Latest & greatest articles for amoxicillin

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Top results for amoxicillin

61. Comparative efficacy of amoxicillin, cefuroxime and clarithromycin in the treatment of community-acquired pneumonia in children

Comparative efficacy of amoxicillin, cefuroxime and clarithromycin in the treatment of community-acquired pneumonia in children Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2003 NHS Economic Evaluation Database.

62. Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. (Abstract)

Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. For most infections, especially acute respiratory infections (ARIs), the recommended duration of therapy is not based on strong scientific or clinical criteria. Shorter courses of antibiotics for non-severe pneumonia would result in lower costs, enhance patient compliance, and might help to contain antimicrobial resistance. We aimed to compare the clinical (...) efficacy of 3-day and 5-day courses of amoxicillin in children with non-severe pneumonia.We recruited 2000 children, aged 2-59 months, with non-severe pneumonia (WHO criteria) diagnosed in the outpatient departments of seven hospitals. Patients were randomly assigned to 3 days or 5 days of treatment with oral amoxicillin. The primary outcome was treatment failure. Analyses were by intention to treat.We allocated 1000 children to 3 days of treatment and 1000 to 5 days. Treatment failed in 209 (21

2002 Lancet Controlled trial quality: predicted high

63. A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole

A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole A systematic comparison of triple therapies for treatment of Helicobacter pylori (...) infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole Janssen M J, Van Oijen A H, Verbeek A L, Jansen J B, De Boer W A Authors' objectives To evaluate whether there is a difference in the efficacy between triple therapies with proton-pump inhibitor (PPI) or ranitidine bismuth citrate (RBC) plus clarithromycin and either amoxicillin or a nitroimidazole, for the treatment of Helicobacter pylori (H. pylori) infection. Searching

2001 DARE.

64. Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial. (Abstract)

Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial. Emerging drug resistance threatens the effectiveness of existing therapies for pneumococcal infections. Modifying the dose and duration of antibiotic therapy may limit the spread of resistant pneumococci.To determine whether short-course, high-dose amoxicillin therapy reduces risk of posttreatment resistant pneumococcal carriage among children with respiratory tract (...) infections.Randomized trial conducted in an outpatient clinic in Santo Domingo, Dominican Republic, October 1999 through July 2000.Children aged 6 to 59 months who were receiving antibiotic prescriptions for respiratory tract illness (n = 795).Children were randomly assigned to receive 1 of 2 twice-daily regimens of amoxicillin: 90 mg/kg per day for 5 days (n = 398) or 40 mg/kg per day for 10 days (n = 397).Penicillin-nonsusceptible Streptococcus pneumoniae carriage, assessed in nasopharyngeal specimens collected

2001 JAMA Controlled trial quality: predicted high

65. Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients

Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Ricart E, Soriano G, Novella M T, Ortiz J, Sabat M, Kolle L, Sola-Vera J, Minana J, Dedeu J M, Gomez C, Barrio J L, Guarner C Record Status This is a critical abstract (...) of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Amoxicillin-clavulanic acid was compared to cefotaxime for the treatment of suspected bacterial infections in patients with cirrhosis. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population

2000 NHS Economic Evaluation Database.

66. The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis

The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis Lan A J, Colford J M Authors' objectives To compare cure (...) rates between once- or twice-daily (s.i.d. and b.i.d., respectively) and more frequent dosing schedules in the treatment of streptococcal tonsillopharyngitis. Searching MEDLINE and Dissertation Abstracts were searched to August 1998. For MEDLINE, the keywords were 'tonsillopharyngitis', 'pharyngitis', 'penicillin', 'amoxicillin' and 'clinical trials. For Dissertation Abstracts, combinations of the following words were used: 'streptococcus' or 'streptococcal' and 'penicillin' or 'amoxicillin

2000 DARE.

67. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. (Full text)

Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. To determine the effect of antibiotic treatment for acute otitis media in children between 6 months and 2 years of age.Practice based, double blind, randomised, placebo controlled trial.53 general practices in the Netherlands.240 children aged 6 months to 2 years with the diagnosis of acute otitis media.Amoxicillin 40 mg/kg/day in three doses.Persistent symptoms (...) at day four and duration of fever and pain or crying, or both. Otoscopy at days four and 11, tympanometry at six weeks, and use of analgesic.Persistent symptoms at day four were less common in the amoxicillin group (risk difference 13%; 95% confidence interval 1% to 25%). The median duration of fever was two days in the amoxicillin group versus three in the placebo group (P=0.004). No significant difference was observed in duration of pain or crying, but analgesic consumption was higher

2000 BMJ Controlled trial quality: predicted high PubMed abstract

68. Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes

Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Macy E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Elective penicillin skin testing (PenSTs) in advance of acute antibiotic need and (optional) amoxicillin challenge (AC) in patients with negative skin test responses. Patients were previously entered in a study of new penicillin reagents and received at least 1 prescription drug over a 2-year period

1998 NHS Economic Evaluation Database.

69. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group. (Abstract)

Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group. It is uncertain whether treatment of Helicobacter pylori infection relieves symptoms in patients with nonulcer, or functional, dyspepsia.We conducted a double-blind, multicenter trial of patients with H. pylori infection and dyspeptic symptoms (moderate-to-very-severe pain and discomfort centered (...) in the upper abdomen). Patients were excluded if they had a history of peptic ulcer disease or gastroesophageal reflux disease and had abnormal findings on upper endoscopy. Patients were randomly assigned to seven days of treatment with 20 mg of omeprazole twice daily, 1000 mg of amoxicillin twice daily, and 500 mg of clarithromycin twice daily or with omeprazole alone and then followed up for one year. Treatment success was defined as the absence of dyspeptic symptoms or the presence of minimal symptoms

1998 NEJM Controlled trial quality: predicted high

70. Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin

Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin Craig A M, Davey P, Malek M, Murray F Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The analysis was carried out for three distinct patient groups: patients with proven

1996 NHS Economic Evaluation Database.

71. Amoxicillin or erythromycin for the treatment of antenatal chlamydial infection: a meta-analysis

Amoxicillin or erythromycin for the treatment of antenatal chlamydial infection: a meta-analysis Amoxicillin or erythromycin for the treatment of antenatal chlamydial infection: a meta-analysis Amoxicillin or erythromycin for the treatment of antenatal chlamydial infection: a meta-analysis Turrentine M A, Newton E R Authors' objectives To compare the effectiveness of amoxicillin and erythromycin for the treatment of antenatal Chlamydia trachomatis infection. Searching MEDLINE and the Cochrane (...) Pregnancy and Childbirth Database were searched for English language abstracts using the MeSH 'pregnancy', 'chlamydia', 'erythromycin', 'amoxicillin', 'antenatal' and 'antibiotics'). Bibliographies of identified articles were also examined. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were included. Specific interventions included in the review Oral amoxicillin (500 mg three times daily for 7 days) or erythromycin (500 mg four times daily for 7

1995 DARE.

72. The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery

The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery Davey P G, Parker S E, Crombie I K, Jaderberg M Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Use of amoxicillin/clavulanic acid (ACA) as antibacterial prophylaxis in abdominal and gynaecological surgery. Type of intervention Prophylaxis. Economic study type Cost-effectiveness analysis. Study population Patients undergoing abdominal and gynaecological surgery

1995 NHS Economic Evaluation Database.

73. A clinical and economic comparison of roxithromycin 150 mg twice daily vs amoxicillin 500mg/calvulanic acid 125mg three times daily for the treatment of lower respiratory tract infections in general practice

A clinical and economic comparison of roxithromycin 150 mg twice daily vs amoxicillin 500mg/calvulanic acid 125mg three times daily for the treatment of lower respiratory tract infections in general practice A clinical and economic comparison of roxithromycin 150 mg twice daily vs amoxicillin 500mg/calvulanic acid 125mg three times daily for the treatment of lower respiratory tract infections in general practice A clinical and economic comparison of roxithromycin 150 mg twice daily vs (...) amoxicillin 500mg/calvulanic acid 125mg three times daily for the treatment of lower respiratory tract infections in general practice Karalus N C, Garrett J E, Lang S D, Scott W G, Leng R A, Kostalas G N, Cursons R T, Cooper B C, Scott H M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability

1994 NHS Economic Evaluation Database.

74. A pharmacoeconomic comparison of amoxicillin/clavulanate and cefpodoxime proxetil in the treatment of acute otitis media

A pharmacoeconomic comparison of amoxicillin/clavulanate and cefpodoxime proxetil in the treatment of acute otitis media A pharmacoeconomic comparison of amoxicillin/clavulanate and cefpodoxime proxetil in the treatment of acute otitis media A pharmacoeconomic comparison of amoxicillin/clavulanate and cefpodoxime proxetil in the treatment of acute otitis media Landholt T F, Kotschwar T R Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion (...) on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Treatment of acute otitis media in children with amoxicillin/ clavulanate potassium or cefpodoxime proxetil. Type of intervention Treatment Economic study type Cost-effectiveness analysis. Study population Children (males and females) were divided equally into two groups with an average

1994 NHS Economic Evaluation Database.

75. Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. (Abstract)

Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. Persistent infection with Helicobacter pylori is associated with the recurrence of duodenal ulcer. Whether the efficacy of bismuth therapy in reducing the rate of recurrence of duodenal ulcer is due to its antimicrobial effects on H. pylori or to a direct protective action on the mucosa is still a matter of debate.To study the effect of the eradication of H (...) . pylori on the recurrence of duodenal ulcer, we treated 104 patients with H. pylori infection and recurrent duodenal ulcer with either amoxicillin (750 mg three times daily) plus metronidazole (500 mg three times daily) or identical-appearing placebos, given orally for 12 days. All patients also received ranitidine (300 mg each night) for 6 or 10 weeks. Endoscopy was performed before treatment and periodically during follow-up for up to 12 months after healing.Among the 52 patients given antibiotics

1993 NEJM Controlled trial quality: uncertain

76. Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial. (Full text)

Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial. In a randomized, double-blind, placebo-controlled trial involving 518 infants and children who had otitis media with effusion ("secretory" otitis media), we evaluated the efficacy of a two-week course of amoxicillin (40 mg per kilogram of body weight per day) with and without a four-week course of an oral decongestant-antihistamine (...) combination. Among the 474 subjects who were evaluated at the four-week end point, the rate of resolution of middle-ear effusion was twice as high in those treated with amoxicillin, either with or without the decongestant-antihistamine, as in those who received placebo (P less than 0.001), but 69.8 percent of the amoxicillin-treated subjects still had effusion. Among both the amoxicillin-treated subjects and the placebo-treated subjects, resolution was more likely in those with initially unilateral

1987 NEJM Controlled trial quality: predicted high PubMed abstract

77. Single-dose therapy for cystitis in women. A comparison of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin. (Abstract)

Single-dose therapy for cystitis in women. A comparison of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin. We evaluated single-dose regimens of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin as treatment for acute cystitis in 38 women. The trial was prematurely stopped because of frequent treatment failures. At two days after treatment, all 13 patients given trimethoprim-sulfamethoxazole were cured, while four (31%) of 13 given amoxicillin and four (33%) of 12 given (...) cyclacillin had persistent bacteriuria. At two weeks, 11 (85%) of 13 patients given trimethoprim-sulfamethoxazole, six (50%) of 12 given amoxicillin, and three (30%) of ten given cyclacillin were cured. One patient with positive results of antibody-coated bacteria testing who was treated with cyclacillin had signs and symptoms of acute pyelonephritis three days after treatment, and two patients treated with amoxicillin and one treated with trimethoprim-sulfamethoxazole converted antibody-coated bacteria

1985 JAMA

78. Single-dose amoxicillin therapy for urinary tract infection. Multicenter trial using antibody-coated bacteria localization technique. (Abstract)

Single-dose amoxicillin therapy for urinary tract infection. Multicenter trial using antibody-coated bacteria localization technique. Urine specimens from 134 women with acute, uncomplicated urinary tract infection at three medical centers were examined by the antibody-coated bacteria (ACB) assay. Patients with negative assays (suggesting bladder infection alone) were randomized to receive either a single 3-g oral dose of amoxicillin trihydrate or conventional ten-day courses of sulfa (...) -methoxazole-trimethoprim or oral ampicillin sodium. Comparable results were obtained with the three regimens for ACG-negative infection: 90% eradication of the original organism with single-dose amoxicillin, 100% with sulfamethoxazole-trimethoprim, and 96% with ampicillin. The overall incidence of ACB positivity was 32.1%, ranging from 8% to 63% at the three institutions. This difference seemed to be related to the ease of access to medical care: women with easy access having low rates of ACB positivity

1980 JAMA Controlled trial quality: uncertain

79. Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. (Abstract)

Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. Urine specimens from 61 women with symptoms of cystitis who are infected with amoxicillin-sensitive organisms were examined by the antibody-coated bacteria assay. Patients with negative assays were randomized to receive either a single 3-g oral dose of amoxicillin or 10 days of amoxicillin, 250 mg, given by mouth four times per day (conventional therapy (...) ). Patients with positive assays received conventional therapy. All 43 patients without antibody-coated bacteria in the urine, 22 given single-dose therapy and 21 treated conventionally, were cured of their infection. Of 18 patients with antibody-coated bacteria, nine relapsed within one week of completion of conventional therapy. The results of the antibody-coated bacteria assay appear to predict the therapeutic response: both single-dose and conventional amoxicillin therapy are completely successful

1978 NEJM Controlled trial quality: uncertain