Latest & greatest articles for anaesthesia

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on anaesthesia or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on anaesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Anaesthesia

Clinical Anaesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of Anaesthesia:

  • Local and Regional
  • General
  • Sedation

Anaesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of Anaesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of Anaesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of Anaesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in Anaesthesia and the advancements in Anaesthesia practise by searching Trip.

Top results for anaesthesia

101. Guidelines on Checking Anaesthesia Delivery Systems

Guidelines on Checking Anaesthesia Delivery Systems PS31 2014 Page 1 PS31 2014 Australian and New Zealand College of Anaesthetists (ANZCA) Guidelines on Checking Anaesthesia Delivery Systems 1. INTRODUCTION An anaesthesia delivery system includes any equipment that can deliver gases, vapours, local anaesthetic or intravenous anaesthetic agents to induce and/or maintain anaesthesia. Failure of the anaesthesia delivery system can cause serious complications. This document is intended to assist (...) practitioners and health facilities to minimise equipment-related risks. This document applies wherever general anaesthesia, regional anaesthesia, local anaesthesia and/or sedation are administered by an anaesthetist. Henceforth, these activities are referred to as “anaesthesia”. 2. PRINCIPLES The following principles apply to the checking of anaesthesia delivery systems. 2.1 Responsibilities Each facility is required to designate an individual to be responsible for: 2.1.1 Servicing and maintaining

2014 Australian and New Zealand College of Anaesthetists

102. Statement on Staffing of Accredited Departments of Anaesthesia

Statement on Staffing of Accredited Departments of Anaesthesia PS42 2017 Page 1 PS42 2017 Australian and New Zealand College of Anaesthetists (ANZCA) Statement on Staffing of Accredited Departments of Anaesthesia 1. INTRODUCTION 1.1 Purpose and scope The Australian and New Zealand College of Anaesthetists (ANZCA) recognises the important role of anaesthesia departments providing training within the ANZCA training program. This document is intended to apply to anaesthesia departments accredited (...) staff have adequate allocated time for professional development. Anaesthetists who contribute more heavily to teaching, training, research and administration will require more sessions for clinical support activities. 2.1.1 Director of anaesthesia The director has a primary managerial responsibility to ensure that the department functions safely and efficiently. The director of anaesthesia must be a registered medical practitioner who holds the fellowship of ANZCA, or suitable anaesthesia

2014 Australian and New Zealand College of Anaesthetists

103. End-tidal Control software for use with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia

End-tidal Control software for use with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia End-tidal Control software for use with End-tidal Control software for use with Aisys Aisys closed circuit anaesthesia systems for closed circuit anaesthesia systems for automated gas control during gener automated gas control during general al anaesthesia anaesthesia Medtech innovation briefing Published: 16 September 2014 nice.org.uk/guidance/mib10 pathways © (...) NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 40Summary Summary Effectiv Effectiveness eness End-tidal Control is a gas delivery software option for the GE Healthcare Aisys Carestation and Aisys CS2 anaesthesia delivery systems. Five studies compared End-tidal Control with manual gas control: 1 randomised trial (n=200), 2 observational studies (n=3675, n=80), 1 service evaluation (n=489) and 1 audit

2014 National Institute for Health and Clinical Excellence - Advice

104. Guidelines on Checking Anaesthesia Delivery Systems

Guidelines on Checking Anaesthesia Delivery Systems PS31 2014 Page 1 PS31 2014 Australian and New Zealand College of Anaesthetists (ANZCA) Guidelines on Checking Anaesthesia Delivery Systems 1. INTRODUCTION An anaesthesia delivery system includes any equipment that can deliver gases, vapours, local anaesthetic or intravenous anaesthetic agents to induce and/or maintain anaesthesia. Failure of the anaesthesia delivery system can cause serious complications. This document is intended to assist (...) practitioners and health facilities to minimise equipment-related risks. This document applies wherever general anaesthesia, regional anaesthesia, local anaesthesia and/or sedation are administered by an anaesthetist. Henceforth, these activities are referred to as “anaesthesia”. 2. PRINCIPLES The following principles apply to the checking of anaesthesia delivery systems. 2.1 Responsibilities Each facility is required to designate an individual to be responsible for: 2.1.1 Servicing and maintaining

2014 Australian and New Zealand College of Anaesthetists

105. Guidance on the provision of anaesthesia services for post-operative care 2014

Guidance on the provision of anaesthesia services for post-operative care 2014 Document Store | The Royal College of Anaesthetists User menu Search Document Store This page displays listings of ALL publications added to the site. You can narrow down the list by entering keywords in the 'Search' field, and selecting 'Apply'. To filter the publications by section, tick the check-boxes of the desired sections, and select 'Apply'. You can set the ordering of the results by the publication title

2014 Royal College of Anaesthetists

106. Guidance on the provision of anaesthesia services for intra-operative care 2014

Guidance on the provision of anaesthesia services for intra-operative care 2014 Document Store | The Royal College of Anaesthetists User menu Search Document Store This page displays listings of ALL publications added to the site. You can narrow down the list by entering keywords in the 'Search' field, and selecting 'Apply'. To filter the publications by section, tick the check-boxes of the desired sections, and select 'Apply'. You can set the ordering of the results by the publication title

2014 Royal College of Anaesthetists

107. Guidance on the provision of anaesthesia services for emergency surgery 2014

Guidance on the provision of anaesthesia services for emergency surgery 2014 Document Store | The Royal College of Anaesthetists User menu Search Document Store This page displays listings of ALL publications added to the site. You can narrow down the list by entering keywords in the 'Search' field, and selecting 'Apply'. To filter the publications by section, tick the check-boxes of the desired sections, and select 'Apply'. You can set the ordering of the results by the publication title

2014 Royal College of Anaesthetists

108. Guidance on the provision of anaesthesia services for chronic pain management

Guidance on the provision of anaesthesia services for chronic pain management Document Store | The Royal College of Anaesthetists User menu Search Document Store This page displays listings of ALL publications added to the site. You can narrow down the list by entering keywords in the 'Search' field, and selecting 'Apply'. To filter the publications by section, tick the check-boxes of the desired sections, and select 'Apply'. You can set the ordering of the results by the publication title

2014 Royal College of Anaesthetists

109. Guidance on the provision of anaesthesia services for pre-operative assessment and preparation 2014

Guidance on the provision of anaesthesia services for pre-operative assessment and preparation 2014 Document Store | The Royal College of Anaesthetists User menu Search Document Store This page displays listings of ALL publications added to the site. You can narrow down the list by entering keywords in the 'Search' field, and selecting 'Apply'. To filter the publications by section, tick the check-boxes of the desired sections, and select 'Apply'. You can set the ordering of the results

2014 Royal College of Anaesthetists

110. Cataract surgery performed under local anaesthesia: guidelines

Cataract surgery performed under local anaesthesia: guidelines Cataract surgery performed under local anaesthesia: guidelines Cataract surgery performed under local anaesthesia: guidelines CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Cataract surgery performed under local anaesthesia: guidelines. Ottawa: Canadian Agency (...) for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions Three evidence-based guidelines were identified regarding cataract surgery performed under local anaesthesia. Final publication URL PubMedID Indexing Status Subject indexing assigned by NLM MeSH Anesthesia, Local; Cataract Extraction; Cough /prevention & controls Language Published English Country of organisation Canada Province or state Ontario English summary An English language summary is available. Address

2014 Health Technology Assessment (HTA) Database.

111. The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. (PubMed)

The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. Nitrous oxide is commonly used in general anaesthesia but concerns exist that it might increase perioperative cardiovascular risk. We aimed to gather evidence to establish whether nitrous oxide affects perioperative cardiovascular risk.We did an international, randomised, assessor-blinded trial in patients aged at least 45 years (...) 30 days of surgery. Our modified intention-to-treat population included all patients randomly assigned to groups and undergoing induction of general anaesthesia for surgery. This trial is registered at ClinicalTrials.gov, number NCT00430989.Of 10,102 eligible patients, we enrolled 7112 patients between May 30, 2008, and Sept 28, 2013. 3543 were assigned to receive nitrous oxide and 3569 were assigned not to receive nitrous oxide. 3483 patients receiving nitrous oxide and 3509 not receiving

2014 Lancet

112. Regional Anaesthesia and Patients with Abnormalities of Coagulation

Regional Anaesthesia and Patients with Abnormalities of Coagulation November 2013 Regional Anaesthesia and Patients with Abnormalities of Coagulation Published by The Association of Anaesthetists of Great Britain & Ireland The Obstetric Anaesthetists’ Association Regional Anaesthesia UK This guideline was originally published in Anaesthesia. If you wish to refer to this guideline, please use the following reference: Association of Anaesthetists of Great Britain and Ireland, Obstetric (...) Anaesthetists’ Association and Regional Anaesthesia UK. Regional anaesthesia and patients with abnormalities of coagulation. Anaesthesia 2013; 68: pages 966-72. This can be viewed online via the following URL: http://onlinelibrary.wiley.com/doi/10.1111/anae.12359/abstract Guidelines Regional anaesthesia and patients with abnormalities of coagulation The Association of Anaesthetists of Great Britain & Ireland The Obstetric Anaesthetists Association Regional Anaesthesia UK Membership of the Working Party: W

2014 Association of Anaesthetists of GB and Ireland

113. High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. (PubMed)

High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. The role of positive end-expiratory pressure in mechanical ventilation during general anaesthesia for surgery remains uncertain. Levels of pressure higher than 0 cm H2O might protect against postoperative pulmonary complications but could also cause intraoperative circulatory depression and lung injury from overdistension. We tested (...) the hypothesis that a high level of positive end-expiratory pressure with recruitment manoeuvres protects against postoperative pulmonary complications in patients at risk of complications who are receiving mechanical ventilation with low tidal volumes during general anaesthesia for open abdominal surgery.In this randomised controlled trial at 30 centres in Europe and North and South America, we recruited 900 patients at risk for postoperative pulmonary complications who were planned for open abdominal

Full Text available with Trip Pro

2014 Lancet

114. Ultrasound imaging in the practice of anaesthesia

Ultrasound imaging in the practice of anaesthesia 1 Public Summary Document Application 1183 – Ultrasound Imaging in the practice of anaesthesia Applicant: Australian Society of Anaesthetists Date of MSAC consideration: MSAC 62 nd Meeting, 26-28 November 2014 Context for decision: MSAC makes its advice in accordance with its Terms of Reference, see at www.msac.gov.au 1. Purpose of application and links to other applications An application requesting MBS listing of ultrasound imaging (...) for the practice of anaesthesia for patients requiring a central line catheter for vascular access or percutaneous neural blockade was received from Australian Society of Anaesthetists (ASA) by the Department of Health and Ageing in January 2012. The application was further updated in May 2012. 2. MSAC’s advice to the Minister After considering the available evidence in relation to safety, clinical effectiveness and cost- effectiveness, MSAC does not support public funding because of uncertain cost

2014 Medical Services Advisory Committee

115. Local versus general anaesthesia for carotid endarterectomy. (PubMed)

Local versus general anaesthesia for carotid endarterectomy. Carotid endarterectomy may significantly reduce the risk of stroke in people with recently symptomatic, severe carotid artery stenosis. However, there are significant perioperative risks that may be reduced by performing the operation under local rather than general anaesthetic. This is an update of a Cochrane Review first published in 1996, and previously updated in 2004 and 2008.To determine whether carotid endarterectomy under (...) the local anaesthesia group and the general anaesthesia group. The incidence of strokes in the local anaesthesia group was 3.2% compared to 3.5% in the general anaesthesia group (Peto OR 0.92, 95% CI 0.67 to 1.28). There was no statistically significant difference in the proportion of patients who had a stroke or died within 30 days of surgery. In the local anaesthesia group 3.6% of patients had a stroke or died compared to 4.2% of patients in the general anaesthesia group (Peto OR 0.85, 95% CI 0.63

Full Text available with Trip Pro

2013 Cochrane

116. Infraclavicular brachial plexus block for regional anaesthesia of the lower arm. (PubMed)

Infraclavicular brachial plexus block for regional anaesthesia of the lower arm. Several approaches exist to produce local anaesthetic blockade of the brachial plexus. It is not clear which is the technique of choice for providing surgical anaesthesia of the lower arm, although infraclavicular blockade (ICB) has several purported advantages. We therefore performed a systematic review of ICB compared to the other brachial plexus blocks (BPBs). This review was originally published in 2010 (...) and was updated in 2013.The objective of this review was to evaluate the efficacy and safety of infraclavicular block (ICB) compared to other approaches to the brachial plexus in providing regional anaesthesia for surgery on the lower arm.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2013, Issue 5); MEDLINE (1966 to June 2013) via OvidSP; and EMBASE (1980 to June 2013) via OvidSP. We also searched conference proceedings (from 2004 to 2012

Full Text available with Trip Pro

2013 Cochrane

117. Neuraxial anaesthesia for lower-limb revascularization. (PubMed)

Neuraxial anaesthesia for lower-limb revascularization. Lower-limb revascularization is a surgical procedure that is performed to restore an adequate blood supply to the limbs. Lower-limb revascularization surgery is used to reduce pain and sometimes to improve lower-limb function. Neuraxial anaesthesia is an anaesthetic technique that uses local anaesthetics next to the spinal cord to block nerve function. Neuraxial anaesthesia may lead to improved survival. This systematic review (...) was originally published in 2010 and was first updated in 2011 and again in 2013.To determine the rates of death and major complications associated with spinal and epidural anaesthesia as compared with other types of anaesthesia for lower-limb revascularization in patients aged 18 years or older who are affected by obstruction of lower-limb vessels.The original review was published in 2010 and was based on a search until June 2008. In 2011 we reran the search until February 2011 and updated the review

2013 Cochrane

118. Intravenous versus inhalation anaesthesia for one-lung ventilation. (PubMed)

Intravenous versus inhalation anaesthesia for one-lung ventilation. This is an update of a Cochrane Review first published in The Cochrane Library, Issue 2, 2008.The technique called one-lung ventilation can confine bleeding or infection to one lung, prevent rupture of a lung cyst or, more commonly, facilitate surgical exposure of the unventilated lung. During one-lung ventilation, anaesthesia is maintained either by delivering an inhalation anaesthetic to the ventilated lung or by infusing (...) an intravenous anaesthetic. It is possible that the method chosen to maintain anaesthesia may affect patient outcomes. Inhalation anaesthetics may impair hypoxic pulmonary vasoconstriction (HPV) and increase intrapulmonary shunt and hypoxaemia.The objective of this review was to evaluate the effectiveness and safety of intravenous versus inhalation anaesthesia for one-lung ventilation.We searched the Cochrane Central Register of Controlled Trials (CENTRAL); The Cochrane Library (2012, Issue 11); MEDLINE

Full Text available with Trip Pro

2013 Cochrane

119. Supplemental oxygen for caesarean section during regional anaesthesia. (PubMed)

Supplemental oxygen for caesarean section during regional anaesthesia. Supplementary oxygen is routinely administered to low-risk pregnant women during an elective caesarean section under regional anaesthesia; however, maternal and foetal outcomes have not been well established.The primary objective was to determine whether supplementary oxygen given to low-risk term pregnant women undergoing elective caesarean section under regional anaesthesia can prevent maternal and neonatal desaturation (...) under regional anaesthesia and compared outcomes with, and without, oxygen supplementation.Two review authors independently extracted data, assessed methodological quality and performed subgroup and sensitivity analyses.We included 10 trials with a total of 683 participants. Supplementary oxygen administration varied widely in dose and duration between trials. No cases of maternal desaturation were reported, although none of the 10 trials focused on maternal desaturation. Significant differences

2013 Cochrane

120. Immediate Post-anaesthesia recovery

Immediate Post-anaesthesia recovery UK National Core Competencies for Post-anaesthesia Care 2013 Immediate Post-anaesthesia Recovery 2013 supplement2 CONTENTS Glossary of terms 3 Introduction 5 Competency 1 Communication 7 Competency 2 Professional development 9 Competency 3 Clinical leadership 10 Competency 4 Clinical governance 11 Competency 5 Assessment and management of the airway 13 Competency 6 Assessment and management of breathing 16 Competency 7 Assessment and management (...) hyperpyrexia NCEPOD National Confidential Enquiry into Patient Outcome and Death NES NHS Education Scotland NIBP Non-invasive blood pressure NMC Nursing and Midwifery Council NPSA National Patient Safety Agency ODP Operating department practitioner PACU Post-anaesthesia care unit 4 PCA Patient controlled analgesia pCO2 Partial pressure of carbon dioxide PDP Personal development plan PONV Postoperative nausea and vomiting PPE Personal protective equipment QIS NHS Quality Improvement Scotland RAE Ring/Adair

2013 Association of Anaesthetists of GB and Ireland