Latest & greatest articles for anaesthesia

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This page lists the very latest high quality evidence on anaesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Anaesthesia

Clinical Anaesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of Anaesthesia:

  • Local and Regional
  • General
  • Sedation

Anaesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of Anaesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of Anaesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of Anaesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in Anaesthesia and the advancements in Anaesthesia practise by searching Trip.

Top results for anaesthesia

261. Cost-effectiveness of inhalational, balanced and total intravenous anaesthesia for ambulatory knee surgery

Cost-effectiveness of inhalational, balanced and total intravenous anaesthesia for ambulatory knee surgery Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

1997 NHS Economic Evaluation Database.

262. Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials

Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials Tramer M, Moore A, McQuay H Authors' objectives To carry out (...) this review are available on the Bandolier website (see Other Publications of Related Interest). Bibliographic details Tramer M, Moore A, McQuay H. Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials. British Journal of Anaesthesia 1996; 76(2): 186-193 PubMedID Original Paper URL Other publications of related interest Additional data relating to this study are available on the following website: (accessed July

1996 DARE.

263. Epidural anaesthesia and spinal haematoma

Epidural anaesthesia and spinal haematoma Epidural anaesthesia and spinal haematoma Epidural anaesthesia and spinal haematoma Wulf H Authors' objectives To present a comprehensive review of case reports about haematoma formation in the spinal canal due to epidural anaesthesia. Searching MEDLINE was searched for case reports published from 1966 to 1995 using the keywords 'epidural*', 'ana(e)sthesia', 'haematoma', 'epidural' and 'ana(e)sthesia complication'. Previous reviews and relevant (...) anaesthesia journals were examined for additional cases. Study selection Study designs of evaluations included in the review Case reports with definite haematomas were included. Specific interventions included in the review The intervention was epidural anaesthesia or attempted epidural anaesthesia. Participants included in the review Patients receiving epidural anaesthesia with definite spinal haematoma (confirmed at neurosurgical intervention or autopsy) were included. Outcomes assessed in the review

Full Text available with Trip Pro

1996 DARE.

264. Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia

Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia Curatolo M, Derighetti M, Petersen-Felix S, Feigenwinter P, Fischer M, Zbinden A M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Fuzzy logic control of inspired isoflurane and oxygen concentrations in minimal flow general anaesthesia. Type of intervention Anaesthesia. Economic study type Cost-effectiveness analysis. Study population Patients undergoing discectomy for lumbar or cervical disc herniation for which general

1996 NHS Economic Evaluation Database.

265. Cost analysis of propofol versus thiopental induction anaesthesia in outpatient laparoscopic gynaecologic surgery

Cost analysis of propofol versus thiopental induction anaesthesia in outpatient laparoscopic gynaecologic surgery Cost analysis of propofol versus thiopental induction anaesthesia in outpatient laparoscopic gynaecologic surgery Cost analysis of propofol versus thiopental induction anaesthesia in outpatient laparoscopic gynaecologic surgery Wagner B K, O'Hara D A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Use of Propofol and Thiopental anaesthesia in outpatient laparoscopic gynaecologic surgery. Type of intervention Anaesthetic. Economic study type Cost-effectiveness analysis. Study population Patients who underwent laparoscopic gynaecologic surgery. Setting Hospital. The economic study took place in New Jersey, USA

1995 NHS Economic Evaluation Database.

266. Prevention of atelectasis during general anaesthesia. (PubMed)

Prevention of atelectasis during general anaesthesia. Atelectasis is an important cause of impaired gas exchange during general anaesthesia; it causes pulmonary shunting. We studied the effects of gas composition on the formation of atelectasis and on gas exchange during the induction of general anaesthesia. In 12 adult patients, the lungs were ventilated with 30% oxygen in nitrogen during anaesthesia induction, and in another 12, a conventional technique was used (100% oxygen during induction (...) and 40% oxygen in nitrogen thereafter). Extent of atelectasis was estimated by computed tomography and the ventilation-perfusion relation (VA/Q) by the multiple inert gas elimination technique. After anaesthesia induction, there was little atelectasis in the 30% oxygen group (mean 0.2 [SD 0.4] cm2) and a significantly greater amount (4.2 [5-6] cm2; p < 0.001) in the 100% oxygen group. Patients in the 30% oxygen group were observed for another 40 min. 6 continued to receive 30% oxygen (subgroup

1995 Lancet Controlled trial quality: uncertain

267. Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia. Trial Group Mainz/Marburg. (PubMed)

Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia. Trial Group Mainz/Marburg. Although histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant cardiorespiratory disturbances serious enough to warrant prophylaxis with antihistamines. We have assessed the incidence and importance of histamine release in a randomised 2 x 2 factorial (...) study. 240 patients representing a routine throughput of major general surgery were studied during a standardised induction of anaesthesia and preoperative loading of the circulation with either Ringer solution or Haemaccel-35, with or without antihistamine prophylaxis with dimetindene (H1) plus cimetidine (H2). Cardiorespiratory disturbances were graded as detectable, clinically relevant, or life-threatening from observers' records of the anaesthesia and the actions taken by the anaesthetists

1994 Lancet Controlled trial quality: uncertain

268. Cognitive and functional competence after anaesthesia in patients aged over 60: controlled trial of general and regional anaesthesia for elective hip or knee replacement. (PubMed)

Cognitive and functional competence after anaesthesia in patients aged over 60: controlled trial of general and regional anaesthesia for elective hip or knee replacement. To determine the influence of general or regional anaesthesia on long term mental function in elderly patients.Prospective study of patients randomly allocated to receive general or regional anaesthesia.The patients' homes and a large teaching hospital in Cardiff.146 Patients aged 60 and over scheduled for elective hip or knee (...) replacement.Scores achieved in tests of cognitive function and functional competence.72 Patients were allocated to receive general anaesthesia and 74 regional anaesthesia. Anaesthetic technique did not influence the duration of the operation, time to mobilisation postoperatively, requirements for analgesia after the operation, or duration of stay in hospital. Three months after the operation there was an improvement in the score for the recognition component (76 ms, 95% confidence interval 9 to 144

Full Text available with Trip Pro

1990 BMJ Controlled trial quality: uncertain

269. Improved recovery and reduced postoperative stay after therapeutic suggestions during general anaesthesia. (PubMed)

Improved recovery and reduced postoperative stay after therapeutic suggestions during general anaesthesia. The clinical value of therapeutic suggestions during general anaesthesia was assessed in a double-blind randomised placebo-controlled study. 39 unselected patients were allocated to suggestion (n = 19) or control (n = 20) groups who were played either recorded therapeutic suggestions or a blank tape, respectively, during hysterectomy. The patients in the suggestion group spent

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1988 Lancet Controlled trial quality: uncertain

270. Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. (PubMed)

Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. In a randomised controlled trial, preterm babies undergoing ligation of a patent ductus arteriosus were given nitrous oxide and d-tubocurarine, with (n = 8) or without (n = 8) the addition of fentanyl (10 micrograms/kg intravenously) to the anaesthetic regimen. Major hormonal responses to surgery, as indicated by changes in plasma adrenaline, noradrenaline, glucagon, aldosterone (...) . The findings indicate that preterm babies mount a substantial stress response to surgery under anaesthesia with nitrous oxide and curare and that prevention of this response by fentanyl anaesthesia may be associated with an improved postoperative outcome.

1987 Lancet Controlled trial quality: uncertain

271. Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. (PubMed)

Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. In a randomised controlled trial, preterm babies undergoing ligation of a patent ductus arteriosus were given nitrous oxide and d-tubocurarine, with (n = 8) or without (n = 8) the addition of fentanyl (10 micrograms/kg intravenously) to the anaesthetic regimen. Major hormonal responses to surgery, as indicated by changes in plasma adrenaline, noradrenaline, glucagon, aldosterone (...) . The findings indicate that preterm babies mount a substantial stress response to surgery under anaesthesia with nitrous oxide and curare and that prevention of this response by fentanyl anaesthesia may be associated with an improved postoperative outcome.

1987 Lancet Controlled trial quality: uncertain

272. Hepatic glutathione S-transferase release after halothane anaesthesia: open randomised comparison with isoflurane. (PubMed)

Hepatic glutathione S-transferase release after halothane anaesthesia: open randomised comparison with isoflurane. Plasma concentrations of hepatic glutathione S-transferase (GST) are a more sensitive measure of acute hepatic damage than aminotransferase activity. Plasma GST concentrations have been measured by radioimmunoassay in an open randomised study after halothane or isoflurane anaesthesia. The concentration of GST was significantly increased after anaesthesia in patients who received (...) halothane in 30% oxygen/70% nitrous oxide (n = 37) and in patients who received halothane in 100% oxygen (n = 17). The frequency of abnormal GST concentrations, defined as 4 micrograms/l or more, was 35% and 24%, respectively. GST concentrations usually reached a peak 3-6 h after the end of anaesthesia. In 17 patients who received isoflurane in 30% oxygen/70% nitrous oxide, there was no significant rise in GST concentration and no patient had a concentration above 4 micrograms/l. No patient in any

1987 Lancet Controlled trial quality: uncertain