Latest & greatest articles for anastrozole

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Top results for anastrozole

21. Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Al

Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Al Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex (...) ', Tamoxifen Alone or in Combination) trial Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Alone or in Combination) trial Locker GY, Mansel R, Cella D, Dobrez D, Sorensen S, Gandhi SK Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each

NHS Economic Evaluation Database.2007

22. Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis

Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis Jonat W, Gnant M, Boccardo F (...) , Kaufmann M, Rubagotti A, Zuna I, Greenwood M, Jakesz R CRD summary This review concluded that participants who changed to anastrozole after 2 to 3 years' treatment with tamoxifen had significantly fewer disease recurrences than those remaining on tamoxifen for 5 years. Survival was also significantly improved. Poor reporting of review methodology and the lack of knowledge about the quality of the trials mean that the authors' conclusions should be interpreted with caution. Authors' objectives

DARE.2006

23. Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer

Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Augustovski F, Pichon Riviere A, Alcaraz A, Bardach A, Garcia Marti S, Lopez A, Glujovsky D, Regueiro A Record Status This is a bibliographic record of a published health technology (...) assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Augustovski F, Pichon Riviere A, Alcaraz A, Bardach A, Garcia Marti S, Lopez A, Glujovsky D, Regueiro A. Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No.63. 2006 Authors' objectives This report is intended

Health Technology Assessment (HTA) Database.2006

24. Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective

Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Piskur P, Sonc M, Cufer T, Borstnar S, Mrhar A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains (...) a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study assessed the clinical and economic impact of anastrozole (AN) and tamoxifen for the treatment of postmenopausal women with hormone receptor-positive breast cancer. The authors concluded that AN could be considered a cost-effective strategy from the perspective of the Slovenian health care system. There were a few

NHS Economic Evaluation Database.2006

25. Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis

Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Rocchi A, Verma S Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined the use of anastrozole (Arimidex) in the adjuvant treatment of hormone receptor-positive (HR+), postmenopausal early breast cancer (BC) patients. Anastrozole was compared

NHS Economic Evaluation Database.2006

26. Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer

Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women (...) therapy with aromatase inhibitors or with tamoxifen in postmenopausal women with operable breast cancer. The authors concluded that exemestane after tamoxifen was more cost-effective than anastrozole or letrozole. The quality of the methodology used was satisfactory. Both the results and methods were adequately reported. As there was no head-to-head comparison of the three aromatase inhibitors, caution should be exercised when evaluating which one was the most cost-effective. Type of economic

NHS Economic Evaluation Database.2006

27. Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial

Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Moeremans K, Annemans L Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The authors compared anastrozole and tamoxifen, both alone and in combination. Dosages and further details were not provided. Type of intervention Treatment. Economic study type Cost-utility analysis. Study population The study population

NHS Economic Evaluation Database.2006

28. Anastrozole (Arimidex) - Early breast cancer in hormone receptor positive postmenopausal women who have received 2 to 3 years of adjuvant tamoxifen

Anastrozole (Arimidex) - Early breast cancer in hormone receptor positive postmenopausal women who have received 2 to 3 years of adjuvant tamoxifen

Scottish Medicines Consortium2006

29. Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial.

Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. 16084253 2005 08 08 2005 10 06 2015 06 16 1474-547X 366 9484 2005 Aug 6-12 Lancet (London, England) Lancet Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. 455-62 Tamoxifen has been (...) the standard adjuvant treatment for postmenopausal women with hormone-responsive early breast cancer for more than 20 years. However, the third-generation aromatase inhibitor anastrozole has proven efficacy and tolerability benefits compared with tamoxifen when used as initial adjuvant therapy. We investigate whether women who have received a period of adjuvant tamoxifen would benefit from being switched to anastrozole. We present a combined analysis of data from two prospective, multicentre, randomised

Lancet2005

31. Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer

Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor (...) -positive breast cancer Hillner B E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of anastrozole (1 mg) as initial adjuvant therapy for women with early-stage estrogen receptor-positive breast cancer. Type of intervention

NHS Economic Evaluation Database.2004

32. Anastrozole (Arimidex) - Postmenopausal women with oestrogen receptor positive early invasive breast cancer

Anastrozole (Arimidex) - Postmenopausal women with oestrogen receptor positive early invasive breast cancer Secretariat - Delta House 50 West Nile Street Glasgow G1 2NP Telephone 0141 225 6997 Fax 0141 248 3778 E-mail jmitchell@htbs.org.uk Chairman Professor David Lawson Scottish Medicines Consortium Anastrozole (Arimidex Ò ) No. 90/04 AstraZeneca UK Ltd Indication: Adjuvant treatment of postmenopausal women with oestrogen receptor (ER) positive early invasive breast cancer who are unable (...) to take tamoxifen because of a high risk of thromboembolism or endometrial abnormalities. Summary of Recommendation 8 February, 2004 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and ADTCs on its use in NHS Scotland. The recommendation is summarised as follows: Advice: following a full submission. Anastrozole (Arimidex ® ) is accepted for restricted use within NHS Scotland for the adjunctive treatment of early breast cancer

Scottish Medicines Consortium2004

33. Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer

Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Simons W R, Jones D, Buzdar A Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Postmenopausal women with predominantly hormone receptor-positive advanced breast cancer were given anastrozole (1 mg/day) as first-line therapy. The comparator was tamoxifen (20 mg/day). Type of intervention Treatment and secondary prevention. Economic study type Cost-utility

NHS Economic Evaluation Database.2003

34. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial.

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. 12090977 2002 07 01 2002 07 11 2015 06 16 0140-6736 359 9324 2002 Jun 22 Lancet (London, England) Lancet Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. 2131-9 (...) In the adjuvant setting, tamoxifen is the established treatment for postmenopausal women with hormone-sensitive breast cancer. However, it is associated with several side-effects including endometrial cancer and thromboembolic disorders. We aimed to compare the safety and efficacy outcomes of tamoxifen with those of anastrozole alone and the combination of anastrozole plus tamoxifen for 5 years. Participants were postmenopausal patients with invasive operable breast cancer who had completed primary therapy

Lancet2002

35. Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer

Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Wiseman L R, Adkins J C Authors' objectives To examine the use of anastrozole in the management of postmenopausal women with advanced breast cancer. Searching Medical literature published (...) since 1966 on anastrozole was identified using AdisBase, MEDLINE and EMBASE. References also identified from reference lists of published articles. Bibliographic information, including contributory data was also requested from the company developing the drug. Search terms: anastrozole, armidex, ic-d-1033, zd-1033 (all databases), breast cancer, aromatase inhibitor (AdisBase only), 120511-73-1 (MEDLINE and EMBASE only). Searches last updated 1 September 1988. Study selection Study designs

DARE.1998