Latest & greatest articles for amoxicillin

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Top results for amoxicillin

41. Placebo found equivalent to amoxicillin for treatment of acute bronchitis in Nairobi, Kenya: a triple blind, randomised, equivalence trial (PubMed)

Placebo found equivalent to amoxicillin for treatment of acute bronchitis in Nairobi, Kenya: a triple blind, randomised, equivalence trial Antibiotic treatment is not recommended for acute bronchitis in immunocompetent patients in industrialised countries. Whether these recommendations are relevant to the developing world and to immunocompromised patients is unknown.Randomised, triple blind, placebo controlled equivalence trial of amoxicillin compared with placebo in 660 adults presenting (...) to two outpatient clinics in Nairobi, Kenya, with acute bronchitis but without evidence of chronic lung disease.The primary study end point was clinical cure, as defined by a >or=75% reduction in a validated Acute Bronchitis Severity Score by 14 days; analysis was by intention to treat with equivalence defined as amoxicillin and placebo arms were 81.7% and 84.0%, respectively (difference 2.3%, 95% CI -8.6% to 4.0%). Of 131 HIV infected

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2008 EvidenceUpdates Controlled trial quality: predicted high

42. Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media. (PubMed)

Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media. Acute otitis media (AOM) is a common problem in children, for which the antibiotic amoxicillin, with or without clavulanate, is frequently prescribed.To compare the effectiveness of one or two daily doses with three or four daily doses of amoxicillin, with or without clavulanate, for the treatment of AOM in children.We searched the Cochrane Central Register of Controlled (...) differences.This review showed insufficient evidence to judge whether once or twice daily doses of amoxicillin, with or without clavulanate, were comparable with three or four daily doses for the treatment of AOM. The evidence appears to be biased and therefore no firm conclusions can be drawn.

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2008 Cochrane

43. Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis

Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis Consensus Guidelines for Dosing of Amoxicillin-Clavulanate in Melioidosis | The American Journal of Tropical Medicine and Hygiene 1921 Toggle search navigation Toggle main navigation Follow us: Go Toggle navigation Tools Toggle navigation Share Follow us: Username: Password: Login Share Tools /recommendto/form?webId=%2Fcontent%2Fjournals%2F14761645&title=The+American+Journal+of+Tropical+Medicine+and+Hygiene&issn=0002-9637 (...) &eissn=1476-1645 The American Journal of Tropical Medicine and Hygiene — Recommend this title to your library Article f Consensus Guidelines for Dosing of Amoxicillin-Clavulanate in Melioidosis 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1,* View Affiliations Hide Affiliations Affiliations: 1 Reprint requests: Bart J. Currie, Menzies School of Health Research, PO Box 41096, Casuarina NT 0811. E-mail: Publisher: Source: , , 1 Feb 2008, p. 208 - 209 Abstract Abstract Melioidosis is an infectious disease endemic

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2008 Clinical Practice Guidelines Portal

44. Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trial. (PubMed)

Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trial. WHO case management guidelines for severe pneumonia involve referral to hospital for treatment with parenteral antibiotics. If equally as effective as parenteral treatment, home-based oral antibiotic treatment could reduce referral, admission, and treatment costs. Our aim was to determine whether home treatment with high-dose oral amoxicillin and inpatient treatment (...) with parenteral ampicillin were equivalent for the treatment of severe pneumonia in children.This randomised, open-label equivalency trial was done at seven study sites in Pakistan. 2037 children aged 3-59 months with severe pneumonia were randomly allocated to either initial hospitalisation and parenteral ampicillin (100 mg/kg per day in four doses) for 48 h, followed by 3 days of oral amoxicillin (80-90 mg/kg per day; n=1012) or to home-based treatment for 5 days with oral amoxicillin (80-90 mg/kg per day

2008 Lancet Controlled trial quality: predicted high

45. Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo

Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Mometasone furoate nasal spray was more effective for symptom relief of acute rhinosinusitis than amoxicillin or placebo Article Text

2007 Evidence-Based Medicine (Requires free registration)

46. Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US

Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Cost of ciprofloxacin/dexamethasone vs amoxicillin/clavulanic acid for the treatment of acute otitis media in tympanostomy tube patients in the US Schmier J K, Waycaster C R, Wall G M Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study compared the cost-effectiveness of ciprofloxacin-dexamethasone ear drops with oral amoxicillin-clavulanic acid for the treatment of patients with acute otitis media in the tympanostomy tube (AOMT

2007 NHS Economic Evaluation Database.

47. Single-dose azithromycin versus erythromycin or amoxicillin for Chlamydia trachomatis infection during pregnancy: a meta-analysis of randomised controlled trials

Single-dose azithromycin versus erythromycin or amoxicillin for Chlamydia trachomatis infection during pregnancy: a meta-analysis of randomised controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

48. Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia

Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community acquired pneumonia Comparison of early intravenous to oral switch amoxicillin/clavulanate with parenteral ceftriaxone in treatment of hospitalized patients with community (...) acquired pneumonia Yaqub A, Khan Z Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined the early switch from intravenous to oral amoxicillin-clavulanate in the treatment of hospitalised patients with community-acquired

2005 NHS Economic Evaluation Database.

49. Amoxicillin-clavulanate vs ciprofloxacin for the treatment of uncomplicated cystitis in women: a randomized trial. (PubMed)

Amoxicillin-clavulanate vs ciprofloxacin for the treatment of uncomplicated cystitis in women: a randomized trial. The high prevalence of resistance to trimethoprim-sulfamethoxazole and other antimicrobials among Escherichia coli causing acute cystitis in women has led to increased use of alternative antibiotics. One such antibiotic, amoxicillin-clavulanate, has not been well studied.To compare the efficacy of a 3-day regimen of amoxicillin-clavulanate to that of a 3-day regimen (...) of ciprofloxacin in the treatment of acute cystitis in women. The primary study hypothesis was that the amoxicillin-clavulanate and ciprofloxacin treatment groups would differ in clinical cure.Randomized, single-blind treatment trial of 370 women, aged 18 to 45 years, with symptoms of acute uncomplicated cystitis and a urine culture with at least 10(2) colony-forming units of uropathogens per milliliter from a university student health center or a health maintenance organization.Women were randomly assigned

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2005 JAMA Controlled trial quality: predicted high

50. Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. (PubMed)

Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. Injectable penicillin is the recommended treatment for WHO-defined severe pneumonia (lower chest indrawing). If oral amoxicillin proves equally effective, it could reduce referral, admission, and treatment costs. We aimed to determine whether oral amoxicillin and parenteral penicillin were equivalent in the treatment of severe pneumonia in children aged (...) 3-59 months.This multicentre, randomised, open-label equivalency study was undertaken at tertiary-care centres in eight developing countries in Africa, Asia, and South America. Children aged 3-59 months with severe pneumonia were admitted for 48 h and, if symptoms improved, were discharged with a 5-day course of oral amoxicillin. 1702 children were randomly allocated to receive either oral amoxicillin (n=857) or parenteral penicillin (n=845) for 48 h. Follow-up assessments were done at 5 and 14

2004 Lancet Controlled trial quality: predicted high

51. Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial. (PubMed)

Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial. To assess the efficacy of three days versus five days of treatment with oral amoxicillin for curing non-severe pneumonia in children.Randomised, double blind, placebo controlled multicentre trial.Outpatient departments of seven referral hospitals in India.2188 children aged 2-59 months, 1095 given three days of treatment and 1093 given five days.Oral (...) amoxicillin 31-54 mg/kg/day in three divided doses.Treatment failure: defined as development of chest indrawing, convulsions, drowsiness, or inability to drink at any time; respiratory rate above age specific cut points on day 3 or later; or oxygen saturation by pulse oximetry < 90% on day 3.The clinical cure rates with three days and five days of treatment were 89.5% and 89.9%, respectively (absolute difference 0.4 (95% confidence interval--2.1 to 3.0)). Adherence to treatment regimen was 94% and 85

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2004 BMJ Controlled trial quality: predicted high

52. Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial

Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2004 NHS Economic Evaluation Database.

53. Comparative efficacy of amoxicillin, cefuroxime and clarithromycin in the treatment of community-acquired pneumonia in children

Comparative efficacy of amoxicillin, cefuroxime and clarithromycin in the treatment of community-acquired pneumonia in children Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2003 NHS Economic Evaluation Database.

54. Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. (PubMed)

Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. For most infections, especially acute respiratory infections (ARIs), the recommended duration of therapy is not based on strong scientific or clinical criteria. Shorter courses of antibiotics for non-severe pneumonia would result in lower costs, enhance patient compliance, and might help to contain antimicrobial resistance. We aimed to compare the clinical (...) efficacy of 3-day and 5-day courses of amoxicillin in children with non-severe pneumonia.We recruited 2000 children, aged 2-59 months, with non-severe pneumonia (WHO criteria) diagnosed in the outpatient departments of seven hospitals. Patients were randomly assigned to 3 days or 5 days of treatment with oral amoxicillin. The primary outcome was treatment failure. Analyses were by intention to treat.We allocated 1000 children to 3 days of treatment and 1000 to 5 days. Treatment failed in 209 (21

2002 Lancet Controlled trial quality: predicted high

55. A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole

A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole A systematic comparison of triple therapies for treatment of Helicobacter pylori (...) infection with proton pump inhibitor/ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole Janssen M J, Van Oijen A H, Verbeek A L, Jansen J B, De Boer W A Authors' objectives To evaluate whether there is a difference in the efficacy between triple therapies with proton-pump inhibitor (PPI) or ranitidine bismuth citrate (RBC) plus clarithromycin and either amoxicillin or a nitroimidazole, for the treatment of Helicobacter pylori (H. pylori) infection. Searching

2001 DARE.

56. Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial. (PubMed)

Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial. Emerging drug resistance threatens the effectiveness of existing therapies for pneumococcal infections. Modifying the dose and duration of antibiotic therapy may limit the spread of resistant pneumococci.To determine whether short-course, high-dose amoxicillin therapy reduces risk of posttreatment resistant pneumococcal carriage among children with respiratory tract (...) infections.Randomized trial conducted in an outpatient clinic in Santo Domingo, Dominican Republic, October 1999 through July 2000.Children aged 6 to 59 months who were receiving antibiotic prescriptions for respiratory tract illness (n = 795).Children were randomly assigned to receive 1 of 2 twice-daily regimens of amoxicillin: 90 mg/kg per day for 5 days (n = 398) or 40 mg/kg per day for 10 days (n = 397).Penicillin-nonsusceptible Streptococcus pneumoniae carriage, assessed in nasopharyngeal specimens collected

2001 JAMA Controlled trial quality: predicted high

57. Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients

Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Amoxicillin-clavulanic acid versus cefotaxime in the therapy of bacterial infections in cirrhotic patients Ricart E, Soriano G, Novella M T, Ortiz J, Sabat M, Kolle L, Sola-Vera J, Minana J, Dedeu J M, Gomez C, Barrio J L, Guarner C Record Status This is a critical abstract (...) of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Amoxicillin-clavulanic acid was compared to cefotaxime for the treatment of suspected bacterial infections in patients with cirrhosis. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population

2000 NHS Economic Evaluation Database.

58. The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis

The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis Lan A J, Colford J M Authors' objectives To compare cure (...) rates between once- or twice-daily (s.i.d. and b.i.d., respectively) and more frequent dosing schedules in the treatment of streptococcal tonsillopharyngitis. Searching MEDLINE and Dissertation Abstracts were searched to August 1998. For MEDLINE, the keywords were 'tonsillopharyngitis', 'pharyngitis', 'penicillin', 'amoxicillin' and 'clinical trials. For Dissertation Abstracts, combinations of the following words were used: 'streptococcus' or 'streptococcal' and 'penicillin' or 'amoxicillin

2000 DARE.

59. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. (PubMed)

Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. To determine the effect of antibiotic treatment for acute otitis media in children between 6 months and 2 years of age.Practice based, double blind, randomised, placebo controlled trial.53 general practices in the Netherlands.240 children aged 6 months to 2 years with the diagnosis of acute otitis media.Amoxicillin 40 mg/kg/day in three doses.Persistent symptoms (...) at day four and duration of fever and pain or crying, or both. Otoscopy at days four and 11, tympanometry at six weeks, and use of analgesic.Persistent symptoms at day four were less common in the amoxicillin group (risk difference 13%; 95% confidence interval 1% to 25%). The median duration of fever was two days in the amoxicillin group versus three in the placebo group (P=0.004). No significant difference was observed in duration of pain or crying, but analgesic consumption was higher

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2000 BMJ Controlled trial quality: predicted high

60. Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes

Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Elective penicillin skin testing and amoxicillin challenge: effect on outpatient antibiotic use, cost, and clinical outcomes Macy E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Elective penicillin skin testing (PenSTs) in advance of acute antibiotic need and (optional) amoxicillin challenge (AC) in patients with negative skin test responses. Patients were previously entered in a study of new penicillin reagents and received at least 1 prescription drug over a 2-year period

1998 NHS Economic Evaluation Database.