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Latest & greatest articles for anaesthesia
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Clinical Anaesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of Anaesthesia:
Local and Regional
Anaesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.
Research and development in the use of Anaesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of Anaesthesia through the years has massively influences medicine and surgery today.
Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of Anaesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.
Learn more on the emerging technology in Anaesthesia and the advancements in Anaesthesia practise by searching Trip.
local anesthesia infiltration, does the warming of the cartridge pre-injection reduce the anticipated injection pain compared to using cartridges at room temperature? Clinical Bottom Line Warming of local anesthetic cartridges does not reduce pain and discomfort during intraoral infiltration injections. This is supported by a randomized controlled clinical trial that showed that children's objective and subjective reactions to warmed and room temperature injections were not statistically different (...) between the children’s reactions to the warm (W) and room temperature (RT) injections on any of the three parameters. Evidence Search ("review"[All Fields] OR "review literature as topic"[MeSH Terms] OR "systematic review"[All Fields]) AND warming[All Fields] AND ("local anaesthesia"[All Fields] OR "anesthesia, local"[MeSH Terms] OR ("anesthesia"[All Fields] AND "local"[All Fields]) OR "local anesthesia"[All Fields] OR ("local"[All Fields] AND "anesthesia"[All Fields])) Comments on The Evidence
Implication of general anaesthetic and sedation techniques in temporomandibular joint disordersÂ -Â a systematic review. The purpose of this study was to conduct a systematic review of the literature on temporomandibular joint damage directly related to general anaesthesia and sedation. We searched MEDLINE, SCOPUS and the COCHRANE Library for titles and abstracts containing terms related to the subject. The search delimiters were analytical and descriptive studies with abstracts in Spanish (...) , German, English or French, with no time limit. The search was updated in January 2015. Of the 398 articles found, 89 were duplicates and only 28 were of interest. Of these, 23 (82.14%) were case and case series reports, 4 (14.28%) were longitudinal studies and 1 (3.57%) was a cross-sectional study. General anaesthesia and sedation are risk factors for temporomandibular joint damage because of the drop in muscle tone caused by the drugs employed and because of airway management manoeuvres involving
Local anesthetic toxicity: acute and chronic management Local anesthetics are commonly used medicines in clinical settings. They are used for pain management during minor interventional treatments, and for postoperative care after major surgeries. Cocaine is the well-known origin of local anesthetics, and the drug and related derivatives have long history of clinical usage for more than several centuries. Although illegal use of cocaine and its abuse are social problem in some countries, other (...) local anesthetics are safely and effectively used in clinics and hospitals all over the world. However, still this drug category has several side-effects and possibilities of rare but serious complications. Acute neurotoxicity and cardiac toxicity are derived from unexpected high serum concentration. Allergic reactions are observed in some cases, especially following the use of ester structure drugs. Chronic toxicity is provoked when nerve fibers are exposed to local anesthetics at a high
The Influence of Oral Ginger before Operation on Nausea and Vomiting after Cataract Surgery under General Anesthesia: A double-blind placebo-controlled randomized clinical trial. According to Iranian traditional medicine, using safe ginger may contribute to taking less chemical medicines and result in fewer side effects.To determine the influence of using ginger before operation on nausea and vomiting, after cataract surgery under general anesthesia.This study was a double-blind placebo
Position in the second stage of labour for women with epidural anaesthesia. Epidural analgesia for pain relief in labour prolongs the second stage of labour and results in more instrumental deliveries. It has been suggested that a more upright position of the mother during all or part of the second stage may counteract these adverse effects. This is an update of a Cochrane review first published in 2013.To assess the effects of different birthing positions (upright and recumbent) during
Topical anaesthesia for needle-related pain in newborn infants. Hospitalised newborn neonates frequently undergo painful invasive procedures that involve penetration of the skin and other tissues by a needle. One intervention that can be used prior to a needle insertion procedure is application of a topical local anaesthetic.To evaluate the efficacy and safety of topical anaesthetics such as amethocaine and EMLA in newborn term or preterm infants requiring an invasive procedure involving (...) anaesthetics amethocaine and eutectic mixture of local anaesthetics (EMLA) in terms of anaesthetic efficacy and safety in newborn term or preterm infants requiring an invasive procedure involving puncture of skin and other tissues with a needle DATA COLLECTION AND ANALYSIS: From the reports of the clinical trials we extracted data regarding clinical outcomes including pain, number of infants with methaemoglobin level 5% and above, number of needle prick attempts prior to successful needle-related procedure
Comparison of Regional vs. General Anesthesia for Surgical Repair of Open-Globe Injuries at a University Referral Center This study compares the clinical features and physician selection of either Regional Anesthesia (peribulbar or retrobulbar block) with Monitored Anesthesia Care (RA-MAC) or General Anesthesia (GA) for open globe injury repair.A non-randomized, comparative, retrospective case series at a University Referral Center.All adult repairable open globe injuries receiving primary (...) repair between January 1st, 2004 and December 31st, 2014 (11 years). Exclusion criteria were patients less than 18 years of age and those treated with primary enucleation.Data was gathered via retrospective chart review.Data collected from each patient was age, gender, injury type, location, length of wound, presenting visual acuity, classification of anesthesia used, duration of the procedure performed, months of clinical follow-up, and final visual acuity.During the 11 years study period, 448
Palliative radiation therapy for superior vena cava syndrome in metastatic Wilms tumor using 10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patientâ€”a teaching case 28740919 2018 11 13 2452-1094 2 1 2017 Jan-Mar Advances in radiation oncology Adv Radiat Oncol Palliative radiation therapy for superior vena cava syndrome in metastatic Wilms tumor using 10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patient-a teaching case. 101-104 10.1016/j.adro.2016.12.007
AND DEPOLARIZING MUSCLE RELAXANTS Background Potent volatile anesthetic agents are widely used and generally safe agents for inducing general anesthesia. The mechanism of action of these agents is unknown in spite of many hypotheses and inves- tigations. The agents include sevoflurane, halothane, enflurane, isoflurane, methoxyflurane, and desflurane; all of the currently available potent inhalation anesthetics are presumed to be equiva- lent triggers of malignant hyperthermia (MH). Depolarizing muscle (...) . If succinylcholine was administered, masseter muscle rigidity is often the first sign of MH. 5 If left untreated, an MH reaction can re- sult in cardiac arrest and death. 4 Any of the potent volatile anes- thetics, and the depolarizing muscle relaxant succinylcholine, can trigger an MH reaction in susceptible individuals. 5 Potent volatile anesthetics and succinylcholine are contraindicated in individu- als with MHS. MH episodes have an estimated incidence of be- tween 1/10,000 and 1/250,000 anesthesias
serve only as guidelines for the care of breastfeeding mothers and infants and do not delineate an exclusive course of treatment or serve as standards of medical care. Variations in treatment may be appropriate according to the needs of an individual patient. Background T hereislittlerigorousinformationinthescienti?c literature about anesthesia or procedural sedation in breastfeeding mothers. Recommendations in this area typi- cally focus on pharmacologic properties of anesthetic agents, limited (...) , single doses of meperidine/pethidine or diazepam are unlikely to affect the breastfeeding infant. 15 (III) Local anesthetics given by injection or topical application are considered safe for breastfeeding mothers. 2,3 (IV) Regional anesthesia. Regional anesthesia, including spinal, epidural, or peripheral nerve block, should be con- sidered whenever possible, whether for intraoperative anes- thesia or postoperative analgesia. 3 (IV) Regional anesthesia reduces the need for intraoperative medications
Pre-procedural fasting for inpatients undergoing interventional radiology or cardiac procedures not requiring general anesthesia Pre-procedural fasting for inpatients undergoing interventional radiology or cardiac procedures not requiring general anesthesia Pre-procedural fasting for inpatients undergoing interventional radiology or cardiac procedures not requiring general anesthesia Lavenberg JG, Holland S, Solano L, Stoudt G, Mitchell MD, Mull, N. Record Status This is a bibliographic record (...) of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Lavenberg JG, Holland S, Solano L, Stoudt G, Mitchell MD, Mull, N.. Pre-procedural fasting for inpatients undergoing interventional radiology or cardiac procedures not requiring general anesthesia. Philadelphia: Center for Evidence-based Practice (CEP). 2017 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Anesthesia
of booking, but the duty remains on the anaesthetist to ensure that the information is understood. 2 Immediately before induction of anaesthesia, for example in the anaesthetic room, is not an accept- able time to provide elective patients with new information other than in exceptional circum- stances. 3 The amount and the nature of information that should be provided to the patient should be deter- mined by the question: ‘What would this particu- lar patient regard as relevant when coming to a decision (...) ‘treatment’ is used in this document to indicate both treatment in the usual sense, that is, something used to ‘treat’ (alleviate) something, and also an anaesthetic intervention such as general/regional anaesthesia, etc). The importance of consent Ethical aspects Clinicians have an ethical obligation to respect patients’ autonomy – that is, their right to be involved in decisions that affect them. In medicine, this is re?ected in the requirement to obtain consent for treatment, which can only be valid
Effectiveness of Extracorporeal Shock Wave Therapy Without Local Anesthesia in Patients With Recalcitrant Plantar Fasciitis: A Meta-Analysis of Randomized Controlled Trials. The objective of this meta-analysis was to investigate the efficacy of extracorporeal shock wave therapy in the treatment of recalcitrant plantar fasciitis without local anesthesia.The Cochrane Library, EMBASE, PubMed, and Web of Science databases were searched from inception to September 2015 for randomized controlled (...) trials comparing ESWT without local anesthesia versus placebo for treatment of plantar fasciitis in adults. The primary outcome was the 12-week post-intervention success rate of reducing the visual analog scale score by 60% from baseline at the first step in the morning, reducing the VAS score by 60% from baseline during daily activities, reducing the Roles and Maudsley score, reducing overall heel pain, and reducing pain after applying a force meter.Nine studies were included in the meta-analysis
The effect of hydroalcoholic extract of Achillea eriophora DC. on blood pressure of anaesthetized male rat Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats. The acute effects of intravenous (i.v.) administration of different doses of HEAE (40, 50, 60, 80 mg/kg), and its probable interaction
Effectiveness of intrathecal dexmedetomidine as an adjuvant to bupivacaine spinal anesthesia in adult patients undergoing elective surgery: a systematic review protocol. The current review aims to identify the effects of intrathecal dexmedetomidine as an adjuvant to bupivacaine spinal anesthesia compared to the sole use of bupivacaine spinal anesthesia alone in adult patients undergoing elective surgical procedures.
and/or a surgeon requests for a regional anesthetic that would require needle trespass through tattooed skin. An additional qualitative objective is to identify the thoughts, opinions and biases related to the administration of a regional anesthetic through tattooed skin from the perspective of the patient, anesthesia provider, surgeon or other affected parties (e.g. patient families, hospital or clinic administrators or insurance providers). (...) Tattoos and administration of regional anesthesia: a comprehensive systematic review protocol. The review question is what is the impact of tattoos on the administration of regional anesthesia?The quantitative objective is to identify and quantify the risks to a patient when advancing a needle through tattooed skin for the purpose of administering a regional anesthetic.The qualitative objective is to investigate anesthesia providers' perceptions and experiences when presented with a patient
and local preemptive; B, spinal and local preemptive; C, general and placebo; D, spinal and placebo. After general or spinal anesthesia, each patient randomly received an injection of 7 mL of a mixture of local anesthetics or the same amount of normal saline. After 2, 4, 8, 12, 16, 24, 48, and 72 hours following the release of the tourniquet, the pain intensity level was measured with a visual analog scale (VAS). The use of additional analgesics and any adverse effects were also noted.Preemptive local (...) anesthesia (groups A and B) resulted in a significantly lower level of pain intensity during the first 24 hours after surgery. Until 8 hours after the release of the tourniquet, the pain intensity level was statistically lower in the groups A, B, and D in comparison to C. During hospitalization, none of the patients from groups A and B received on-demand ketoprofen intravenously. No side effects of local anesthetic agents were observed. Two patients had transient numbness and paresthesia in the field
Efficacy of Local Anesthetic With Dexamethasone on the Quality of Recovery Following Total Extraperitoneal Bilateral Inguinal Hernia Repair: A Randomized Clinical Trial Quality of recovery (directly associated with patient satisfaction) is an important clinical outcome measurement and a surrogate of anesthetic/surgical care quality.To compare the efficacy of a transversus abdominis plane (TAP) block with dexamethasone sodium phosphate and preperitoneal instillation of local anesthetic (PILA (...) ) with dexamethasone vs control on postoperative quality of recovery following a bilateral total extraperitoneal inguinal hernia repair (TEP-IHR) (>24 hours). Secondary objectives included efficacy of this technique on postoperative opioid use, nausea and vomiting, and pain scores.Conducted from November 2013 to August 2015, this randomized, prospective, single-blinded study compared 2 groups (a TAP block and PILA) with a standard anesthetic technique with no regional technique (control) following bilateral TEP
Opioid use after propofol or sevoflurane anesthesia: a randomized trial The intravenous anesthetic propofol is a gamma-aminobutyric acid A receptor agonist. Propofol promotes analgesia by depressing nociceptive transmission in peripheral neurons, antagonizing N-methyl-D-aspartate receptors, and activating gamma-aminobutyric acid A receptors in dorsal root ganglion receptor cells. Nevertheless, it remains unclear whether intraoperative propofol causes clinically meaningful postoperative (...) analgesia. We therefore tested the hypothesis that patients anesthetized with sevoflurane require a greater quantity of postoperative opioids (from the end of surgery until the next postoperative morning) than those anesthetized with propofol.With Institutional Review Board and EudraCT Number approval (2009-011038-82) and patients' informed consent, ninety patients scheduled for open vein stripping were randomized to either sevoflurane or propofol anesthesia at the Medical University of Vienna General
Moderate hypothermia and its effects in reducing the applied dose of anesthetics for patients with opium dependence in cardiac surgery: A randomized controlled trial. An increasing number of patients addicted to opium are experiencing awareness during coronary artery bypass surgery (CABG) as a result of tolerance to anesthetics.This research was primarily intended to determine the potential diminishing effects of moderate hypothermia on anesthetic dosage and recall of anesthesia during (...) and tear-shedding. To enhance the accuracy of our evaluation of anesthetic depth, we also used two questionnaires to test candidates' recall filled with the assistance of a colleague 24 hours following surgery. Independent-samples t-test and chi-square test were used by SPSS v 18 for data analysis.Eighty patients were studied in two groups of normothermic (N) (n = 40) and hypothermic (H) (n = 40). Given similar demographic data as well as the duration of surgery, we arrived at a propofol dose of 122.52