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2010 EvidenceUpdates

199. Preload or coload for spinal anesthesia for elective Cesarean delivery: a meta-analysis (PubMed)

Preload or coload for spinal anesthesia for elective Cesarean delivery: a meta-analysis Hypotension following spinal anesthesia for Cesarean delivery is common. Fluid loading is recommended to prevent hypotension, but preload is often ineffective. In non-pregnant patients, coloading has been shown to better maintain cardiac output after spinal anesthesia. The purpose of this meta-analysis was to determine whether the timing of the fluid infusion, before (preload) or during (coload) induction (...) of spinal anesthesia for Cesarean delivery, influences the incidence of maternal hypotension or neonatal outcome.We retrieved randomized controlled trials that compared a fluid preload with coload in patients undergoing spinal anesthesia for elective Cesarean delivery. We graded the articles for quality of reporting (maximum score = 5) and recorded the incidence of hypotension, lowest blood pressure, the incidence of maternal nausea and vomiting, umbilical cord pH, and Apgar scores. We combined

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2010 EvidenceUpdates

200. Comparison of single-use and reusable metal laryngoscope blades for orotracheal intubation during rapid sequence induction of anesthesia (PubMed)

Comparison of single-use and reusable metal laryngoscope blades for orotracheal intubation during rapid sequence induction of anesthesia Single-use metal laryngoscope blades are cheaper and carry a lower risk of infection than reusable metal blades. The authors compared single-use and reusable metal blades during rapid sequence induction of anesthesia in a multicenter cluster randomized trial.One thousand seventy-two adult patients undergoing general anesthesia under emergency conditions (...) statistical significance, although the same trend was noted (6.8% vs. 11.5%, P = not significant). An investigator survey and a measure of illumination pointed that illumination might have been responsible for this result.The single-use metal blade was more efficient than a reusable metal blade in rapid sequence induction of anesthesia.

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2010 EvidenceUpdates Controlled trial quality: uncertain