Latest & greatest articles for amoxicillin

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on amoxicillin or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on amoxicillin and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for amoxicillin

41. 5 days versus 3 day with amoxicillin treatment for non-severe pneumonia in young children

5 days versus 3 day with amoxicillin treatment for non-severe pneumonia in young children Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing

2013 PROSPERO

42. Randomised controlled trial: A 10-day course of amoxicillin does not reduce symptoms of acute rhinosinusitis at day 3 of treatment

Randomised controlled trial: A 10-day course of amoxicillin does not reduce symptoms of acute rhinosinusitis at day 3 of treatment A 10-day course of amoxicillin does not reduce symptoms of acute rhinosinusitis at day 3 of treatment | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here A 10-day course of amoxicillin does not reduce symptoms of acute rhinosinusitis at day 3 of treatment Article Text Therapeutics Randomised controlled

2013 Evidence-Based Medicine

43. Amoxicillin for acute rhinosinusitis: a randomized controlled trial. (Full text)

Amoxicillin for acute rhinosinusitis: a randomized controlled trial. Evidence to support antibiotic treatment for acute rhinosinusitis is limited, yet antibiotics are commonly used.To determine the incremental effect of amoxicillin treatment over symptomatic treatments for adults with clinically diagnosed acute rhinosinusitis.A randomized, placebo-controlled trial of adults with uncomplicated, acute rhinosinusitis were recruited from 10 community practices in Missouri between November 1, 2006 (...) , and May 1, 2009.Ten-day course of either amoxicillin (1500 mg/d) or placebo administered in 3 doses per day. All patients received a 5- to 7-day supply of symptomatic treatments for pain, fever, cough, and nasal congestion to use as needed.The primary outcome was improvement in disease-specific quality of life after 3 to 4 days of treatment assessed with the Sinonasal Outcome Test-16 (minimally important difference of 0.5 units on a 0-3 scale). Secondary outcomes included the patient's retrospective

2012 JAMA Controlled trial quality: predicted high PubMed abstract

44. Effectiveness of community case management of severe pneumonia with oral amoxicillin in children aged 2-59 months in Matiari district, rural Pakistan: a cluster-randomised controlled trial. (Abstract)

Effectiveness of community case management of severe pneumonia with oral amoxicillin in children aged 2-59 months in Matiari district, rural Pakistan: a cluster-randomised controlled trial. Pneumonia is a leading global cause of morbidity and mortality in children younger than 5 years. In Pakistan, the proportion of deaths due to pneumonia is higher in rural areas than it is in urban areas, with a substantial proportion of individuals dying at home because referral for care is problematic (...) screened by LHWs and those diagnosed with severe pneumonia were prescribed oral amoxicillin syrup (90 mg/kg per day in two doses) for 5 days at home. Children in control clusters were given one dose of oral co-trimoxazole and were referred to their nearest health facility for admission and intravenous antibiotics, as per government policy. In both groups, follow-up visits at home were done at days 2, 3, 6, and 14 by LHW. The primary outcome was treatment failure by day 6 after enrolment. We matched

2012 Lancet Controlled trial quality: predicted high

45. Randomised controlled trial: Training birth attendants in rural Zambia in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality

Randomised controlled trial: Training birth attendants in rural Zambia in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality Training birth attendants in rural Zambia in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings (...) in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality Article Text Therapeutics Randomised controlled trial Training birth attendants in rural Zambia in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality David R Marsh 1 , Stephen N Wall 2 Statistics from Altmetric.com Commentary on: Gill CJ , Phiri-Mazala G , Guerina NG , et al . Effect of training traditional birth attendants

2011 Evidence-Based Medicine

46. Randomised controlled trial: Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select children with acute otitis media and increases risk of diarrhoea

Randomised controlled trial: Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select children with acute otitis media and increases risk of diarrhoea Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select children with acute otitis media and increases risk of diarrhoea | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select

2011 Evidence-Based Medicine

47. Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial. (Abstract)

Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial. Researchers have suggested that antibiotics could cure acute appendicitis. We assessed the efficacy of amoxicillin plus clavulanic acid by comparison with emergency appendicectomy for treatment of patients with uncomplicated acute appendicitis.In this open-label, non-inferiority, randomised trial, adult patients (aged 18-68 years (...) ) with uncomplicated acute appendicitis, as assessed by CT scan, were enrolled at six university hospitals in France. A computer-generated randomisation sequence was used to allocate patients randomly in a 1:1 ratio to receive amoxicillin plus clavulanic acid (3 g per day) for 8-15 days or emergency appendicectomy. The primary endpoint was occurrence of postintervention peritonitis within 30 days of treatment initiation. Non-inferiority was shown if the upper limit of the two-sided 95% CI for the difference

2011 Lancet Controlled trial quality: predicted high

48. Community case management of severe pneumonia with oral amoxicillin in children aged 2-59 months in Haripur district, Pakistan: a cluster randomised trial. (Full text)

Community case management of severe pneumonia with oral amoxicillin in children aged 2-59 months in Haripur district, Pakistan: a cluster randomised trial. First dose oral co-trimoxazole and referral are recommended for WHO-defined severe pneumonia. Difficulties with referral compliance are reported in many low-resource settings, resulting in low access to appropriate treatment. The objective in this study was to assess whether community case management by lady health workers (LHWs) with oral (...) amoxicillin in children with severe pneumonia was equivalent to current standard of care.In Haripur district, Pakistan, 28 clusters were randomly assigned with stratification in a 1:1 ratio to intervention and control clusters by use of a computer-generated randomisation sequence. Children were included in the study if they were aged 2-59 months with WHO-defined severe pneumonia and living in the study area. In the intervention clusters, community-based LHWs provided mothers with oral amoxicillin (80-90

2011 Lancet Controlled trial quality: predicted high PubMed abstract

49. Effectiveness of amoxicillin/clavulanate potassium in the treatment of acute bacterial sinusitis in children (Abstract)

Effectiveness of amoxicillin/clavulanate potassium in the treatment of acute bacterial sinusitis in children The role of antibiotic therapy in managing acute bacterial sinusitis (ABS) in children is controversial. The purpose of this study was to determine the effectiveness of high-dose amoxicillin/potassium clavulanate in the treatment of children diagnosed with ABS.This was a randomized, double-blind, placebo-controlled study. Children 1 to 10 years of age with a clinical presentation (...) compatible with ABS were eligible for participation. Patients were stratified according to age (<6 or >or=6 years) and clinical severity and randomly assigned to receive either amoxicillin (90 mg/kg) with potassium clavulanate (6.4 mg/kg) or placebo. A symptom survey was performed on days 0, 1, 2, 3, 5, 7, 10, 20, and 30. Patients were examined on day 14. Children's conditions were rated as cured, improved, or failed according to scoring rules.Two thousand one hundred thirty-five children

2009 EvidenceUpdates Controlled trial quality: predicted high

50. Placebo found equivalent to amoxicillin for treatment of acute bronchitis in Nairobi, Kenya: a triple blind, randomised, equivalence trial (Full text)

Placebo found equivalent to amoxicillin for treatment of acute bronchitis in Nairobi, Kenya: a triple blind, randomised, equivalence trial Antibiotic treatment is not recommended for acute bronchitis in immunocompetent patients in industrialised countries. Whether these recommendations are relevant to the developing world and to immunocompromised patients is unknown.Randomised, triple blind, placebo controlled equivalence trial of amoxicillin compared with placebo in 660 adults presenting (...) to two outpatient clinics in Nairobi, Kenya, with acute bronchitis but without evidence of chronic lung disease.The primary study end point was clinical cure, as defined by a >or=75% reduction in a validated Acute Bronchitis Severity Score by 14 days; analysis was by intention to treat with equivalence defined as amoxicillin and placebo arms were 81.7% and 84.0%, respectively (difference 2.3%, 95% CI -8.6% to 4.0%). Of 131 HIV infected

2008 EvidenceUpdates Controlled trial quality: predicted high PubMed abstract

51. Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trial. (Abstract)

Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trial. WHO case management guidelines for severe pneumonia involve referral to hospital for treatment with parenteral antibiotics. If equally as effective as parenteral treatment, home-based oral antibiotic treatment could reduce referral, admission, and treatment costs. Our aim was to determine whether home treatment with high-dose oral amoxicillin and inpatient treatment (...) with parenteral ampicillin were equivalent for the treatment of severe pneumonia in children.This randomised, open-label equivalency trial was done at seven study sites in Pakistan. 2037 children aged 3-59 months with severe pneumonia were randomly allocated to either initial hospitalisation and parenteral ampicillin (100 mg/kg per day in four doses) for 48 h, followed by 3 days of oral amoxicillin (80-90 mg/kg per day; n=1012) or to home-based treatment for 5 days with oral amoxicillin (80-90 mg/kg per day

2008 Lancet Controlled trial quality: predicted high

52. Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis (Full text)

Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis Consensus Guidelines for Dosing of Amoxicillin-Clavulanate in Melioidosis | The American Journal of Tropical Medicine and Hygiene 1921 Toggle search navigation Toggle main navigation Follow us: Go Toggle navigation Tools Toggle navigation Share Follow us: Username: Password: Login Share Tools /recommendto/form?webId=%2Fcontent%2Fjournals%2F14761645&title=The+American+Journal+of+Tropical+Medicine+and+Hygiene&issn=0002-9637 (...) &eissn=1476-1645 The American Journal of Tropical Medicine and Hygiene — Recommend this title to your library Article f Consensus Guidelines for Dosing of Amoxicillin-Clavulanate in Melioidosis 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1,* View Affiliations Hide Affiliations Affiliations: 1 Reprint requests: Bart J. Currie, Menzies School of Health Research, PO Box 41096, Casuarina NT 0811. E-mail: Publisher: Source: , , 1 Feb 2008, p. 208 - 209 Abstract Abstract Melioidosis is an infectious disease endemic

2008 Clinical Practice Guidelines Portal PubMed abstract

53. Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo

Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo Article Text

2007 Evidence-Based Medicine

54. Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US

Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Schmier J K, Waycaster C R, Wall G M Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study compared the cost-effectiveness of ciprofloxacin-dexamethasone ear drops with oral amoxicillin-clavulanic acid for the treatment of patients with acute otitis media in the tympanostomy tube (AOMT

2007 NHS Economic Evaluation Database.

55. Single-dose azithromycin versus erythromycin or amoxicillin for Chlamydia trachomatis infection during pregnancy: a meta-analysis of randomised controlled trials

Single-dose azithromycin versus erythromycin or amoxicillin for Chlamydia trachomatis infection during pregnancy: a meta-analysis of randomised controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

56. Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia

Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community (...) acquired pneumonia Yaqub A, Khan Z Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined the early switch from intravenous to oral amoxicillin-clavulanate in the treatment of hospitalised patients with community-acquired

2005 NHS Economic Evaluation Database.

57. Amoxicillin-clavulanate vs ciprofloxacin for the treatment of uncomplicated cystitis in women: a randomized trial. (Full text)

Amoxicillin-clavulanate vs ciprofloxacin for the treatment of uncomplicated cystitis in women: a randomized trial. The high prevalence of resistance to trimethoprim-sulfamethoxazole and other antimicrobials among Escherichia coli causing acute cystitis in women has led to increased use of alternative antibiotics. One such antibiotic, amoxicillin-clavulanate, has not been well studied.To compare the efficacy of a 3-day regimen of amoxicillin-clavulanate to that of a 3-day regimen (...) of ciprofloxacin in the treatment of acute cystitis in women. The primary study hypothesis was that the amoxicillin-clavulanate and ciprofloxacin treatment groups would differ in clinical cure.Randomized, single-blind treatment trial of 370 women, aged 18 to 45 years, with symptoms of acute uncomplicated cystitis and a urine culture with at least 10(2) colony-forming units of uropathogens per milliliter from a university student health center or a health maintenance organization.Women were randomly assigned

2005 JAMA Controlled trial quality: predicted high PubMed abstract

58. Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. (Abstract)

Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. Injectable penicillin is the recommended treatment for WHO-defined severe pneumonia (lower chest indrawing). If oral amoxicillin proves equally effective, it could reduce referral, admission, and treatment costs. We aimed to determine whether oral amoxicillin and parenteral penicillin were equivalent in the treatment of severe pneumonia in children aged (...) 3-59 months.This multicentre, randomised, open-label equivalency study was undertaken at tertiary-care centres in eight developing countries in Africa, Asia, and South America. Children aged 3-59 months with severe pneumonia were admitted for 48 h and, if symptoms improved, were discharged with a 5-day course of oral amoxicillin. 1702 children were randomly allocated to receive either oral amoxicillin (n=857) or parenteral penicillin (n=845) for 48 h. Follow-up assessments were done at 5 and 14

2004 Lancet Controlled trial quality: predicted high

59. Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial

Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2004 NHS Economic Evaluation Database.

60. Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial. (Full text)

Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial. To assess the efficacy of three days versus five days of treatment with oral amoxicillin for curing non-severe pneumonia in children.Randomised, double blind, placebo controlled multicentre trial.Outpatient departments of seven referral hospitals in India.2188 children aged 2-59 months, 1095 given three days of treatment and 1093 given five days.Oral (...) amoxicillin 31-54 mg/kg/day in three divided doses.Treatment failure: defined as development of chest indrawing, convulsions, drowsiness, or inability to drink at any time; respiratory rate above age specific cut points on day 3 or later; or oxygen saturation by pulse oximetry < 90% on day 3.The clinical cure rates with three days and five days of treatment were 89.5% and 89.9%, respectively (absolute difference 0.4 (95% confidence interval--2.1 to 3.0)). Adherence to treatment regimen was 94% and 85

2004 BMJ Controlled trial quality: predicted high PubMed abstract