Latest & greatest articles for anaesthesia

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This page lists the very latest high quality evidence on anaesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anaesthesia

Clinical Anaesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of Anaesthesia:

  • Local and Regional
  • General
  • Sedation

Anaesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of Anaesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of Anaesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of Anaesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in Anaesthesia and the advancements in Anaesthesia practise by searching Trip.

Top results for anaesthesia

61. Use of Anesthesia Providers in the Administration of Office-based Deep Sedation/General Anesthesia to the Pediatric Dental Patient

of pediatric emergencies is critical in providing safe sedation and anesthetic care. During deep sedation/general anesthesia in the dental setting, there must be at least two individuals pre- sent with the skills in patient rescue and pediatric advanced life support (e.g., PALS) and capable of managing any emergency event. 4 One of the two must be an independent observer who sole responsibility is to constantly observe the patient’s vital signs, levels of sedation, airway patency, and adequacy (...) ., the responsible dental practitioner) must be trained in and capable of providing pediatric advanced life support and skilled in assisting the independent observer with the rescue of a child with any of the adverse events described above. Personnel experienced in post anesthetic recovery care and trained in advanced resuscitative techniques (e.g., PALS) must be in attendance and provide continuous respiratory and car- diovascular monitoring during the recovery period. 4 The supervising anesthesia provider

2018 American Academy of Pediatric Dentistry

62. Readiness for Discharge After Foot and Ankle Surgery Using Peripheral Nerve Blocks: A Randomized Controlled Trial Comparing Spinal and General Anesthesia as Supplements to Nerve Blocks (Abstract)

Readiness for Discharge After Foot and Ankle Surgery Using Peripheral Nerve Blocks: A Randomized Controlled Trial Comparing Spinal and General Anesthesia as Supplements to Nerve Blocks Neuraxial anesthesia is often viewed as superior to general anesthesia but may delay discharge. Comparisons do not typically use multimodal analgesics and nerve blockade. Combining nerve blockade with general anesthesia may reduce pain, opioid consumption, and nausea. We hypothesized that general anesthesia (...) (with nerve blocks) would lead to earlier readiness for discharge, compared to spinal anesthesia (with nerve blocks).All patients underwent ambulatory foot and ankle surgery, with a predicted case duration of 1-3 hours. All patients received popliteal and adductor canal nerve blocks using bupivacaine and dexamethasone. No intraoperative opioids were administered. All patients received ondansetron, dexamethasone, ketamine, and ketorolac. Patients, data collectors, and the data analyst were not informed

2018 EvidenceUpdates

63. [Ethyl chloride aerosol spray for local anesthesia before arterial puncture: randomized placebo-controlled trial]. (Abstract)

[Ethyl chloride aerosol spray for local anesthesia before arterial puncture: randomized placebo-controlled trial]. To compare the efficacy of an ethyl chloride aerosol spray to a placebo spray applied in the emergency department to the skin to reduce pain from arterial puncture for blood gas analysis.Single-blind, randomized placebo-controlled trial in an emergency department of Hospital de Basurto in Bilbao, Spain. We included 126 patients for whom arterial blood gas analysis had been ordered

2018 Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias Controlled trial quality: predicted high

64. Injectable local anaesthetic agents for dental anaesthesia. Full Text available with Trip Pro

Injectable local anaesthetic agents for dental anaesthesia. Pain during dental treatment, which is a common fear of patients, can be controlled successfully by local anaesthetic. Several different local anaesthetic formulations and techniques are available to dentists.Our primary objectives were to compare the success of anaesthesia, the speed of onset and duration of anaesthesia, and systemic and local adverse effects amongst different local anaesthetic formulations for dental anaesthesia. We (...) generation, allocation concealment, masking of local anaesthetic cartridges for administrators or outcome assessors, or participant dropout or exclusion.We reported results for the eight most important comparisons.Success of anaesthesiaWhen the success of anaesthesia in posterior teeth with irreversible pulpitis requiring root canal treatment is tested, 4% articaine, 1:100,000 epinephrine, may be superior to 2% lidocaine, 1:100,000 epinephrine (31% with 2% lidocaine vs 49% with 4% articaine; risk ratio

2018 Cochrane

65. Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy

Reference Manager Save my selection Regional Anesthesia and Pain Medicine: doi: 10.1097/AAP.0000000000000763 REGIONAL ANESTHESIA AND ACUTE PAIN: SPECIAL ARTICLE Free From the *Mayo Clinic, Rochester, MN; †Katholieke Universiteit, Leuven, Belgium; ‡Bielefeld Hospital, Bielefeld, Germany; §Massachusetts General Hospital, Boston, MA; and ∥Northwestern University, Chicago, IL. Accepted for publication January 21, 2018. Address correspondence to: Terese T. Horlocker, MD, Department of Anesthesiology (...) Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy Regional Anesthesia in the Patient Receiving Antithrombotic... : Regional Anesthesia and Pain Medicine You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Login No user account? Lippincott Journals Subscribers , use your username or email along with your password to log in. Remember me on this computer Register for a free account Registered

2018 American Society of Regional Anesthesia and Pain Medicine

66. Benefit and Harm of Adding Epinephrine to a Local Anesthetic for Neuraxial and Locoregional Anesthesia: A Meta-analysis of Randomized Controlled Trials With Trial Sequential Analyses Full Text available with Trip Pro

Benefit and Harm of Adding Epinephrine to a Local Anesthetic for Neuraxial and Locoregional Anesthesia: A Meta-analysis of Randomized Controlled Trials With Trial Sequential Analyses This systematic review examines the benefit and harm of adding epinephrine to local anesthetics for epidural, intrathecal, or locoregional anesthesia.We searched electronic databases to October 2017 for randomized trials comparing any local anesthetic regimen combined with epinephrine, with the same local (...) (1%) for multiple outcome testing.We identified 70 trials (3644 patients, 17 countries, from 1970 to 2017). Median number of patients per trial was 44 (range, 9-174). Thirty-seven trials (1781 patients) tested epinephrine for epidural, 27 (1660) for intrathecal, and 6 (203) for locoregional anesthesia (sciatic, femoral, popliteal, axillary blocks). TSA enabled us to conclude that adding epinephrine to epidural local anesthetics could not decrease postoperative pain intensity by 30%, and did

2018 EvidenceUpdates

67. Clonidine versus other adjuncts added to local anesthetics for pediatric neuraxial blocks: a systematic review and meta-analysis Full Text available with Trip Pro

Clonidine versus other adjuncts added to local anesthetics for pediatric neuraxial blocks: a systematic review and meta-analysis Clonidine is a common adjunct to local anesthetics for pediatric neuraxial block; however, the pros and cons between clonidine and other adjuncts remain unclear. Thus, we performed this meta-analysis of randomized controlled trials to assess the efficacy and adverse effects between clonidine and other adjuncts added to local anesthetics.The systematic search, data (...) with other adjuncts, added to local anesthetics for neuraxial block, provides a longer duration of postoperative analgesia with lower incidence of PONV. However, the duration of motor block may also be prolonged by clonidine.

2018 EvidenceUpdates

68. Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. Full Text available with Trip Pro

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. Regional anaesthesia may reduce the rate of persistent postoperative pain (PPP), a frequent and debilitating condition. This review was originally published in 2012 and updated in 2017.To compare local anaesthetics and regional anaesthesia versus conventional analgesia for the prevention of PPP beyond three months in adults and children undergoing (...) three to 12 months after breast cancer surgery with an OR of 0.43 (95% CI 0.28 to 0.68, 1297 participants, low-quality evidence). Pooling data at three to 8 months after surgery from four RCTs favoured regional anaesthesia after caesarean section with an OR of 0.46, (95% CI 0.28 to 0.78; 551 participants, moderate-quality evidence). Evidence synthesis of three RCTs investigating continuous infusion with local anaesthetic for the prevention of PPP three to 55 months after iliac crest bone graft

2018 Cochrane

69. Recent Trends in the Practice of Procedural Sedation Under Local Anesthesia for Catheter Ablation, Gastrointestinal Endoscopy, and Endoscopic Surgery in Japan: A Retrospective Database Study in Clinical Practice from 2012 to 2015 Full Text available with Trip Pro

Recent Trends in the Practice of Procedural Sedation Under Local Anesthesia for Catheter Ablation, Gastrointestinal Endoscopy, and Endoscopic Surgery in Japan: A Retrospective Database Study in Clinical Practice from 2012 to 2015 To investigate changes in sedation practice during 2012-2015, using a large health claims database, for catheter ablation (CA), gastrointestinal endoscopic examination (EE), and surgery (ES) after dexmedetomidine (DEX) was approved for procedural sedation in 2013. We (...) assessed the trends of sedative utilization, sedative-analgesic combinations, and, additionally, incidence of complications from 2012 to 2015.Using the database provided by Medical Data Vision Co., Ltd. (Tokyo, Japan), annual utilization proportions of the sedatives and sedative-analgesic combinations and occurrence of complications were calculated in patients with a record of local anesthesia and CA, EE, and/or ES but without general anesthesia used on the same day. The sedatives studied were DEX

2018 Drugs - real world outcomes

70. The Efficacy of Vibration Anesthesia on Reducing Pain Levels During Lip Augmentation: Worth the Buzz? Full Text available with Trip Pro

The Efficacy of Vibration Anesthesia on Reducing Pain Levels During Lip Augmentation: Worth the Buzz? Lip augmentation procedures have increased drastically in the last years as patients seek to enhance the shape and size of their lips with dermal fillers. One of the main concerns faced with these procedures is the pain inflicted through injections. On the other hand, many different techniques have been introduced for the reduction of pain while performing office-based minimal invasive (...) procedures.This study aims to determine the analgesic effect of vibration anesthesia during lip augmentation procedures and to evaluate its overall effect on the comfort of patients.A split-lip study was designed in a randomized fashion for 25 lip augmentation patients who received hyaluronic acid fillers with or without with a concurrent vibration stimulus on either half of their lips. Patients were asked to score the pain that they felt during lip injections on a scale from 0 to 10 (0 being no pain and 10

2018 Aesthetic surgery journal Controlled trial quality: uncertain

71. Pain control in surgical abortion part 1 ? local anesthesia and minimal sedation

. Islocalanesthesiaeffectiveforpaincontrolinsurgicalabortion? Women receiving local cervical anesthesia alone for ?rst- trimestersurgicalabortionreport,onaverage,experiencing moderatepainrangingfrom4to7outof10[19,42–46]com- paredto8to9outof10withshamlocalcervicalanesthesia [21]. The PCB anesthetizes the nervebundles lateral to the cervixat3o'clockand9o'clockaswellasthosewithinthe uterosacral ligaments. In a randomized controlled trial of 120 women undergoing surgical abortion at less than 11 weeks [21], a PCB with 20 mL of 1% buffered lidocaine (...) Pain control in surgical abortion part 1 ? local anesthesia and minimal sedation Reviewarticle SocietyofFamilyPlanningclinicalguidelinespaincontrolinsurgical abortionpart1 —localanesthesiaandminimalsedation RebeccaH.Allen a, ?,RameetSingh b a ObstetricsandGynecology,WarrenAlpertMedicalSchoolofBrownUniversity,WomenandInfantsHospital,101DudleyStreet,Providence,RI02905 b DivisionofFamilyPlanning,DepartmentofObstetricsandGynecology,UniversityofNewMexicoSchoolofMedicine,Albuquerque,NM87131 abstract

2018 Society of Family Planning

72. Intravenous Local Anaesthetic Compared with Intraperitoneal Local Anaesthetic in Abdominal Surgery: A Systematic Review (Abstract)

Intravenous Local Anaesthetic Compared with Intraperitoneal Local Anaesthetic in Abdominal Surgery: A Systematic Review Modern perioperative care strategies aim to optimise perioperative care by reducing the body's stress response to surgery. A major facet of optimising an abdominal surgery analgesia programme is using a multimodal opioid sparing approach. Local anaesthetics have shown promise and there has been considerable research into the most effective route for their administration (...) . This review aims to determine if there is a difference in analgesic efficacy between intraperitoneal local anaesthetic (IPLA) and intravenous local anaesthetic (IVLA).In concordance with the PRISMA statement, a literature search was conducted to identify randomised control trials that compared IVLA with IPLA in abdominal surgery. The primary outcomes of interest were opioid analgesia requirements and pain score assessed by visual analogue score. Data were extracted and entered into pre-designed electronic

2018 EvidenceUpdates

73. Ketamine-based anesthesia improves electroconvulsive therapy outcomes: a randomized-controlled study Full Text available with Trip Pro

Ketamine-based anesthesia improves electroconvulsive therapy outcomes: a randomized-controlled study Major depressive disorder (MDD) is a common and debilitating condition that can be challenging to treat. Electroconvulsive therapy (ECT) is currently the therapeutic gold standard for treatment-resistant MDD. We tested our hypothesis that ketamine-based anesthesia for ECT results in superior improvement in treatment-resistant MDD outcomes compared with propofol-based anesthesia.Patients (...) with treatment-resistant MDD were enrolled in a randomized clinical trial with assignment to ketamine- or propofol-based anesthesia arms. Using a modified intention-to-treat analysis, we compared the median number of ECT treatments required to achieve a 50% reduction (primary outcome) and a score ≤ 10 (secondary outcome) on the Montgomery-Asberg depression rating scale (MADRS) between anesthesia groups.The study was terminated as significant results were found after the first planned interim analysis with 12

2018 EvidenceUpdates

74. Psoas Compartment Block vs Periarticular Local Anesthetic Infiltration for Pain Management After Anterior Total Hip Arthroplasty: A Prospective, Randomized Study (Abstract)

Psoas Compartment Block vs Periarticular Local Anesthetic Infiltration for Pain Management After Anterior Total Hip Arthroplasty: A Prospective, Randomized Study The psoas compartment block (PCB) or periarticular soft-tissue local anesthetic injection are forms of regional anesthesia often used as one of the components in multimodal anesthesia applied during total hip arthroplasty (THA). The most efficacious form of regional anesthesia for THA has yet to be determined.In a single-surgeon (...) , prospective, clinical trial, patients undergoing THA via direct anterior approach were randomized to receive an intraoperative periarticular local anesthetic infiltration (periarticular injection) or a PCB. Postoperative pain scores, narcotic consumption, and complications were recorded.Forty-nine patients were randomized to the PCB and 50 were randomized to the periarticular injection. The resting pain score 3 hours postoperatively was statistically significantly lower in the periarticular injection

2018 EvidenceUpdates

75. Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia. Full Text available with Trip Pro

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia. People with a low platelet count (thrombocytopenia) often require lumbar punctures or an epidural anaesthetic. Lumbar punctures can be diagnostic (haematological malignancies, subarachnoid haematoma, meningitis) or therapeutic (spinal anaesthetic, administration of chemotherapy). Epidural catheters are placed for administration of epidural (...) anaesthetic. Current practice in many countries is to correct thrombocytopenia with platelet transfusions prior to lumbar punctures and epidural anaesthesia, in order to mitigate the risk of serious procedure-related bleeding. However, the platelet count threshold recommended prior to these procedures varies significantly from country to country. This indicates significant uncertainty among clinicians regarding the correct management of these patients. The risk of bleeding appears to be low

2018 Cochrane

76. Effect of adding dexamethasone to lidocaine on the quality of intravenous regional anesthesia for upper extremity orthopedic operations: A randomized clinical trial Full Text available with Trip Pro

Effect of adding dexamethasone to lidocaine on the quality of intravenous regional anesthesia for upper extremity orthopedic operations: A randomized clinical trial Intravenous regional anesthesia (IVRA) is an ideal technique for short surgery on the distal extremities. Different additives have been used to improve lidocaine's block quality.The aim of this study was to determine the effect of adding dexamethasone to lidocaine on improving the quality of IVRA.This study is a prospective, double

2018 Electronic physician Controlled trial quality: uncertain

77. Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. Full Text available with Trip Pro

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. Regional anaesthesia may reduce the rate of persistent postoperative pain (PPP), a frequent and debilitating condition. This review was originally published in 2012 and updated in 2017.To compare local anaesthetics and regional anaesthesia versus conventional analgesia for the prevention of PPP beyond three months in adults and children undergoing (...) three to 12 months after breast cancer surgery with an OR of 0.43 (95% CI 0.28 to 0.68, 1297 participants, low-quality evidence). Pooling data at three to 8 months after surgery from four RCTs favoured regional anaesthesia after caesarean section with an OR of 0.46, (95% CI 0.28 to 0.78; 551 participants, moderate-quality evidence). Evidence synthesis of three RCTs investigating continuous infusion with local anaesthetic for the prevention of PPP three to 55 months after iliac crest bone graft

2018 Cochrane

78. Anaesthetizing children—From a nurse anaesthetist's perspective—A qualitative study Full Text available with Trip Pro

Anaesthetizing children—From a nurse anaesthetist's perspective—A qualitative study The aim of this study was to describe nurse anaesthetists' experiences of encountering and caring for children in connection to anaesthesia.Qualitative design.Sixteen written narratives based on eight nurse anaesthetists' experiences of meeting children was analysed using qualitative content analysis.The overarching theme was: "anaesthetizing children is a complex caring situation, including interactions (...) ' needs are essential for an optimal caring situation. Organizations need to realize that extra time, skills and resources are needed to safely anaesthetize children.

2018 Nursing open

79. Bilateral corneal denting after surgery under general anesthesia: A case report Full Text available with Trip Pro

Bilateral corneal denting after surgery under general anesthesia: A case report To report a case of temporary bilateral corneal denting in a patient who underwent cardiovascular surgery under general anesthesia.A 71-year-old male with no history of ophthalmological disease experienced bilateral corneal denting immediately after undergoing surgery for aneurysm of the thoracic aorta under general anesthesia. Anesthesia was induced with propofol and maintained with rocuronium bromide (...) and remifentanil hydrochloride. The initial examination revealed significant denting on the surface of both the corneas and ocular hypotension. Visual evaluation could not be performed due to the patient's low level of consciousness resulting from delayed emergence from anesthesia. After applying tropicamide and phenylephrine ophthalmic solution for fundus examination, the ocular morphology improved. Ocular pressure was normal on the day after surgery, and creasing on the surface of the corneas had

2018 American journal of ophthalmology case reports

80. Checklist for Treatment of Local Anesthetic Systemic Toxicity

Checklist for Treatment of Local Anesthetic Systemic Toxicity FIGURE1. ASRALASTChecklist. Regional Anesthesia and Pain Medicine • Volume43,Number2,February2018 ASRA Checklist for Managing LAST © 2018 AmericanSociety of Regional Anesthesia andPain Medicine 151FIGURE1. Continued Neal et al Regional Anesthesia and Pain Medicine • Volume43, Number2, February2018 152 © 2018 American Society ofRegionalAnesthesia and Pain Medicine

2018 American Society of Regional Anesthesia and Pain Medicine